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Side-by-side financial comparison of IOVANCE BIOTHERAPEUTICS, INC. (IOVA) and Strategy Inc (MSTR). Click either name above to swap in a different company.

Strategy Inc is the larger business by last-quarter revenue ($123.0M vs $86.8M, roughly 1.4× IOVANCE BIOTHERAPEUTICS, INC.). On growth, IOVANCE BIOTHERAPEUTICS, INC. posted the faster year-over-year revenue change (17.7% vs 1.9%). Over the past eight quarters, IOVANCE BIOTHERAPEUTICS, INC.'s revenue compounded faster (1001.6% CAGR vs 3.3%).

Iovance Biotherapeutics, Inc. is a biopharmaceutical startup based in San Carlos, California. The company works to develop tumor-infiltrating lymphocyte (TIL) therapies against cancer.

Strategy Inc., formerly known as MicroStrategy, is an American company that provides business intelligence (BI) and mobile software. Founded in 1989 by Michael J. Saylor, Sanju Bansal, and Thomas Spahr, the firm develops software to analyze internal and external data in order to make business decisions and to develop mobile apps. It is a public company headquartered in Tysons Corner, Virginia, in the Washington metropolitan area. Its primary business analytics competitors include SAP SE Busin...

IOVA vs MSTR — Head-to-Head

Bigger by revenue
MSTR
MSTR
1.4× larger
MSTR
$123.0M
$86.8M
IOVA
Growing faster (revenue YoY)
IOVA
IOVA
+15.8% gap
IOVA
17.7%
1.9%
MSTR
Faster 2-yr revenue CAGR
IOVA
IOVA
Annualised
IOVA
1001.6%
3.3%
MSTR

Income Statement — Q4 FY2025 vs Q2 FY2026

Metric
IOVA
IOVA
MSTR
MSTR
Revenue
$86.8M
$123.0M
Net Profit
Gross Margin
67.4%
66.1%
Operating Margin
-84.7%
Net Margin
Revenue YoY
17.7%
1.9%
Net Profit YoY
EPS (diluted)

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
IOVA
IOVA
MSTR
MSTR
Q4 25
$86.8M
$123.0M
Q3 25
$67.5M
$128.7M
Q2 25
$60.0M
$114.5M
Q1 25
$49.3M
$111.1M
Q4 24
$73.7M
$120.7M
Q3 24
$58.6M
$116.1M
Q2 24
$31.1M
$111.4M
Q1 24
$715.0K
$115.2M
Net Profit
IOVA
IOVA
MSTR
MSTR
Q4 25
Q3 25
$-91.3M
$2.8B
Q2 25
$-111.7M
$10.0B
Q1 25
$-116.2M
$-4.2B
Q4 24
$-670.8M
Q3 24
$-83.5M
$-340.2M
Q2 24
$-97.1M
$-102.6M
Q1 24
$-113.0M
$-53.1M
Gross Margin
IOVA
IOVA
MSTR
MSTR
Q4 25
67.4%
66.1%
Q3 25
43.0%
70.5%
Q2 25
5.5%
68.8%
Q1 25
-0.8%
69.4%
Q4 24
68.7%
71.7%
Q3 24
46.2%
70.4%
Q2 24
-0.8%
72.2%
Q1 24
74.0%
Operating Margin
IOVA
IOVA
MSTR
MSTR
Q4 25
-84.7%
Q3 25
-140.7%
Q2 25
-189.8%
Q1 25
-245.8%
-5331.4%
Q4 24
-117.5%
-842.1%
Q3 24
-152.1%
-372.7%
Q2 24
-327.6%
-179.7%
Q1 24
-16464.6%
-176.8%
Net Margin
IOVA
IOVA
MSTR
MSTR
Q4 25
Q3 25
-135.3%
2164.1%
Q2 25
-186.2%
8752.7%
Q1 25
-235.5%
-3797.2%
Q4 24
-555.8%
Q3 24
-142.7%
-293.1%
Q2 24
-312.2%
-92.0%
Q1 24
-15800.8%
-46.1%
EPS (diluted)
IOVA
IOVA
MSTR
MSTR
Q4 25
Q3 25
$8.42
Q2 25
$-0.33
$32.60
Q1 25
$-0.36
$-16.49
Q4 24
$-0.24
$4.49
Q3 24
$-0.28
$-1.72
Q2 24
$-0.34
$-0.57
Q1 24
$-0.42
$-0.31

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
IOVA
IOVA
MSTR
MSTR
Cash + ST InvestmentsLiquidity on hand
$297.0M
$2.3B
Total DebtLower is stronger
$8.2B
Stockholders' EquityBook value
$698.6M
$44.1B
Total Assets
$913.2M
$61.6B
Debt / EquityLower = less leverage
0.19×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
IOVA
IOVA
MSTR
MSTR
Q4 25
$297.0M
$2.3B
Q3 25
$300.8M
$54.3M
Q2 25
$301.2M
$50.1M
Q1 25
$359.7M
$60.3M
Q4 24
$323.8M
$38.1M
Q3 24
$397.5M
$46.3M
Q2 24
$412.5M
$66.9M
Q1 24
$356.2M
$81.3M
Total Debt
IOVA
IOVA
MSTR
MSTR
Q4 25
$8.2B
Q3 25
$8.2B
Q2 25
$8.2B
Q1 25
$8.1B
Q4 24
$7.2B
Q3 24
$4.2B
Q2 24
$3.8B
Q1 24
$3.6B
Stockholders' Equity
IOVA
IOVA
MSTR
MSTR
Q4 25
$698.6M
$44.1B
Q3 25
$702.3M
$52.3B
Q2 25
$698.5M
$47.5B
Q1 25
$767.9M
$32.2B
Q4 24
$710.4M
$18.2B
Q3 24
$773.5M
$3.8B
Q2 24
$768.5M
$2.8B
Q1 24
$680.0M
$2.4B
Total Assets
IOVA
IOVA
MSTR
MSTR
Q4 25
$913.2M
$61.6B
Q3 25
$904.9M
$73.6B
Q2 25
$907.4M
$64.8B
Q1 25
$966.7M
$43.9B
Q4 24
$910.4M
$25.8B
Q3 24
$991.1M
$8.3B
Q2 24
$964.3M
$7.1B
Q1 24
$869.8M
$6.4B
Debt / Equity
IOVA
IOVA
MSTR
MSTR
Q4 25
0.19×
Q3 25
0.16×
Q2 25
0.17×
Q1 25
0.25×
Q4 24
0.39×
Q3 24
1.12×
Q2 24
1.36×
Q1 24
1.48×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
IOVA
IOVA
MSTR
MSTR
Operating Cash FlowLast quarter
$-52.6M
Free Cash FlowOCF − Capex
$-61.9M
FCF MarginFCF / Revenue
-71.3%
Capex IntensityCapex / Revenue
10.7%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-336.2M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
IOVA
IOVA
MSTR
MSTR
Q4 25
$-52.6M
Q3 25
$-78.7M
$-8.3M
Q2 25
$-67.4M
$-34.9M
Q1 25
$-103.7M
$-2.4M
Q4 24
$-73.3M
$-17.3M
Q3 24
$-59.0M
$-41.0M
Q2 24
$-98.4M
$-23.3M
Q1 24
$-122.3M
$28.6M
Free Cash Flow
IOVA
IOVA
MSTR
MSTR
Q4 25
$-61.9M
Q3 25
$-89.5M
$-11.1M
Q2 25
$-74.9M
$-37.0M
Q1 25
$-109.9M
$-5.1M
Q4 24
$-77.5M
$-17.6M
Q3 24
$-61.3M
$-41.4M
Q2 24
$-98.9M
$-24.1M
Q1 24
$-126.5M
$27.0M
FCF Margin
IOVA
IOVA
MSTR
MSTR
Q4 25
-71.3%
Q3 25
-132.7%
-8.6%
Q2 25
-124.9%
-32.3%
Q1 25
-222.8%
-4.6%
Q4 24
-105.1%
-14.6%
Q3 24
-104.6%
-35.7%
Q2 24
-317.9%
-21.6%
Q1 24
-17685.3%
23.5%
Capex Intensity
IOVA
IOVA
MSTR
MSTR
Q4 25
10.7%
Q3 25
16.1%
2.2%
Q2 25
12.4%
1.8%
Q1 25
12.6%
2.5%
Q4 24
5.7%
0.2%
Q3 24
3.9%
0.4%
Q2 24
1.4%
0.6%
Q1 24
583.4%
1.3%
Cash Conversion
IOVA
IOVA
MSTR
MSTR
Q4 25
Q3 25
-0.00×
Q2 25
-0.00×
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

IOVA
IOVA

Amtagvi$64.9M75%
Proleukin$21.9M25%

MSTR
MSTR

Segment breakdown not available.

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