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Side-by-side financial comparison of Gossamer Bio, Inc. (GOSS) and Spire Global, Inc. (SPIR). Click either name above to swap in a different company.
Spire Global, Inc. is the larger business by last-quarter revenue ($15.8M vs $13.8M, roughly 1.1× Gossamer Bio, Inc.). Spire Global, Inc. runs the higher net margin — -176.6% vs -342.3%, a 165.7% gap on every dollar of revenue. On growth, Gossamer Bio, Inc. posted the faster year-over-year revenue change (47.1% vs -26.9%).
Gossamer Bio, Inc. is a clinical-stage biopharmaceutical company focused on discovering, developing and commercializing novel therapeutics for patients with serious immunology, inflammation and oncology conditions. It advances a pipeline of proprietary product candidates across multiple clinical phases, primarily serving healthcare markets in North America and other global regions.
Spire Global, Inc. is a space-to-cloud data and analytics company that specializes in the tracking of global data sets powered by a large constellation of nanosatellites, such as the tracking of maritime, aviation and weather patterns.
GOSS vs SPIR — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $13.8M | $15.8M |
| Net Profit | $-47.2M | $-28.0M |
| Gross Margin | — | 40.2% |
| Operating Margin | -333.6% | -164.1% |
| Net Margin | -342.3% | -176.6% |
| Revenue YoY | 47.1% | -26.9% |
| Net Profit YoY | -43.0% | 42.7% |
| EPS (diluted) | $-0.21 | $-0.85 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $13.8M | $15.8M | ||
| Q3 25 | $13.3M | $12.7M | ||
| Q2 25 | — | $19.2M | ||
| Q1 25 | — | $23.9M | ||
| Q4 24 | — | $21.7M | ||
| Q3 24 | — | $28.6M | ||
| Q2 24 | $95.8M | $25.4M | ||
| Q1 24 | $0 | $34.8M |
| Q4 25 | $-47.2M | $-28.0M | ||
| Q3 25 | $-48.2M | $-19.7M | ||
| Q2 25 | — | $119.6M | ||
| Q1 25 | — | $-20.7M | ||
| Q4 24 | — | $-48.8M | ||
| Q3 24 | — | $-12.5M | ||
| Q2 24 | $49.2M | $-16.6M | ||
| Q1 24 | $-41.9M | $-25.5M |
| Q4 25 | — | 40.2% | ||
| Q3 25 | — | 36.6% | ||
| Q2 25 | — | 48.9% | ||
| Q1 25 | — | 36.8% | ||
| Q4 24 | — | 32.4% | ||
| Q3 24 | — | 44.5% | ||
| Q2 24 | — | 43.0% | ||
| Q1 24 | — | 26.5% |
| Q4 25 | -333.6% | -164.1% | ||
| Q3 25 | -369.4% | -166.1% | ||
| Q2 25 | — | -122.7% | ||
| Q1 25 | — | -106.5% | ||
| Q4 24 | — | -144.1% | ||
| Q3 24 | — | -48.0% | ||
| Q2 24 | 54.3% | -48.6% | ||
| Q1 24 | — | -34.4% |
| Q4 25 | -342.3% | -176.6% | ||
| Q3 25 | -362.7% | -155.3% | ||
| Q2 25 | — | 623.4% | ||
| Q1 25 | — | -86.5% | ||
| Q4 24 | — | -225.2% | ||
| Q3 24 | — | -43.7% | ||
| Q2 24 | 51.4% | -65.2% | ||
| Q1 24 | — | -73.3% |
| Q4 25 | $-0.21 | $-0.85 | ||
| Q3 25 | $-0.21 | $-0.61 | ||
| Q2 25 | — | $3.72 | ||
| Q1 25 | — | $-0.77 | ||
| Q4 24 | — | $-1.93 | ||
| Q3 24 | — | $-0.50 | ||
| Q2 24 | $0.22 | $-0.68 | ||
| Q1 24 | $-0.19 | $-1.17 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $136.9M | $81.8M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $-122.8M | $112.9M |
| Total Assets | $172.2M | $211.0M |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $136.9M | $81.8M | ||
| Q3 25 | $180.2M | $96.8M | ||
| Q2 25 | — | $117.6M | ||
| Q1 25 | — | $35.9M | ||
| Q4 24 | — | $19.2M | ||
| Q3 24 | — | $36.6M | ||
| Q2 24 | $354.5M | $45.8M | ||
| Q1 24 | $244.4M | $63.7M |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | $103.7M | ||
| Q4 24 | — | $103.1M | ||
| Q3 24 | — | $4.9M | ||
| Q2 24 | — | $4.9M | ||
| Q1 24 | — | $123.1M |
| Q4 25 | $-122.8M | $112.9M | ||
| Q3 25 | $-82.3M | $133.1M | ||
| Q2 25 | — | $149.2M | ||
| Q1 25 | — | $3.7M | ||
| Q4 24 | — | $-11.7M | ||
| Q3 24 | — | $30.8M | ||
| Q2 24 | $81.5M | $40.3M | ||
| Q1 24 | $26.7M | $52.5M |
| Q4 25 | $172.2M | $211.0M | ||
| Q3 25 | $208.8M | $224.3M | ||
| Q2 25 | — | $239.5M | ||
| Q1 25 | — | $208.8M | ||
| Q4 24 | — | $193.6M | ||
| Q3 24 | — | $224.2M | ||
| Q2 24 | $373.4M | $230.8M | ||
| Q1 24 | $259.4M | $252.3M |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | 27.92× | ||
| Q4 24 | — | — | ||
| Q3 24 | — | 0.16× | ||
| Q2 24 | — | 0.12× | ||
| Q1 24 | — | 2.35× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-48.3M | $-4.3M |
| Free Cash FlowOCF − Capex | — | $-16.2M |
| FCF MarginFCF / Revenue | — | -102.1% |
| Capex IntensityCapex / Revenue | 0.0% | 75.1% |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | — | $-92.6M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-48.3M | $-4.3M | ||
| Q3 25 | $-36.2M | $-12.0M | ||
| Q2 25 | — | $-35.1M | ||
| Q1 25 | — | $-8.4M | ||
| Q4 24 | — | $-19.2M | ||
| Q3 24 | — | $14.0M | ||
| Q2 24 | $116.3M | $-4.4M | ||
| Q1 24 | $-52.3M | $-8.8M |
| Q4 25 | — | $-16.2M | ||
| Q3 25 | — | $-20.4M | ||
| Q2 25 | — | $-38.7M | ||
| Q1 25 | — | $-17.3M | ||
| Q4 24 | — | $-24.3M | ||
| Q3 24 | — | $5.1M | ||
| Q2 24 | — | $-9.9M | ||
| Q1 24 | — | $-15.9M |
| Q4 25 | — | -102.1% | ||
| Q3 25 | — | -161.3% | ||
| Q2 25 | — | -201.7% | ||
| Q1 25 | — | -72.6% | ||
| Q4 24 | — | -112.2% | ||
| Q3 24 | — | 17.8% | ||
| Q2 24 | — | -39.0% | ||
| Q1 24 | — | -45.7% |
| Q4 25 | 0.0% | 75.1% | ||
| Q3 25 | 0.0% | 66.2% | ||
| Q2 25 | — | 18.8% | ||
| Q1 25 | — | 37.3% | ||
| Q4 24 | — | 23.5% | ||
| Q3 24 | — | 31.2% | ||
| Q2 24 | 0.0% | 21.8% | ||
| Q1 24 | — | 20.3% |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | -0.29× | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | — | — | ||
| Q2 24 | 2.36× | — | ||
| Q1 24 | — | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
