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Side-by-side financial comparison of GRAIL, Inc. (GRAL) and OCTAVE SPECIALTY GROUP INC (OSG). Click either name above to swap in a different company.

OCTAVE SPECIALTY GROUP INC is the larger business by last-quarter revenue ($66.9M vs $43.6M, roughly 1.5× GRAIL, Inc.). OCTAVE SPECIALTY GROUP INC runs the higher net margin — -73.8% vs -227.5%, a 153.7% gap on every dollar of revenue. On growth, GRAIL, Inc. posted the faster year-over-year revenue change (14.0% vs 2.6%). Over the past eight quarters, GRAIL, Inc.'s revenue compounded faster (27.7% CAGR vs 16.2%).

GRAIL, Inc. is an American biotechnology company based in Menlo Park, California founded in 2015 seeking to develop an early cancer screening test for people who do not have symptoms. As a startup it was a subsidiary of Illumina, which bought it outright in 2021.

Octave Specialty Group Inc. is a specialty insurance holding company that provides tailored property and casualty insurance products. Its core business focuses on excess and surplus lines, catering to commercial and individual clients across primary North American markets with customized risk coverage solutions.

GRAL vs OSG — Head-to-Head

Bigger by revenue
OSG
OSG
1.5× larger
OSG
$66.9M
$43.6M
GRAL
Growing faster (revenue YoY)
GRAL
GRAL
+11.4% gap
GRAL
14.0%
2.6%
OSG
Higher net margin
OSG
OSG
153.7% more per $
OSG
-73.8%
-227.5%
GRAL
Faster 2-yr revenue CAGR
GRAL
GRAL
Annualised
GRAL
27.7%
16.2%
OSG

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
GRAL
GRAL
OSG
OSG
Revenue
$43.6M
$66.9M
Net Profit
$-99.2M
$-29.7M
Gross Margin
Operating Margin
-285.4%
-76.7%
Net Margin
-227.5%
-73.8%
Revenue YoY
14.0%
2.6%
Net Profit YoY
-2.2%
-41.7%
EPS (diluted)
$-2.37
$-0.82

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
GRAL
GRAL
OSG
OSG
Q4 25
$43.6M
$66.9M
Q3 25
$36.2M
$66.6M
Q2 25
$35.5M
$55.0M
Q1 25
$31.8M
$62.8M
Q4 24
$38.3M
$65.2M
Q3 24
$28.7M
$70.0M
Q2 24
$32.0M
$51.0M
Q1 24
$26.7M
$49.6M
Net Profit
GRAL
GRAL
OSG
OSG
Q4 25
$-99.2M
$-29.7M
Q3 25
$-89.0M
$-112.6M
Q2 25
$-114.0M
$-72.7M
Q1 25
$-106.2M
$-44.7M
Q4 24
$-97.1M
$-20.9M
Q3 24
$-125.7M
$-27.5M
Q2 24
$-1.6B
$-750.0K
Q1 24
$-218.9M
$20.8M
Operating Margin
GRAL
GRAL
OSG
OSG
Q4 25
-285.4%
-76.7%
Q3 25
-346.2%
-48.2%
Q2 25
-446.9%
-41.8%
Q1 25
-482.5%
-24.1%
Q4 24
-358.0%
-55.5%
Q3 24
-640.5%
-29.7%
Q2 24
-5133.8%
-28.9%
Q1 24
-851.1%
-6.5%
Net Margin
GRAL
GRAL
OSG
OSG
Q4 25
-227.5%
-73.8%
Q3 25
-245.8%
-169.1%
Q2 25
-320.7%
-132.3%
Q1 25
-333.6%
-71.3%
Q4 24
-253.8%
-55.1%
Q3 24
-438.7%
-39.3%
Q2 24
-4958.8%
-1.5%
Q1 24
-819.3%
41.9%
EPS (diluted)
GRAL
GRAL
OSG
OSG
Q4 25
$-2.37
$-0.82
Q3 25
$-2.46
$-2.35
Q2 25
$-3.18
$-1.54
Q1 25
$-3.10
$-1.22
Q4 24
$-1.49
$-11.75
Q3 24
$-3.94
$-0.63
Q2 24
$-51.06
$-0.02
Q1 24
$-7.05
$0.44

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
GRAL
GRAL
OSG
OSG
Cash + ST InvestmentsLiquidity on hand
$249.7M
$146.4M
Total DebtLower is stronger
$117.6M
Stockholders' EquityBook value
$2.6B
$715.8M
Total Assets
$2.9B
$2.2B
Debt / EquityLower = less leverage
0.16×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
GRAL
GRAL
OSG
OSG
Q4 25
$249.7M
$146.4M
Q3 25
$126.9M
$27.5M
Q2 25
$127.4M
$22.5M
Q1 25
$133.9M
$34.1M
Q4 24
$214.2M
$157.2M
Q3 24
$853.6M
$40.8M
Q2 24
$958.8M
$14.6M
Q1 24
$199.7M
$13.8M
Total Debt
GRAL
GRAL
OSG
OSG
Q4 25
$117.6M
Q3 25
Q2 25
Q1 25
Q4 24
$0
Q3 24
$518.0M
Q2 24
$515.0M
Q1 24
$512.0M
Stockholders' Equity
GRAL
GRAL
OSG
OSG
Q4 25
$2.6B
$715.8M
Q3 25
$2.2B
$843.4M
Q2 25
$2.3B
$859.8M
Q1 25
$2.4B
$852.2M
Q4 24
$2.5B
$798.4M
Q3 24
$2.6B
$1.5B
Q2 24
$2.7B
$1.4B
Q1 24
$1.4B
Total Assets
GRAL
GRAL
OSG
OSG
Q4 25
$2.9B
$2.2B
Q3 25
$2.6B
$2.1B
Q2 25
$2.7B
$8.5B
Q1 25
$2.8B
$8.3B
Q4 24
$3.0B
$8.1B
Q3 24
$3.1B
$9.3B
Q2 24
$3.3B
$8.2B
Q1 24
$8.4B
Debt / Equity
GRAL
GRAL
OSG
OSG
Q4 25
0.16×
Q3 25
Q2 25
Q1 25
Q4 24
0.00×
Q3 24
0.35×
Q2 24
0.38×
Q1 24
0.38×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
GRAL
GRAL
OSG
OSG
Operating Cash FlowLast quarter
$-63.8M
$-52.3M
Free Cash FlowOCF − Capex
$-63.9M
FCF MarginFCF / Revenue
-146.5%
Capex IntensityCapex / Revenue
0.2%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-299.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
GRAL
GRAL
OSG
OSG
Q4 25
$-63.8M
$-52.3M
Q3 25
$-63.2M
$-41.2M
Q2 25
$-77.0M
$2.1M
Q1 25
$-95.0M
$-12.6M
Q4 24
$762.0K
Q3 24
$-104.6M
$48.9M
Q2 24
$-171.8M
$20.4M
Q1 24
$-207.3M
$7.1M
Free Cash Flow
GRAL
GRAL
OSG
OSG
Q4 25
$-63.9M
Q3 25
$-63.6M
Q2 25
$-77.3M
Q1 25
$-95.1M
Q4 24
Q3 24
$-105.6M
Q2 24
$-173.2M
Q1 24
$-209.8M
FCF Margin
GRAL
GRAL
OSG
OSG
Q4 25
-146.5%
Q3 25
-175.8%
Q2 25
-217.6%
Q1 25
-298.6%
Q4 24
Q3 24
-368.4%
Q2 24
-541.7%
Q1 24
-785.3%
Capex Intensity
GRAL
GRAL
OSG
OSG
Q4 25
0.2%
Q3 25
1.1%
Q2 25
1.0%
Q1 25
0.2%
Q4 24
Q3 24
3.4%
Q2 24
4.3%
Q1 24
9.5%
Cash Conversion
GRAL
GRAL
OSG
OSG
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
0.34×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

GRAL
GRAL

Screening Revenue$42.3M97%
Developmental Services Revenue$1.3M3%

OSG
OSG

Other$28.7M43%
Specialty Property Casualty Program$23.1M34%
Accident Health$9.6M14%
Specialty Automobile$3.1M5%
Niche Specialty Risks$2.4M4%

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