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Side-by-side financial comparison of Lantheus Holdings, Inc. (LNTH) and OSI SYSTEMS INC (OSIS). Click either name above to swap in a different company.

OSI SYSTEMS INC is the larger business by last-quarter revenue ($464.1M vs $406.8M, roughly 1.1× Lantheus Holdings, Inc.). Lantheus Holdings, Inc. runs the higher net margin — 13.3% vs 8.3%, a 5.0% gap on every dollar of revenue. On growth, OSI SYSTEMS INC posted the faster year-over-year revenue change (10.5% vs 4.0%). Lantheus Holdings, Inc. produced more free cash flow last quarter ($81.4M vs $55.5M). Over the past eight quarters, OSI SYSTEMS INC's revenue compounded faster (7.0% CAGR vs 4.9%).

Lantheus Holdings, Inc. is a global healthcare firm specializing in the development, manufacturing and commercialization of innovative diagnostic imaging agents and related solutions. Its offerings cover core medical segments including oncology, cardiology and urology, with primary markets across North America and other key global regions.

OSI Systems, Inc. is an American company based in California that develops and markets security and inspection systems such as airport security X-ray machines and metal detectors, medical monitoring and anesthesia systems, and optoelectronic devices. As of June 2010, the company employs approximately 3,180 personnel globally and includes subsidiary companies Spacelabs Healthcare, Rapiscan Systems and OSI Optoelectronics.

LNTH vs OSIS — Head-to-Head

Bigger by revenue
OSIS
OSIS
1.1× larger
OSIS
$464.1M
$406.8M
LNTH
Growing faster (revenue YoY)
OSIS
OSIS
+6.5% gap
OSIS
10.5%
4.0%
LNTH
Higher net margin
LNTH
LNTH
5.0% more per $
LNTH
13.3%
8.3%
OSIS
More free cash flow
LNTH
LNTH
$25.9M more FCF
LNTH
$81.4M
$55.5M
OSIS
Faster 2-yr revenue CAGR
OSIS
OSIS
Annualised
OSIS
7.0%
4.9%
LNTH

Income Statement — Q4 FY2025 vs Q2 FY2026

Metric
LNTH
LNTH
OSIS
OSIS
Revenue
$406.8M
$464.1M
Net Profit
$54.1M
$38.7M
Gross Margin
59.2%
32.7%
Operating Margin
19.0%
12.7%
Net Margin
13.3%
8.3%
Revenue YoY
4.0%
10.5%
Net Profit YoY
558.8%
2.3%
EPS (diluted)
$0.86
$2.22

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
LNTH
LNTH
OSIS
OSIS
Q4 25
$406.8M
$464.1M
Q3 25
$384.0M
$384.6M
Q2 25
$378.0M
$505.0M
Q1 25
$372.8M
$444.4M
Q4 24
$391.1M
$419.8M
Q3 24
$378.7M
$344.0M
Q2 24
$394.1M
$480.9M
Q1 24
$370.0M
$405.4M
Net Profit
LNTH
LNTH
OSIS
OSIS
Q4 25
$54.1M
$38.7M
Q3 25
$27.8M
$20.6M
Q2 25
$78.8M
$52.7M
Q1 25
$72.9M
$41.1M
Q4 24
$-11.8M
$37.8M
Q3 24
$131.1M
$17.9M
Q2 24
$62.1M
$44.7M
Q1 24
$131.1M
$34.0M
Gross Margin
LNTH
LNTH
OSIS
OSIS
Q4 25
59.2%
32.7%
Q3 25
57.9%
32.0%
Q2 25
63.8%
33.3%
Q1 25
63.8%
33.8%
Q4 24
63.5%
35.1%
Q3 24
63.9%
35.3%
Q2 24
64.9%
32.1%
Q1 24
65.4%
33.6%
Operating Margin
LNTH
LNTH
OSIS
OSIS
Q4 25
19.0%
12.7%
Q3 25
11.4%
8.6%
Q2 25
23.3%
14.5%
Q1 25
27.4%
12.7%
Q4 24
29.1%
13.8%
Q3 24
35.3%
8.8%
Q2 24
26.1%
13.1%
Q1 24
28.8%
12.7%
Net Margin
LNTH
LNTH
OSIS
OSIS
Q4 25
13.3%
8.3%
Q3 25
7.2%
5.3%
Q2 25
20.8%
10.4%
Q1 25
19.6%
9.3%
Q4 24
-3.0%
9.0%
Q3 24
34.6%
5.2%
Q2 24
15.8%
9.3%
Q1 24
35.4%
8.4%
EPS (diluted)
LNTH
LNTH
OSIS
OSIS
Q4 25
$0.86
$2.22
Q3 25
$0.41
$1.18
Q2 25
$1.12
$3.04
Q1 25
$1.02
$2.40
Q4 24
$-0.18
$2.22
Q3 24
$1.79
$1.05
Q2 24
$0.88
$2.57
Q1 24
$1.87
$1.95

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
LNTH
LNTH
OSIS
OSIS
Cash + ST InvestmentsLiquidity on hand
$359.1M
$336.7M
Total DebtLower is stronger
$568.7M
$1.0B
Stockholders' EquityBook value
$1.1B
$845.5M
Total Assets
$2.2B
$2.5B
Debt / EquityLower = less leverage
0.52×
1.19×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
LNTH
LNTH
OSIS
OSIS
Q4 25
$359.1M
$336.7M
Q3 25
$382.0M
$124.4M
Q2 25
$695.6M
$106.4M
Q1 25
$938.5M
$95.8M
Q4 24
$912.8M
$101.6M
Q3 24
$866.4M
$85.1M
Q2 24
$757.0M
$95.4M
Q1 24
$718.3M
$101.4M
Total Debt
LNTH
LNTH
OSIS
OSIS
Q4 25
$568.7M
$1.0B
Q3 25
$567.9M
$442.2M
Q2 25
$566.8M
$471.6M
Q1 25
$566.1M
$473.2M
Q4 24
$565.3M
$474.8M
Q3 24
$613.0K
$476.3M
Q2 24
$563.2M
$137.6M
Q1 24
$562.5M
Stockholders' Equity
LNTH
LNTH
OSIS
OSIS
Q4 25
$1.1B
$845.5M
Q3 25
$1.1B
$946.0M
Q2 25
$1.2B
$951.1M
Q1 25
$1.2B
$879.3M
Q4 24
$1.1B
$825.8M
Q3 24
$1.2B
$786.5M
Q2 24
$1.0B
$863.5M
Q1 24
$945.5M
$813.4M
Total Assets
LNTH
LNTH
OSIS
OSIS
Q4 25
$2.2B
$2.5B
Q3 25
$2.3B
$2.3B
Q2 25
$2.1B
$2.2B
Q1 25
$2.1B
$2.1B
Q4 24
$2.0B
$2.1B
Q3 24
$2.0B
$2.1B
Q2 24
$1.9B
$1.9B
Q1 24
$1.8B
$1.8B
Debt / Equity
LNTH
LNTH
OSIS
OSIS
Q4 25
0.52×
1.19×
Q3 25
0.51×
0.47×
Q2 25
0.49×
0.50×
Q1 25
0.49×
0.54×
Q4 24
0.52×
0.57×
Q3 24
0.00×
0.61×
Q2 24
0.55×
0.16×
Q1 24
0.59×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
LNTH
LNTH
OSIS
OSIS
Operating Cash FlowLast quarter
$90.2M
$62.2M
Free Cash FlowOCF − Capex
$81.4M
$55.5M
FCF MarginFCF / Revenue
20.0%
12.0%
Capex IntensityCapex / Revenue
2.2%
1.4%
Cash ConversionOCF / Net Profit
1.67×
1.61×
TTM Free Cash FlowTrailing 4 quarters
$354.1M
$137.2M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
LNTH
LNTH
OSIS
OSIS
Q4 25
$90.2M
$62.2M
Q3 25
$105.3M
$17.1M
Q2 25
$87.1M
$562.0K
Q1 25
$107.6M
$81.6M
Q4 24
$157.7M
$52.5M
Q3 24
$175.1M
$-37.2M
Q2 24
$84.7M
$-29.0M
Q1 24
$127.2M
$-52.1M
Free Cash Flow
LNTH
LNTH
OSIS
OSIS
Q4 25
$81.4M
$55.5M
Q3 25
$94.7M
$10.1M
Q2 25
$79.1M
$-5.6M
Q1 25
$98.8M
$77.1M
Q4 24
$141.4M
$47.1M
Q3 24
$159.3M
$-44.9M
Q2 24
$73.5M
$-37.5M
Q1 24
$119.0M
$-57.0M
FCF Margin
LNTH
LNTH
OSIS
OSIS
Q4 25
20.0%
12.0%
Q3 25
24.7%
2.6%
Q2 25
20.9%
-1.1%
Q1 25
26.5%
17.4%
Q4 24
36.1%
11.2%
Q3 24
42.0%
-13.0%
Q2 24
18.7%
-7.8%
Q1 24
32.2%
-14.1%
Capex Intensity
LNTH
LNTH
OSIS
OSIS
Q4 25
2.2%
1.4%
Q3 25
2.8%
1.8%
Q2 25
2.1%
1.2%
Q1 25
2.3%
1.0%
Q4 24
4.2%
1.3%
Q3 24
4.2%
2.2%
Q2 24
2.8%
1.8%
Q1 24
2.2%
1.2%
Cash Conversion
LNTH
LNTH
OSIS
OSIS
Q4 25
1.67×
1.61×
Q3 25
3.79×
0.83×
Q2 25
1.11×
0.01×
Q1 25
1.47×
1.98×
Q4 24
1.39×
Q3 24
1.34×
-2.07×
Q2 24
1.36×
-0.65×
Q1 24
0.97×
-1.53×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

LNTH
LNTH

Radiopharmaceutical Oncology$240.2M59%
Definity$85.3M21%
Strategic Partnerships And Other$23.3M6%
Techne Lite$21.0M5%
Licenseand Royalty Revenues$17.4M4%
Other$13.6M3%
Other Precision Diagnostics$5.9M1%

OSIS
OSIS

Security Division$334.7M72%
Optoelectronics And Manufacturing Division$92.8M20%
Healthcare Division$36.5M8%

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