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Side-by-side financial comparison of ICON PLC (ICLR) and iSpecimen Inc. (ISPC). Click either name above to swap in a different company.
ICON PLC is the larger business by last-quarter revenue ($2.0B vs $51.8K, roughly 39466.2× iSpecimen Inc.). ICON PLC runs the higher net margin — 0.1% vs -9662.2%, a 9662.3% gap on every dollar of revenue. On growth, ICON PLC posted the faster year-over-year revenue change (0.6% vs -96.5%). Over the past eight quarters, ICON PLC's revenue compounded faster (0.6% CAGR vs -85.0%).
ICON plc is an Irish headquartered multinational healthcare intelligence and clinical research organisation. As of February 2025 had approximately 41,900 employees in 55 countries.
Specimen Products is a Chicago-based manufacturer of custom guitars, tube amplifiers, and audio horn speakers led by luthier Ian Schneller. Specimen Products also offers courses in guitar and tube amplifier design, construction, and repair through their Chicago School of Guitar Making. The Specimen workshop offers repair services to the general public, making use of their collection of parts from rare and vintage manufacturers.
ICLR vs ISPC — Head-to-Head
Income Statement — Q3 2025 vs Q4 2025
| Metric | ||
|---|---|---|
| Revenue | $2.0B | $51.8K |
| Net Profit | $2.4M | $-5.0M |
| Gross Margin | — | -964.4% |
| Operating Margin | 4.2% | -5192.9% |
| Net Margin | 0.1% | -9662.2% |
| Revenue YoY | 0.6% | -96.5% |
| Net Profit YoY | -98.8% | 17.3% |
| EPS (diluted) | $0.03 | $-0.67 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | — | $51.8K | ||
| Q3 25 | $2.0B | $106.6K | ||
| Q2 25 | $2.0B | $713.1K | ||
| Q1 25 | $2.0B | $1.1M | ||
| Q4 24 | — | $1.5M | ||
| Q3 24 | $2.0B | $2.7M | ||
| Q2 24 | $2.1B | $2.9M | ||
| Q1 24 | $2.1B | $2.3M |
| Q4 25 | — | $-5.0M | ||
| Q3 25 | $2.4M | $-2.8M | ||
| Q2 25 | $183.0M | $-1.0M | ||
| Q1 25 | $154.2M | $-1.7M | ||
| Q4 24 | — | $-6.0M | ||
| Q3 24 | $197.1M | $-1.4M | ||
| Q2 24 | $146.9M | $-2.1M | ||
| Q1 24 | $187.4M | $-2.9M |
| Q4 25 | — | -964.4% | ||
| Q3 25 | — | -47.0% | ||
| Q2 25 | — | 44.4% | ||
| Q1 25 | — | 42.4% | ||
| Q4 24 | — | 13.5% | ||
| Q3 24 | — | 43.4% | ||
| Q2 24 | — | 51.9% | ||
| Q1 24 | — | 58.4% |
| Q4 25 | — | -5192.9% | ||
| Q3 25 | 4.2% | -2655.2% | ||
| Q2 25 | 10.4% | -255.4% | ||
| Q1 25 | 11.0% | -154.9% | ||
| Q4 24 | — | -395.8% | ||
| Q3 24 | 14.1% | -64.1% | ||
| Q2 24 | 10.8% | -76.2% | ||
| Q1 24 | 13.7% | -131.0% |
| Q4 25 | — | -9662.2% | ||
| Q3 25 | 0.1% | -2608.7% | ||
| Q2 25 | 9.1% | -146.9% | ||
| Q1 25 | 7.7% | -156.8% | ||
| Q4 24 | — | -409.8% | ||
| Q3 24 | 9.7% | -54.1% | ||
| Q2 24 | 6.9% | -73.6% | ||
| Q1 24 | 9.0% | -126.7% |
| Q4 25 | — | $-0.67 | ||
| Q3 25 | $0.03 | $-0.48 | ||
| Q2 25 | $2.30 | $-0.42 | ||
| Q1 25 | $1.90 | $-0.71 | ||
| Q4 24 | — | $-5.40 | ||
| Q3 24 | $2.36 | $-2.10 | ||
| Q2 24 | $1.76 | $-3.72 | ||
| Q1 24 | $2.25 | $-6.36 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | ||
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $468.9M | $6.9M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $9.3B | $3.1M |
| Total Assets | $16.5B | $9.5M |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | — | $6.9M | ||
| Q3 25 | $468.9M | — | ||
| Q2 25 | $390.4M | — | ||
| Q1 25 | $526.7M | — | ||
| Q4 24 | — | $1.9M | ||
| Q3 24 | $695.5M | $1.8M | ||
| Q2 24 | $506.6M | $2.2M | ||
| Q1 24 | $396.1M | $2.1M |
| Q4 25 | — | $3.1M | ||
| Q3 25 | $9.3B | $3.1M | ||
| Q2 25 | $9.6B | $622.0K | ||
| Q1 25 | $9.5B | $1.7M | ||
| Q4 24 | — | $3.3M | ||
| Q3 24 | $9.8B | $4.7M | ||
| Q2 24 | $9.6B | $6.1M | ||
| Q1 24 | $9.4B | $6.8M |
| Q4 25 | — | $9.5M | ||
| Q3 25 | $16.5B | $9.0M | ||
| Q2 25 | $16.6B | $6.0M | ||
| Q1 25 | $16.7B | $6.8M | ||
| Q4 24 | — | $9.4M | ||
| Q3 24 | $17.2B | $11.3M | ||
| Q2 24 | $17.0B | $11.9M | ||
| Q1 24 | $17.0B | $12.5M |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | ||
|---|---|---|
| Operating Cash FlowLast quarter | $387.6M | $-916.9K |
| Free Cash FlowOCF − Capex | $333.9M | — |
| FCF MarginFCF / Revenue | 16.3% | — |
| Capex IntensityCapex / Revenue | 2.6% | — |
| Cash ConversionOCF / Net Profit | 164.59× | — |
| TTM Free Cash FlowTrailing 4 quarters | $1.0B | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | — | $-916.9K | ||
| Q3 25 | $387.6M | $-2.0M | ||
| Q2 25 | $146.2M | $-192.2K | ||
| Q1 25 | $268.2M | $-1.1M | ||
| Q4 24 | — | $-3.6M | ||
| Q3 24 | $402.7M | $-1.1M | ||
| Q2 24 | $218.6M | $-1.5M | ||
| Q1 24 | $327.1M | $-2.1M |
| Q4 25 | — | — | ||
| Q3 25 | $333.9M | — | ||
| Q2 25 | $113.9M | — | ||
| Q1 25 | $239.3M | — | ||
| Q4 24 | — | $-3.6M | ||
| Q3 24 | $359.3M | $-1.1M | ||
| Q2 24 | $182.3M | — | ||
| Q1 24 | $299.9M | $-2.1M |
| Q4 25 | — | — | ||
| Q3 25 | 16.3% | — | ||
| Q2 25 | 5.6% | — | ||
| Q1 25 | 12.0% | — | ||
| Q4 24 | — | -242.7% | ||
| Q3 24 | 17.7% | -41.1% | ||
| Q2 24 | 8.6% | — | ||
| Q1 24 | 14.3% | -90.9% |
| Q4 25 | — | — | ||
| Q3 25 | 2.6% | 0.0% | ||
| Q2 25 | 1.6% | — | ||
| Q1 25 | 1.4% | — | ||
| Q4 24 | — | 0.5% | ||
| Q3 24 | 2.1% | 0.5% | ||
| Q2 24 | 1.7% | 0.0% | ||
| Q1 24 | 1.3% | 0.4% |
| Q4 25 | — | — | ||
| Q3 25 | 164.59× | — | ||
| Q2 25 | 0.80× | — | ||
| Q1 25 | 1.74× | — | ||
| Q4 24 | — | — | ||
| Q3 24 | 2.04× | — | ||
| Q2 24 | 1.49× | — | ||
| Q1 24 | 1.74× | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
ICLR
| Other Customers | $681.3M | 33% |
| Clients1125 | $549.4M | 27% |
| Clients15 | $503.3M | 25% |
| Clients610 | $308.8M | 15% |
ISPC
Segment breakdown not available.