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Side-by-side financial comparison of GRAIL, Inc. (GRAL) and Spok Holdings, Inc (SPOK). Click either name above to swap in a different company.

GRAIL, Inc. is the larger business by last-quarter revenue ($43.6M vs $33.9M, roughly 1.3× Spok Holdings, Inc). Spok Holdings, Inc runs the higher net margin — 8.7% vs -227.5%, a 236.1% gap on every dollar of revenue. On growth, GRAIL, Inc. posted the faster year-over-year revenue change (14.0% vs -0.1%). Spok Holdings, Inc produced more free cash flow last quarter ($10.1M vs $-63.9M). Over the past eight quarters, GRAIL, Inc.'s revenue compounded faster (27.7% CAGR vs -1.5%).

GRAIL, Inc. is an American biotechnology company based in Menlo Park, California founded in 2015 seeking to develop an early cancer screening test for people who do not have symptoms. As a startup it was a subsidiary of Illumina, which bought it outright in 2021.

Spok Holdings, Inc. is a global provider of critical communication solutions primarily serving the healthcare industry. It offers unified clinical communication platforms, secure messaging tools, alerting systems, and on-call scheduling software that help care teams coordinate efficiently, cut response times, and boost patient safety across medical facilities.

GRAL vs SPOK — Head-to-Head

Bigger by revenue
GRAL
GRAL
1.3× larger
GRAL
$43.6M
$33.9M
SPOK
Growing faster (revenue YoY)
GRAL
GRAL
+14.1% gap
GRAL
14.0%
-0.1%
SPOK
Higher net margin
SPOK
SPOK
236.1% more per $
SPOK
8.7%
-227.5%
GRAL
More free cash flow
SPOK
SPOK
$74.0M more FCF
SPOK
$10.1M
$-63.9M
GRAL
Faster 2-yr revenue CAGR
GRAL
GRAL
Annualised
GRAL
27.7%
-1.5%
SPOK

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
GRAL
GRAL
SPOK
SPOK
Revenue
$43.6M
$33.9M
Net Profit
$-99.2M
$2.9M
Gross Margin
76.7%
Operating Margin
-285.4%
11.6%
Net Margin
-227.5%
8.7%
Revenue YoY
14.0%
-0.1%
Net Profit YoY
-2.2%
-19.6%
EPS (diluted)
$-2.37
$0.13

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
GRAL
GRAL
SPOK
SPOK
Q4 25
$43.6M
$33.9M
Q3 25
$36.2M
$33.9M
Q2 25
$35.5M
$35.7M
Q1 25
$31.8M
$36.3M
Q4 24
$38.3M
$33.9M
Q3 24
$28.7M
$34.9M
Q2 24
$32.0M
$34.0M
Q1 24
$26.7M
$34.9M
Net Profit
GRAL
GRAL
SPOK
SPOK
Q4 25
$-99.2M
$2.9M
Q3 25
$-89.0M
$3.2M
Q2 25
$-114.0M
$4.6M
Q1 25
$-106.2M
$5.2M
Q4 24
$-97.1M
$3.6M
Q3 24
$-125.7M
$3.7M
Q2 24
$-1.6B
$3.4M
Q1 24
$-218.9M
$4.2M
Gross Margin
GRAL
GRAL
SPOK
SPOK
Q4 25
76.7%
Q3 25
78.3%
Q2 25
79.5%
Q1 25
80.1%
Q4 24
78.5%
Q3 24
79.5%
Q2 24
78.9%
Q1 24
79.5%
Operating Margin
GRAL
GRAL
SPOK
SPOK
Q4 25
-285.4%
11.6%
Q3 25
-346.2%
12.9%
Q2 25
-446.9%
15.1%
Q1 25
-482.5%
16.6%
Q4 24
-358.0%
13.7%
Q3 24
-640.5%
14.2%
Q2 24
-5133.8%
13.2%
Q1 24
-851.1%
14.0%
Net Margin
GRAL
GRAL
SPOK
SPOK
Q4 25
-227.5%
8.7%
Q3 25
-245.8%
9.5%
Q2 25
-320.7%
12.8%
Q1 25
-333.6%
14.3%
Q4 24
-253.8%
10.8%
Q3 24
-438.7%
10.5%
Q2 24
-4958.8%
10.1%
Q1 24
-819.3%
12.1%
EPS (diluted)
GRAL
GRAL
SPOK
SPOK
Q4 25
$-2.37
$0.13
Q3 25
$-2.46
$0.15
Q2 25
$-3.18
$0.22
Q1 25
$-3.10
$0.25
Q4 24
$-1.49
$0.17
Q3 24
$-3.94
$0.18
Q2 24
$-51.06
$0.17
Q1 24
$-7.05
$0.21

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
GRAL
GRAL
SPOK
SPOK
Cash + ST InvestmentsLiquidity on hand
$249.7M
$25.3M
Total DebtLower is stronger
Stockholders' EquityBook value
$2.6B
$146.4M
Total Assets
$2.9B
$206.1M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
GRAL
GRAL
SPOK
SPOK
Q4 25
$249.7M
$25.3M
Q3 25
$126.9M
$21.4M
Q2 25
$127.4M
$20.2M
Q1 25
$133.9M
$19.9M
Q4 24
$214.2M
$29.1M
Q3 24
$853.6M
$27.8M
Q2 24
$958.8M
$23.9M
Q1 24
$199.7M
$23.3M
Stockholders' Equity
GRAL
GRAL
SPOK
SPOK
Q4 25
$2.6B
$146.4M
Q3 25
$2.2B
$148.7M
Q2 25
$2.3B
$150.9M
Q1 25
$2.4B
$151.7M
Q4 24
$2.5B
$154.7M
Q3 24
$2.6B
$156.3M
Q2 24
$2.7B
$158.2M
Q1 24
$160.2M
Total Assets
GRAL
GRAL
SPOK
SPOK
Q4 25
$2.9B
$206.1M
Q3 25
$2.6B
$209.7M
Q2 25
$2.7B
$208.7M
Q1 25
$2.8B
$204.5M
Q4 24
$3.0B
$217.1M
Q3 24
$3.1B
$216.8M
Q2 24
$3.3B
$216.4M
Q1 24
$215.0M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
GRAL
GRAL
SPOK
SPOK
Operating Cash FlowLast quarter
$-63.8M
$11.5M
Free Cash FlowOCF − Capex
$-63.9M
$10.1M
FCF MarginFCF / Revenue
-146.5%
29.9%
Capex IntensityCapex / Revenue
0.2%
4.1%
Cash ConversionOCF / Net Profit
3.93×
TTM Free Cash FlowTrailing 4 quarters
$-299.9M
$25.2M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
GRAL
GRAL
SPOK
SPOK
Q4 25
$-63.8M
$11.5M
Q3 25
$-63.2M
$8.1M
Q2 25
$-77.0M
$7.0M
Q1 25
$-95.0M
$2.3M
Q4 24
$8.4M
Q3 24
$-104.6M
$11.1M
Q2 24
$-171.8M
$7.4M
Q1 24
$-207.3M
$2.0M
Free Cash Flow
GRAL
GRAL
SPOK
SPOK
Q4 25
$-63.9M
$10.1M
Q3 25
$-63.6M
$7.6M
Q2 25
$-77.3M
$6.0M
Q1 25
$-95.1M
$1.5M
Q4 24
$7.5M
Q3 24
$-105.6M
$10.3M
Q2 24
$-173.2M
$6.8M
Q1 24
$-209.8M
$1.1M
FCF Margin
GRAL
GRAL
SPOK
SPOK
Q4 25
-146.5%
29.9%
Q3 25
-175.8%
22.4%
Q2 25
-217.6%
16.8%
Q1 25
-298.6%
4.2%
Q4 24
22.3%
Q3 24
-368.4%
29.4%
Q2 24
-541.7%
20.0%
Q1 24
-785.3%
3.2%
Capex Intensity
GRAL
GRAL
SPOK
SPOK
Q4 25
0.2%
4.1%
Q3 25
1.1%
1.6%
Q2 25
1.0%
2.9%
Q1 25
0.2%
2.1%
Q4 24
2.5%
Q3 24
3.4%
2.4%
Q2 24
4.3%
1.9%
Q1 24
9.5%
2.5%
Cash Conversion
GRAL
GRAL
SPOK
SPOK
Q4 25
3.93×
Q3 25
2.54×
Q2 25
1.55×
Q1 25
0.43×
Q4 24
2.31×
Q3 24
3.03×
Q2 24
2.17×
Q1 24
0.47×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

GRAL
GRAL

Screening Revenue$42.3M97%
Developmental Services Revenue$1.3M3%

SPOK
SPOK

Paging$16.8M50%
Software Operations$16.0M47%
License$1.2M4%

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