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Side-by-side financial comparison of iSpecimen Inc. (ISPC) and PLUS THERAPEUTICS, INC. (PSTV). Click either name above to swap in a different company.

PLUS THERAPEUTICS, INC. is the larger business by last-quarter revenue ($1.4M vs $713.1K, roughly 1.9× iSpecimen Inc.). iSpecimen Inc. runs the higher net margin — -146.9% vs -417.9%, a 271.1% gap on every dollar of revenue. On growth, PLUS THERAPEUTICS, INC. posted the faster year-over-year revenue change (-3.2% vs -75.1%). Over the past eight quarters, PLUS THERAPEUTICS, INC.'s revenue compounded faster (-9.7% CAGR vs -49.3%).

Specimen Products is a Chicago-based manufacturer of custom guitars, tube amplifiers, and audio horn speakers led by luthier Ian Schneller. Specimen Products also offers courses in guitar and tube amplifier design, construction, and repair through their Chicago School of Guitar Making. The Specimen workshop offers repair services to the general public, making use of their collection of parts from rare and vintage manufacturers.

Plus Therapeutics, Inc. is a clinical-stage pharmaceutical company headquartered in Houston, Texas, that develops targeted radiotherapeutics and diagnostic services for brain and central nervous system (CNS) cancers. The company’s lead therapeutic candidate, marketed as REYOBIQ™, is an investigational liposomal radiopharmaceutical under clinical evaluation for recurrent glioblastoma, leptomeningeal metastases, and certain pediatric brain cancers. Plus Therapeutics also commercialized a molecu...

ISPC vs PSTV — Head-to-Head

Bigger by revenue
PSTV
PSTV
1.9× larger
PSTV
$1.4M
$713.1K
ISPC
Growing faster (revenue YoY)
PSTV
PSTV
+71.9% gap
PSTV
-3.2%
-75.1%
ISPC
Higher net margin
ISPC
ISPC
271.1% more per $
ISPC
-146.9%
-417.9%
PSTV
Faster 2-yr revenue CAGR
PSTV
PSTV
Annualised
PSTV
-9.7%
-49.3%
ISPC

Income Statement — Q2 FY2025 vs Q4 FY2025

Metric
ISPC
ISPC
PSTV
PSTV
Revenue
$713.1K
$1.4M
Net Profit
$-1.0M
$-5.7M
Gross Margin
44.4%
Operating Margin
-255.4%
-420.0%
Net Margin
-146.9%
-417.9%
Revenue YoY
-75.1%
-3.2%
Net Profit YoY
50.3%
-46.4%
EPS (diluted)
$-0.42
$0.95

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ISPC
ISPC
PSTV
PSTV
Q4 25
$1.4M
Q3 25
$1.4M
Q2 25
$713.1K
$1.4M
Q1 25
$1.1M
$1.1M
Q4 24
$1.5M
$1.4M
Q3 24
$2.7M
$1.5M
Q2 24
$2.9M
$1.3M
Q1 24
$2.3M
$1.7M
Net Profit
ISPC
ISPC
PSTV
PSTV
Q4 25
$-5.7M
Q3 25
$-4.4M
Q2 25
$-1.0M
$5.2M
Q1 25
$-1.7M
$-17.4M
Q4 24
$-6.0M
$-3.9M
Q3 24
$-1.4M
$-2.9M
Q2 24
$-2.1M
$-2.9M
Q1 24
$-2.9M
$-3.3M
Gross Margin
ISPC
ISPC
PSTV
PSTV
Q4 25
Q3 25
Q2 25
44.4%
Q1 25
42.4%
Q4 24
13.5%
Q3 24
43.4%
Q2 24
51.9%
Q1 24
58.4%
Operating Margin
ISPC
ISPC
PSTV
PSTV
Q4 25
-420.0%
Q3 25
-320.8%
Q2 25
-255.4%
-110.6%
Q1 25
-154.9%
-333.9%
Q4 24
-395.8%
-276.2%
Q3 24
-64.1%
-260.9%
Q2 24
-76.2%
-289.1%
Q1 24
-131.0%
-196.7%
Net Margin
ISPC
ISPC
PSTV
PSTV
Q4 25
-417.9%
Q3 25
-316.6%
Q2 25
-146.9%
370.6%
Q1 25
-156.8%
-1643.2%
Q4 24
-409.8%
-276.4%
Q3 24
-54.1%
-197.4%
Q2 24
-73.6%
-229.9%
Q1 24
-126.7%
-194.5%
EPS (diluted)
ISPC
ISPC
PSTV
PSTV
Q4 25
$0.95
Q3 25
$-0.04
Q2 25
$-0.42
$-0.01
Q1 25
$-0.71
$-1.19
Q4 24
$-5.40
$-0.51
Q3 24
$-2.10
$-0.37
Q2 24
$-3.72
$-0.71
Q1 24
$-6.36
$-0.75

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ISPC
ISPC
PSTV
PSTV
Cash + ST InvestmentsLiquidity on hand
$8.6M
Total DebtLower is stronger
Stockholders' EquityBook value
$622.0K
$4.0M
Total Assets
$6.0M
$16.3M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ISPC
ISPC
PSTV
PSTV
Q4 25
$8.6M
Q3 25
$16.6M
Q2 25
$6.9M
Q1 25
$9.9M
Q4 24
$1.9M
$3.6M
Q3 24
$1.8M
$4.8M
Q2 24
$2.2M
$8.4M
Q1 24
$2.1M
$3.2M
Stockholders' Equity
ISPC
ISPC
PSTV
PSTV
Q4 25
$4.0M
Q3 25
$5.1M
Q2 25
$622.0K
$3.0M
Q1 25
$1.7M
$-23.6M
Q4 24
$3.3M
$-8.9M
Q3 24
$4.7M
$-5.2M
Q2 24
$6.1M
$-7.6M
Q1 24
$6.8M
$-4.8M
Total Assets
ISPC
ISPC
PSTV
PSTV
Q4 25
$16.3M
Q3 25
$18.7M
Q2 25
$6.0M
$10.3M
Q1 25
$6.8M
$12.1M
Q4 24
$9.4M
$6.6M
Q3 24
$11.3M
$7.0M
Q2 24
$11.9M
$11.2M
Q1 24
$12.5M
$5.6M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ISPC
ISPC
PSTV
PSTV
Operating Cash FlowLast quarter
$-192.2K
$-6.3M
Free Cash FlowOCF − Capex
$-6.3M
FCF MarginFCF / Revenue
-459.9%
Capex IntensityCapex / Revenue
2.2%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-20.8M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ISPC
ISPC
PSTV
PSTV
Q4 25
$-6.3M
Q3 25
$-2.5M
Q2 25
$-192.2K
$-5.8M
Q1 25
$-1.1M
$-6.2M
Q4 24
$-3.6M
$-1.2M
Q3 24
$-1.1M
$-3.7M
Q2 24
$-1.5M
$-1.1M
Q1 24
$-2.1M
$-4.5M
Free Cash Flow
ISPC
ISPC
PSTV
PSTV
Q4 25
$-6.3M
Q3 25
$-2.6M
Q2 25
$-5.8M
Q1 25
$-6.2M
Q4 24
$-3.6M
$-1.2M
Q3 24
$-1.1M
$-3.7M
Q2 24
$-1.2M
Q1 24
$-2.1M
$-4.6M
FCF Margin
ISPC
ISPC
PSTV
PSTV
Q4 25
-459.9%
Q3 25
-184.3%
Q2 25
-417.6%
Q1 25
-583.1%
Q4 24
-242.7%
-86.5%
Q3 24
-41.1%
-253.7%
Q2 24
-96.2%
Q1 24
-90.9%
-271.5%
Capex Intensity
ISPC
ISPC
PSTV
PSTV
Q4 25
2.2%
Q3 25
1.9%
Q2 25
0.5%
Q1 25
0.3%
Q4 24
0.5%
0.8%
Q3 24
0.5%
1.0%
Q2 24
0.0%
6.3%
Q1 24
0.4%
2.4%
Cash Conversion
ISPC
ISPC
PSTV
PSTV
Q4 25
Q3 25
Q2 25
-1.13×
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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