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Side-by-side financial comparison of IRONWOOD PHARMACEUTICALS INC (IRWD) and LUXFER HOLDINGS PLC (LXFR). Click either name above to swap in a different company.

LUXFER HOLDINGS PLC is the larger business by last-quarter revenue ($90.7M vs $47.7M, roughly 1.9× IRONWOOD PHARMACEUTICALS INC). LUXFER HOLDINGS PLC runs the higher net margin — -3.4% vs -4.8%, a 1.4% gap on every dollar of revenue. On growth, LUXFER HOLDINGS PLC posted the faster year-over-year revenue change (-12.3% vs -47.3%). IRONWOOD PHARMACEUTICALS INC produced more free cash flow last quarter ($74.6M vs $12.4M). Over the past eight quarters, LUXFER HOLDINGS PLC's revenue compounded faster (0.7% CAGR vs -20.2%).

Ironwood Pharmaceuticals, Inc. is a publicly traded pharmaceutical company. It was originally called Microbia, Inc.

Luxfer Holdings PLC is a global industrial manufacturer specializing in high-performance engineering materials and components. Its core products include lightweight aluminum and composite gas containment systems, advanced alloys, and specialty materials, serving key sectors such as aerospace, healthcare, automotive, industrial manufacturing, and alternative energy worldwide.

IRWD vs LXFR — Head-to-Head

Bigger by revenue
LXFR
LXFR
1.9× larger
LXFR
$90.7M
$47.7M
IRWD
Growing faster (revenue YoY)
LXFR
LXFR
+35.0% gap
LXFR
-12.3%
-47.3%
IRWD
Higher net margin
LXFR
LXFR
1.4% more per $
LXFR
-3.4%
-4.8%
IRWD
More free cash flow
IRWD
IRWD
$62.2M more FCF
IRWD
$74.6M
$12.4M
LXFR
Faster 2-yr revenue CAGR
LXFR
LXFR
Annualised
LXFR
0.7%
-20.2%
IRWD

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
IRWD
IRWD
LXFR
LXFR
Revenue
$47.7M
$90.7M
Net Profit
$-2.3M
$-3.1M
Gross Margin
24.4%
Operating Margin
14.3%
3.6%
Net Margin
-4.8%
-3.4%
Revenue YoY
-47.3%
-12.3%
Net Profit YoY
-200.9%
-188.6%
EPS (diluted)
$0.01
$-0.12

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
IRWD
IRWD
LXFR
LXFR
Q4 25
$47.7M
$90.7M
Q3 25
$122.1M
$92.9M
Q2 25
$85.2M
$104.0M
Q1 25
$41.1M
$97.0M
Q4 24
$90.5M
$103.4M
Q3 24
$91.6M
$99.4M
Q2 24
$94.4M
$99.7M
Q1 24
$74.9M
$89.4M
Net Profit
IRWD
IRWD
LXFR
LXFR
Q4 25
$-2.3M
$-3.1M
Q3 25
$40.1M
$2.7M
Q2 25
$23.6M
$2.6M
Q1 25
$-37.4M
$5.5M
Q4 24
$2.3M
$3.5M
Q3 24
$3.6M
$12.7M
Q2 24
$-860.0K
$-500.0K
Q1 24
$-4.2M
$2.7M
Gross Margin
IRWD
IRWD
LXFR
LXFR
Q4 25
24.4%
Q3 25
23.4%
Q2 25
23.1%
Q1 25
22.1%
Q4 24
22.1%
Q3 24
22.5%
Q2 24
22.1%
Q1 24
20.6%
Operating Margin
IRWD
IRWD
LXFR
LXFR
Q4 25
14.3%
3.6%
Q3 25
61.8%
5.8%
Q2 25
53.2%
7.4%
Q1 25
-70.7%
7.8%
Q4 24
34.8%
3.9%
Q3 24
28.0%
17.5%
Q2 24
26.5%
3.8%
Q1 24
14.7%
5.5%
Net Margin
IRWD
IRWD
LXFR
LXFR
Q4 25
-4.8%
-3.4%
Q3 25
32.8%
2.9%
Q2 25
27.7%
2.5%
Q1 25
-90.9%
5.7%
Q4 24
2.5%
3.4%
Q3 24
4.0%
12.8%
Q2 24
-0.9%
-0.5%
Q1 24
-5.6%
3.0%
EPS (diluted)
IRWD
IRWD
LXFR
LXFR
Q4 25
$0.01
$-0.12
Q3 25
$0.23
$0.10
Q2 25
$0.14
$0.10
Q1 25
$-0.23
$0.20
Q4 24
$0.03
$0.13
Q3 24
$0.02
$0.47
Q2 24
$-0.01
$-0.02
Q1 24
$-0.03
$0.10

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
IRWD
IRWD
LXFR
LXFR
Cash + ST InvestmentsLiquidity on hand
$215.5M
$8.3M
Total DebtLower is stronger
$39.4M
Stockholders' EquityBook value
$-261.8M
$226.4M
Total Assets
$396.9M
$369.7M
Debt / EquityLower = less leverage
0.17×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
IRWD
IRWD
LXFR
LXFR
Q4 25
$215.5M
$8.3M
Q3 25
$140.4M
$6.0M
Q2 25
$92.9M
$4.4M
Q1 25
$108.5M
$4.1M
Q4 24
$88.6M
$4.1M
Q3 24
$88.2M
$3.5M
Q2 24
$105.5M
$4.3M
Q1 24
$121.5M
$6.8M
Total Debt
IRWD
IRWD
LXFR
LXFR
Q4 25
$39.4M
Q3 25
$199.5M
$43.3M
Q2 25
$199.3M
$52.6M
Q1 25
$199.2M
$46.0M
Q4 24
$199.0M
$45.1M
Q3 24
$198.8M
$69.5M
Q2 24
$198.6M
$74.2M
Q1 24
$398.3M
$78.4M
Stockholders' Equity
IRWD
IRWD
LXFR
LXFR
Q4 25
$-261.8M
$226.4M
Q3 25
$-264.2M
$231.6M
Q2 25
$-308.2M
$237.7M
Q1 25
$-334.1M
$226.7M
Q4 24
$-301.3M
$219.5M
Q3 24
$-311.3M
$225.1M
Q2 24
$-321.7M
$206.3M
Q1 24
$-330.5M
$210.3M
Total Assets
IRWD
IRWD
LXFR
LXFR
Q4 25
$396.9M
$369.7M
Q3 25
$396.1M
$377.4M
Q2 25
$342.9M
$399.2M
Q1 25
$327.2M
$385.2M
Q4 24
$350.9M
$382.4M
Q3 24
$389.5M
$404.8M
Q2 24
$395.6M
$379.8M
Q1 24
$438.8M
$386.0M
Debt / Equity
IRWD
IRWD
LXFR
LXFR
Q4 25
0.17×
Q3 25
0.19×
Q2 25
0.22×
Q1 25
0.20×
Q4 24
0.21×
Q3 24
0.31×
Q2 24
0.36×
Q1 24
0.37×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
IRWD
IRWD
LXFR
LXFR
Operating Cash FlowLast quarter
$74.6M
$15.6M
Free Cash FlowOCF − Capex
$74.6M
$12.4M
FCF MarginFCF / Revenue
156.3%
13.7%
Capex IntensityCapex / Revenue
0.0%
3.5%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$127.0M
$26.2M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
IRWD
IRWD
LXFR
LXFR
Q4 25
$74.6M
$15.6M
Q3 25
$47.6M
$11.8M
Q2 25
$-15.1M
$1.2M
Q1 25
$20.0M
$5.4M
Q4 24
$15.2M
$25.5M
Q3 24
$9.9M
$13.0M
Q2 24
$33.5M
$8.9M
Q1 24
$45.0M
$3.7M
Free Cash Flow
IRWD
IRWD
LXFR
LXFR
Q4 25
$74.6M
$12.4M
Q3 25
$47.6M
$10.3M
Q2 25
$-15.1M
$-700.0K
Q1 25
$19.9M
$4.2M
Q4 24
$22.5M
Q3 24
$9.9M
$9.8M
Q2 24
$33.4M
$6.2M
Q1 24
$44.9M
$2.3M
FCF Margin
IRWD
IRWD
LXFR
LXFR
Q4 25
156.3%
13.7%
Q3 25
39.0%
11.1%
Q2 25
-17.7%
-0.7%
Q1 25
48.4%
4.3%
Q4 24
21.8%
Q3 24
10.8%
9.9%
Q2 24
35.4%
6.2%
Q1 24
60.0%
2.6%
Capex Intensity
IRWD
IRWD
LXFR
LXFR
Q4 25
0.0%
3.5%
Q3 25
0.0%
1.6%
Q2 25
0.0%
1.8%
Q1 25
0.1%
1.2%
Q4 24
0.0%
2.9%
Q3 24
0.0%
3.2%
Q2 24
0.1%
2.7%
Q1 24
0.1%
1.6%
Cash Conversion
IRWD
IRWD
LXFR
LXFR
Q4 25
Q3 25
1.19×
4.37×
Q2 25
-0.64×
0.46×
Q1 25
0.98×
Q4 24
6.74×
7.29×
Q3 24
2.71×
1.02×
Q2 24
Q1 24
1.37×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

IRWD
IRWD

Segment breakdown not available.

LXFR
LXFR

Gas Cylinders Segment$43.8M48%
Defense First Response And Healthcare$18.6M21%
Rest Of Europe$9.0M10%
DE$7.0M8%
Asia Pacific$5.8M6%
CA$4.0M4%
Other$2.5M3%

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