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Side-by-side financial comparison of GYRE THERAPEUTICS, INC. (GYRE) and HERC HOLDINGS INC (HRI). Click either name above to swap in a different company.
GYRE THERAPEUTICS, INC. is the larger business by last-quarter revenue ($37.2M vs $30.1M, roughly 1.2× HERC HOLDINGS INC). GYRE THERAPEUTICS, INC. runs the higher net margin — -3.7% vs -331.7%, a 328.0% gap on every dollar of revenue. On growth, HERC HOLDINGS INC posted the faster year-over-year revenue change (629.3% vs 33.4%). GYRE THERAPEUTICS, INC. produced more free cash flow last quarter ($-5.8M vs $-14.3M).
GYRE Therapeutics, Inc. is a clinical-stage biopharmaceutical company dedicated to developing novel targeted therapies for hard-to-treat hematologic malignancies and solid tumors. It focuses on precision oncology to address unmet patient needs, with operations primarily based in North America.
Herc Holdings Inc. is a leading North American equipment rental service provider. It offers rental assets including heavy construction machinery, power tools, temporary power and climate control systems, serving clients across construction, industrial, events, infrastructure and government segments, with operations across the U.S. and Canada.
GYRE vs HRI — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $37.2M | $30.1M |
| Net Profit | $-1.4M | $-99.9M |
| Gross Margin | 95.3% | 42.3% |
| Operating Margin | 0.3% | -77.4% |
| Net Margin | -3.7% | -331.7% |
| Revenue YoY | 33.4% | 629.3% |
| Net Profit YoY | -340.1% | -866.2% |
| EPS (diluted) | $-0.01 | $-0.36 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $37.2M | $30.1M | ||
| Q3 25 | $30.6M | $10.1M | ||
| Q2 25 | $26.8M | $6.3M | ||
| Q1 25 | $22.1M | $4.2M | ||
| Q4 24 | $27.9M | $4.1M | ||
| Q3 24 | $25.5M | — | ||
| Q2 24 | $25.2M | — | ||
| Q1 24 | $27.2M | — |
| Q4 25 | $-1.4M | $-99.9M | ||
| Q3 25 | $5.9M | $-7.5M | ||
| Q2 25 | $1.6M | $-10.8M | ||
| Q1 25 | $3.7M | $-14.1M | ||
| Q4 24 | $569.0K | $-10.3M | ||
| Q3 24 | $2.9M | — | ||
| Q2 24 | $4.5M | — | ||
| Q1 24 | $9.9M | — |
| Q4 25 | 95.3% | 42.3% | ||
| Q3 25 | 94.7% | 25.8% | ||
| Q2 25 | 95.7% | 53.1% | ||
| Q1 25 | 95.9% | 35.0% | ||
| Q4 24 | 95.8% | 21.4% | ||
| Q3 24 | 96.2% | — | ||
| Q2 24 | 96.9% | — | ||
| Q1 24 | 96.4% | — |
| Q4 25 | 0.3% | -77.4% | ||
| Q3 25 | 22.7% | -153.5% | ||
| Q2 25 | 8.1% | -147.4% | ||
| Q1 25 | 10.3% | -242.7% | ||
| Q4 24 | 2.4% | -206.3% | ||
| Q3 24 | 16.6% | — | ||
| Q2 24 | 12.7% | — | ||
| Q1 24 | 29.7% | — |
| Q4 25 | -3.7% | -331.7% | ||
| Q3 25 | 19.4% | -74.1% | ||
| Q2 25 | 5.9% | -171.4% | ||
| Q1 25 | 16.9% | -332.8% | ||
| Q4 24 | 2.0% | -250.3% | ||
| Q3 24 | 11.2% | — | ||
| Q2 24 | 18.0% | — | ||
| Q1 24 | 36.6% | — |
| Q4 25 | $-0.01 | $-0.36 | ||
| Q3 25 | $0.03 | $-0.03 | ||
| Q2 25 | $0.00 | $-0.08 | ||
| Q1 25 | $0.00 | $-0.15 | ||
| Q4 24 | $0.00 | $-0.15 | ||
| Q3 24 | $0.01 | — | ||
| Q2 24 | $0.01 | — | ||
| Q1 24 | $0.03 | — |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $52.4M | $550.7M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $106.0M | $437.8M |
| Total Assets | $166.1M | $1.1B |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $52.4M | $550.7M | ||
| Q3 25 | $60.0M | $432.8M | ||
| Q2 25 | $54.4M | $67.6M | ||
| Q1 25 | $29.9M | — | ||
| Q4 24 | $26.7M | $30.0M | ||
| Q3 24 | $25.1M | — | ||
| Q2 24 | $25.1M | — | ||
| Q1 24 | $37.4M | — |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | $300.0K | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
| Q4 25 | $106.0M | $437.8M | ||
| Q3 25 | $101.9M | $486.1M | ||
| Q2 25 | $92.0M | $90.8M | ||
| Q1 25 | $68.1M | $26.1M | ||
| Q4 24 | $63.3M | $16.6M | ||
| Q3 24 | $63.2M | — | ||
| Q2 24 | $60.4M | — | ||
| Q1 24 | $56.6M | — |
| Q4 25 | $166.1M | $1.1B | ||
| Q3 25 | $159.4M | $550.2M | ||
| Q2 25 | $152.6M | $152.0M | ||
| Q1 25 | $129.8M | $104.6M | ||
| Q4 24 | $125.4M | $109.6M | ||
| Q3 24 | $125.2M | — | ||
| Q2 24 | $120.9M | — | ||
| Q1 24 | $122.0M | — |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | 0.02× | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-5.6M | $-12.7M |
| Free Cash FlowOCF − Capex | $-5.8M | $-14.3M |
| FCF MarginFCF / Revenue | -15.5% | -47.6% |
| Capex IntensityCapex / Revenue | 0.4% | 5.3% |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $-180.0K | $-40.8M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-5.6M | $-12.7M | ||
| Q3 25 | $4.7M | $-11.0M | ||
| Q2 25 | $2.1M | $-8.4M | ||
| Q1 25 | $-129.0K | $-6.7M | ||
| Q4 24 | $-2.8M | $-8.1M | ||
| Q3 24 | $1.7M | — | ||
| Q2 24 | $-5.5M | — | ||
| Q1 24 | $2.9M | — |
| Q4 25 | $-5.8M | $-14.3M | ||
| Q3 25 | $4.0M | $-11.1M | ||
| Q2 25 | $1.8M | $-8.5M | ||
| Q1 25 | $-251.0K | $-6.8M | ||
| Q4 24 | $-2.8M | $-8.1M | ||
| Q3 24 | $1.0M | — | ||
| Q2 24 | $-6.9M | — | ||
| Q1 24 | $2.7M | — |
| Q4 25 | -15.5% | -47.6% | ||
| Q3 25 | 13.1% | -110.2% | ||
| Q2 25 | 6.8% | -135.5% | ||
| Q1 25 | -1.1% | -160.8% | ||
| Q4 24 | -10.1% | -197.1% | ||
| Q3 24 | 4.1% | — | ||
| Q2 24 | -27.5% | — | ||
| Q1 24 | 9.8% | — |
| Q4 25 | 0.4% | 5.3% | ||
| Q3 25 | 2.2% | 1.7% | ||
| Q2 25 | 1.0% | 1.5% | ||
| Q1 25 | 0.6% | 4.0% | ||
| Q4 24 | 0.2% | 0.7% | ||
| Q3 24 | 2.7% | — | ||
| Q2 24 | 5.8% | — | ||
| Q1 24 | 0.9% | — |
| Q4 25 | — | — | ||
| Q3 25 | 0.79× | — | ||
| Q2 25 | 1.32× | — | ||
| Q1 25 | -0.03× | — | ||
| Q4 24 | -4.85× | — | ||
| Q3 24 | 0.60× | — | ||
| Q2 24 | -1.21× | — | ||
| Q1 24 | 0.29× | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
GYRE
Segment breakdown not available.
HRI
| Sales Of New Equipment | $9.0M | 30% |
| Sales Of Parts And Supplies | $8.0M | 27% |
| Other | $7.1M | 24% |
| Serviceand Other Revenue | $6.0M | 20% |
