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Side-by-side financial comparison of IRONWOOD PHARMACEUTICALS INC (IRWD) and OptimizeRx Corp (OPRX). Click either name above to swap in a different company.

IRONWOOD PHARMACEUTICALS INC is the larger business by last-quarter revenue ($47.7M vs $32.2M, roughly 1.5× OptimizeRx Corp). OptimizeRx Corp runs the higher net margin — 15.6% vs -4.8%, a 20.3% gap on every dollar of revenue. On growth, OptimizeRx Corp posted the faster year-over-year revenue change (-0.2% vs -47.3%). IRONWOOD PHARMACEUTICALS INC produced more free cash flow last quarter ($74.6M vs $7.1M). Over the past eight quarters, OptimizeRx Corp's revenue compounded faster (28.0% CAGR vs -20.2%).

Ironwood Pharmaceuticals, Inc. is a publicly traded pharmaceutical company. It was originally called Microbia, Inc.

OptimizeRx Corp is a U.S.-headquartered digital health technology company that delivers patient engagement, medication affordability and clinical communication solutions to life sciences enterprises, healthcare providers and pharmacy partners. Its core offerings include digital medication savings tools, patient support programs, and therapeutic area-specific resources to boost medication access and treatment adherence.

IRWD vs OPRX — Head-to-Head

Bigger by revenue
IRWD
IRWD
1.5× larger
IRWD
$47.7M
$32.2M
OPRX
Growing faster (revenue YoY)
OPRX
OPRX
+47.1% gap
OPRX
-0.2%
-47.3%
IRWD
Higher net margin
OPRX
OPRX
20.3% more per $
OPRX
15.6%
-4.8%
IRWD
More free cash flow
IRWD
IRWD
$67.5M more FCF
IRWD
$74.6M
$7.1M
OPRX
Faster 2-yr revenue CAGR
OPRX
OPRX
Annualised
OPRX
28.0%
-20.2%
IRWD

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
IRWD
IRWD
OPRX
OPRX
Revenue
$47.7M
$32.2M
Net Profit
$-2.3M
$5.0M
Gross Margin
74.8%
Operating Margin
14.3%
26.6%
Net Margin
-4.8%
15.6%
Revenue YoY
-47.3%
-0.2%
Net Profit YoY
-200.9%
6535.9%
EPS (diluted)
$0.01
$0.27

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
IRWD
IRWD
OPRX
OPRX
Q4 25
$47.7M
$32.2M
Q3 25
$122.1M
$26.1M
Q2 25
$85.2M
$29.2M
Q1 25
$41.1M
$21.9M
Q4 24
$90.5M
$32.3M
Q3 24
$91.6M
$21.3M
Q2 24
$94.4M
$18.8M
Q1 24
$74.9M
$19.7M
Net Profit
IRWD
IRWD
OPRX
OPRX
Q4 25
$-2.3M
$5.0M
Q3 25
$40.1M
$779.0K
Q2 25
$23.6M
$1.5M
Q1 25
$-37.4M
$-2.2M
Q4 24
$2.3M
$-78.0K
Q3 24
$3.6M
$-9.1M
Q2 24
$-860.0K
$-4.0M
Q1 24
$-4.2M
$-6.9M
Gross Margin
IRWD
IRWD
OPRX
OPRX
Q4 25
74.8%
Q3 25
67.2%
Q2 25
63.8%
Q1 25
60.9%
Q4 24
68.1%
Q3 24
63.1%
Q2 24
62.2%
Q1 24
62.0%
Operating Margin
IRWD
IRWD
OPRX
OPRX
Q4 25
14.3%
26.6%
Q3 25
61.8%
7.9%
Q2 25
53.2%
10.9%
Q1 25
-70.7%
-9.6%
Q4 24
34.8%
11.2%
Q3 24
28.0%
-40.2%
Q2 24
26.5%
-19.9%
Q1 24
14.7%
-25.5%
Net Margin
IRWD
IRWD
OPRX
OPRX
Q4 25
-4.8%
15.6%
Q3 25
32.8%
3.0%
Q2 25
27.7%
5.2%
Q1 25
-90.9%
-10.0%
Q4 24
2.5%
-0.2%
Q3 24
4.0%
-42.8%
Q2 24
-0.9%
-21.3%
Q1 24
-5.6%
-35.0%
EPS (diluted)
IRWD
IRWD
OPRX
OPRX
Q4 25
$0.01
$0.27
Q3 25
$0.23
$0.04
Q2 25
$0.14
$0.08
Q1 25
$-0.23
$-0.12
Q4 24
$0.03
$0.00
Q3 24
$0.02
$-0.50
Q2 24
$-0.01
$-0.22
Q1 24
$-0.03
$-0.38

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
IRWD
IRWD
OPRX
OPRX
Cash + ST InvestmentsLiquidity on hand
$215.5M
$23.4M
Total DebtLower is stronger
$26.3M
Stockholders' EquityBook value
$-261.8M
$128.3M
Total Assets
$396.9M
$176.9M
Debt / EquityLower = less leverage
0.20×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
IRWD
IRWD
OPRX
OPRX
Q4 25
$215.5M
$23.4M
Q3 25
$140.4M
$19.5M
Q2 25
$92.9M
$16.6M
Q1 25
$108.5M
$16.6M
Q4 24
$88.6M
$13.4M
Q3 24
$88.2M
$16.1M
Q2 24
$105.5M
Q1 24
$121.5M
Total Debt
IRWD
IRWD
OPRX
OPRX
Q4 25
$26.3M
Q3 25
$199.5M
$28.8M
Q2 25
$199.3M
$29.3M
Q1 25
$199.2M
$33.8M
Q4 24
$199.0M
$34.3M
Q3 24
$198.8M
$36.8M
Q2 24
$198.6M
$37.3M
Q1 24
$398.3M
$37.8M
Stockholders' Equity
IRWD
IRWD
OPRX
OPRX
Q4 25
$-261.8M
$128.3M
Q3 25
$-264.2M
$122.3M
Q2 25
$-308.2M
$119.3M
Q1 25
$-334.1M
$116.3M
Q4 24
$-301.3M
$117.0M
Q3 24
$-311.3M
$114.5M
Q2 24
$-321.7M
$121.0M
Q1 24
$-330.5M
$122.5M
Total Assets
IRWD
IRWD
OPRX
OPRX
Q4 25
$396.9M
$176.9M
Q3 25
$396.1M
$170.3M
Q2 25
$342.9M
$169.3M
Q1 25
$327.2M
$167.8M
Q4 24
$350.9M
$171.2M
Q3 24
$389.5M
$165.2M
Q2 24
$395.6M
$172.9M
Q1 24
$438.8M
$176.4M
Debt / Equity
IRWD
IRWD
OPRX
OPRX
Q4 25
0.20×
Q3 25
0.24×
Q2 25
0.25×
Q1 25
0.29×
Q4 24
0.29×
Q3 24
0.32×
Q2 24
0.31×
Q1 24
0.31×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
IRWD
IRWD
OPRX
OPRX
Operating Cash FlowLast quarter
$74.6M
$7.1M
Free Cash FlowOCF − Capex
$74.6M
$7.1M
FCF MarginFCF / Revenue
156.3%
22.0%
Capex IntensityCapex / Revenue
0.0%
0.0%
Cash ConversionOCF / Net Profit
1.41×
TTM Free Cash FlowTrailing 4 quarters
$127.0M
$18.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
IRWD
IRWD
OPRX
OPRX
Q4 25
$74.6M
$7.1M
Q3 25
$47.6M
$3.2M
Q2 25
$-15.1M
$4.6M
Q1 25
$20.0M
$3.9M
Q4 24
$15.2M
$198.0K
Q3 24
$9.9M
$1.8M
Q2 24
$33.5M
$782.0K
Q1 24
$45.0M
$2.1M
Free Cash Flow
IRWD
IRWD
OPRX
OPRX
Q4 25
$74.6M
$7.1M
Q3 25
$47.6M
$3.2M
Q2 25
$-15.1M
$4.6M
Q1 25
$19.9M
$3.8M
Q4 24
$181.0K
Q3 24
$9.9M
$1.8M
Q2 24
$33.4M
$737.0K
Q1 24
$44.9M
$2.1M
FCF Margin
IRWD
IRWD
OPRX
OPRX
Q4 25
156.3%
22.0%
Q3 25
39.0%
12.2%
Q2 25
-17.7%
15.6%
Q1 25
48.4%
17.5%
Q4 24
0.6%
Q3 24
10.8%
8.3%
Q2 24
35.4%
3.9%
Q1 24
60.0%
10.6%
Capex Intensity
IRWD
IRWD
OPRX
OPRX
Q4 25
0.0%
0.0%
Q3 25
0.0%
0.0%
Q2 25
0.0%
0.0%
Q1 25
0.1%
0.1%
Q4 24
0.0%
0.1%
Q3 24
0.0%
0.1%
Q2 24
0.1%
0.2%
Q1 24
0.1%
0.2%
Cash Conversion
IRWD
IRWD
OPRX
OPRX
Q4 25
1.41×
Q3 25
1.19×
4.11×
Q2 25
-0.64×
2.98×
Q1 25
Q4 24
6.74×
Q3 24
2.71×
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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