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Side-by-side financial comparison of H2O AMERICA (HTO) and IONIS PHARMACEUTICALS INC (IONS). Click either name above to swap in a different company.
IONIS PHARMACEUTICALS INC is the larger business by last-quarter revenue ($203.3M vs $199.4M, roughly 1.0× H2O AMERICA). H2O AMERICA runs the higher net margin — 8.1% vs -112.8%, a 121.0% gap on every dollar of revenue. On growth, H2O AMERICA posted the faster year-over-year revenue change (1.5% vs -10.3%). Over the past eight quarters, IONIS PHARMACEUTICALS INC's revenue compounded faster (30.4% CAGR vs 15.3%).
H2O Wireless is a United States-based prepaid cell phone service, that utilizes the AT&T network. It is a brand of the mobile virtual network operator (MVNO) Locus Telecommunications, a subsidiary of Telrite Holdings, Inc., since 2019. Locus was formerly a subsidiary of KDDI America corporation, starting in 2010. H2O Wireless is primarily advertised as a non-restrictive phone service for customers to bring or buy unlocked smartphones, although AT&T contract/locked phones may be accepted as well.
Ionis Pharmaceuticals, Inc. is a biotechnology company that specializes in discovering and developing antisense therapy, as well as RNA interference and CRISPR therapeutics. The company was founded in 1989 is based in Carlsbad, California. The company was previously known as Isis Pharmaceuticals until December 2015.
HTO vs IONS — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $199.4M | $203.3M |
| Net Profit | $16.2M | $-229.4M |
| Gross Margin | — | 96.1% |
| Operating Margin | 16.6% | -105.5% |
| Net Margin | 8.1% | -112.8% |
| Revenue YoY | 1.5% | -10.3% |
| Net Profit YoY | -29.2% | -119.8% |
| EPS (diluted) | $0.45 | $-1.35 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $199.4M | $203.3M | ||
| Q3 25 | $243.5M | $156.7M | ||
| Q2 25 | $197.8M | $452.0M | ||
| Q1 25 | $164.9M | $131.6M | ||
| Q4 24 | $196.5M | $226.6M | ||
| Q3 24 | $216.7M | $133.8M | ||
| Q2 24 | $173.1M | $225.3M | ||
| Q1 24 | $150.0M | $119.5M |
| Q4 25 | $16.2M | $-229.4M | ||
| Q3 25 | $45.1M | $-128.6M | ||
| Q2 25 | $24.7M | $123.6M | ||
| Q1 25 | $16.6M | $-146.9M | ||
| Q4 24 | $22.9M | $-104.3M | ||
| Q3 24 | $38.7M | $-140.5M | ||
| Q2 24 | $20.7M | $-66.3M | ||
| Q1 24 | $11.7M | $-142.8M |
| Q4 25 | — | 96.1% | ||
| Q3 25 | — | 98.5% | ||
| Q2 25 | — | 99.1% | ||
| Q1 25 | — | 98.9% | ||
| Q4 24 | — | 98.3% | ||
| Q3 24 | — | 99.2% | ||
| Q2 24 | — | 98.2% | ||
| Q1 24 | — | 98.2% |
| Q4 25 | 16.6% | -105.5% | ||
| Q3 25 | 26.5% | -102.2% | ||
| Q2 25 | 22.2% | 30.9% | ||
| Q1 25 | 21.8% | -111.6% | ||
| Q4 24 | 22.2% | -48.9% | ||
| Q3 24 | 26.9% | -111.1% | ||
| Q2 24 | 23.4% | -29.3% | ||
| Q1 24 | 18.6% | -125.1% |
| Q4 25 | 8.1% | -112.8% | ||
| Q3 25 | 18.5% | -82.1% | ||
| Q2 25 | 12.5% | 27.3% | ||
| Q1 25 | 10.0% | -111.6% | ||
| Q4 24 | 11.7% | -46.1% | ||
| Q3 24 | 17.8% | -105.0% | ||
| Q2 24 | 12.0% | -29.4% | ||
| Q1 24 | 7.8% | -119.5% |
| Q4 25 | $0.45 | $-1.35 | ||
| Q3 25 | $1.27 | $-0.80 | ||
| Q2 25 | $0.71 | $0.70 | ||
| Q1 25 | $0.49 | $-0.93 | ||
| Q4 24 | $0.70 | $-0.66 | ||
| Q3 24 | $1.17 | $-0.95 | ||
| Q2 24 | $0.64 | $-0.45 | ||
| Q1 24 | $0.36 | $-0.98 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $20.7M | $2.7B |
| Total DebtLower is stronger | $1.9B | $1.8B |
| Stockholders' EquityBook value | $1.5B | $489.1M |
| Total Assets | $5.1B | $3.5B |
| Debt / EquityLower = less leverage | 1.23× | 3.71× |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $20.7M | $2.7B | ||
| Q3 25 | $11.3M | $2.2B | ||
| Q2 25 | $19.8M | $2.3B | ||
| Q1 25 | $23.7M | $2.1B | ||
| Q4 24 | $11.1M | $2.3B | ||
| Q3 24 | $4.0M | $2.5B | ||
| Q2 24 | $22.8M | $2.1B | ||
| Q1 24 | $4.5M | $2.2B |
| Q4 25 | $1.9B | $1.8B | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | $1.7B | $1.3B | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
| Q4 25 | $1.5B | $489.1M | ||
| Q3 25 | $1.5B | $618.0M | ||
| Q2 25 | $1.5B | $631.7M | ||
| Q1 25 | $1.4B | $475.7M | ||
| Q4 24 | $1.4B | $588.4M | ||
| Q3 24 | $1.3B | $662.5M | ||
| Q2 24 | $1.3B | $263.7M | ||
| Q1 24 | $1.2B | $296.5M |
| Q4 25 | $5.1B | $3.5B | ||
| Q3 25 | $5.0B | $3.0B | ||
| Q2 25 | $4.8B | $3.0B | ||
| Q1 25 | $4.7B | $2.8B | ||
| Q4 24 | $4.7B | $3.0B | ||
| Q3 24 | $4.6B | $3.1B | ||
| Q2 24 | $4.4B | $2.7B | ||
| Q1 24 | $4.4B | $2.8B |
| Q4 25 | 1.23× | 3.71× | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | 1.26× | 2.13× | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $63.5M | $-137.7M |
| Free Cash FlowOCF − Capex | — | $-159.0M |
| FCF MarginFCF / Revenue | — | -78.2% |
| Capex IntensityCapex / Revenue | — | 10.5% |
| Cash ConversionOCF / Net Profit | 3.92× | — |
| TTM Free Cash FlowTrailing 4 quarters | — | $-320.0M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $63.5M | $-137.7M | ||
| Q3 25 | $77.3M | $-131.4M | ||
| Q2 25 | $60.8M | $151.3M | ||
| Q1 25 | $43.2M | $-150.8M | ||
| Q4 24 | $41.5M | $-116.1M | ||
| Q3 24 | $53.5M | $-115.0M | ||
| Q2 24 | $49.3M | $-119.9M | ||
| Q1 24 | $51.2M | $-149.9M |
| Q4 25 | — | $-159.0M | ||
| Q3 25 | — | $-136.7M | ||
| Q2 25 | — | $139.0M | ||
| Q1 25 | — | $-163.4M | ||
| Q4 24 | — | $-141.6M | ||
| Q3 24 | — | $-124.0M | ||
| Q2 24 | — | $-126.1M | ||
| Q1 24 | — | $-154.4M |
| Q4 25 | — | -78.2% | ||
| Q3 25 | — | -87.2% | ||
| Q2 25 | — | 30.8% | ||
| Q1 25 | — | -124.1% | ||
| Q4 24 | — | -62.5% | ||
| Q3 24 | — | -92.7% | ||
| Q2 24 | — | -56.0% | ||
| Q1 24 | — | -129.2% |
| Q4 25 | — | 10.5% | ||
| Q3 25 | — | 3.4% | ||
| Q2 25 | — | 2.7% | ||
| Q1 25 | — | 9.6% | ||
| Q4 24 | — | 11.3% | ||
| Q3 24 | — | 6.8% | ||
| Q2 24 | — | 2.8% | ||
| Q1 24 | — | 3.8% |
| Q4 25 | 3.92× | — | ||
| Q3 25 | 1.71× | — | ||
| Q2 25 | 2.47× | 1.22× | ||
| Q1 25 | 2.61× | — | ||
| Q4 24 | 1.81× | — | ||
| Q3 24 | 1.39× | — | ||
| Q2 24 | 2.38× | — | ||
| Q1 24 | 4.38× | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
HTO
| Water Utility Services | $191.0M | 96% |
| Other | $8.4M | 4% |
IONS
| Products | $58.0M | 29% |
| Spinraza Royalties | $54.0M | 27% |
| Collaborative Agreement Revenue | $52.4M | 26% |
| Wainus Royalties | $16.0M | 8% |
| Wainua Joint Development Revenue | $9.6M | 5% |
| Other Commercial | $7.6M | 4% |
| Other Royalties | $5.7M | 3% |
