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Side-by-side financial comparison of Global Payments (GPN) and Vertex Pharmaceuticals (VRTX). Click either name above to swap in a different company.

Vertex Pharmaceuticals is the larger business by last-quarter revenue ($3.0B vs $3.0B, roughly 1.0× Global Payments). Vertex Pharmaceuticals runs the higher net margin — 34.5% vs -59.9%, a 94.4% gap on every dollar of revenue. On growth, Global Payments posted the faster year-over-year revenue change (63.1% vs 7.8%). Over the past eight quarters, Global Payments's revenue compounded faster (7.5% CAGR vs 6.3%).

Global Payments Inc. is an American multinational financial technology company that provides payment technology and services to merchants, issuers and consumers. In June 2021, the company was named to the Fortune 500. The company processes payments made through credit cards, debit cards, and digital and contactless payments.

Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, Oxfordshire, England.

GPN vs VRTX — Head-to-Head

Bigger by revenue
VRTX
VRTX
1.0× larger
VRTX
$3.0B
$3.0B
GPN
Growing faster (revenue YoY)
GPN
GPN
+55.3% gap
GPN
63.1%
7.8%
VRTX
Higher net margin
VRTX
VRTX
94.4% more per $
VRTX
34.5%
-59.9%
GPN
Faster 2-yr revenue CAGR
GPN
GPN
Annualised
GPN
7.5%
6.3%
VRTX

Income Statement — Q1 FY2026 vs Q1 FY2026

Metric
GPN
GPN
VRTX
VRTX
Revenue
$3.0B
$3.0B
Net Profit
$-1.8B
$1.0B
Gross Margin
86.8%
Operating Margin
12.5%
38.1%
Net Margin
-59.9%
34.5%
Revenue YoY
63.1%
7.8%
Net Profit YoY
-688.7%
59.6%
EPS (diluted)
$-6.59
$4.02

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
GPN
GPN
VRTX
VRTX
Q1 26
$3.0B
$3.0B
Q4 25
$1.3B
$3.2B
Q3 25
$2.0B
$3.1B
Q2 25
$2.0B
$3.0B
Q1 25
$2.4B
$2.8B
Q4 24
$2.5B
$2.9B
Q3 24
$2.6B
$2.8B
Q2 24
$2.6B
$2.6B
Net Profit
GPN
GPN
VRTX
VRTX
Q1 26
$-1.8B
$1.0B
Q4 25
$217.5M
$1.2B
Q3 25
$635.2M
$1.1B
Q2 25
$241.6M
$1.0B
Q1 25
$305.7M
$646.3M
Q4 24
$567.2M
$913.0M
Q3 24
$315.1M
$1.0B
Q2 24
$374.8M
$-3.6B
Gross Margin
GPN
GPN
VRTX
VRTX
Q1 26
86.8%
Q4 25
89.7%
85.4%
Q3 25
72.3%
86.5%
Q2 25
74.5%
86.3%
Q1 25
61.8%
86.9%
Q4 24
62.1%
85.5%
Q3 24
63.6%
85.8%
Q2 24
63.5%
85.9%
Operating Margin
GPN
GPN
VRTX
VRTX
Q1 26
12.5%
38.1%
Q4 25
5.9%
37.8%
Q3 25
38.8%
38.6%
Q2 25
21.8%
38.8%
Q1 25
19.5%
22.7%
Q4 24
33.1%
35.2%
Q3 24
18.3%
40.3%
Q2 24
22.3%
-132.9%
Net Margin
GPN
GPN
VRTX
VRTX
Q1 26
-59.9%
34.5%
Q4 25
16.4%
37.3%
Q3 25
31.6%
35.2%
Q2 25
12.3%
34.8%
Q1 25
12.7%
23.3%
Q4 24
22.5%
31.4%
Q3 24
12.1%
37.7%
Q2 24
14.6%
-135.8%
EPS (diluted)
GPN
GPN
VRTX
VRTX
Q1 26
$-6.59
$4.02
Q4 25
$0.91
$4.64
Q3 25
$2.64
$4.20
Q2 25
$0.99
$3.99
Q1 25
$1.24
$2.49
Q4 24
$2.23
$3.62
Q3 24
$1.24
$4.01
Q2 24
$1.47
$-13.92

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
GPN
GPN
VRTX
VRTX
Cash + ST InvestmentsLiquidity on hand
$5.9B
Total DebtLower is stronger
$22.6B
Stockholders' EquityBook value
$24.5B
$19.4B
Total Assets
$64.3B
$26.5B
Debt / EquityLower = less leverage
0.92×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
GPN
GPN
VRTX
VRTX
Q1 26
$5.9B
Q4 25
$8.3B
$6.6B
Q3 25
$2.6B
$6.3B
Q2 25
$2.6B
$6.4B
Q1 25
$2.9B
$6.2B
Q4 24
$2.5B
$6.1B
Q3 24
$2.9B
$6.5B
Q2 24
$2.1B
$5.8B
Total Debt
GPN
GPN
VRTX
VRTX
Q1 26
$22.6B
Q4 25
$19.5B
Q3 25
$13.3B
Q2 25
$14.2B
Q1 25
$15.0B
Q4 24
$15.2B
Q3 24
$15.2B
Q2 24
$15.6B
Stockholders' Equity
GPN
GPN
VRTX
VRTX
Q1 26
$24.5B
$19.4B
Q4 25
$22.9B
$18.7B
Q3 25
$22.7B
$17.3B
Q2 25
$22.6B
$17.2B
Q1 25
$22.2B
$16.5B
Q4 24
$22.3B
$16.4B
Q3 24
$22.8B
$15.6B
Q2 24
$22.4B
$14.8B
Total Assets
GPN
GPN
VRTX
VRTX
Q1 26
$64.3B
$26.5B
Q4 25
$53.3B
$25.6B
Q3 25
$48.0B
$24.9B
Q2 25
$48.5B
$24.0B
Q1 25
$47.6B
$22.9B
Q4 24
$46.9B
$22.5B
Q3 24
$50.0B
$22.2B
Q2 24
$50.8B
$20.1B
Debt / Equity
GPN
GPN
VRTX
VRTX
Q1 26
0.92×
Q4 25
0.85×
Q3 25
0.59×
Q2 25
0.63×
Q1 25
0.67×
Q4 24
0.68×
Q3 24
0.67×
Q2 24
0.70×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

GPN
GPN

Segment breakdown not available.

VRTX
VRTX

TRIKAFTA/KAFTRIO$2.4B79%
ALYFTREK$424.4M14%
Other$135.9M5%
CASGEVY$42.9M1%
Vertex recorded$29.0M1%

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