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Side-by-side financial comparison of IOVANCE BIOTHERAPEUTICS, INC. (IOVA) and iQSTEL Inc (IQST). Click either name above to swap in a different company.

IOVANCE BIOTHERAPEUTICS, INC. is the larger business by last-quarter revenue ($86.8M vs $84.2M, roughly 1.0× iQSTEL Inc). On growth, IOVANCE BIOTHERAPEUTICS, INC. posted the faster year-over-year revenue change (17.7% vs -14.9%). iQSTEL Inc produced more free cash flow last quarter ($-1.2M vs $-61.9M). Over the past eight quarters, IOVANCE BIOTHERAPEUTICS, INC.'s revenue compounded faster (1001.6% CAGR vs 28.0%).

Iovance Biotherapeutics, Inc. is a biopharmaceutical startup based in San Carlos, California. The company works to develop tumor-infiltrating lymphocyte (TIL) therapies against cancer.

iQSTEL Inc is a technology holding company operating three core segments: telecommunications, Internet of Things (IoT), and fintech. It offers connectivity services, smart IoT monitoring solutions, and digital financial tools, mainly serving small and medium-sized enterprises and retail customers in North and South American markets.

IOVA vs IQST — Head-to-Head

Bigger by revenue
IOVA
IOVA
1.0× larger
IOVA
$86.8M
$84.2M
IQST
Growing faster (revenue YoY)
IOVA
IOVA
+32.6% gap
IOVA
17.7%
-14.9%
IQST
More free cash flow
IQST
IQST
$60.6M more FCF
IQST
$-1.2M
$-61.9M
IOVA
Faster 2-yr revenue CAGR
IOVA
IOVA
Annualised
IOVA
1001.6%
28.0%
IQST

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
IOVA
IOVA
IQST
IQST
Revenue
$86.8M
$84.2M
Net Profit
$-2.7M
Gross Margin
67.4%
3.5%
Operating Margin
-84.7%
-2.9%
Net Margin
-3.2%
Revenue YoY
17.7%
-14.9%
Net Profit YoY
-44.5%
EPS (diluted)
$-0.92

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
IOVA
IOVA
IQST
IQST
Q4 25
$86.8M
$84.2M
Q3 25
$67.5M
$102.9M
Q2 25
$60.0M
$72.2M
Q1 25
$49.3M
$57.6M
Q4 24
$73.7M
$98.9M
Q3 24
$58.6M
$54.2M
Q2 24
$31.1M
$78.6M
Q1 24
$715.0K
$51.4M
Net Profit
IOVA
IOVA
IQST
IQST
Q4 25
$-2.7M
Q3 25
$-91.3M
$-2.3M
Q2 25
$-111.7M
$-2.3M
Q1 25
$-116.2M
$-1.1M
Q4 24
$-1.9M
Q3 24
$-83.5M
$-773.0K
Q2 24
$-97.1M
$-2.0M
Q1 24
$-113.0M
$-580.2K
Gross Margin
IOVA
IOVA
IQST
IQST
Q4 25
67.4%
3.5%
Q3 25
43.0%
2.7%
Q2 25
5.5%
2.6%
Q1 25
-0.8%
3.4%
Q4 24
68.7%
2.7%
Q3 24
46.2%
3.7%
Q2 24
-0.8%
2.8%
Q1 24
2.7%
Operating Margin
IOVA
IOVA
IQST
IQST
Q4 25
-84.7%
-2.9%
Q3 25
-140.7%
-0.5%
Q2 25
-189.8%
-0.9%
Q1 25
-245.8%
-1.0%
Q4 24
-117.5%
-0.3%
Q3 24
-152.1%
-0.1%
Q2 24
-327.6%
-0.4%
Q1 24
-16464.6%
-0.4%
Net Margin
IOVA
IOVA
IQST
IQST
Q4 25
-3.2%
Q3 25
-135.3%
-2.3%
Q2 25
-186.2%
-3.3%
Q1 25
-235.5%
-2.0%
Q4 24
-1.9%
Q3 24
-142.7%
-1.4%
Q2 24
-312.2%
-2.5%
Q1 24
-15800.8%
-1.1%
EPS (diluted)
IOVA
IOVA
IQST
IQST
Q4 25
$-0.92
Q3 25
$-0.68
Q2 25
$-0.33
$-0.82
Q1 25
$-0.36
$-0.44
Q4 24
$-0.24
$-1.19
Q3 24
$-0.28
$-0.40
Q2 24
$-0.34
$-0.90
Q1 24
$-0.42
$-0.37

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
IOVA
IOVA
IQST
IQST
Cash + ST InvestmentsLiquidity on hand
$297.0M
$2.2M
Total DebtLower is stronger
$4.1M
Stockholders' EquityBook value
$698.6M
$16.3M
Total Assets
$913.2M
$51.1M
Debt / EquityLower = less leverage
0.25×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
IOVA
IOVA
IQST
IQST
Q4 25
$297.0M
$2.2M
Q3 25
$300.8M
$2.3M
Q2 25
$301.2M
$2.0M
Q1 25
$359.7M
$1.1M
Q4 24
$323.8M
$2.5M
Q3 24
$397.5M
$2.1M
Q2 24
$412.5M
$797.2K
Q1 24
$356.2M
$2.7M
Total Debt
IOVA
IOVA
IQST
IQST
Q4 25
$4.1M
Q3 25
$2.7M
Q2 25
$4.5M
Q1 25
$3.5M
Q4 24
$2.5M
Q3 24
$3.2M
Q2 24
$2.5M
Q1 24
$194.0K
Stockholders' Equity
IOVA
IOVA
IQST
IQST
Q4 25
$698.6M
$16.3M
Q3 25
$702.3M
$17.9M
Q2 25
$698.5M
$14.3M
Q1 25
$767.9M
$11.6M
Q4 24
$710.4M
$11.9M
Q3 24
$773.5M
$8.1M
Q2 24
$768.5M
$7.6M
Q1 24
$680.0M
$8.4M
Total Assets
IOVA
IOVA
IQST
IQST
Q4 25
$913.2M
$51.1M
Q3 25
$904.9M
$46.9M
Q2 25
$907.4M
$51.4M
Q1 25
$966.7M
$42.0M
Q4 24
$910.4M
$79.0M
Q3 24
$991.1M
$32.4M
Q2 24
$964.3M
$30.0M
Q1 24
$869.8M
$22.1M
Debt / Equity
IOVA
IOVA
IQST
IQST
Q4 25
0.25×
Q3 25
0.15×
Q2 25
0.31×
Q1 25
0.31×
Q4 24
0.21×
Q3 24
0.40×
Q2 24
0.34×
Q1 24
0.02×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
IOVA
IOVA
IQST
IQST
Operating Cash FlowLast quarter
$-52.6M
$-1.2M
Free Cash FlowOCF − Capex
$-61.9M
$-1.2M
FCF MarginFCF / Revenue
-71.3%
-1.5%
Capex IntensityCapex / Revenue
10.7%
0.0%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-336.2M
$-4.0M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
IOVA
IOVA
IQST
IQST
Q4 25
$-52.6M
$-1.2M
Q3 25
$-78.7M
$-953.0K
Q2 25
$-67.4M
$257.7K
Q1 25
$-103.7M
$-1.9M
Q4 24
$-73.3M
$-403.7K
Q3 24
$-59.0M
$625.0K
Q2 24
$-98.4M
$-2.6M
Q1 24
$-122.3M
$-536.9K
Free Cash Flow
IOVA
IOVA
IQST
IQST
Q4 25
$-61.9M
$-1.2M
Q3 25
$-89.5M
$-969.2K
Q2 25
$-74.9M
$211.7K
Q1 25
$-109.9M
$-2.0M
Q4 24
$-77.5M
$-421.3K
Q3 24
$-61.3M
$594.5K
Q2 24
$-98.9M
$-2.6M
Q1 24
$-126.5M
$-608.5K
FCF Margin
IOVA
IOVA
IQST
IQST
Q4 25
-71.3%
-1.5%
Q3 25
-132.7%
-0.9%
Q2 25
-124.9%
0.3%
Q1 25
-222.8%
-3.4%
Q4 24
-105.1%
-0.4%
Q3 24
-104.6%
1.1%
Q2 24
-317.9%
-3.4%
Q1 24
-17685.3%
-1.2%
Capex Intensity
IOVA
IOVA
IQST
IQST
Q4 25
10.7%
0.0%
Q3 25
16.1%
0.0%
Q2 25
12.4%
0.1%
Q1 25
12.6%
0.1%
Q4 24
5.7%
0.0%
Q3 24
3.9%
0.1%
Q2 24
1.4%
0.0%
Q1 24
583.4%
0.1%

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

IOVA
IOVA

Amtagvi$64.9M75%
Proleukin$21.9M25%

IQST
IQST

USA$53.2M63%
Other$29.9M35%
Switzerland$1.1M1%

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