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Side-by-side financial comparison of iRhythm Holdings, Inc. (IRTC) and Penumbra Inc (PEN). Click either name above to swap in a different company.

Penumbra Inc is the larger business by last-quarter revenue ($385.4M vs $208.9M, roughly 1.8× iRhythm Holdings, Inc.). Penumbra Inc runs the higher net margin — 12.3% vs 2.7%, a 9.6% gap on every dollar of revenue. On growth, iRhythm Holdings, Inc. posted the faster year-over-year revenue change (27.1% vs 22.1%). Penumbra Inc produced more free cash flow last quarter ($68.0M vs $14.5M). Over the past eight quarters, iRhythm Holdings, Inc.'s revenue compounded faster (25.8% CAGR vs 17.6%).

iRhythm Holdings is a digital healthcare company focused on cardiac care, developing and commercializing wearable ambulatory heart monitoring devices paired with AI-powered analytical tools. It primarily serves healthcare providers and patients across the United States, helping to detect undiagnosed arrhythmias such as atrial fibrillation through convenient long-term heart rhythm tracking that delivers actionable clinical insights.

Penumbra, Inc. is an American medical device company headquartered in Alameda, California. The company was founded by Arani Bose and Adam Elsesser in 2004. It manufactures devices for interventional therapies to treat vascular conditions such as stroke and aneurysm.

IRTC vs PEN — Head-to-Head

Bigger by revenue
PEN
PEN
1.8× larger
PEN
$385.4M
$208.9M
IRTC
Growing faster (revenue YoY)
IRTC
IRTC
+5.0% gap
IRTC
27.1%
22.1%
PEN
Higher net margin
PEN
PEN
9.6% more per $
PEN
12.3%
2.7%
IRTC
More free cash flow
PEN
PEN
$53.6M more FCF
PEN
$68.0M
$14.5M
IRTC
Faster 2-yr revenue CAGR
IRTC
IRTC
Annualised
IRTC
25.8%
17.6%
PEN

Income Statement — Q4 2025 vs Q4 2025

Metric
IRTC
IRTC
PEN
PEN
Revenue
$208.9M
$385.4M
Net Profit
$5.6M
$47.3M
Gross Margin
70.9%
68.0%
Operating Margin
1.1%
15.4%
Net Margin
2.7%
12.3%
Revenue YoY
27.1%
22.1%
Net Profit YoY
518.5%
40.6%
EPS (diluted)
$0.18
$1.20

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
IRTC
IRTC
PEN
PEN
Q4 25
$208.9M
$385.4M
Q3 25
$192.9M
$354.7M
Q2 25
$186.7M
$339.5M
Q1 25
$158.7M
$324.1M
Q4 24
$164.3M
$315.5M
Q3 24
$147.5M
$301.0M
Q2 24
$148.0M
$299.4M
Q1 24
$131.9M
$278.7M
Net Profit
IRTC
IRTC
PEN
PEN
Q4 25
$5.6M
$47.3M
Q3 25
$-5.2M
$45.9M
Q2 25
$-14.2M
$45.3M
Q1 25
$-30.7M
$39.2M
Q4 24
$-1.3M
$33.7M
Q3 24
$-46.2M
$29.5M
Q2 24
$-20.1M
$-60.2M
Q1 24
$-45.7M
$11.0M
Gross Margin
IRTC
IRTC
PEN
PEN
Q4 25
70.9%
68.0%
Q3 25
71.1%
67.8%
Q2 25
71.2%
66.0%
Q1 25
68.8%
66.6%
Q4 24
70.0%
66.8%
Q3 24
68.8%
66.5%
Q2 24
69.9%
54.4%
Q1 24
66.3%
65.0%
Operating Margin
IRTC
IRTC
PEN
PEN
Q4 25
1.1%
15.4%
Q3 25
-4.4%
13.8%
Q2 25
-10.0%
12.0%
Q1 25
-20.5%
12.4%
Q4 24
-2.5%
13.6%
Q3 24
-34.1%
11.7%
Q2 24
-15.5%
-27.0%
Q1 24
-28.9%
4.3%
Net Margin
IRTC
IRTC
PEN
PEN
Q4 25
2.7%
12.3%
Q3 25
-2.7%
12.9%
Q2 25
-7.6%
13.3%
Q1 25
-19.3%
12.1%
Q4 24
-0.8%
10.7%
Q3 24
-31.3%
9.8%
Q2 24
-13.6%
-20.1%
Q1 24
-34.6%
3.9%
EPS (diluted)
IRTC
IRTC
PEN
PEN
Q4 25
$0.18
$1.20
Q3 25
$-0.16
$1.17
Q2 25
$-0.44
$1.15
Q1 25
$-0.97
$1.00
Q4 24
$-0.03
$0.88
Q3 24
$-1.48
$0.75
Q2 24
$-0.65
$-1.55
Q1 24
$-1.47
$0.28

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
IRTC
IRTC
PEN
PEN
Cash + ST InvestmentsLiquidity on hand
$583.8M
$186.9M
Total DebtLower is stronger
Stockholders' EquityBook value
$152.7M
$1.4B
Total Assets
$1.0B
$1.8B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
IRTC
IRTC
PEN
PEN
Q4 25
$583.8M
$186.9M
Q3 25
$565.2M
$321.0M
Q2 25
$545.5M
$421.8M
Q1 25
$520.6M
$376.1M
Q4 24
$535.6M
$324.4M
Q3 24
$522.0M
$280.5M
Q2 24
$561.5M
$288.3M
Q1 24
$569.1M
$223.1M
Stockholders' Equity
IRTC
IRTC
PEN
PEN
Q4 25
$152.7M
$1.4B
Q3 25
$121.9M
$1.4B
Q2 25
$103.7M
$1.3B
Q1 25
$86.7M
$1.2B
Q4 24
$90.9M
$1.2B
Q3 24
$71.8M
$1.1B
Q2 24
$99.2M
$1.2B
Q1 24
$90.3M
$1.2B
Total Assets
IRTC
IRTC
PEN
PEN
Q4 25
$1.0B
$1.8B
Q3 25
$995.2M
$1.7B
Q2 25
$964.0M
$1.7B
Q1 25
$926.1M
$1.6B
Q4 24
$931.4M
$1.5B
Q3 24
$909.7M
$1.5B
Q2 24
$919.2M
$1.5B
Q1 24
$909.8M
$1.6B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
IRTC
IRTC
PEN
PEN
Operating Cash FlowLast quarter
$26.2M
$86.5M
Free Cash FlowOCF − Capex
$14.5M
$68.0M
FCF MarginFCF / Revenue
6.9%
17.7%
Capex IntensityCapex / Revenue
5.6%
4.8%
Cash ConversionOCF / Net Profit
4.70×
1.83×
TTM Free Cash FlowTrailing 4 quarters
$34.5M
$174.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
IRTC
IRTC
PEN
PEN
Q4 25
$26.2M
$86.5M
Q3 25
$34.9M
$58.3M
Q2 25
$27.7M
$44.9M
Q1 25
$-7.9M
$49.0M
Q4 24
$19.2M
$51.1M
Q3 24
$24.3M
$56.5M
Q2 24
$11.8M
$22.6M
Q1 24
$-52.0M
$38.3M
Free Cash Flow
IRTC
IRTC
PEN
PEN
Q4 25
$14.5M
$68.0M
Q3 25
$20.1M
$42.0M
Q2 25
$17.3M
$29.4M
Q1 25
$-17.3M
$35.5M
Q4 24
$12.4M
$45.7M
Q3 24
$15.5M
$51.0M
Q2 24
$3.4M
$18.1M
Q1 24
$-61.8M
$32.5M
FCF Margin
IRTC
IRTC
PEN
PEN
Q4 25
6.9%
17.7%
Q3 25
10.4%
11.8%
Q2 25
9.3%
8.7%
Q1 25
-10.9%
11.0%
Q4 24
7.5%
14.5%
Q3 24
10.5%
16.9%
Q2 24
2.3%
6.0%
Q1 24
-46.8%
11.7%
Capex Intensity
IRTC
IRTC
PEN
PEN
Q4 25
5.6%
4.8%
Q3 25
7.7%
4.6%
Q2 25
5.6%
4.6%
Q1 25
5.9%
4.2%
Q4 24
4.2%
1.7%
Q3 24
6.0%
1.8%
Q2 24
5.7%
1.5%
Q1 24
7.4%
2.1%
Cash Conversion
IRTC
IRTC
PEN
PEN
Q4 25
4.70×
1.83×
Q3 25
1.27×
Q2 25
0.99×
Q1 25
1.25×
Q4 24
1.52×
Q3 24
1.91×
Q2 24
Q1 24
3.48×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

IRTC
IRTC

Commercial Payors$111.7M53%
Centers For Medicare And Medicaid$49.2M24%
Healthcare Institutions$34.3M16%
Non Contracted Third Party Payors$13.7M7%

PEN
PEN

Segment breakdown not available.

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