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Side-by-side financial comparison of GYRE THERAPEUTICS, INC. (GYRE) and Orchid Island Capital, Inc. (ORC). Click either name above to swap in a different company.

Orchid Island Capital, Inc. is the larger business by last-quarter revenue ($38.5M vs $37.2M, roughly 1.0× GYRE THERAPEUTICS, INC.). Orchid Island Capital, Inc. runs the higher net margin — 268.7% vs -3.7%, a 272.4% gap on every dollar of revenue. On growth, Orchid Island Capital, Inc. posted the faster year-over-year revenue change (372.6% vs 33.4%). Over the past eight quarters, Orchid Island Capital, Inc.'s revenue compounded faster (301.6% CAGR vs 17.0%).

GYRE Therapeutics, Inc. is a clinical-stage biopharmaceutical company dedicated to developing novel targeted therapies for hard-to-treat hematologic malignancies and solid tumors. It focuses on precision oncology to address unmet patient needs, with operations primarily based in North America.

Orchid Island Capital, Inc. is a U.S.-based specialty finance company operating as a real estate investment trust. It primarily invests in residential mortgage-backed securities, including agency and non-agency products, targeting consistent risk-adjusted returns for its investors across U.S. fixed income markets.

GYRE vs ORC — Head-to-Head

Bigger by revenue
ORC
ORC
1.0× larger
ORC
$38.5M
$37.2M
GYRE
Growing faster (revenue YoY)
ORC
ORC
+339.1% gap
ORC
372.6%
33.4%
GYRE
Higher net margin
ORC
ORC
272.4% more per $
ORC
268.7%
-3.7%
GYRE
Faster 2-yr revenue CAGR
ORC
ORC
Annualised
ORC
301.6%
17.0%
GYRE

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
GYRE
GYRE
ORC
ORC
Revenue
$37.2M
$38.5M
Net Profit
$-1.4M
$103.4M
Gross Margin
95.3%
Operating Margin
0.3%
Net Margin
-3.7%
268.7%
Revenue YoY
33.4%
372.6%
Net Profit YoY
-340.1%
1764.9%
EPS (diluted)
$-0.01

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
GYRE
GYRE
ORC
ORC
Q4 25
$37.2M
$38.5M
Q3 25
$30.6M
$26.9M
Q2 25
$26.8M
$23.2M
Q1 25
$22.1M
$19.7M
Q4 24
$27.9M
Q3 24
$25.5M
$340.0K
Q2 24
$25.2M
$-697.0K
Q1 24
$27.2M
$-2.5M
Net Profit
GYRE
GYRE
ORC
ORC
Q4 25
$-1.4M
$103.4M
Q3 25
$5.9M
$72.1M
Q2 25
$1.6M
$-33.6M
Q1 25
$3.7M
$17.1M
Q4 24
$569.0K
Q3 24
$2.9M
$17.3M
Q2 24
$4.5M
$-5.0M
Q1 24
$9.9M
$19.8M
Gross Margin
GYRE
GYRE
ORC
ORC
Q4 25
95.3%
Q3 25
94.7%
Q2 25
95.7%
Q1 25
95.9%
Q4 24
95.8%
Q3 24
96.2%
Q2 24
96.9%
Q1 24
96.4%
Operating Margin
GYRE
GYRE
ORC
ORC
Q4 25
0.3%
Q3 25
22.7%
Q2 25
8.1%
Q1 25
10.3%
Q4 24
2.4%
Q3 24
16.6%
Q2 24
12.7%
Q1 24
29.7%
Net Margin
GYRE
GYRE
ORC
ORC
Q4 25
-3.7%
268.7%
Q3 25
19.4%
267.8%
Q2 25
5.9%
-145.0%
Q1 25
16.9%
86.9%
Q4 24
2.0%
Q3 24
11.2%
5094.1%
Q2 24
18.0%
714.3%
Q1 24
36.6%
-794.2%
EPS (diluted)
GYRE
GYRE
ORC
ORC
Q4 25
$-0.01
Q3 25
$0.03
Q2 25
$0.00
Q1 25
$0.00
Q4 24
$0.00
Q3 24
$0.01
Q2 24
$0.01
Q1 24
$0.03

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
GYRE
GYRE
ORC
ORC
Cash + ST InvestmentsLiquidity on hand
$52.4M
$665.9M
Total DebtLower is stronger
Stockholders' EquityBook value
$106.0M
$1.4B
Total Assets
$166.1M
$11.7B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
GYRE
GYRE
ORC
ORC
Q4 25
$52.4M
$665.9M
Q3 25
$60.0M
$583.9M
Q2 25
$54.4M
$440.8M
Q1 25
$29.9M
$396.4M
Q4 24
$26.7M
Q3 24
$25.1M
$322.1M
Q2 24
$25.1M
$241.0M
Q1 24
$37.4M
$190.4M
Stockholders' Equity
GYRE
GYRE
ORC
ORC
Q4 25
$106.0M
$1.4B
Q3 25
$101.9M
$1.1B
Q2 25
$92.0M
$912.0M
Q1 25
$68.1M
$855.9M
Q4 24
$63.3M
Q3 24
$63.2M
$656.0M
Q2 24
$60.4M
$555.9M
Q1 24
$56.6M
$481.6M
Total Assets
GYRE
GYRE
ORC
ORC
Q4 25
$166.1M
$11.7B
Q3 25
$159.4M
$9.1B
Q2 25
$152.6M
$7.6B
Q1 25
$129.8M
$7.3B
Q4 24
$125.4M
Q3 24
$125.2M
$5.9B
Q2 24
$120.9M
$4.9B
Q1 24
$122.0M
$4.2B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
GYRE
GYRE
ORC
ORC
Operating Cash FlowLast quarter
$-5.6M
$120.4M
Free Cash FlowOCF − Capex
$-5.8M
FCF MarginFCF / Revenue
-15.5%
Capex IntensityCapex / Revenue
0.4%
Cash ConversionOCF / Net Profit
1.16×
TTM Free Cash FlowTrailing 4 quarters
$-180.0K

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
GYRE
GYRE
ORC
ORC
Q4 25
$-5.6M
$120.4M
Q3 25
$4.7M
$28.0M
Q2 25
$2.1M
$18.4M
Q1 25
$-129.0K
$25.8M
Q4 24
$-2.8M
Q3 24
$1.7M
$-14.8M
Q2 24
$-5.5M
$19.3M
Q1 24
$2.9M
$45.0M
Free Cash Flow
GYRE
GYRE
ORC
ORC
Q4 25
$-5.8M
Q3 25
$4.0M
Q2 25
$1.8M
Q1 25
$-251.0K
Q4 24
$-2.8M
Q3 24
$1.0M
Q2 24
$-6.9M
Q1 24
$2.7M
FCF Margin
GYRE
GYRE
ORC
ORC
Q4 25
-15.5%
Q3 25
13.1%
Q2 25
6.8%
Q1 25
-1.1%
Q4 24
-10.1%
Q3 24
4.1%
Q2 24
-27.5%
Q1 24
9.8%
Capex Intensity
GYRE
GYRE
ORC
ORC
Q4 25
0.4%
Q3 25
2.2%
Q2 25
1.0%
Q1 25
0.6%
Q4 24
0.2%
Q3 24
2.7%
Q2 24
5.8%
Q1 24
0.9%
Cash Conversion
GYRE
GYRE
ORC
ORC
Q4 25
1.16×
Q3 25
0.79×
0.39×
Q2 25
1.32×
Q1 25
-0.03×
1.51×
Q4 24
-4.85×
Q3 24
0.60×
-0.86×
Q2 24
-1.21×
Q1 24
0.29×
2.28×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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