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Side-by-side financial comparison of KalVista Pharmaceuticals, Inc. (KALV) and Spire Global, Inc. (SPIR). Click either name above to swap in a different company.

Spire Global, Inc. is the larger business by last-quarter revenue ($15.8M vs $13.7M, roughly 1.2× KalVista Pharmaceuticals, Inc.). Spire Global, Inc. runs the higher net margin — -176.6% vs -361.4%, a 184.8% gap on every dollar of revenue.

KalVista Pharmaceuticals is a clinical-stage biopharmaceutical company focused on the research, development and commercialization of novel oral serine protease inhibitor therapies. Its core pipeline addresses unmet medical needs for rare and inflammatory diseases including hereditary angioedema and diabetic macular edema, with primary target markets in North America and Europe.

Spire Global, Inc. is a space-to-cloud data and analytics company that specializes in the tracking of global data sets powered by a large constellation of nanosatellites, such as the tracking of maritime, aviation and weather patterns.

KALV vs SPIR — Head-to-Head

Bigger by revenue
SPIR
SPIR
1.2× larger
SPIR
$15.8M
$13.7M
KALV
Higher net margin
SPIR
SPIR
184.8% more per $
SPIR
-176.6%
-361.4%
KALV

Income Statement — Q2 FY2026 vs Q4 FY2025

Metric
KALV
KALV
SPIR
SPIR
Revenue
$13.7M
$15.8M
Net Profit
$-49.5M
$-28.0M
Gross Margin
91.0%
40.2%
Operating Margin
-336.3%
-164.1%
Net Margin
-361.4%
-176.6%
Revenue YoY
-26.9%
Net Profit YoY
-17.1%
42.7%
EPS (diluted)
$-0.92
$-0.85

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
KALV
KALV
SPIR
SPIR
Q4 25
$15.8M
Q3 25
$13.7M
$12.7M
Q2 25
$19.2M
Q1 25
$23.9M
Q4 24
$21.7M
Q3 24
$0
$28.6M
Q2 24
$25.4M
Q1 24
$34.8M
Net Profit
KALV
KALV
SPIR
SPIR
Q4 25
$-28.0M
Q3 25
$-49.5M
$-19.7M
Q2 25
$119.6M
Q1 25
$-20.7M
Q4 24
$-48.8M
Q3 24
$-40.4M
$-12.5M
Q2 24
$-16.6M
Q1 24
$-25.5M
Gross Margin
KALV
KALV
SPIR
SPIR
Q4 25
40.2%
Q3 25
91.0%
36.6%
Q2 25
48.9%
Q1 25
36.8%
Q4 24
32.4%
Q3 24
44.5%
Q2 24
43.0%
Q1 24
26.5%
Operating Margin
KALV
KALV
SPIR
SPIR
Q4 25
-164.1%
Q3 25
-336.3%
-166.1%
Q2 25
-122.7%
Q1 25
-106.5%
Q4 24
-144.1%
Q3 24
-48.0%
Q2 24
-48.6%
Q1 24
-34.4%
Net Margin
KALV
KALV
SPIR
SPIR
Q4 25
-176.6%
Q3 25
-361.4%
-155.3%
Q2 25
623.4%
Q1 25
-86.5%
Q4 24
-225.2%
Q3 24
-43.7%
Q2 24
-65.2%
Q1 24
-73.3%
EPS (diluted)
KALV
KALV
SPIR
SPIR
Q4 25
$-0.85
Q3 25
$-0.92
$-0.61
Q2 25
$3.72
Q1 25
$-0.77
Q4 24
$-1.93
Q3 24
$-0.87
$-0.50
Q2 24
$-0.68
Q1 24
$-1.17

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
KALV
KALV
SPIR
SPIR
Cash + ST InvestmentsLiquidity on hand
$243.5M
$81.8M
Total DebtLower is stronger
Stockholders' EquityBook value
$17.0M
$112.9M
Total Assets
$339.9M
$211.0M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
KALV
KALV
SPIR
SPIR
Q4 25
$81.8M
Q3 25
$243.5M
$96.8M
Q2 25
$117.6M
Q1 25
$35.9M
Q4 24
$19.2M
Q3 24
$31.8M
$36.6M
Q2 24
$45.8M
Q1 24
$63.7M
Total Debt
KALV
KALV
SPIR
SPIR
Q4 25
Q3 25
Q2 25
Q1 25
$103.7M
Q4 24
$103.1M
Q3 24
$4.9M
Q2 24
$4.9M
Q1 24
$123.1M
Stockholders' Equity
KALV
KALV
SPIR
SPIR
Q4 25
$112.9M
Q3 25
$17.0M
$133.1M
Q2 25
$149.2M
Q1 25
$3.7M
Q4 24
$-11.7M
Q3 24
$172.8M
$30.8M
Q2 24
$40.3M
Q1 24
$52.5M
Total Assets
KALV
KALV
SPIR
SPIR
Q4 25
$211.0M
Q3 25
$339.9M
$224.3M
Q2 25
$239.5M
Q1 25
$208.8M
Q4 24
$193.6M
Q3 24
$200.2M
$224.2M
Q2 24
$230.8M
Q1 24
$252.3M
Debt / Equity
KALV
KALV
SPIR
SPIR
Q4 25
Q3 25
Q2 25
Q1 25
27.92×
Q4 24
Q3 24
0.16×
Q2 24
0.12×
Q1 24
2.35×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
KALV
KALV
SPIR
SPIR
Operating Cash FlowLast quarter
$-4.3M
Free Cash FlowOCF − Capex
$-16.2M
FCF MarginFCF / Revenue
-102.1%
Capex IntensityCapex / Revenue
75.1%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-92.6M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
KALV
KALV
SPIR
SPIR
Q4 25
$-4.3M
Q3 25
$-12.0M
Q2 25
$-35.1M
Q1 25
$-8.4M
Q4 24
$-19.2M
Q3 24
$-40.2M
$14.0M
Q2 24
$-4.4M
Q1 24
$-8.8M
Free Cash Flow
KALV
KALV
SPIR
SPIR
Q4 25
$-16.2M
Q3 25
$-20.4M
Q2 25
$-38.7M
Q1 25
$-17.3M
Q4 24
$-24.3M
Q3 24
$-40.2M
$5.1M
Q2 24
$-9.9M
Q1 24
$-15.9M
FCF Margin
KALV
KALV
SPIR
SPIR
Q4 25
-102.1%
Q3 25
-161.3%
Q2 25
-201.7%
Q1 25
-72.6%
Q4 24
-112.2%
Q3 24
17.8%
Q2 24
-39.0%
Q1 24
-45.7%
Capex Intensity
KALV
KALV
SPIR
SPIR
Q4 25
75.1%
Q3 25
66.2%
Q2 25
18.8%
Q1 25
37.3%
Q4 24
23.5%
Q3 24
31.2%
Q2 24
21.8%
Q1 24
20.3%
Cash Conversion
KALV
KALV
SPIR
SPIR
Q4 25
Q3 25
Q2 25
-0.29×
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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