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Side-by-side financial comparison of INSMED Inc (INSM) and MEDICAL PROPERTIES TRUST INC (MPW). Click either name above to swap in a different company.

MEDICAL PROPERTIES TRUST INC is the larger business by last-quarter revenue ($270.3M vs $263.8M, roughly 1.0× INSMED Inc). MEDICAL PROPERTIES TRUST INC runs the higher net margin — 6.5% vs -124.5%, a 131.0% gap on every dollar of revenue. On growth, INSMED Inc posted the faster year-over-year revenue change (152.6% vs 16.6%). Over the past eight quarters, INSMED Inc's revenue compounded faster (86.9% CAGR vs -0.2%).

Insmed Inc. is a global biopharmaceutical firm focused on developing and commercializing innovative therapies for patients with serious rare diseases that have high unmet medical needs. Its key offerings target pulmonary and endocrine rare disorders, serving markets across North America, Europe, and Asia Pacific.

Medical Properties Trust, Inc. (MPT) is an international real estate investment trust (REIT) based in Birmingham, Alabama that purchases and invests in healthcare facilities and for-profit healthcare holding companies, primarily in the United States and Europe. Their property acquisitions often come in the form of sale-leaseback agreements, in which the original property owner sells the property to MPT and becomes their tenant. MPT's tenants are generally subject to long-term triple net lease...

INSM vs MPW — Head-to-Head

Bigger by revenue
MPW
MPW
1.0× larger
MPW
$270.3M
$263.8M
INSM
Growing faster (revenue YoY)
INSM
INSM
+136.0% gap
INSM
152.6%
16.6%
MPW
Higher net margin
MPW
MPW
131.0% more per $
MPW
6.5%
-124.5%
INSM
Faster 2-yr revenue CAGR
INSM
INSM
Annualised
INSM
86.9%
-0.2%
MPW

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
INSM
INSM
MPW
MPW
Revenue
$263.8M
$270.3M
Net Profit
$-328.5M
$17.6M
Gross Margin
83.2%
95.8%
Operating Margin
-121.2%
9.7%
Net Margin
-124.5%
6.5%
Revenue YoY
152.6%
16.6%
Net Profit YoY
-39.5%
104.3%
EPS (diluted)
$-1.55
$0.03

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
INSM
INSM
MPW
MPW
Q4 25
$263.8M
$270.3M
Q3 25
$142.3M
$237.5M
Q2 25
$107.4M
$240.4M
Q1 25
$92.8M
$223.8M
Q4 24
$104.4M
$231.8M
Q3 24
$93.4M
$225.8M
Q2 24
$90.3M
$266.6M
Q1 24
$75.5M
$271.3M
Net Profit
INSM
INSM
MPW
MPW
Q4 25
$-328.5M
$17.6M
Q3 25
$-370.0M
$-77.7M
Q2 25
$-321.7M
$-98.4M
Q1 25
$-256.6M
$-118.3M
Q4 24
$-235.5M
$-412.3M
Q3 24
$-220.5M
$-801.2M
Q2 24
$-300.6M
$-320.6M
Q1 24
$-157.1M
$-875.6M
Gross Margin
INSM
INSM
MPW
MPW
Q4 25
83.2%
95.8%
Q3 25
79.4%
Q2 25
73.9%
91.8%
Q1 25
77.1%
63.6%
Q4 24
75.0%
90.9%
Q3 24
77.3%
96.5%
Q2 24
76.8%
98.4%
Q1 24
76.9%
84.9%
Operating Margin
INSM
INSM
MPW
MPW
Q4 25
-121.2%
9.7%
Q3 25
-257.1%
-28.0%
Q2 25
-291.3%
-36.7%
Q1 25
-267.3%
-48.5%
Q4 24
-220.6%
-173.7%
Q3 24
-228.4%
-350.7%
Q2 24
-319.8%
-114.5%
Q1 24
-192.7%
-318.6%
Net Margin
INSM
INSM
MPW
MPW
Q4 25
-124.5%
6.5%
Q3 25
-260.0%
-32.7%
Q2 25
-299.5%
-40.9%
Q1 25
-276.4%
-52.8%
Q4 24
-225.5%
-177.8%
Q3 24
-236.0%
-354.8%
Q2 24
-332.8%
-120.3%
Q1 24
-208.1%
-322.7%
EPS (diluted)
INSM
INSM
MPW
MPW
Q4 25
$-1.55
$0.03
Q3 25
$-1.75
$-0.13
Q2 25
$-1.70
$-0.16
Q1 25
$-1.42
$-0.20
Q4 24
$-1.30
$-0.68
Q3 24
$-1.27
$-1.34
Q2 24
$-1.94
$-0.54
Q1 24
$-1.06
$-1.46

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
INSM
INSM
MPW
MPW
Cash + ST InvestmentsLiquidity on hand
$1.4B
$540.9M
Total DebtLower is stronger
$546.8M
$9.7B
Stockholders' EquityBook value
$739.0M
$4.6B
Total Assets
$2.3B
$15.0B
Debt / EquityLower = less leverage
0.74×
2.11×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
INSM
INSM
MPW
MPW
Q4 25
$1.4B
$540.9M
Q3 25
$1.7B
$396.6M
Q2 25
$1.9B
$509.8M
Q1 25
$1.2B
$673.5M
Q4 24
$1.4B
$332.3M
Q3 24
$1.5B
$275.6M
Q2 24
$1.2B
$606.5M
Q1 24
$595.7M
$224.3M
Total Debt
INSM
INSM
MPW
MPW
Q4 25
$546.8M
$9.7B
Q3 25
$546.8M
$9.6B
Q2 25
$546.8M
$9.6B
Q1 25
$1.1B
$9.5B
Q4 24
$1.1B
$8.8B
Q3 24
$971.8M
$9.2B
Q2 24
$1.2B
$9.4B
Q1 24
$1.2B
$10.1B
Stockholders' Equity
INSM
INSM
MPW
MPW
Q4 25
$739.0M
$4.6B
Q3 25
$945.6M
$4.7B
Q2 25
$1.2B
$4.8B
Q1 25
$99.2M
$4.8B
Q4 24
$285.4M
$4.8B
Q3 24
$483.4M
$5.4B
Q2 24
$38.8M
$6.2B
Q1 24
$-464.8M
$6.7B
Total Assets
INSM
INSM
MPW
MPW
Q4 25
$2.3B
$15.0B
Q3 25
$2.4B
$14.9B
Q2 25
$2.5B
$15.2B
Q1 25
$1.8B
$14.9B
Q4 24
$2.0B
$14.3B
Q3 24
$2.1B
$15.2B
Q2 24
$1.8B
$16.2B
Q1 24
$1.2B
$17.3B
Debt / Equity
INSM
INSM
MPW
MPW
Q4 25
0.74×
2.11×
Q3 25
0.58×
2.06×
Q2 25
0.44×
2.00×
Q1 25
11.31×
1.99×
Q4 24
3.93×
1.83×
Q3 24
2.01×
1.69×
Q2 24
30.66×
1.51×
Q1 24
1.51×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
INSM
INSM
MPW
MPW
Operating Cash FlowLast quarter
$-247.6M
$230.8M
Free Cash FlowOCF − Capex
$-264.2M
FCF MarginFCF / Revenue
-100.1%
Capex IntensityCapex / Revenue
6.3%
Cash ConversionOCF / Net Profit
13.11×
TTM Free Cash FlowTrailing 4 quarters
$-967.6M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
INSM
INSM
MPW
MPW
Q4 25
$-247.6M
$230.8M
Q3 25
$-219.8M
$18.6M
Q2 25
$-205.6M
$51.7M
Q1 25
$-262.1M
$384.0K
Q4 24
$-196.0M
$245.5M
Q3 24
$-180.9M
$59.2M
Q2 24
$-123.0M
$35.3M
Q1 24
$-184.0M
$74.3M
Free Cash Flow
INSM
INSM
MPW
MPW
Q4 25
$-264.2M
Q3 25
$-222.2M
Q2 25
$-209.1M
Q1 25
$-272.2M
Q4 24
$-202.8M
Q3 24
$-184.6M
Q2 24
$-129.7M
Q1 24
$-188.7M
FCF Margin
INSM
INSM
MPW
MPW
Q4 25
-100.1%
Q3 25
-156.1%
Q2 25
-194.6%
Q1 25
-293.2%
Q4 24
-194.1%
Q3 24
-197.6%
Q2 24
-143.6%
Q1 24
-250.0%
Capex Intensity
INSM
INSM
MPW
MPW
Q4 25
6.3%
Q3 25
1.7%
Q2 25
3.2%
Q1 25
10.8%
Q4 24
6.5%
Q3 24
3.9%
Q2 24
7.5%
Q1 24
6.2%
Cash Conversion
INSM
INSM
MPW
MPW
Q4 25
13.11×
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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