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Side-by-side financial comparison of ILLUMINA, INC. (ILMN) and PTC Inc. (PTC). Click either name above to swap in a different company.

ILLUMINA, INC. is the larger business by last-quarter revenue ($1.2B vs $685.8M, roughly 1.7× PTC Inc.). ILLUMINA, INC. runs the higher net margin — 28.8% vs 24.3%, a 4.5% gap on every dollar of revenue. On growth, PTC Inc. posted the faster year-over-year revenue change (21.4% vs 5.0%). PTC Inc. produced more free cash flow last quarter ($267.4M vs $267.0M). Over the past eight quarters, PTC Inc.'s revenue compounded faster (6.6% CAGR vs -0.7%).

Illumina, Inc. is an American biotechnology company, headquartered in San Diego, California. Incorporated on April 1, 1998, Illumina develops, manufactures, and markets integrated systems for the analysis of genetic variation and biological function. The company provides a line of products and services that serves the sequencing, genotyping and gene expression, and proteomics markets, and serves more than 155 countries.

PTC Inc. is an American computer software and services company founded in 1985 and headquartered in Boston, Massachusetts. The company was a pioneer in parametric, associative feature-based, solid computer-aided design (CAD) modeling software in 1988, including an Internet-based product for Product Lifecycle Management (PLM) in 1998. PTC markets products and services and an Internet of Things (IoT) and augmented reality (AR) platform for partners and developers.

ILMN vs PTC — Head-to-Head

Bigger by revenue
ILMN
ILMN
1.7× larger
ILMN
$1.2B
$685.8M
PTC
Growing faster (revenue YoY)
PTC
PTC
+16.4% gap
PTC
21.4%
5.0%
ILMN
Higher net margin
ILMN
ILMN
4.5% more per $
ILMN
28.8%
24.3%
PTC
More free cash flow
PTC
PTC
$404.0K more FCF
PTC
$267.4M
$267.0M
ILMN
Faster 2-yr revenue CAGR
PTC
PTC
Annualised
PTC
6.6%
-0.7%
ILMN

Income Statement — Q4 FY2025 vs Q1 FY2026

Metric
ILMN
ILMN
PTC
PTC
Revenue
$1.2B
$685.8M
Net Profit
$334.0M
$166.5M
Gross Margin
65.5%
82.8%
Operating Margin
17.4%
32.2%
Net Margin
28.8%
24.3%
Revenue YoY
5.0%
21.4%
Net Profit YoY
185.5%
102.5%
EPS (diluted)
$2.16
$1.39

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ILMN
ILMN
PTC
PTC
Q4 25
$1.2B
$685.8M
Q3 25
$893.8M
Q2 25
$643.9M
Q1 25
$636.4M
Q4 24
$1.1B
$565.1M
Q3 24
$1.1B
$626.5M
Q2 24
$1.1B
$518.6M
Q1 24
$1.1B
$603.1M
Net Profit
ILMN
ILMN
PTC
PTC
Q4 25
$334.0M
$166.5M
Q3 25
$347.8M
Q2 25
$141.3M
Q1 25
$162.6M
Q4 24
$186.0M
$82.2M
Q3 24
$705.0M
$126.5M
Q2 24
$-2.0B
$69.0M
Q1 24
$-126.0M
$114.4M
Gross Margin
ILMN
ILMN
PTC
PTC
Q4 25
65.5%
82.8%
Q3 25
86.9%
Q2 25
82.9%
Q1 25
83.3%
Q4 24
65.9%
80.2%
Q3 24
69.0%
82.0%
Q2 24
64.8%
78.4%
Q1 24
62.0%
81.8%
Operating Margin
ILMN
ILMN
PTC
PTC
Q4 25
17.4%
32.2%
Q3 25
48.5%
Q2 25
32.6%
Q1 25
35.1%
Q4 24
15.8%
20.4%
Q3 24
68.6%
31.0%
Q2 24
-147.2%
18.5%
Q1 24
-10.3%
29.8%
Net Margin
ILMN
ILMN
PTC
PTC
Q4 25
28.8%
24.3%
Q3 25
38.9%
Q2 25
21.9%
Q1 25
25.6%
Q4 24
16.8%
14.6%
Q3 24
65.3%
20.2%
Q2 24
-178.8%
13.3%
Q1 24
-11.7%
19.0%
EPS (diluted)
ILMN
ILMN
PTC
PTC
Q4 25
$2.16
$1.39
Q3 25
$2.88
Q2 25
$1.17
Q1 25
$1.35
Q4 24
$1.16
$0.68
Q3 24
$4.42
$1.05
Q2 24
$-12.48
$0.57
Q1 24
$-0.79
$0.95

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ILMN
ILMN
PTC
PTC
Cash + ST InvestmentsLiquidity on hand
$1.6B
$209.7M
Total DebtLower is stronger
$1.2B
Stockholders' EquityBook value
$2.7B
$3.8B
Total Assets
$6.6B
$6.4B
Debt / EquityLower = less leverage
0.31×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ILMN
ILMN
PTC
PTC
Q4 25
$1.6B
$209.7M
Q3 25
$184.4M
Q2 25
$199.3M
Q1 25
$235.2M
Q4 24
$93.0M
$196.3M
Q3 24
$70.0M
$265.8M
Q2 24
$74.0M
$247.7M
Q1 24
$249.0M
Total Debt
ILMN
ILMN
PTC
PTC
Q4 25
$1.2B
Q3 25
$1.2B
Q2 25
$1.2B
Q1 25
$1.4B
Q4 24
$1.0B
Q3 24
$1.2B
Q2 24
$1.3B
Q1 24
$1.5B
Stockholders' Equity
ILMN
ILMN
PTC
PTC
Q4 25
$2.7B
$3.8B
Q3 25
$3.8B
Q2 25
$3.5B
Q1 25
$3.4B
Q4 24
$2.4B
$3.2B
Q3 24
$2.1B
$3.2B
Q2 24
$1.4B
$3.0B
Q1 24
$5.7B
$2.9B
Total Assets
ILMN
ILMN
PTC
PTC
Q4 25
$6.6B
$6.4B
Q3 25
$6.6B
Q2 25
$6.2B
Q1 25
$6.2B
Q4 24
$6.3B
$6.1B
Q3 24
$6.0B
$6.4B
Q2 24
$6.1B
$6.1B
Q1 24
$10.0B
$6.2B
Debt / Equity
ILMN
ILMN
PTC
PTC
Q4 25
0.31×
Q3 25
0.31×
Q2 25
0.34×
Q1 25
0.40×
Q4 24
0.32×
Q3 24
0.38×
Q2 24
0.43×
Q1 24
0.51×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ILMN
ILMN
PTC
PTC
Operating Cash FlowLast quarter
$321.0M
$269.7M
Free Cash FlowOCF − Capex
$267.0M
$267.4M
FCF MarginFCF / Revenue
23.0%
39.0%
Capex IntensityCapex / Revenue
0.3%
Cash ConversionOCF / Net Profit
0.96×
1.62×
TTM Free Cash FlowTrailing 4 quarters
$935.0M
$888.4M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ILMN
ILMN
PTC
PTC
Q4 25
$321.0M
$269.7M
Q3 25
$104.0M
Q2 25
$243.9M
Q1 25
$281.3M
Q4 24
$364.0M
$238.4M
Q3 24
$316.0M
$98.1M
Q2 24
$80.0M
$213.8M
Q1 24
$77.0M
$250.7M
Free Cash Flow
ILMN
ILMN
PTC
PTC
Q4 25
$267.0M
$267.4M
Q3 25
$100.5M
Q2 25
$242.0M
Q1 25
$278.5M
Q4 24
$335.0M
$235.7M
Q3 24
$284.0M
$93.6M
Q2 24
$49.0M
$212.2M
Q1 24
$41.0M
$247.1M
FCF Margin
ILMN
ILMN
PTC
PTC
Q4 25
23.0%
39.0%
Q3 25
11.2%
Q2 25
37.6%
Q1 25
43.8%
Q4 24
30.3%
41.7%
Q3 24
26.3%
14.9%
Q2 24
4.4%
40.9%
Q1 24
3.8%
41.0%
Capex Intensity
ILMN
ILMN
PTC
PTC
Q4 25
0.3%
Q3 25
0.4%
Q2 25
0.3%
Q1 25
0.4%
Q4 24
2.6%
0.5%
Q3 24
3.0%
0.7%
Q2 24
2.8%
0.3%
Q1 24
3.3%
0.6%
Cash Conversion
ILMN
ILMN
PTC
PTC
Q4 25
0.96×
1.62×
Q3 25
0.30×
Q2 25
1.73×
Q1 25
1.73×
Q4 24
1.96×
2.90×
Q3 24
0.45×
0.78×
Q2 24
3.10×
Q1 24
2.19×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ILMN
ILMN

Product revenue$990.0M85%
Service and other revenue$169.0M15%

PTC
PTC

Support And Cloud Services$393.3M57%
License$269.7M39%
Technology Service$22.9M3%
Perpetual License$5.6M1%

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