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Side-by-side financial comparison of IOVANCE BIOTHERAPEUTICS, INC. (IOVA) and Mayville Engineering Company, Inc. (MEC). Click either name above to swap in a different company.

Mayville Engineering Company, Inc. is the larger business by last-quarter revenue ($134.3M vs $86.8M, roughly 1.5× IOVANCE BIOTHERAPEUTICS, INC.). On growth, IOVANCE BIOTHERAPEUTICS, INC. posted the faster year-over-year revenue change (17.7% vs 10.7%). Mayville Engineering Company, Inc. produced more free cash flow last quarter ($10.2M vs $-61.9M). Over the past eight quarters, IOVANCE BIOTHERAPEUTICS, INC.'s revenue compounded faster (1001.6% CAGR vs -8.8%).

Iovance Biotherapeutics, Inc. is a biopharmaceutical startup based in San Carlos, California. The company works to develop tumor-infiltrating lymphocyte (TIL) therapies against cancer.

Mayville Engineering Company, Inc. is a U.S.-headquartered leading manufacturer of metal components, fabricated assemblies, and custom engineered solutions. It serves OEM clients across agriculture, construction, transportation, defense, and power sports markets, offering end-to-end services from prototyping to high-volume production for North America.

IOVA vs MEC — Head-to-Head

Bigger by revenue
MEC
MEC
1.5× larger
MEC
$134.3M
$86.8M
IOVA
Growing faster (revenue YoY)
IOVA
IOVA
+7.1% gap
IOVA
17.7%
10.7%
MEC
More free cash flow
MEC
MEC
$72.0M more FCF
MEC
$10.2M
$-61.9M
IOVA
Faster 2-yr revenue CAGR
IOVA
IOVA
Annualised
IOVA
1001.6%
-8.8%
MEC

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
IOVA
IOVA
MEC
MEC
Revenue
$86.8M
$134.3M
Net Profit
$-4.4M
Gross Margin
67.4%
6.8%
Operating Margin
-84.7%
-4.1%
Net Margin
-3.2%
Revenue YoY
17.7%
10.7%
Net Profit YoY
-127.3%
EPS (diluted)
$-0.22

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
IOVA
IOVA
MEC
MEC
Q4 25
$86.8M
$134.3M
Q3 25
$67.5M
$144.3M
Q2 25
$60.0M
$132.3M
Q1 25
$49.3M
$135.6M
Q4 24
$73.7M
$121.3M
Q3 24
$58.6M
$135.4M
Q2 24
$31.1M
$163.6M
Q1 24
$715.0K
$161.3M
Net Profit
IOVA
IOVA
MEC
MEC
Q4 25
$-4.4M
Q3 25
$-91.3M
$-2.7M
Q2 25
$-111.7M
$-1.1M
Q1 25
$-116.2M
$20.0K
Q4 24
$16.0M
Q3 24
$-83.5M
$3.0M
Q2 24
$-97.1M
$3.8M
Q1 24
$-113.0M
$3.2M
Gross Margin
IOVA
IOVA
MEC
MEC
Q4 25
67.4%
6.8%
Q3 25
43.0%
11.0%
Q2 25
5.5%
10.3%
Q1 25
-0.8%
11.3%
Q4 24
68.7%
8.9%
Q3 24
46.2%
12.6%
Q2 24
-0.8%
13.6%
Q1 24
13.0%
Operating Margin
IOVA
IOVA
MEC
MEC
Q4 25
-84.7%
-4.1%
Q3 25
-140.7%
0.0%
Q2 25
-189.8%
0.1%
Q1 25
-245.8%
1.2%
Q4 24
-117.5%
19.0%
Q3 24
-152.1%
4.2%
Q2 24
-327.6%
5.0%
Q1 24
-16464.6%
4.7%
Net Margin
IOVA
IOVA
MEC
MEC
Q4 25
-3.2%
Q3 25
-135.3%
-1.9%
Q2 25
-186.2%
-0.8%
Q1 25
-235.5%
0.0%
Q4 24
13.2%
Q3 24
-142.7%
2.2%
Q2 24
-312.2%
2.3%
Q1 24
-15800.8%
2.0%
EPS (diluted)
IOVA
IOVA
MEC
MEC
Q4 25
$-0.22
Q3 25
$-0.13
Q2 25
$-0.33
$-0.05
Q1 25
$-0.36
$0.00
Q4 24
$-0.24
$0.76
Q3 24
$-0.28
$0.14
Q2 24
$-0.34
$0.18
Q1 24
$-0.42
$0.16

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
IOVA
IOVA
MEC
MEC
Cash + ST InvestmentsLiquidity on hand
$297.0M
$1.5M
Total DebtLower is stronger
Stockholders' EquityBook value
$698.6M
$240.7M
Total Assets
$913.2M
$563.6M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
IOVA
IOVA
MEC
MEC
Q4 25
$297.0M
$1.5M
Q3 25
$300.8M
$1.2M
Q2 25
$301.2M
$206.0K
Q1 25
$359.7M
$183.0K
Q4 24
$323.8M
$206.0K
Q3 24
$397.5M
$178.0K
Q2 24
$412.5M
$314.0K
Q1 24
$356.2M
$314.0K
Stockholders' Equity
IOVA
IOVA
MEC
MEC
Q4 25
$698.6M
$240.7M
Q3 25
$702.3M
$244.8M
Q2 25
$698.5M
$246.8M
Q1 25
$767.9M
$250.0M
Q4 24
$710.4M
$251.8M
Q3 24
$773.5M
$238.4M
Q2 24
$768.5M
$238.1M
Q1 24
$680.0M
$234.0M
Total Assets
IOVA
IOVA
MEC
MEC
Q4 25
$913.2M
$563.6M
Q3 25
$904.9M
$585.6M
Q2 25
$907.4M
$433.7M
Q1 25
$966.7M
$447.7M
Q4 24
$910.4M
$445.6M
Q3 24
$991.1M
$466.0M
Q2 24
$964.3M
$488.2M
Q1 24
$869.8M
$499.9M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
IOVA
IOVA
MEC
MEC
Operating Cash FlowLast quarter
$-52.6M
$13.4M
Free Cash FlowOCF − Capex
$-61.9M
$10.2M
FCF MarginFCF / Revenue
-71.3%
7.6%
Capex IntensityCapex / Revenue
10.7%
2.4%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-336.2M
$26.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
IOVA
IOVA
MEC
MEC
Q4 25
$-52.6M
$13.4M
Q3 25
$-78.7M
$1.9M
Q2 25
$-67.4M
$15.0M
Q1 25
$-103.7M
$8.3M
Q4 24
$-73.3M
$38.0M
Q3 24
$-59.0M
$17.9M
Q2 24
$-98.4M
$23.3M
Q1 24
$-122.3M
$10.6M
Free Cash Flow
IOVA
IOVA
MEC
MEC
Q4 25
$-61.9M
$10.2M
Q3 25
$-89.5M
$-1.1M
Q2 25
$-74.9M
$12.5M
Q1 25
$-109.9M
$5.4M
Q4 24
$-77.5M
$35.6M
Q3 24
$-61.3M
$15.1M
Q2 24
$-98.9M
$19.2M
Q1 24
$-126.5M
$7.8M
FCF Margin
IOVA
IOVA
MEC
MEC
Q4 25
-71.3%
7.6%
Q3 25
-132.7%
-0.8%
Q2 25
-124.9%
9.5%
Q1 25
-222.8%
4.0%
Q4 24
-105.1%
29.4%
Q3 24
-104.6%
11.1%
Q2 24
-317.9%
11.7%
Q1 24
-17685.3%
4.9%
Capex Intensity
IOVA
IOVA
MEC
MEC
Q4 25
10.7%
2.4%
Q3 25
16.1%
2.1%
Q2 25
12.4%
1.8%
Q1 25
12.6%
2.2%
Q4 24
5.7%
1.9%
Q3 24
3.9%
2.1%
Q2 24
1.4%
2.5%
Q1 24
583.4%
1.7%
Cash Conversion
IOVA
IOVA
MEC
MEC
Q4 25
Q3 25
Q2 25
Q1 25
416.65×
Q4 24
2.38×
Q3 24
6.03×
Q2 24
6.15×
Q1 24
3.28×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

IOVA
IOVA

Amtagvi$64.9M75%
Proleukin$21.9M25%

MEC
MEC

Fabrication$72.2M54%
Construction And Access$19.2M14%
Tubes$16.2M12%
Other Market$11.9M9%
Agriculture$7.7M6%
Military$6.7M5%
Outdoor Sports$1.7M1%

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