vs

Side-by-side financial comparison of IRONWOOD PHARMACEUTICALS INC (IRWD) and MFA FINANCIAL, INC. (MFA). Click either name above to swap in a different company.

MFA FINANCIAL, INC. is the larger business by last-quarter revenue ($55.5M vs $47.7M, roughly 1.2× IRONWOOD PHARMACEUTICALS INC). On growth, MFA FINANCIAL, INC. posted the faster year-over-year revenue change (9.2% vs -47.3%). Over the past eight quarters, MFA FINANCIAL, INC.'s revenue compounded faster (7.7% CAGR vs -20.2%).

Ironwood Pharmaceuticals, Inc. is a publicly traded pharmaceutical company. It was originally called Microbia, Inc.

MFA Financial, Inc. is a U.S.-headquartered real estate investment trust (REIT) specializing in investing in and managing residential and commercial mortgage-backed securities, mortgage loans, and other real estate-related financial assets. It caters primarily to institutional and individual investors across the U.S., focusing on delivering stable risk-adjusted returns via rigorous asset screening and risk management frameworks.

IRWD vs MFA — Head-to-Head

Bigger by revenue
MFA
MFA
1.2× larger
MFA
$55.5M
$47.7M
IRWD
Growing faster (revenue YoY)
MFA
MFA
+56.5% gap
MFA
9.2%
-47.3%
IRWD
Faster 2-yr revenue CAGR
MFA
MFA
Annualised
MFA
7.7%
-20.2%
IRWD

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
IRWD
IRWD
MFA
MFA
Revenue
$47.7M
$55.5M
Net Profit
$-2.3M
Gross Margin
Operating Margin
14.3%
97.9%
Net Margin
-4.8%
Revenue YoY
-47.3%
9.2%
Net Profit YoY
-200.9%
EPS (diluted)
$0.01
$0.43

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
IRWD
IRWD
MFA
MFA
Q4 25
$47.7M
$55.5M
Q3 25
$122.1M
$56.8M
Q2 25
$85.2M
$61.3M
Q1 25
$41.1M
$57.5M
Q4 24
$90.5M
$50.8M
Q3 24
$91.6M
$50.6M
Q2 24
$94.4M
$53.5M
Q1 24
$74.9M
$47.8M
Net Profit
IRWD
IRWD
MFA
MFA
Q4 25
$-2.3M
Q3 25
$40.1M
$48.1M
Q2 25
$23.6M
$33.2M
Q1 25
$-37.4M
$41.2M
Q4 24
$2.3M
Q3 24
$3.6M
$48.2M
Q2 24
$-860.0K
$41.9M
Q1 24
$-4.2M
$23.2M
Operating Margin
IRWD
IRWD
MFA
MFA
Q4 25
14.3%
97.9%
Q3 25
61.8%
84.5%
Q2 25
53.2%
54.5%
Q1 25
-70.7%
70.0%
Q4 24
34.8%
6.8%
Q3 24
28.0%
98.2%
Q2 24
26.5%
79.1%
Q1 24
14.7%
50.7%
Net Margin
IRWD
IRWD
MFA
MFA
Q4 25
-4.8%
Q3 25
32.8%
84.7%
Q2 25
27.7%
54.2%
Q1 25
-90.9%
71.6%
Q4 24
2.5%
Q3 24
4.0%
95.2%
Q2 24
-0.9%
78.4%
Q1 24
-5.6%
48.5%
EPS (diluted)
IRWD
IRWD
MFA
MFA
Q4 25
$0.01
$0.43
Q3 25
$0.23
$0.35
Q2 25
$0.14
$0.21
Q1 25
$-0.23
$0.31
Q4 24
$0.03
$-0.01
Q3 24
$0.02
$0.37
Q2 24
$-0.01
$0.32
Q1 24
$-0.03
$0.14

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
IRWD
IRWD
MFA
MFA
Cash + ST InvestmentsLiquidity on hand
$215.5M
$213.2M
Total DebtLower is stronger
Stockholders' EquityBook value
$-261.8M
$1.8B
Total Assets
$396.9M
$13.0B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
IRWD
IRWD
MFA
MFA
Q4 25
$215.5M
$213.2M
Q3 25
$140.4M
$305.2M
Q2 25
$92.9M
$275.7M
Q1 25
$108.5M
$253.7M
Q4 24
$88.6M
$338.9M
Q3 24
$88.2M
$305.6M
Q2 24
$105.5M
$289.4M
Q1 24
$121.5M
$306.3M
Total Debt
IRWD
IRWD
MFA
MFA
Q4 25
Q3 25
$199.5M
Q2 25
$199.3M
Q1 25
$199.2M
Q4 24
$199.0M
Q3 24
$198.8M
Q2 24
$198.6M
Q1 24
$398.3M
Stockholders' Equity
IRWD
IRWD
MFA
MFA
Q4 25
$-261.8M
$1.8B
Q3 25
$-264.2M
$1.8B
Q2 25
$-308.2M
$1.8B
Q1 25
$-334.1M
$1.8B
Q4 24
$-301.3M
$1.8B
Q3 24
$-311.3M
$1.9B
Q2 24
$-321.7M
$1.9B
Q1 24
$-330.5M
$1.9B
Total Assets
IRWD
IRWD
MFA
MFA
Q4 25
$396.9M
$13.0B
Q3 25
$396.1M
$12.1B
Q2 25
$342.9M
$11.7B
Q1 25
$327.2M
$11.5B
Q4 24
$350.9M
$11.4B
Q3 24
$389.5M
$11.2B
Q2 24
$395.6M
$11.1B
Q1 24
$438.8M
$10.9B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
IRWD
IRWD
MFA
MFA
Operating Cash FlowLast quarter
$74.6M
$76.2M
Free Cash FlowOCF − Capex
$74.6M
FCF MarginFCF / Revenue
156.3%
Capex IntensityCapex / Revenue
0.0%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$127.0M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
IRWD
IRWD
MFA
MFA
Q4 25
$74.6M
$76.2M
Q3 25
$47.6M
$14.7M
Q2 25
$-15.1M
$38.5M
Q1 25
$20.0M
$-14.6M
Q4 24
$15.2M
$200.1M
Q3 24
$9.9M
$-11.3M
Q2 24
$33.5M
$46.5M
Q1 24
$45.0M
$53.5M
Free Cash Flow
IRWD
IRWD
MFA
MFA
Q4 25
$74.6M
Q3 25
$47.6M
Q2 25
$-15.1M
Q1 25
$19.9M
Q4 24
Q3 24
$9.9M
Q2 24
$33.4M
Q1 24
$44.9M
FCF Margin
IRWD
IRWD
MFA
MFA
Q4 25
156.3%
Q3 25
39.0%
Q2 25
-17.7%
Q1 25
48.4%
Q4 24
Q3 24
10.8%
Q2 24
35.4%
Q1 24
60.0%
Capex Intensity
IRWD
IRWD
MFA
MFA
Q4 25
0.0%
Q3 25
0.0%
Q2 25
0.0%
Q1 25
0.1%
Q4 24
0.0%
Q3 24
0.0%
Q2 24
0.1%
Q1 24
0.1%
Cash Conversion
IRWD
IRWD
MFA
MFA
Q4 25
Q3 25
1.19×
0.31×
Q2 25
-0.64×
1.16×
Q1 25
-0.35×
Q4 24
6.74×
Q3 24
2.71×
-0.23×
Q2 24
1.11×
Q1 24
2.30×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Related Comparisons