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Side-by-side financial comparison of James River Group Holdings, Inc. (JRVR) and PTC THERAPEUTICS, INC. (PTCT). Click either name above to swap in a different company.

James River Group Holdings, Inc. is the larger business by last-quarter revenue ($167.7M vs $164.7M, roughly 1.0× PTC THERAPEUTICS, INC.). James River Group Holdings, Inc. runs the higher net margin — 19.1% vs -82.0%, a 101.1% gap on every dollar of revenue. On growth, James River Group Holdings, Inc. posted the faster year-over-year revenue change (32.4% vs -22.7%). James River Group Holdings, Inc. produced more free cash flow last quarter ($-23.6M vs $-36.6M). Over the past eight quarters, James River Group Holdings, Inc.'s revenue compounded faster (-8.7% CAGR vs -11.5%).

James River Corporation was an American pulp and paper company based in Richmond, Virginia, once the largest paper manufacturer in the world.

PTC Therapeutics, Inc. is a US pharmaceutical company focused on the development of orally administered small molecule drugs and gene therapy which regulate gene expression by targeting post-transcriptional control (PTC) mechanisms in orphan diseases.

JRVR vs PTCT — Head-to-Head

Bigger by revenue
JRVR
JRVR
1.0× larger
JRVR
$167.7M
$164.7M
PTCT
Growing faster (revenue YoY)
JRVR
JRVR
+55.1% gap
JRVR
32.4%
-22.7%
PTCT
Higher net margin
JRVR
JRVR
101.1% more per $
JRVR
19.1%
-82.0%
PTCT
More free cash flow
JRVR
JRVR
$13.1M more FCF
JRVR
$-23.6M
$-36.6M
PTCT
Faster 2-yr revenue CAGR
JRVR
JRVR
Annualised
JRVR
-8.7%
-11.5%
PTCT

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
JRVR
JRVR
PTCT
PTCT
Revenue
$167.7M
$164.7M
Net Profit
$32.1M
$-135.0M
Gross Margin
Operating Margin
14.6%
-43.3%
Net Margin
19.1%
-82.0%
Revenue YoY
32.4%
-22.7%
Net Profit YoY
149.5%
-104.8%
EPS (diluted)
$0.59
$-1.63

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
JRVR
JRVR
PTCT
PTCT
Q4 25
$167.7M
$164.7M
Q3 25
$172.7M
$211.0M
Q2 25
$174.8M
$178.9M
Q1 25
$172.3M
$1.2B
Q4 24
$126.7M
$213.2M
Q3 24
$191.5M
$196.8M
Q2 24
$188.3M
$186.7M
Q1 24
$201.1M
$210.1M
Net Profit
JRVR
JRVR
PTCT
PTCT
Q4 25
$32.1M
$-135.0M
Q3 25
$1.0M
$15.9M
Q2 25
$4.8M
$-64.8M
Q1 25
$9.6M
$866.6M
Q4 24
$-64.8M
$-65.9M
Q3 24
$-39.4M
$-106.7M
Q2 24
$7.6M
$-99.2M
Q1 24
$15.4M
$-91.6M
Operating Margin
JRVR
JRVR
PTCT
PTCT
Q4 25
14.6%
-43.3%
Q3 25
1.5%
1.4%
Q2 25
4.2%
-19.5%
Q1 25
9.3%
82.5%
Q4 24
-57.0%
-76.2%
Q3 24
-27.1%
-27.7%
Q2 24
10.7%
-21.5%
Q1 24
16.4%
-21.6%
Net Margin
JRVR
JRVR
PTCT
PTCT
Q4 25
19.1%
-82.0%
Q3 25
0.6%
7.5%
Q2 25
2.7%
-36.3%
Q1 25
5.6%
73.7%
Q4 24
-51.1%
-30.9%
Q3 24
-20.6%
-54.2%
Q2 24
4.0%
-53.1%
Q1 24
7.7%
-43.6%
EPS (diluted)
JRVR
JRVR
PTCT
PTCT
Q4 25
$0.59
$-1.63
Q3 25
$-0.02
$0.20
Q2 25
$0.06
$-0.83
Q1 25
$0.16
$10.04
Q4 24
$-2.44
$-0.85
Q3 24
$-1.10
$-1.39
Q2 24
$0.13
$-1.29
Q1 24
$0.35
$-1.20

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
JRVR
JRVR
PTCT
PTCT
Cash + ST InvestmentsLiquidity on hand
$260.9M
$1.9B
Total DebtLower is stronger
Stockholders' EquityBook value
$538.2M
$-205.3M
Total Assets
$4.9B
$2.9B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
JRVR
JRVR
PTCT
PTCT
Q4 25
$260.9M
$1.9B
Q3 25
$238.8M
$1.7B
Q2 25
$220.0M
$2.0B
Q1 25
$279.4M
$2.0B
Q4 24
$362.3M
$1.1B
Q3 24
$359.8M
$1.0B
Q2 24
$672.5M
$1.1B
Q1 24
$305.5M
$884.8M
Stockholders' Equity
JRVR
JRVR
PTCT
PTCT
Q4 25
$538.2M
$-205.3M
Q3 25
$503.6M
$-155.8M
Q2 25
$492.6M
$-206.5M
Q1 25
$484.5M
$-185.8M
Q4 24
$460.9M
$-1.1B
Q3 24
$530.3M
$-1.1B
Q2 24
$541.8M
$-980.2M
Q1 24
$539.5M
$-893.9M
Total Assets
JRVR
JRVR
PTCT
PTCT
Q4 25
$4.9B
$2.9B
Q3 25
$5.0B
$2.6B
Q2 25
$5.0B
$2.6B
Q1 25
$4.9B
$2.7B
Q4 24
$5.0B
$1.7B
Q3 24
$5.0B
$1.8B
Q2 24
$4.7B
$1.9B
Q1 24
$5.3B
$1.8B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
JRVR
JRVR
PTCT
PTCT
Operating Cash FlowLast quarter
$-18.8M
$-34.3M
Free Cash FlowOCF − Capex
$-23.6M
$-36.6M
FCF MarginFCF / Revenue
-14.1%
-22.3%
Capex IntensityCapex / Revenue
2.9%
1.4%
Cash ConversionOCF / Net Profit
-0.59×
TTM Free Cash FlowTrailing 4 quarters
$-17.9M
$702.3M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
JRVR
JRVR
PTCT
PTCT
Q4 25
$-18.8M
$-34.3M
Q3 25
$34.3M
$-66.3M
Q2 25
$25.2M
$-58.3M
Q1 25
$-51.5M
$870.1M
Q4 24
$-247.1M
$-30.0M
Q3 24
$-269.9M
$-77.0M
Q2 24
$-8.7M
$-71.5M
Q1 24
$24.1M
$70.8M
Free Cash Flow
JRVR
JRVR
PTCT
PTCT
Q4 25
$-23.6M
$-36.6M
Q3 25
$33.7M
$-69.7M
Q2 25
$24.7M
$-59.6M
Q1 25
$-52.7M
$868.4M
Q4 24
$-252.0M
$-33.8M
Q3 24
$-270.8M
$-77.5M
Q2 24
$-9.3M
$-78.8M
Q1 24
$23.3M
$61.2M
FCF Margin
JRVR
JRVR
PTCT
PTCT
Q4 25
-14.1%
-22.3%
Q3 25
19.5%
-33.1%
Q2 25
14.1%
-33.3%
Q1 25
-30.6%
73.8%
Q4 24
-198.9%
-15.8%
Q3 24
-141.4%
-39.4%
Q2 24
-4.9%
-42.2%
Q1 24
11.6%
29.1%
Capex Intensity
JRVR
JRVR
PTCT
PTCT
Q4 25
2.9%
1.4%
Q3 25
0.4%
1.6%
Q2 25
0.3%
0.7%
Q1 25
0.7%
0.1%
Q4 24
3.9%
1.8%
Q3 24
0.4%
0.3%
Q2 24
0.3%
4.0%
Q1 24
0.4%
4.6%
Cash Conversion
JRVR
JRVR
PTCT
PTCT
Q4 25
-0.59×
Q3 25
33.61×
-4.17×
Q2 25
5.29×
Q1 25
-5.38×
1.00×
Q4 24
Q3 24
Q2 24
-1.14×
Q1 24
1.56×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

JRVR
JRVR

Excess And Surplus Lines$156.7M93%
Specialty Admitted Insurance$10.9M7%

PTCT
PTCT

Segment breakdown not available.

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