vs
Side-by-side financial comparison of IOVANCE BIOTHERAPEUTICS, INC. (IOVA) and MFA FINANCIAL, INC. (MFA). Click either name above to swap in a different company.
IOVANCE BIOTHERAPEUTICS, INC. is the larger business by last-quarter revenue ($86.8M vs $55.5M, roughly 1.6× MFA FINANCIAL, INC.). On growth, IOVANCE BIOTHERAPEUTICS, INC. posted the faster year-over-year revenue change (17.7% vs 9.2%). Over the past eight quarters, IOVANCE BIOTHERAPEUTICS, INC.'s revenue compounded faster (1001.6% CAGR vs 7.7%).
Iovance Biotherapeutics, Inc. is a biopharmaceutical startup based in San Carlos, California. The company works to develop tumor-infiltrating lymphocyte (TIL) therapies against cancer.
MFA Financial, Inc. is a U.S.-headquartered real estate investment trust (REIT) specializing in investing in and managing residential and commercial mortgage-backed securities, mortgage loans, and other real estate-related financial assets. It caters primarily to institutional and individual investors across the U.S., focusing on delivering stable risk-adjusted returns via rigorous asset screening and risk management frameworks.
IOVA vs MFA — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $86.8M | $55.5M |
| Net Profit | — | — |
| Gross Margin | 67.4% | — |
| Operating Margin | -84.7% | 97.9% |
| Net Margin | — | — |
| Revenue YoY | 17.7% | 9.2% |
| Net Profit YoY | — | — |
| EPS (diluted) | — | $0.43 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $86.8M | $55.5M | ||
| Q3 25 | $67.5M | $56.8M | ||
| Q2 25 | $60.0M | $61.3M | ||
| Q1 25 | $49.3M | $57.5M | ||
| Q4 24 | $73.7M | $50.8M | ||
| Q3 24 | $58.6M | $50.6M | ||
| Q2 24 | $31.1M | $53.5M | ||
| Q1 24 | $715.0K | $47.8M |
| Q4 25 | — | — | ||
| Q3 25 | $-91.3M | $48.1M | ||
| Q2 25 | $-111.7M | $33.2M | ||
| Q1 25 | $-116.2M | $41.2M | ||
| Q4 24 | — | — | ||
| Q3 24 | $-83.5M | $48.2M | ||
| Q2 24 | $-97.1M | $41.9M | ||
| Q1 24 | $-113.0M | $23.2M |
| Q4 25 | 67.4% | — | ||
| Q3 25 | 43.0% | — | ||
| Q2 25 | 5.5% | — | ||
| Q1 25 | -0.8% | — | ||
| Q4 24 | 68.7% | — | ||
| Q3 24 | 46.2% | — | ||
| Q2 24 | -0.8% | — | ||
| Q1 24 | — | — |
| Q4 25 | -84.7% | 97.9% | ||
| Q3 25 | -140.7% | 84.5% | ||
| Q2 25 | -189.8% | 54.5% | ||
| Q1 25 | -245.8% | 70.0% | ||
| Q4 24 | -117.5% | 6.8% | ||
| Q3 24 | -152.1% | 98.2% | ||
| Q2 24 | -327.6% | 79.1% | ||
| Q1 24 | -16464.6% | 50.7% |
| Q4 25 | — | — | ||
| Q3 25 | -135.3% | 84.7% | ||
| Q2 25 | -186.2% | 54.2% | ||
| Q1 25 | -235.5% | 71.6% | ||
| Q4 24 | — | — | ||
| Q3 24 | -142.7% | 95.2% | ||
| Q2 24 | -312.2% | 78.4% | ||
| Q1 24 | -15800.8% | 48.5% |
| Q4 25 | — | $0.43 | ||
| Q3 25 | — | $0.35 | ||
| Q2 25 | $-0.33 | $0.21 | ||
| Q1 25 | $-0.36 | $0.31 | ||
| Q4 24 | $-0.24 | $-0.01 | ||
| Q3 24 | $-0.28 | $0.37 | ||
| Q2 24 | $-0.34 | $0.32 | ||
| Q1 24 | $-0.42 | $0.14 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $297.0M | $213.2M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $698.6M | $1.8B |
| Total Assets | $913.2M | $13.0B |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $297.0M | $213.2M | ||
| Q3 25 | $300.8M | $305.2M | ||
| Q2 25 | $301.2M | $275.7M | ||
| Q1 25 | $359.7M | $253.7M | ||
| Q4 24 | $323.8M | $338.9M | ||
| Q3 24 | $397.5M | $305.6M | ||
| Q2 24 | $412.5M | $289.4M | ||
| Q1 24 | $356.2M | $306.3M |
| Q4 25 | $698.6M | $1.8B | ||
| Q3 25 | $702.3M | $1.8B | ||
| Q2 25 | $698.5M | $1.8B | ||
| Q1 25 | $767.9M | $1.8B | ||
| Q4 24 | $710.4M | $1.8B | ||
| Q3 24 | $773.5M | $1.9B | ||
| Q2 24 | $768.5M | $1.9B | ||
| Q1 24 | $680.0M | $1.9B |
| Q4 25 | $913.2M | $13.0B | ||
| Q3 25 | $904.9M | $12.1B | ||
| Q2 25 | $907.4M | $11.7B | ||
| Q1 25 | $966.7M | $11.5B | ||
| Q4 24 | $910.4M | $11.4B | ||
| Q3 24 | $991.1M | $11.2B | ||
| Q2 24 | $964.3M | $11.1B | ||
| Q1 24 | $869.8M | $10.9B |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-52.6M | $76.2M |
| Free Cash FlowOCF − Capex | $-61.9M | — |
| FCF MarginFCF / Revenue | -71.3% | — |
| Capex IntensityCapex / Revenue | 10.7% | — |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $-336.2M | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-52.6M | $76.2M | ||
| Q3 25 | $-78.7M | $14.7M | ||
| Q2 25 | $-67.4M | $38.5M | ||
| Q1 25 | $-103.7M | $-14.6M | ||
| Q4 24 | $-73.3M | $200.1M | ||
| Q3 24 | $-59.0M | $-11.3M | ||
| Q2 24 | $-98.4M | $46.5M | ||
| Q1 24 | $-122.3M | $53.5M |
| Q4 25 | $-61.9M | — | ||
| Q3 25 | $-89.5M | — | ||
| Q2 25 | $-74.9M | — | ||
| Q1 25 | $-109.9M | — | ||
| Q4 24 | $-77.5M | — | ||
| Q3 24 | $-61.3M | — | ||
| Q2 24 | $-98.9M | — | ||
| Q1 24 | $-126.5M | — |
| Q4 25 | -71.3% | — | ||
| Q3 25 | -132.7% | — | ||
| Q2 25 | -124.9% | — | ||
| Q1 25 | -222.8% | — | ||
| Q4 24 | -105.1% | — | ||
| Q3 24 | -104.6% | — | ||
| Q2 24 | -317.9% | — | ||
| Q1 24 | -17685.3% | — |
| Q4 25 | 10.7% | — | ||
| Q3 25 | 16.1% | — | ||
| Q2 25 | 12.4% | — | ||
| Q1 25 | 12.6% | — | ||
| Q4 24 | 5.7% | — | ||
| Q3 24 | 3.9% | — | ||
| Q2 24 | 1.4% | — | ||
| Q1 24 | 583.4% | — |
| Q4 25 | — | — | ||
| Q3 25 | — | 0.31× | ||
| Q2 25 | — | 1.16× | ||
| Q1 25 | — | -0.35× | ||
| Q4 24 | — | — | ||
| Q3 24 | — | -0.23× | ||
| Q2 24 | — | 1.11× | ||
| Q1 24 | — | 2.30× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
IOVA
| Amtagvi | $64.9M | 75% |
| Proleukin | $21.9M | 25% |
MFA
Segment breakdown not available.
