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Side-by-side financial comparison of Ingersoll Rand (IR) and Vertex Pharmaceuticals (VRTX). Click either name above to swap in a different company.

Vertex Pharmaceuticals is the larger business by last-quarter revenue ($3.0B vs $2.1B, roughly 1.4× Ingersoll Rand). Vertex Pharmaceuticals runs the higher net margin — 34.5% vs 12.7%, a 21.8% gap on every dollar of revenue. On growth, Ingersoll Rand posted the faster year-over-year revenue change (10.1% vs 7.8%). Over the past eight quarters, Ingersoll Rand's revenue compounded faster (11.9% CAGR vs 6.3%).

Ingersoll Rand Inc. is an American multinational company that provides flow creation and industrial products. The company was formed in February 2020 through the spinoff of the industrial segment of Ingersoll-Rand plc and its merger with Gardner Denver. Its products are sold under more than 40 brands across all major global markets.

Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, Oxfordshire, England.

IR vs VRTX — Head-to-Head

Bigger by revenue
VRTX
VRTX
1.4× larger
VRTX
$3.0B
$2.1B
IR
Growing faster (revenue YoY)
IR
IR
+2.3% gap
IR
10.1%
7.8%
VRTX
Higher net margin
VRTX
VRTX
21.8% more per $
VRTX
34.5%
12.7%
IR
Faster 2-yr revenue CAGR
IR
IR
Annualised
IR
11.9%
6.3%
VRTX

Income Statement — Q4 FY2025 vs Q1 FY2026

Metric
IR
IR
VRTX
VRTX
Revenue
$2.1B
$3.0B
Net Profit
$266.1M
$1.0B
Gross Margin
42.6%
86.8%
Operating Margin
18.7%
38.1%
Net Margin
12.7%
34.5%
Revenue YoY
10.1%
7.8%
Net Profit YoY
15.8%
59.6%
EPS (diluted)
$0.67
$4.02

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
IR
IR
VRTX
VRTX
Q1 26
$3.0B
Q4 25
$2.1B
$3.2B
Q3 25
$2.0B
$3.1B
Q2 25
$1.9B
$3.0B
Q1 25
$1.7B
$2.8B
Q4 24
$1.9B
$2.9B
Q3 24
$1.9B
$2.8B
Q2 24
$1.8B
$2.6B
Net Profit
IR
IR
VRTX
VRTX
Q1 26
$1.0B
Q4 25
$266.1M
$1.2B
Q3 25
$244.1M
$1.1B
Q2 25
$-115.3M
$1.0B
Q1 25
$186.5M
$646.3M
Q4 24
$229.8M
$913.0M
Q3 24
$221.6M
$1.0B
Q2 24
$185.0M
$-3.6B
Gross Margin
IR
IR
VRTX
VRTX
Q1 26
86.8%
Q4 25
42.6%
85.4%
Q3 25
43.7%
86.5%
Q2 25
43.7%
86.3%
Q1 25
44.6%
86.9%
Q4 24
42.9%
85.5%
Q3 24
43.8%
85.8%
Q2 24
43.9%
85.9%
Operating Margin
IR
IR
VRTX
VRTX
Q1 26
38.1%
Q4 25
18.7%
37.8%
Q3 25
19.2%
38.6%
Q2 25
4.0%
38.8%
Q1 25
17.6%
22.7%
Q4 24
20.0%
35.2%
Q3 24
19.1%
40.3%
Q2 24
15.1%
-132.9%
Net Margin
IR
IR
VRTX
VRTX
Q1 26
34.5%
Q4 25
12.7%
37.3%
Q3 25
12.5%
35.2%
Q2 25
-6.1%
34.8%
Q1 25
10.9%
23.3%
Q4 24
12.1%
31.4%
Q3 24
11.9%
37.7%
Q2 24
10.2%
-135.8%
EPS (diluted)
IR
IR
VRTX
VRTX
Q1 26
$4.02
Q4 25
$0.67
$4.64
Q3 25
$0.61
$4.20
Q2 25
$-0.29
$3.99
Q1 25
$0.46
$2.49
Q4 24
$0.57
$3.62
Q3 24
$0.54
$4.01
Q2 24
$0.45
$-13.92

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
IR
IR
VRTX
VRTX
Cash + ST InvestmentsLiquidity on hand
$1.2B
Total DebtLower is stronger
$4.8B
Stockholders' EquityBook value
$10.1B
$19.4B
Total Assets
$18.3B
$26.5B
Debt / EquityLower = less leverage
0.47×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
IR
IR
VRTX
VRTX
Q1 26
Q4 25
$1.2B
$6.6B
Q3 25
$1.2B
$6.3B
Q2 25
$1.3B
$6.4B
Q1 25
$1.6B
$6.2B
Q4 24
$1.5B
$6.1B
Q3 24
$1.4B
$6.5B
Q2 24
$1.1B
$5.8B
Total Debt
IR
IR
VRTX
VRTX
Q1 26
Q4 25
$4.8B
Q3 25
$4.8B
Q2 25
$4.8B
Q1 25
$4.8B
Q4 24
$4.8B
Q3 24
$4.8B
Q2 24
$4.8B
Stockholders' Equity
IR
IR
VRTX
VRTX
Q1 26
$19.4B
Q4 25
$10.1B
$18.7B
Q3 25
$10.1B
$17.3B
Q2 25
$10.1B
$17.2B
Q1 25
$10.5B
$16.5B
Q4 24
$10.2B
$16.4B
Q3 24
$10.3B
$15.6B
Q2 24
$10.0B
$14.8B
Total Assets
IR
IR
VRTX
VRTX
Q1 26
$26.5B
Q4 25
$18.3B
$25.6B
Q3 25
$18.2B
$24.9B
Q2 25
$18.1B
$24.0B
Q1 25
$18.4B
$22.9B
Q4 24
$18.0B
$22.5B
Q3 24
$18.2B
$22.2B
Q2 24
$17.8B
$20.1B
Debt / Equity
IR
IR
VRTX
VRTX
Q1 26
Q4 25
0.47×
Q3 25
0.47×
Q2 25
0.47×
Q1 25
0.45×
Q4 24
0.47×
Q3 24
0.47×
Q2 24
0.48×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
IR
IR
VRTX
VRTX
Operating Cash FlowLast quarter
$499.0M
Free Cash FlowOCF − Capex
$461.5M
FCF MarginFCF / Revenue
22.1%
Capex IntensityCapex / Revenue
1.8%
Cash ConversionOCF / Net Profit
1.88×
TTM Free Cash FlowTrailing 4 quarters
$1.2B

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
IR
IR
VRTX
VRTX
Q1 26
Q4 25
$499.0M
$498.0M
Q3 25
$354.6M
$1.2B
Q2 25
$245.7M
$1.1B
Q1 25
$256.4M
$818.9M
Q4 24
$526.2M
$584.6M
Q3 24
$404.0M
$1.4B
Q2 24
$304.9M
$-3.8B
Free Cash Flow
IR
IR
VRTX
VRTX
Q1 26
Q4 25
$461.5M
$348.6M
Q3 25
$325.5M
$1.1B
Q2 25
$210.4M
$927.4M
Q1 25
$222.7M
$778.2M
Q4 24
$490.9M
$492.0M
Q3 24
$374.3M
$1.3B
Q2 24
$283.1M
$-3.8B
FCF Margin
IR
IR
VRTX
VRTX
Q1 26
Q4 25
22.1%
10.9%
Q3 25
16.6%
37.0%
Q2 25
11.1%
31.3%
Q1 25
13.0%
28.1%
Q4 24
25.9%
16.9%
Q3 24
20.1%
47.0%
Q2 24
15.7%
-144.5%
Capex Intensity
IR
IR
VRTX
VRTX
Q1 26
Q4 25
1.8%
4.7%
Q3 25
1.5%
3.3%
Q2 25
1.9%
4.9%
Q1 25
2.0%
1.5%
Q4 24
1.9%
3.2%
Q3 24
1.6%
2.4%
Q2 24
1.2%
2.6%
Cash Conversion
IR
IR
VRTX
VRTX
Q1 26
Q4 25
1.88×
0.42×
Q3 25
1.45×
1.15×
Q2 25
1.04×
Q1 25
1.37×
1.27×
Q4 24
2.29×
0.64×
Q3 24
1.82×
1.31×
Q2 24
1.65×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

IR
IR

Transferred At Point In Time$1.5B71%
Transferred Over Time$193.0M9%
Precision And Science Technologies Segment$183.1M9%
Acquisitions In2024$175.6M8%
Acquisitions In2025$70.8M3%

VRTX
VRTX

TRIKAFTA/KAFTRIO$2.4B79%
ALYFTREK$424.4M14%
Other$135.9M5%
CASGEVY$42.9M1%
Vertex recorded$29.0M1%

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