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Side-by-side financial comparison of Lumentum Holdings Inc. (LITE) and NEUROCRINE BIOSCIENCES INC (NBIX). Click either name above to swap in a different company.

NEUROCRINE BIOSCIENCES INC is the larger business by last-quarter revenue ($805.5M vs $665.5M, roughly 1.2× Lumentum Holdings Inc.). NEUROCRINE BIOSCIENCES INC runs the higher net margin — 19.1% vs 11.8%, a 7.3% gap on every dollar of revenue. On growth, Lumentum Holdings Inc. posted the faster year-over-year revenue change (65.5% vs 28.3%). NEUROCRINE BIOSCIENCES INC produced more free cash flow last quarter ($386.0M vs $43.1M). Over the past eight quarters, Lumentum Holdings Inc.'s revenue compounded faster (34.8% CAGR vs 25.0%).

JDS Uniphase Corporation (JDSU) was an American company that designed and manufactured products for optical communications networks, communications test and measurement equipment, lasers, optical solutions for authentication and decorative applications, and other custom optics. It was headquartered in Milpitas, California. In August 2015, JDSU split into two different companies – Viavi Solutions and Lumentum Holdings.

Neurocrine Biosciences, Inc. is an American biopharmaceutical company founded in 1992. It is headquartered in San Diego, California, and led by CEO Kyle Gano as of October 11, 2024. Neurocrine develops treatments for neurological and endocrine-related diseases and disorders. In 2017, the company's drug valbenazine (Ingrezza) was approved in the US to treat adults with tardive dyskinesia (TD).

LITE vs NBIX — Head-to-Head

Bigger by revenue
NBIX
NBIX
1.2× larger
NBIX
$805.5M
$665.5M
LITE
Growing faster (revenue YoY)
LITE
LITE
+37.1% gap
LITE
65.5%
28.3%
NBIX
Higher net margin
NBIX
NBIX
7.3% more per $
NBIX
19.1%
11.8%
LITE
More free cash flow
NBIX
NBIX
$342.9M more FCF
NBIX
$386.0M
$43.1M
LITE
Faster 2-yr revenue CAGR
LITE
LITE
Annualised
LITE
34.8%
25.0%
NBIX

Income Statement — Q2 FY2026 vs Q4 FY2025

Metric
LITE
LITE
NBIX
NBIX
Revenue
$665.5M
$805.5M
Net Profit
$78.2M
$153.7M
Gross Margin
36.1%
97.8%
Operating Margin
9.7%
26.2%
Net Margin
11.8%
19.1%
Revenue YoY
65.5%
28.3%
Net Profit YoY
228.4%
49.1%
EPS (diluted)
$0.89
$1.49

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
LITE
LITE
NBIX
NBIX
Q4 25
$665.5M
$805.5M
Q3 25
$533.8M
$794.9M
Q2 25
$480.7M
$687.5M
Q1 25
$425.2M
$572.6M
Q4 24
$402.2M
$627.7M
Q3 24
$336.9M
$622.1M
Q2 24
$308.3M
$590.2M
Q1 24
$366.5M
$515.3M
Net Profit
LITE
LITE
NBIX
NBIX
Q4 25
$78.2M
$153.7M
Q3 25
$4.2M
$209.5M
Q2 25
$213.3M
$107.5M
Q1 25
$-44.1M
$7.9M
Q4 24
$-60.9M
$103.1M
Q3 24
$-82.4M
$129.8M
Q2 24
$-252.5M
$65.0M
Q1 24
$-127.0M
$43.4M
Gross Margin
LITE
LITE
NBIX
NBIX
Q4 25
36.1%
97.8%
Q3 25
34.0%
98.2%
Q2 25
33.3%
98.4%
Q1 25
28.8%
98.4%
Q4 24
24.8%
98.5%
Q3 24
23.1%
98.7%
Q2 24
16.6%
98.4%
Q1 24
16.2%
98.5%
Operating Margin
LITE
LITE
NBIX
NBIX
Q4 25
9.7%
26.2%
Q3 25
1.3%
30.1%
Q2 25
-1.7%
21.2%
Q1 25
-8.9%
4.1%
Q4 24
-12.8%
22.6%
Q3 24
-24.5%
29.5%
Q2 24
-43.3%
24.6%
Q1 24
-31.3%
19.3%
Net Margin
LITE
LITE
NBIX
NBIX
Q4 25
11.8%
19.1%
Q3 25
0.8%
26.4%
Q2 25
44.4%
15.6%
Q1 25
-10.4%
1.4%
Q4 24
-15.1%
16.4%
Q3 24
-24.5%
20.9%
Q2 24
-81.9%
11.0%
Q1 24
-34.7%
8.4%
EPS (diluted)
LITE
LITE
NBIX
NBIX
Q4 25
$0.89
$1.49
Q3 25
$0.05
$2.04
Q2 25
$3.10
$1.06
Q1 25
$-0.64
$0.08
Q4 24
$-0.88
$1.00
Q3 24
$-1.21
$1.24
Q2 24
$-3.75
$0.63
Q1 24
$-1.88
$0.42

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
LITE
LITE
NBIX
NBIX
Cash + ST InvestmentsLiquidity on hand
$1.2B
$713.0M
Total DebtLower is stronger
Stockholders' EquityBook value
$846.6M
$3.3B
Total Assets
$4.8B
$4.6B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
LITE
LITE
NBIX
NBIX
Q4 25
$1.2B
$713.0M
Q3 25
$1.1B
$340.2M
Q2 25
$877.1M
$264.0M
Q1 25
$866.7M
$194.1M
Q4 24
$896.7M
$233.0M
Q3 24
$916.1M
$349.1M
Q2 24
$887.0M
$139.7M
Q1 24
$870.9M
$396.3M
Stockholders' Equity
LITE
LITE
NBIX
NBIX
Q4 25
$846.6M
$3.3B
Q3 25
$780.8M
$3.0B
Q2 25
$1.1B
$2.7B
Q1 25
$879.5M
$2.5B
Q4 24
$872.3M
$2.6B
Q3 24
$895.9M
$2.7B
Q2 24
$957.3M
$2.5B
Q1 24
$1.2B
$2.4B
Total Assets
LITE
LITE
NBIX
NBIX
Q4 25
$4.8B
$4.6B
Q3 25
$4.6B
$4.3B
Q2 25
$4.2B
$3.9B
Q1 25
$4.0B
$3.7B
Q4 24
$4.0B
$3.7B
Q3 24
$4.0B
$3.5B
Q2 24
$3.9B
$3.3B
Q1 24
$4.2B
$3.5B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
LITE
LITE
NBIX
NBIX
Operating Cash FlowLast quarter
$126.7M
$388.4M
Free Cash FlowOCF − Capex
$43.1M
$386.0M
FCF MarginFCF / Revenue
6.5%
47.9%
Capex IntensityCapex / Revenue
12.6%
0.3%
Cash ConversionOCF / Net Profit
1.62×
2.53×
TTM Free Cash FlowTrailing 4 quarters
$-29.5M
$743.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
LITE
LITE
NBIX
NBIX
Q4 25
$126.7M
$388.4M
Q3 25
$57.9M
$227.5M
Q2 25
$64.0M
$102.0M
Q1 25
$-1.6M
$64.8M
Q4 24
$24.3M
$242.5M
Q3 24
$39.6M
$158.0M
Q2 24
$35.5M
$64.6M
Q1 24
$-7.0M
$130.3M
Free Cash Flow
LITE
LITE
NBIX
NBIX
Q4 25
$43.1M
$386.0M
Q3 25
$-18.3M
$214.3M
Q2 25
$10.1M
$89.5M
Q1 25
$-64.4M
$54.1M
Q4 24
$-15.9M
$235.2M
Q3 24
$-34.5M
$149.9M
Q2 24
$10.9M
$53.0M
Q1 24
$-26.6M
$119.1M
FCF Margin
LITE
LITE
NBIX
NBIX
Q4 25
6.5%
47.9%
Q3 25
-3.4%
27.0%
Q2 25
2.1%
13.0%
Q1 25
-15.1%
9.4%
Q4 24
-4.0%
37.5%
Q3 24
-10.2%
24.1%
Q2 24
3.5%
9.0%
Q1 24
-7.3%
23.1%
Capex Intensity
LITE
LITE
NBIX
NBIX
Q4 25
12.6%
0.3%
Q3 25
14.3%
1.7%
Q2 25
11.2%
1.8%
Q1 25
14.8%
1.9%
Q4 24
10.0%
1.2%
Q3 24
22.0%
1.3%
Q2 24
8.0%
2.0%
Q1 24
5.3%
2.2%
Cash Conversion
LITE
LITE
NBIX
NBIX
Q4 25
1.62×
2.53×
Q3 25
13.79×
1.09×
Q2 25
0.30×
0.95×
Q1 25
8.20×
Q4 24
2.35×
Q3 24
1.22×
Q2 24
0.99×
Q1 24
3.00×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

LITE
LITE

Components$443.7M67%
Systems$221.8M33%

NBIX
NBIX

INGREZZA Net Product Sales$653.8M81%
CRENESSITY Net Product Sales$135.4M17%
Other Income$12.6M2%
Collaboration Revenue$7.2M1%

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