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Side-by-side financial comparison of IQVIA (IQV) and Norfolk Southern (NSC). Click either name above to swap in a different company.

IQVIA is the larger business by last-quarter revenue ($4.4B vs $3.0B, roughly 1.5× Norfolk Southern). Norfolk Southern runs the higher net margin — 21.7% vs 11.8%, a 9.9% gap on every dollar of revenue. On growth, IQVIA posted the faster year-over-year revenue change (10.3% vs -1.7%). IQVIA produced more free cash flow last quarter ($561.0M vs $334.0M). Over the past eight quarters, IQVIA's revenue compounded faster (8.1% CAGR vs -0.5%).

IQVIA Holdings, Inc., headquartered in Durham, North Carolina, is an American company focused on health information technology and clinical research.

The Norfolk Southern Railway is a Class I freight railroad operating in the Eastern United States. Headquartered in Atlanta, the company was formed in 1982 with the merger of the Norfolk and Western Railway and Southern Railway. The company operates 19,420 route miles (31,250 km) in 22 eastern states and the District of Columbia, and has rights in Canada over the Albany to Montreal route of the Canadian Pacific Kansas City.

IQV vs NSC — Head-to-Head

Bigger by revenue
IQV
IQV
1.5× larger
IQV
$4.4B
$3.0B
NSC
Growing faster (revenue YoY)
IQV
IQV
+11.9% gap
IQV
10.3%
-1.7%
NSC
Higher net margin
NSC
NSC
9.9% more per $
NSC
21.7%
11.8%
IQV
More free cash flow
IQV
IQV
$227.0M more FCF
IQV
$561.0M
$334.0M
NSC
Faster 2-yr revenue CAGR
IQV
IQV
Annualised
IQV
8.1%
-0.5%
NSC

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
IQV
IQV
NSC
NSC
Revenue
$4.4B
$3.0B
Net Profit
$514.0M
$644.0M
Gross Margin
Operating Margin
14.4%
31.5%
Net Margin
11.8%
21.7%
Revenue YoY
10.3%
-1.7%
Net Profit YoY
17.6%
-12.1%
EPS (diluted)
$2.97
$2.87

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
IQV
IQV
NSC
NSC
Q4 25
$4.4B
$3.0B
Q3 25
$4.1B
$3.1B
Q2 25
$4.0B
$3.1B
Q1 25
$3.8B
$3.0B
Q4 24
$4.0B
$3.0B
Q3 24
$3.9B
$3.1B
Q2 24
$3.8B
$3.0B
Q1 24
$3.7B
$3.0B
Net Profit
IQV
IQV
NSC
NSC
Q4 25
$514.0M
$644.0M
Q3 25
$331.0M
$711.0M
Q2 25
$266.0M
$768.0M
Q1 25
$249.0M
$750.0M
Q4 24
$437.0M
$733.0M
Q3 24
$285.0M
$1.1B
Q2 24
$363.0M
$737.0M
Q1 24
$288.0M
$53.0M
Gross Margin
IQV
IQV
NSC
NSC
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
23.5%
Q2 24
22.6%
Q1 24
22.1%
Operating Margin
IQV
IQV
NSC
NSC
Q4 25
14.4%
31.5%
Q3 25
13.5%
35.4%
Q2 25
12.6%
37.8%
Q1 25
13.0%
38.3%
Q4 24
15.8%
37.4%
Q3 24
14.1%
52.3%
Q2 24
13.6%
37.2%
Q1 24
13.5%
7.1%
Net Margin
IQV
IQV
NSC
NSC
Q4 25
11.8%
21.7%
Q3 25
8.1%
22.9%
Q2 25
6.6%
24.7%
Q1 25
6.5%
25.1%
Q4 24
11.0%
24.2%
Q3 24
7.3%
36.0%
Q2 24
9.5%
24.2%
Q1 24
7.7%
1.8%
EPS (diluted)
IQV
IQV
NSC
NSC
Q4 25
$2.97
$2.87
Q3 25
$1.93
$3.16
Q2 25
$1.54
$3.41
Q1 25
$1.40
$3.31
Q4 24
$2.41
$3.24
Q3 24
$1.55
$4.85
Q2 24
$1.97
$3.25
Q1 24
$1.56
$0.23

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
IQV
IQV
NSC
NSC
Cash + ST InvestmentsLiquidity on hand
$2.1B
$1.5B
Total DebtLower is stronger
$16.5B
Stockholders' EquityBook value
$6.5B
$15.5B
Total Assets
$29.9B
$45.2B
Debt / EquityLower = less leverage
1.06×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
IQV
IQV
NSC
NSC
Q4 25
$2.1B
$1.5B
Q3 25
$2.0B
$1.4B
Q2 25
$2.2B
$1.3B
Q1 25
$1.9B
$1.0B
Q4 24
$1.8B
$1.6B
Q3 24
$1.7B
$975.0M
Q2 24
$1.7B
$659.0M
Q1 24
$1.6B
$652.0M
Total Debt
IQV
IQV
NSC
NSC
Q4 25
$16.5B
Q3 25
$16.5B
Q2 25
$16.5B
Q1 25
$16.7B
Q4 24
$16.7B
Q3 24
$16.6B
Q2 24
$16.9B
Q1 24
$17.2B
Stockholders' Equity
IQV
IQV
NSC
NSC
Q4 25
$6.5B
$15.5B
Q3 25
$6.2B
$15.1B
Q2 25
$5.8B
$14.8B
Q1 25
$6.0B
$14.5B
Q4 24
$6.1B
$14.3B
Q3 24
$7.0B
$13.8B
Q2 24
$6.7B
$13.0B
Q1 24
$6.3B
$12.5B
Total Assets
IQV
IQV
NSC
NSC
Q4 25
$29.9B
$45.2B
Q3 25
$28.7B
$44.6B
Q2 25
$28.6B
$44.2B
Q1 25
$27.3B
$43.8B
Q4 24
$26.9B
$43.7B
Q3 24
$27.2B
$43.3B
Q2 24
$26.4B
$42.6B
Q1 24
$26.6B
$42.1B
Debt / Equity
IQV
IQV
NSC
NSC
Q4 25
1.06×
Q3 25
1.09×
Q2 25
1.11×
Q1 25
1.15×
Q4 24
1.16×
Q3 24
1.21×
Q2 24
1.30×
Q1 24
1.37×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
IQV
IQV
NSC
NSC
Operating Cash FlowLast quarter
$735.0M
$1.1B
Free Cash FlowOCF − Capex
$561.0M
$334.0M
FCF MarginFCF / Revenue
12.9%
11.2%
Capex IntensityCapex / Revenue
4.0%
24.5%
Cash ConversionOCF / Net Profit
1.43×
1.65×
TTM Free Cash FlowTrailing 4 quarters
$2.1B
$2.2B

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
IQV
IQV
NSC
NSC
Q4 25
$735.0M
$1.1B
Q3 25
$908.0M
$1.3B
Q2 25
$443.0M
$1.1B
Q1 25
$568.0M
$950.0M
Q4 24
$885.0M
$951.0M
Q3 24
$721.0M
$1.2B
Q2 24
$588.0M
$1.0B
Q1 24
$522.0M
$839.0M
Free Cash Flow
IQV
IQV
NSC
NSC
Q4 25
$561.0M
$334.0M
Q3 25
$772.0M
$720.0M
Q2 25
$292.0M
$602.0M
Q1 25
$426.0M
$501.0M
Q4 24
$721.0M
$276.0M
Q3 24
$571.0M
$645.0M
Q2 24
$445.0M
$468.0M
Q1 24
$377.0M
$282.0M
FCF Margin
IQV
IQV
NSC
NSC
Q4 25
12.9%
11.2%
Q3 25
18.8%
23.2%
Q2 25
7.3%
19.4%
Q1 25
11.1%
16.7%
Q4 24
18.2%
9.1%
Q3 24
14.7%
21.1%
Q2 24
11.7%
15.4%
Q1 24
10.1%
9.4%
Capex Intensity
IQV
IQV
NSC
NSC
Q4 25
4.0%
24.5%
Q3 25
3.3%
17.8%
Q2 25
3.8%
15.3%
Q1 25
3.7%
15.0%
Q4 24
4.1%
22.3%
Q3 24
3.9%
19.0%
Q2 24
3.7%
18.7%
Q1 24
3.9%
18.5%
Cash Conversion
IQV
IQV
NSC
NSC
Q4 25
1.43×
1.65×
Q3 25
2.74×
1.79×
Q2 25
1.67×
1.40×
Q1 25
2.28×
1.27×
Q4 24
2.03×
1.30×
Q3 24
2.53×
1.12×
Q2 24
1.62×
1.41×
Q1 24
1.81×
15.83×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

IQV
IQV

Segment breakdown not available.

NSC
NSC

Railway Operating Revenues Market Group Merchandise$1.9B63%
Metals And Construction$404.0M14%
Railway Operating Revenues Market Group Coal$347.0M12%
Automotive$293.0M10%

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