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Side-by-side financial comparison of GRAIL, Inc. (GRAL) and KKR Real Estate Finance Trust Inc. (KREF). Click either name above to swap in a different company.

GRAIL, Inc. is the larger business by last-quarter revenue ($43.6M vs $25.8M, roughly 1.7× KKR Real Estate Finance Trust Inc.). KKR Real Estate Finance Trust Inc. runs the higher net margin — -101.7% vs -227.5%, a 125.7% gap on every dollar of revenue. On growth, GRAIL, Inc. posted the faster year-over-year revenue change (14.0% vs -26.6%). Over the past eight quarters, GRAIL, Inc.'s revenue compounded faster (27.7% CAGR vs -18.8%).

GRAIL, Inc. is an American biotechnology company based in Menlo Park, California founded in 2015 seeking to develop an early cancer screening test for people who do not have symptoms. As a startup it was a subsidiary of Illumina, which bought it outright in 2021.

KKR Real Estate Finance Trust Inc. is a specialized real estate finance firm sponsored by global investment firm KKR. It primarily originates, acquires, and manages a portfolio of senior secured commercial real estate loans, mostly backed by high-quality institutional commercial properties across the United States, delivering stable risk-adjusted returns to investors via interest income from its diversified assets.

GRAL vs KREF — Head-to-Head

Bigger by revenue
GRAL
GRAL
1.7× larger
GRAL
$43.6M
$25.8M
KREF
Growing faster (revenue YoY)
GRAL
GRAL
+40.6% gap
GRAL
14.0%
-26.6%
KREF
Higher net margin
KREF
KREF
125.7% more per $
KREF
-101.7%
-227.5%
GRAL
Faster 2-yr revenue CAGR
GRAL
GRAL
Annualised
GRAL
27.7%
-18.8%
KREF

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
GRAL
GRAL
KREF
KREF
Revenue
$43.6M
$25.8M
Net Profit
$-99.2M
$-26.2M
Gross Margin
Operating Margin
-285.4%
-105.1%
Net Margin
-227.5%
-101.7%
Revenue YoY
14.0%
-26.6%
Net Profit YoY
-2.2%
-229.6%
EPS (diluted)
$-2.37
$-0.49

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
GRAL
GRAL
KREF
KREF
Q4 25
$43.6M
$25.8M
Q3 25
$36.2M
$25.3M
Q2 25
$35.5M
$30.2M
Q1 25
$31.8M
$31.3M
Q4 24
$38.3M
$35.1M
Q3 24
$28.7M
$37.0M
Q2 24
$32.0M
$40.4M
Q1 24
$26.7M
$39.1M
Net Profit
GRAL
GRAL
KREF
KREF
Q4 25
$-99.2M
$-26.2M
Q3 25
$-89.0M
$13.8M
Q2 25
$-114.0M
$-29.7M
Q1 25
$-106.2M
$-4.9M
Q4 24
$-97.1M
$20.3M
Q3 24
$-125.7M
$-7.4M
Q2 24
$-1.6B
$25.8M
Q1 24
$-218.9M
$-3.1M
Operating Margin
GRAL
GRAL
KREF
KREF
Q4 25
-285.4%
-105.1%
Q3 25
-346.2%
50.4%
Q2 25
-446.9%
-101.3%
Q1 25
-482.5%
-18.3%
Q4 24
-358.0%
55.8%
Q3 24
-640.5%
-19.6%
Q2 24
-5133.8%
63.3%
Q1 24
-851.1%
-8.7%
Net Margin
GRAL
GRAL
KREF
KREF
Q4 25
-227.5%
-101.7%
Q3 25
-245.8%
54.4%
Q2 25
-320.7%
-98.5%
Q1 25
-333.6%
-15.5%
Q4 24
-253.8%
57.7%
Q3 24
-438.7%
-20.0%
Q2 24
-4958.8%
63.9%
Q1 24
-819.3%
-7.9%
EPS (diluted)
GRAL
GRAL
KREF
KREF
Q4 25
$-2.37
$-0.49
Q3 25
$-2.46
$0.12
Q2 25
$-3.18
$-0.53
Q1 25
$-3.10
$-0.15
Q4 24
$-1.49
$0.22
Q3 24
$-3.94
$-0.19
Q2 24
$-51.06
$0.29
Q1 24
$-7.05
$-0.13

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
GRAL
GRAL
KREF
KREF
Cash + ST InvestmentsLiquidity on hand
$249.7M
$84.6M
Total DebtLower is stronger
Stockholders' EquityBook value
$2.6B
$1.2B
Total Assets
$2.9B
$6.5B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
GRAL
GRAL
KREF
KREF
Q4 25
$249.7M
$84.6M
Q3 25
$126.9M
$204.1M
Q2 25
$127.4M
$107.7M
Q1 25
$133.9M
$106.4M
Q4 24
$214.2M
$104.9M
Q3 24
$853.6M
$108.8M
Q2 24
$958.8M
$107.2M
Q1 24
$199.7M
$106.5M
Stockholders' Equity
GRAL
GRAL
KREF
KREF
Q4 25
$2.6B
$1.2B
Q3 25
$2.2B
$1.2B
Q2 25
$2.3B
$1.2B
Q1 25
$2.4B
$1.3B
Q4 24
$2.5B
$1.3B
Q3 24
$2.6B
$1.4B
Q2 24
$2.7B
$1.4B
Q1 24
$1.4B
Total Assets
GRAL
GRAL
KREF
KREF
Q4 25
$2.9B
$6.5B
Q3 25
$2.6B
$6.5B
Q2 25
$2.7B
$6.8B
Q1 25
$2.8B
$6.6B
Q4 24
$3.0B
$6.4B
Q3 24
$3.1B
$6.8B
Q2 24
$3.3B
$7.1B
Q1 24
$7.3B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
GRAL
GRAL
KREF
KREF
Operating Cash FlowLast quarter
$-63.8M
$72.3M
Free Cash FlowOCF − Capex
$-63.9M
FCF MarginFCF / Revenue
-146.5%
Capex IntensityCapex / Revenue
0.2%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-299.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
GRAL
GRAL
KREF
KREF
Q4 25
$-63.8M
$72.3M
Q3 25
$-63.2M
$18.5M
Q2 25
$-77.0M
$21.1M
Q1 25
$-95.0M
$15.9M
Q4 24
$132.6M
Q3 24
$-104.6M
$49.1M
Q2 24
$-171.8M
$30.6M
Q1 24
$-207.3M
$34.5M
Free Cash Flow
GRAL
GRAL
KREF
KREF
Q4 25
$-63.9M
Q3 25
$-63.6M
Q2 25
$-77.3M
Q1 25
$-95.1M
Q4 24
Q3 24
$-105.6M
Q2 24
$-173.2M
Q1 24
$-209.8M
FCF Margin
GRAL
GRAL
KREF
KREF
Q4 25
-146.5%
Q3 25
-175.8%
Q2 25
-217.6%
Q1 25
-298.6%
Q4 24
Q3 24
-368.4%
Q2 24
-541.7%
Q1 24
-785.3%
Capex Intensity
GRAL
GRAL
KREF
KREF
Q4 25
0.2%
Q3 25
1.1%
Q2 25
1.0%
Q1 25
0.2%
Q4 24
Q3 24
3.4%
Q2 24
4.3%
Q1 24
9.5%
Cash Conversion
GRAL
GRAL
KREF
KREF
Q4 25
Q3 25
1.34×
Q2 25
Q1 25
Q4 24
6.54×
Q3 24
Q2 24
1.19×
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

GRAL
GRAL

Screening Revenue$42.3M97%
Developmental Services Revenue$1.3M3%

KREF
KREF

Segment breakdown not available.

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