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Side-by-side financial comparison of IRONWOOD PHARMACEUTICALS INC (IRWD) and Spok Holdings, Inc (SPOK). Click either name above to swap in a different company.

IRONWOOD PHARMACEUTICALS INC is the larger business by last-quarter revenue ($47.7M vs $33.9M, roughly 1.4× Spok Holdings, Inc). Spok Holdings, Inc runs the higher net margin — 8.7% vs -4.8%, a 13.4% gap on every dollar of revenue. On growth, Spok Holdings, Inc posted the faster year-over-year revenue change (-0.1% vs -47.3%). IRONWOOD PHARMACEUTICALS INC produced more free cash flow last quarter ($74.6M vs $10.1M). Over the past eight quarters, Spok Holdings, Inc's revenue compounded faster (-1.5% CAGR vs -20.2%).

Ironwood Pharmaceuticals, Inc. is a publicly traded pharmaceutical company. It was originally called Microbia, Inc.

Spok Holdings, Inc. is a global provider of critical communication solutions primarily serving the healthcare industry. It offers unified clinical communication platforms, secure messaging tools, alerting systems, and on-call scheduling software that help care teams coordinate efficiently, cut response times, and boost patient safety across medical facilities.

IRWD vs SPOK — Head-to-Head

Bigger by revenue
IRWD
IRWD
1.4× larger
IRWD
$47.7M
$33.9M
SPOK
Growing faster (revenue YoY)
SPOK
SPOK
+47.2% gap
SPOK
-0.1%
-47.3%
IRWD
Higher net margin
SPOK
SPOK
13.4% more per $
SPOK
8.7%
-4.8%
IRWD
More free cash flow
IRWD
IRWD
$64.5M more FCF
IRWD
$74.6M
$10.1M
SPOK
Faster 2-yr revenue CAGR
SPOK
SPOK
Annualised
SPOK
-1.5%
-20.2%
IRWD

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
IRWD
IRWD
SPOK
SPOK
Revenue
$47.7M
$33.9M
Net Profit
$-2.3M
$2.9M
Gross Margin
76.7%
Operating Margin
14.3%
11.6%
Net Margin
-4.8%
8.7%
Revenue YoY
-47.3%
-0.1%
Net Profit YoY
-200.9%
-19.6%
EPS (diluted)
$0.01
$0.13

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
IRWD
IRWD
SPOK
SPOK
Q4 25
$47.7M
$33.9M
Q3 25
$122.1M
$33.9M
Q2 25
$85.2M
$35.7M
Q1 25
$41.1M
$36.3M
Q4 24
$90.5M
$33.9M
Q3 24
$91.6M
$34.9M
Q2 24
$94.4M
$34.0M
Q1 24
$74.9M
$34.9M
Net Profit
IRWD
IRWD
SPOK
SPOK
Q4 25
$-2.3M
$2.9M
Q3 25
$40.1M
$3.2M
Q2 25
$23.6M
$4.6M
Q1 25
$-37.4M
$5.2M
Q4 24
$2.3M
$3.6M
Q3 24
$3.6M
$3.7M
Q2 24
$-860.0K
$3.4M
Q1 24
$-4.2M
$4.2M
Gross Margin
IRWD
IRWD
SPOK
SPOK
Q4 25
76.7%
Q3 25
78.3%
Q2 25
79.5%
Q1 25
80.1%
Q4 24
78.5%
Q3 24
79.5%
Q2 24
78.9%
Q1 24
79.5%
Operating Margin
IRWD
IRWD
SPOK
SPOK
Q4 25
14.3%
11.6%
Q3 25
61.8%
12.9%
Q2 25
53.2%
15.1%
Q1 25
-70.7%
16.6%
Q4 24
34.8%
13.7%
Q3 24
28.0%
14.2%
Q2 24
26.5%
13.2%
Q1 24
14.7%
14.0%
Net Margin
IRWD
IRWD
SPOK
SPOK
Q4 25
-4.8%
8.7%
Q3 25
32.8%
9.5%
Q2 25
27.7%
12.8%
Q1 25
-90.9%
14.3%
Q4 24
2.5%
10.8%
Q3 24
4.0%
10.5%
Q2 24
-0.9%
10.1%
Q1 24
-5.6%
12.1%
EPS (diluted)
IRWD
IRWD
SPOK
SPOK
Q4 25
$0.01
$0.13
Q3 25
$0.23
$0.15
Q2 25
$0.14
$0.22
Q1 25
$-0.23
$0.25
Q4 24
$0.03
$0.17
Q3 24
$0.02
$0.18
Q2 24
$-0.01
$0.17
Q1 24
$-0.03
$0.21

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
IRWD
IRWD
SPOK
SPOK
Cash + ST InvestmentsLiquidity on hand
$215.5M
$25.3M
Total DebtLower is stronger
Stockholders' EquityBook value
$-261.8M
$146.4M
Total Assets
$396.9M
$206.1M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
IRWD
IRWD
SPOK
SPOK
Q4 25
$215.5M
$25.3M
Q3 25
$140.4M
$21.4M
Q2 25
$92.9M
$20.2M
Q1 25
$108.5M
$19.9M
Q4 24
$88.6M
$29.1M
Q3 24
$88.2M
$27.8M
Q2 24
$105.5M
$23.9M
Q1 24
$121.5M
$23.3M
Total Debt
IRWD
IRWD
SPOK
SPOK
Q4 25
Q3 25
$199.5M
Q2 25
$199.3M
Q1 25
$199.2M
Q4 24
$199.0M
Q3 24
$198.8M
Q2 24
$198.6M
Q1 24
$398.3M
Stockholders' Equity
IRWD
IRWD
SPOK
SPOK
Q4 25
$-261.8M
$146.4M
Q3 25
$-264.2M
$148.7M
Q2 25
$-308.2M
$150.9M
Q1 25
$-334.1M
$151.7M
Q4 24
$-301.3M
$154.7M
Q3 24
$-311.3M
$156.3M
Q2 24
$-321.7M
$158.2M
Q1 24
$-330.5M
$160.2M
Total Assets
IRWD
IRWD
SPOK
SPOK
Q4 25
$396.9M
$206.1M
Q3 25
$396.1M
$209.7M
Q2 25
$342.9M
$208.7M
Q1 25
$327.2M
$204.5M
Q4 24
$350.9M
$217.1M
Q3 24
$389.5M
$216.8M
Q2 24
$395.6M
$216.4M
Q1 24
$438.8M
$215.0M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
IRWD
IRWD
SPOK
SPOK
Operating Cash FlowLast quarter
$74.6M
$11.5M
Free Cash FlowOCF − Capex
$74.6M
$10.1M
FCF MarginFCF / Revenue
156.3%
29.9%
Capex IntensityCapex / Revenue
0.0%
4.1%
Cash ConversionOCF / Net Profit
3.93×
TTM Free Cash FlowTrailing 4 quarters
$127.0M
$25.2M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
IRWD
IRWD
SPOK
SPOK
Q4 25
$74.6M
$11.5M
Q3 25
$47.6M
$8.1M
Q2 25
$-15.1M
$7.0M
Q1 25
$20.0M
$2.3M
Q4 24
$15.2M
$8.4M
Q3 24
$9.9M
$11.1M
Q2 24
$33.5M
$7.4M
Q1 24
$45.0M
$2.0M
Free Cash Flow
IRWD
IRWD
SPOK
SPOK
Q4 25
$74.6M
$10.1M
Q3 25
$47.6M
$7.6M
Q2 25
$-15.1M
$6.0M
Q1 25
$19.9M
$1.5M
Q4 24
$7.5M
Q3 24
$9.9M
$10.3M
Q2 24
$33.4M
$6.8M
Q1 24
$44.9M
$1.1M
FCF Margin
IRWD
IRWD
SPOK
SPOK
Q4 25
156.3%
29.9%
Q3 25
39.0%
22.4%
Q2 25
-17.7%
16.8%
Q1 25
48.4%
4.2%
Q4 24
22.3%
Q3 24
10.8%
29.4%
Q2 24
35.4%
20.0%
Q1 24
60.0%
3.2%
Capex Intensity
IRWD
IRWD
SPOK
SPOK
Q4 25
0.0%
4.1%
Q3 25
0.0%
1.6%
Q2 25
0.0%
2.9%
Q1 25
0.1%
2.1%
Q4 24
0.0%
2.5%
Q3 24
0.0%
2.4%
Q2 24
0.1%
1.9%
Q1 24
0.1%
2.5%
Cash Conversion
IRWD
IRWD
SPOK
SPOK
Q4 25
3.93×
Q3 25
1.19×
2.54×
Q2 25
-0.64×
1.55×
Q1 25
0.43×
Q4 24
6.74×
2.31×
Q3 24
2.71×
3.03×
Q2 24
2.17×
Q1 24
0.47×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

IRWD
IRWD

Segment breakdown not available.

SPOK
SPOK

Paging$16.8M50%
Software Operations$16.0M47%
License$1.2M4%

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