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Side-by-side financial comparison of IOVANCE BIOTHERAPEUTICS, INC. (IOVA) and ThredUp Inc. (TDUP). Click either name above to swap in a different company.

IOVANCE BIOTHERAPEUTICS, INC. is the larger business by last-quarter revenue ($86.8M vs $79.7M, roughly 1.1× ThredUp Inc.). On growth, ThredUp Inc. posted the faster year-over-year revenue change (18.5% vs 17.7%). ThredUp Inc. produced more free cash flow last quarter ($-3.2M vs $-61.9M). Over the past eight quarters, IOVANCE BIOTHERAPEUTICS, INC.'s revenue compounded faster (1001.6% CAGR vs 11.1%).

Iovance Biotherapeutics, Inc. is a biopharmaceutical startup based in San Carlos, California. The company works to develop tumor-infiltrating lymphocyte (TIL) therapies against cancer.

ThredUp Inc. is an American company that operates an online resale platform specializing in the sale of second-hand clothing, footwear, and accessories. Founded in 2009 and headquartered in Oakland, California, it has established itself as one of the leading resale fashion marketplaces.

IOVA vs TDUP — Head-to-Head

Bigger by revenue
IOVA
IOVA
1.1× larger
IOVA
$86.8M
$79.7M
TDUP
Growing faster (revenue YoY)
TDUP
TDUP
+0.7% gap
TDUP
18.5%
17.7%
IOVA
More free cash flow
TDUP
TDUP
$58.7M more FCF
TDUP
$-3.2M
$-61.9M
IOVA
Faster 2-yr revenue CAGR
IOVA
IOVA
Annualised
IOVA
1001.6%
11.1%
TDUP

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
IOVA
IOVA
TDUP
TDUP
Revenue
$86.8M
$79.7M
Net Profit
$-5.6M
Gross Margin
67.4%
79.6%
Operating Margin
-84.7%
-8.4%
Net Margin
-7.0%
Revenue YoY
17.7%
18.5%
Net Profit YoY
74.3%
EPS (diluted)
$-0.06

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
IOVA
IOVA
TDUP
TDUP
Q4 25
$86.8M
$79.7M
Q3 25
$67.5M
$82.2M
Q2 25
$60.0M
$77.7M
Q1 25
$49.3M
$71.3M
Q4 24
$73.7M
$67.3M
Q3 24
$58.6M
$61.5M
Q2 24
$31.1M
$66.7M
Q1 24
$715.0K
$64.5M
Net Profit
IOVA
IOVA
TDUP
TDUP
Q4 25
$-5.6M
Q3 25
$-91.3M
$-4.2M
Q2 25
$-111.7M
$-5.2M
Q1 25
$-116.2M
$-5.2M
Q4 24
$-21.7M
Q3 24
$-83.5M
$-24.8M
Q2 24
$-97.1M
$-14.0M
Q1 24
$-113.0M
$-16.6M
Gross Margin
IOVA
IOVA
TDUP
TDUP
Q4 25
67.4%
79.6%
Q3 25
43.0%
79.4%
Q2 25
5.5%
79.5%
Q1 25
-0.8%
79.1%
Q4 24
68.7%
80.4%
Q3 24
46.2%
79.3%
Q2 24
-0.8%
78.8%
Q1 24
80.1%
Operating Margin
IOVA
IOVA
TDUP
TDUP
Q4 25
-84.7%
-8.4%
Q3 25
-140.7%
-5.3%
Q2 25
-189.8%
-6.8%
Q1 25
-245.8%
-7.6%
Q4 24
-117.5%
-12.1%
Q3 24
-152.1%
-17.0%
Q2 24
-327.6%
-14.4%
Q1 24
-16464.6%
-19.2%
Net Margin
IOVA
IOVA
TDUP
TDUP
Q4 25
-7.0%
Q3 25
-135.3%
-5.2%
Q2 25
-186.2%
-6.7%
Q1 25
-235.5%
-7.3%
Q4 24
-32.3%
Q3 24
-142.7%
-40.3%
Q2 24
-312.2%
-20.9%
Q1 24
-15800.8%
-25.7%
EPS (diluted)
IOVA
IOVA
TDUP
TDUP
Q4 25
$-0.06
Q3 25
$-0.03
Q2 25
$-0.33
$-0.04
Q1 25
$-0.36
$-0.04
Q4 24
$-0.24
$-0.19
Q3 24
$-0.28
$-0.22
Q2 24
$-0.34
$-0.13
Q1 24
$-0.42
$-0.15

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
IOVA
IOVA
TDUP
TDUP
Cash + ST InvestmentsLiquidity on hand
$297.0M
$38.6M
Total DebtLower is stronger
Stockholders' EquityBook value
$698.6M
$59.2M
Total Assets
$913.2M
$167.2M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
IOVA
IOVA
TDUP
TDUP
Q4 25
$297.0M
$38.6M
Q3 25
$300.8M
$46.2M
Q2 25
$301.2M
$41.0M
Q1 25
$359.7M
$41.1M
Q4 24
$323.8M
$31.9M
Q3 24
$397.5M
$43.7M
Q2 24
$412.5M
$44.8M
Q1 24
$356.2M
$50.1M
Stockholders' Equity
IOVA
IOVA
TDUP
TDUP
Q4 25
$698.6M
$59.2M
Q3 25
$702.3M
$59.1M
Q2 25
$698.5M
$60.2M
Q1 25
$767.9M
$56.1M
Q4 24
$710.4M
$56.3M
Q3 24
$773.5M
$69.3M
Q2 24
$768.5M
$86.5M
Q1 24
$680.0M
$93.5M
Total Assets
IOVA
IOVA
TDUP
TDUP
Q4 25
$913.2M
$167.2M
Q3 25
$904.9M
$172.5M
Q2 25
$907.4M
$173.6M
Q1 25
$966.7M
$172.5M
Q4 24
$910.4M
$171.2M
Q3 24
$991.1M
$214.9M
Q2 24
$964.3M
$231.2M
Q1 24
$869.8M
$244.3M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
IOVA
IOVA
TDUP
TDUP
Operating Cash FlowLast quarter
$-52.6M
$-1.5M
Free Cash FlowOCF − Capex
$-61.9M
$-3.2M
FCF MarginFCF / Revenue
-71.3%
-4.0%
Capex IntensityCapex / Revenue
10.7%
2.2%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-336.2M
$180.0K

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
IOVA
IOVA
TDUP
TDUP
Q4 25
$-52.6M
$-1.5M
Q3 25
$-78.7M
$6.0M
Q2 25
$-67.4M
$344.0K
Q1 25
$-103.7M
$5.7M
Q4 24
$-73.3M
$663.0K
Q3 24
$-59.0M
$3.3M
Q2 24
$-98.4M
$-5.0M
Q1 24
$-122.3M
$1.4M
Free Cash Flow
IOVA
IOVA
TDUP
TDUP
Q4 25
$-61.9M
$-3.2M
Q3 25
$-89.5M
$2.4M
Q2 25
$-74.9M
$-2.9M
Q1 25
$-109.9M
$3.9M
Q4 24
$-77.5M
$-1.8M
Q3 24
$-61.3M
$1.2M
Q2 24
$-98.9M
$-5.8M
Q1 24
$-126.5M
$267.0K
FCF Margin
IOVA
IOVA
TDUP
TDUP
Q4 25
-71.3%
-4.0%
Q3 25
-132.7%
2.9%
Q2 25
-124.9%
-3.8%
Q1 25
-222.8%
5.5%
Q4 24
-105.1%
-2.7%
Q3 24
-104.6%
2.0%
Q2 24
-317.9%
-8.7%
Q1 24
-17685.3%
0.4%
Capex Intensity
IOVA
IOVA
TDUP
TDUP
Q4 25
10.7%
2.2%
Q3 25
16.1%
4.4%
Q2 25
12.4%
4.2%
Q1 25
12.6%
2.5%
Q4 24
5.7%
3.7%
Q3 24
3.9%
3.5%
Q2 24
1.4%
1.3%
Q1 24
583.4%
1.7%

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

IOVA
IOVA

Amtagvi$64.9M75%
Proleukin$21.9M25%

TDUP
TDUP

Segment breakdown not available.

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