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Side-by-side financial comparison of ManpowerGroup Inc. (MAN) and Vertex Pharmaceuticals (VRTX). Click either name above to swap in a different company.

ManpowerGroup Inc. is the larger business by last-quarter revenue ($4.7B vs $3.2B, roughly 1.5× Vertex Pharmaceuticals). Vertex Pharmaceuticals runs the higher net margin — 37.3% vs 0.6%, a 36.7% gap on every dollar of revenue. On growth, Vertex Pharmaceuticals posted the faster year-over-year revenue change (9.5% vs 7.1%). Vertex Pharmaceuticals produced more free cash flow last quarter ($348.6M vs $168.0M). Over the past eight quarters, Vertex Pharmaceuticals's revenue compounded faster (8.9% CAGR vs 3.5%).

ManpowerGroup is an American multinational corporation headquartered in Milwaukee, Wisconsin. Founded in 1948 by Elmer Winter and Aaron Scheinfeld, ManpowerGroup is the third-largest staffing firm in the world behind Swiss firm Adecco and Dutch firm Randstad NV. The company provides administrative & support services, professional services, and business services through its four primary brands: Manpower, Experis, Right Management, and ManpowerGroup Solutions.

Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, Oxfordshire, England.

MAN vs VRTX — Head-to-Head

Bigger by revenue
MAN
MAN
1.5× larger
MAN
$4.7B
$3.2B
VRTX
Growing faster (revenue YoY)
VRTX
VRTX
+2.4% gap
VRTX
9.5%
7.1%
MAN
Higher net margin
VRTX
VRTX
36.7% more per $
VRTX
37.3%
0.6%
MAN
More free cash flow
VRTX
VRTX
$180.6M more FCF
VRTX
$348.6M
$168.0M
MAN
Faster 2-yr revenue CAGR
VRTX
VRTX
Annualised
VRTX
8.9%
3.5%
MAN

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
MAN
MAN
VRTX
VRTX
Revenue
$4.7B
$3.2B
Net Profit
$30.2M
$1.2B
Gross Margin
16.3%
85.4%
Operating Margin
1.7%
37.8%
Net Margin
0.6%
37.3%
Revenue YoY
7.1%
9.5%
Net Profit YoY
34.2%
30.5%
EPS (diluted)
$0.65
$4.64

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
MAN
MAN
VRTX
VRTX
Q4 25
$4.7B
$3.2B
Q3 25
$4.6B
$3.1B
Q2 25
$4.5B
$3.0B
Q1 25
$4.1B
$2.8B
Q4 24
$4.4B
$2.9B
Q3 24
$4.5B
$2.8B
Q2 24
$4.5B
$2.6B
Q1 24
$4.4B
$2.7B
Net Profit
MAN
MAN
VRTX
VRTX
Q4 25
$30.2M
$1.2B
Q3 25
$18.0M
$1.1B
Q2 25
$-67.1M
$1.0B
Q1 25
$5.6M
$646.3M
Q4 24
$22.5M
$913.0M
Q3 24
$22.8M
$1.0B
Q2 24
$60.1M
$-3.6B
Q1 24
$39.7M
$1.1B
Gross Margin
MAN
MAN
VRTX
VRTX
Q4 25
16.3%
85.4%
Q3 25
16.6%
86.5%
Q2 25
16.9%
86.3%
Q1 25
17.1%
86.9%
Q4 24
17.2%
85.5%
Q3 24
17.3%
85.8%
Q2 24
17.4%
85.9%
Q1 24
17.3%
87.3%
Operating Margin
MAN
MAN
VRTX
VRTX
Q4 25
1.7%
37.8%
Q3 25
1.4%
38.6%
Q2 25
-0.6%
38.8%
Q1 25
0.7%
22.7%
Q4 24
1.6%
35.2%
Q3 24
1.6%
40.3%
Q2 24
2.2%
-132.9%
Q1 24
1.5%
42.4%
Net Margin
MAN
MAN
VRTX
VRTX
Q4 25
0.6%
37.3%
Q3 25
0.4%
35.2%
Q2 25
-1.5%
34.8%
Q1 25
0.1%
23.3%
Q4 24
0.5%
31.4%
Q3 24
0.5%
37.7%
Q2 24
1.3%
-135.8%
Q1 24
0.9%
40.9%
EPS (diluted)
MAN
MAN
VRTX
VRTX
Q4 25
$0.65
$4.64
Q3 25
$0.38
$4.20
Q2 25
$-1.44
$3.99
Q1 25
$0.12
$2.49
Q4 24
$0.49
$3.62
Q3 24
$0.47
$4.01
Q2 24
$1.24
$-13.92
Q1 24
$0.81
$4.21

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
MAN
MAN
VRTX
VRTX
Cash + ST InvestmentsLiquidity on hand
$871.0M
$6.6B
Total DebtLower is stronger
$1.1B
Stockholders' EquityBook value
$2.1B
$18.7B
Total Assets
$9.2B
$25.6B
Debt / EquityLower = less leverage
0.51×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
MAN
MAN
VRTX
VRTX
Q4 25
$871.0M
$6.6B
Q3 25
$274.6M
$6.3B
Q2 25
$289.8M
$6.4B
Q1 25
$395.0M
$6.2B
Q4 24
$509.4M
$6.1B
Q3 24
$410.9M
$6.5B
Q2 24
$468.9M
$5.8B
Q1 24
$604.8M
$10.2B
Total Debt
MAN
MAN
VRTX
VRTX
Q4 25
$1.1B
Q3 25
$468.3M
Q2 25
$470.3M
Q1 25
$971.4M
Q4 24
$929.4M
Q3 24
$999.7M
Q2 24
$961.7M
Q1 24
$968.9M
Stockholders' Equity
MAN
MAN
VRTX
VRTX
Q4 25
$2.1B
$18.7B
Q3 25
$2.0B
$17.3B
Q2 25
$2.0B
$17.2B
Q1 25
$2.1B
$16.5B
Q4 24
$2.1B
$16.4B
Q3 24
$2.2B
$15.6B
Q2 24
$2.1B
$14.8B
Q1 24
$2.2B
$18.5B
Total Assets
MAN
MAN
VRTX
VRTX
Q4 25
$9.2B
$25.6B
Q3 25
$8.4B
$24.9B
Q2 25
$8.5B
$24.0B
Q1 25
$8.0B
$22.9B
Q4 24
$8.2B
$22.5B
Q3 24
$8.5B
$22.2B
Q2 24
$8.5B
$20.1B
Q1 24
$8.5B
$23.9B
Debt / Equity
MAN
MAN
VRTX
VRTX
Q4 25
0.51×
Q3 25
0.23×
Q2 25
0.24×
Q1 25
0.46×
Q4 24
0.44×
Q3 24
0.46×
Q2 24
0.45×
Q1 24
0.45×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
MAN
MAN
VRTX
VRTX
Operating Cash FlowLast quarter
$178.9M
$498.0M
Free Cash FlowOCF − Capex
$168.0M
$348.6M
FCF MarginFCF / Revenue
3.6%
10.9%
Capex IntensityCapex / Revenue
0.2%
4.7%
Cash ConversionOCF / Net Profit
5.92×
0.42×
TTM Free Cash FlowTrailing 4 quarters
$-161.4M
$3.2B

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
MAN
MAN
VRTX
VRTX
Q4 25
$178.9M
$498.0M
Q3 25
$59.8M
$1.2B
Q2 25
$-189.6M
$1.1B
Q1 25
$-153.2M
$818.9M
Q4 24
$247.6M
$584.6M
Q3 24
$83.5M
$1.4B
Q2 24
$-137.9M
$-3.8B
Q1 24
$116.0M
$1.3B
Free Cash Flow
MAN
MAN
VRTX
VRTX
Q4 25
$168.0M
$348.6M
Q3 25
$44.7M
$1.1B
Q2 25
$-207.2M
$927.4M
Q1 25
$-166.9M
$778.2M
Q4 24
$236.3M
$492.0M
Q3 24
$67.4M
$1.3B
Q2 24
$-149.8M
$-3.8B
Q1 24
$104.2M
$1.2B
FCF Margin
MAN
MAN
VRTX
VRTX
Q4 25
3.6%
10.9%
Q3 25
1.0%
37.0%
Q2 25
-4.6%
31.3%
Q1 25
-4.1%
28.1%
Q4 24
5.4%
16.9%
Q3 24
1.5%
47.0%
Q2 24
-3.3%
-144.5%
Q1 24
2.4%
46.0%
Capex Intensity
MAN
MAN
VRTX
VRTX
Q4 25
0.2%
4.7%
Q3 25
0.3%
3.3%
Q2 25
0.4%
4.9%
Q1 25
0.3%
1.5%
Q4 24
0.3%
3.2%
Q3 24
0.4%
2.4%
Q2 24
0.3%
2.6%
Q1 24
0.3%
2.5%
Cash Conversion
MAN
MAN
VRTX
VRTX
Q4 25
5.92×
0.42×
Q3 25
3.32×
1.15×
Q2 25
1.04×
Q1 25
-27.36×
1.27×
Q4 24
11.00×
0.64×
Q3 24
3.66×
1.31×
Q2 24
-2.29×
Q1 24
2.92×
1.19×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

MAN
MAN

Other$2.4B52%
Transferred Over Time$1.1B24%
Staffingand Interim$1.0B22%
Productsand Services Other$50.8M1%
Permanent Recruitment$37.5M1%
Outcome Based Solutionsand Consulting$20.7M0%
Transferred At Point In Time$20.4M0%

VRTX
VRTX

TRIKAFTAKAFTRIO$2.6B81%
ALYFTREK$380.1M12%
Manufactured Product Other$237.4M7%

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