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Side-by-side financial comparison of GYRE THERAPEUTICS, INC. (GYRE) and Organogenesis Holdings Inc. (ORGO). Click either name above to swap in a different company.
Organogenesis Holdings Inc. is the larger business by last-quarter revenue ($37.2M vs $37.2M, roughly 1.0× GYRE THERAPEUTICS, INC.). On growth, GYRE THERAPEUTICS, INC. posted the faster year-over-year revenue change (33.4% vs -57.1%). Over the past eight quarters, GYRE THERAPEUTICS, INC.'s revenue compounded faster (17.0% CAGR vs -46.5%).
GYRE Therapeutics, Inc. is a clinical-stage biopharmaceutical company dedicated to developing novel targeted therapies for hard-to-treat hematologic malignancies and solid tumors. It focuses on precision oncology to address unmet patient needs, with operations primarily based in North America.
Organogenesis Holdings Inc. is a leading regenerative medicine firm specializing in developing and manufacturing advanced therapeutic products for wound care, surgical repair, sports medicine, and dermatology. It serves healthcare providers and patients primarily in the U.S. and select international markets, offering clinically validated solutions for unmet medical needs.
GYRE vs ORGO — Head-to-Head
Income Statement — Q4 FY2025 vs Q1 FY2026
| Metric | | |
|---|---|---|
| Revenue | $37.2M | $37.2M |
| Net Profit | $-1.4M | — |
| Gross Margin | 95.3% | 30.8% |
| Operating Margin | 0.3% | -185.1% |
| Net Margin | -3.7% | — |
| Revenue YoY | 33.4% | -57.1% |
| Net Profit YoY | -340.1% | — |
| EPS (diluted) | $-0.01 | — |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q1 26 | — | $37.2M | ||
| Q4 25 | $37.2M | $225.6M | ||
| Q3 25 | $30.6M | $150.9M | ||
| Q2 25 | $26.8M | $101.0M | ||
| Q1 25 | $22.1M | $86.7M | ||
| Q4 24 | $27.9M | $126.7M | ||
| Q3 24 | $25.5M | $115.2M | ||
| Q2 24 | $25.2M | $130.2M |
| Q1 26 | — | — | ||
| Q4 25 | $-1.4M | $43.7M | ||
| Q3 25 | $5.9M | $21.6M | ||
| Q2 25 | $1.6M | $-9.4M | ||
| Q1 25 | $3.7M | $-18.8M | ||
| Q4 24 | $569.0K | $7.7M | ||
| Q3 24 | $2.9M | $12.3M | ||
| Q2 24 | $4.5M | $-17.0M |
| Q1 26 | — | 30.8% | ||
| Q4 25 | 95.3% | — | ||
| Q3 25 | 94.7% | — | ||
| Q2 25 | 95.7% | — | ||
| Q1 25 | 95.9% | 72.6% | ||
| Q4 24 | 95.8% | 75.5% | ||
| Q3 24 | 96.2% | 76.7% | ||
| Q2 24 | 96.9% | 77.6% |
| Q1 26 | — | -185.1% | ||
| Q4 25 | 0.3% | 28.1% | ||
| Q3 25 | 22.7% | 13.7% | ||
| Q2 25 | 8.1% | -12.5% | ||
| Q1 25 | 10.3% | -30.9% | ||
| Q4 24 | 2.4% | 8.1% | ||
| Q3 24 | 16.6% | 5.4% | ||
| Q2 24 | 12.7% | -10.7% |
| Q1 26 | — | — | ||
| Q4 25 | -3.7% | 19.4% | ||
| Q3 25 | 19.4% | 14.3% | ||
| Q2 25 | 5.9% | -9.3% | ||
| Q1 25 | 16.9% | -21.7% | ||
| Q4 24 | 2.0% | 6.1% | ||
| Q3 24 | 11.2% | 10.7% | ||
| Q2 24 | 18.0% | -13.1% |
| Q1 26 | — | — | ||
| Q4 25 | $-0.01 | $0.31 | ||
| Q3 25 | $0.03 | $0.11 | ||
| Q2 25 | $0.00 | $-0.10 | ||
| Q1 25 | $0.00 | $-0.17 | ||
| Q4 24 | $0.00 | $0.05 | ||
| Q3 24 | $0.01 | $0.09 | ||
| Q2 24 | $0.01 | $-0.13 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $52.4M | $91.4M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $106.0M | — |
| Total Assets | $166.1M | $520.0M |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | — | $91.4M | ||
| Q4 25 | $52.4M | $93.7M | ||
| Q3 25 | $60.0M | $63.7M | ||
| Q2 25 | $54.4M | $73.1M | ||
| Q1 25 | $29.9M | $110.0M | ||
| Q4 24 | $26.7M | $135.6M | ||
| Q3 24 | $25.1M | $94.3M | ||
| Q2 24 | $25.1M | $89.9M |
| Q1 26 | — | — | ||
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | — | $62.3M | ||
| Q2 24 | — | $63.8M |
| Q1 26 | — | — | ||
| Q4 25 | $106.0M | $300.1M | ||
| Q3 25 | $101.9M | $255.1M | ||
| Q2 25 | $92.0M | $233.2M | ||
| Q1 25 | $68.1M | $242.9M | ||
| Q4 24 | $63.3M | $262.9M | ||
| Q3 24 | $63.2M | $278.5M | ||
| Q2 24 | $60.4M | $263.5M |
| Q1 26 | — | $520.0M | ||
| Q4 25 | $166.1M | $598.7M | ||
| Q3 25 | $159.4M | $509.8M | ||
| Q2 25 | $152.6M | $461.1M | ||
| Q1 25 | $129.8M | $467.4M | ||
| Q4 24 | $125.4M | $497.9M | ||
| Q3 24 | $125.2M | $446.3M | ||
| Q2 24 | $120.9M | $443.2M |
| Q1 26 | — | — | ||
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | — | 0.22× | ||
| Q2 24 | — | 0.24× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-5.6M | — |
| Free Cash FlowOCF − Capex | $-5.8M | — |
| FCF MarginFCF / Revenue | -15.5% | — |
| Capex IntensityCapex / Revenue | 0.4% | — |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $-180.0K | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | — | — | ||
| Q4 25 | $-5.6M | $39.4M | ||
| Q3 25 | $4.7M | $3.1M | ||
| Q2 25 | $2.1M | $-32.9M | ||
| Q1 25 | $-129.0K | $-19.9M | ||
| Q4 24 | $-2.8M | $10.9M | ||
| Q3 24 | $1.7M | $8.7M | ||
| Q2 24 | $-5.5M | $4.7M |
| Q1 26 | — | — | ||
| Q4 25 | $-5.8M | $34.8M | ||
| Q3 25 | $4.0M | $844.0K | ||
| Q2 25 | $1.8M | $-36.5M | ||
| Q1 25 | $-251.0K | $-23.6M | ||
| Q4 24 | $-2.8M | $7.6M | ||
| Q3 24 | $1.0M | $6.1M | ||
| Q2 24 | $-6.9M | $2.9M |
| Q1 26 | — | — | ||
| Q4 25 | -15.5% | 15.4% | ||
| Q3 25 | 13.1% | 0.6% | ||
| Q2 25 | 6.8% | -36.1% | ||
| Q1 25 | -1.1% | -27.2% | ||
| Q4 24 | -10.1% | 6.0% | ||
| Q3 24 | 4.1% | 5.3% | ||
| Q2 24 | -27.5% | 2.2% |
| Q1 26 | — | — | ||
| Q4 25 | 0.4% | 2.1% | ||
| Q3 25 | 2.2% | 1.5% | ||
| Q2 25 | 1.0% | 3.6% | ||
| Q1 25 | 0.6% | 4.2% | ||
| Q4 24 | 0.2% | 2.7% | ||
| Q3 24 | 2.7% | 2.2% | ||
| Q2 24 | 5.8% | 1.4% |
| Q1 26 | — | — | ||
| Q4 25 | — | 0.90× | ||
| Q3 25 | 0.79× | 0.14× | ||
| Q2 25 | 1.32× | — | ||
| Q1 25 | -0.03× | — | ||
| Q4 24 | -4.85× | 1.43× | ||
| Q3 24 | 0.60× | 0.71× | ||
| Q2 24 | -1.21× | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
