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Side-by-side financial comparison of MADRIGAL PHARMACEUTICALS, INC. (MDGL) and SAFETY INSURANCE GROUP INC (SAFT). Click either name above to swap in a different company.

MADRIGAL PHARMACEUTICALS, INC. is the larger business by last-quarter revenue ($321.1M vs $319.3M, roughly 1.0× SAFETY INSURANCE GROUP INC). SAFETY INSURANCE GROUP INC runs the higher net margin — 6.3% vs -18.2%, a 24.5% gap on every dollar of revenue. On growth, MADRIGAL PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (210.8% vs 11.4%). SAFETY INSURANCE GROUP INC produced more free cash flow last quarter ($192.0M vs $-133.8M).

Intercept Pharmaceuticals, Inc. is an American biopharmaceutical company incorporated in 2002, focusing on the development of novel synthetic bile acid analogs to treat chronic liver diseases, such as primary biliary cirrhosis (PBC) now called primary biliary cholangitis, non-alcoholic fatty liver disease, cirrhosis, portal hypertension, primary sclerosing cholangitis and also the intestinal disorder, bile acid diarrhea.

Nationwide Mutual Insurance Company and affiliated companies, commonly shortened to Nationwide, is a group of large U.S. insurance and financial services companies based in Columbus, Ohio. The company also operates regional headquarters in Scottsdale, Arizona and Des Moines, Iowa. Nationwide currently has approximately 24,000 employees, and is ranked No. 72 in the 2025 Fortune 500 list.

MDGL vs SAFT — Head-to-Head

Bigger by revenue
MDGL
MDGL
1.0× larger
MDGL
$321.1M
$319.3M
SAFT
Growing faster (revenue YoY)
MDGL
MDGL
+199.4% gap
MDGL
210.8%
11.4%
SAFT
Higher net margin
SAFT
SAFT
24.5% more per $
SAFT
6.3%
-18.2%
MDGL
More free cash flow
SAFT
SAFT
$325.8M more FCF
SAFT
$192.0M
$-133.8M
MDGL

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
MDGL
MDGL
SAFT
SAFT
Revenue
$321.1M
$319.3M
Net Profit
$-58.6M
$20.1M
Gross Margin
Operating Margin
-18.6%
8.0%
Net Margin
-18.2%
6.3%
Revenue YoY
210.8%
11.4%
Net Profit YoY
1.4%
147.3%
EPS (diluted)
$-2.55
$1.36

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
MDGL
MDGL
SAFT
SAFT
Q4 25
$321.1M
$319.3M
Q3 25
$287.3M
$326.6M
Q2 25
$212.8M
$316.3M
Q1 25
$137.3M
$301.4M
Q4 24
$103.3M
$286.7M
Q3 24
$62.2M
$295.3M
Q2 24
$269.8M
Q1 24
$0
$268.2M
Net Profit
MDGL
MDGL
SAFT
SAFT
Q4 25
$-58.6M
$20.1M
Q3 25
$-114.2M
$28.3M
Q2 25
$-42.3M
$28.9M
Q1 25
$-73.2M
$21.9M
Q4 24
$-59.4M
$8.1M
Q3 24
$-107.0M
$25.9M
Q2 24
$16.6M
Q1 24
$-147.5M
$20.1M
Gross Margin
MDGL
MDGL
SAFT
SAFT
Q4 25
Q3 25
Q2 25
Q1 25
96.7%
Q4 24
Q3 24
Q2 24
Q1 24
Operating Margin
MDGL
MDGL
SAFT
SAFT
Q4 25
-18.6%
8.0%
Q3 25
-39.7%
11.1%
Q2 25
-22.2%
11.6%
Q1 25
-57.8%
9.4%
Q4 24
-64.8%
3.5%
Q3 24
-187.1%
11.1%
Q2 24
7.9%
Q1 24
9.5%
Net Margin
MDGL
MDGL
SAFT
SAFT
Q4 25
-18.2%
6.3%
Q3 25
-39.8%
8.7%
Q2 25
-19.9%
9.1%
Q1 25
-53.4%
7.3%
Q4 24
-57.5%
2.8%
Q3 24
-172.0%
8.8%
Q2 24
6.2%
Q1 24
7.5%
EPS (diluted)
MDGL
MDGL
SAFT
SAFT
Q4 25
$-2.55
$1.36
Q3 25
$-5.08
$1.91
Q2 25
$-1.90
$1.95
Q1 25
$-3.32
$1.48
Q4 24
$-2.50
$0.56
Q3 24
$-4.92
$1.73
Q2 24
$1.13
Q1 24
$-7.38
$1.36

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
MDGL
MDGL
SAFT
SAFT
Cash + ST InvestmentsLiquidity on hand
$198.7M
$73.9M
Total DebtLower is stronger
$339.9M
$50.0M
Stockholders' EquityBook value
$602.7M
$892.3M
Total Assets
$1.3B
$2.5B
Debt / EquityLower = less leverage
0.56×
0.06×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
MDGL
MDGL
SAFT
SAFT
Q4 25
$198.7M
$73.9M
Q3 25
$295.7M
$56.2M
Q2 25
$186.2M
$49.4M
Q1 25
$183.6M
$64.7M
Q4 24
$100.0M
$59.0M
Q3 24
$232.7M
$82.3M
Q2 24
$44.6M
Q1 24
$622.5M
$30.8M
Total Debt
MDGL
MDGL
SAFT
SAFT
Q4 25
$339.9M
$50.0M
Q3 25
$339.8M
$30.0M
Q2 25
$118.4M
$30.0M
Q1 25
$118.0M
$30.0M
Q4 24
$117.6M
Q3 24
$117.1M
Q2 24
Q1 24
$116.1M
Stockholders' Equity
MDGL
MDGL
SAFT
SAFT
Q4 25
$602.7M
$892.3M
Q3 25
$625.7M
$899.6M
Q2 25
$696.0M
$873.3M
Q1 25
$710.6M
$850.7M
Q4 24
$754.4M
$828.5M
Q3 24
$777.2M
$851.4M
Q2 24
$810.2M
Q1 24
$850.8M
$807.1M
Total Assets
MDGL
MDGL
SAFT
SAFT
Q4 25
$1.3B
$2.5B
Q3 25
$1.4B
$2.4B
Q2 25
$1.0B
$2.4B
Q1 25
$996.6M
$2.3B
Q4 24
$1.0B
$2.3B
Q3 24
$1.1B
$2.3B
Q2 24
$2.2B
Q1 24
$1.1B
$2.1B
Debt / Equity
MDGL
MDGL
SAFT
SAFT
Q4 25
0.56×
0.06×
Q3 25
0.54×
0.03×
Q2 25
0.17×
0.03×
Q1 25
0.17×
0.04×
Q4 24
0.16×
Q3 24
0.15×
Q2 24
Q1 24
0.14×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
MDGL
MDGL
SAFT
SAFT
Operating Cash FlowLast quarter
$-133.5M
$194.5M
Free Cash FlowOCF − Capex
$-133.8M
$192.0M
FCF MarginFCF / Revenue
-41.7%
60.1%
Capex IntensityCapex / Revenue
0.1%
0.8%
Cash ConversionOCF / Net Profit
9.67×
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
MDGL
MDGL
SAFT
SAFT
Q4 25
$-133.5M
$194.5M
Q3 25
$79.8M
$85.5M
Q2 25
$-47.1M
$32.3M
Q1 25
$-88.9M
$3.2M
Q4 24
$-104.5M
$128.7M
Q3 24
$-67.0M
$73.8M
Q2 24
$25.6M
Q1 24
$-149.2M
$-21.1M
Free Cash Flow
MDGL
MDGL
SAFT
SAFT
Q4 25
$-133.8M
$192.0M
Q3 25
$79.0M
Q2 25
$32.3M
Q1 25
$2.8M
Q4 24
$-104.7M
$124.3M
Q3 24
$-67.8M
$73.2M
Q2 24
$25.0M
Q1 24
$-149.5M
$-24.2M
FCF Margin
MDGL
MDGL
SAFT
SAFT
Q4 25
-41.7%
60.1%
Q3 25
27.5%
Q2 25
10.2%
Q1 25
0.9%
Q4 24
-101.3%
43.4%
Q3 24
-109.0%
24.8%
Q2 24
9.3%
Q1 24
-9.0%
Capex Intensity
MDGL
MDGL
SAFT
SAFT
Q4 25
0.1%
0.8%
Q3 25
0.3%
0.0%
Q2 25
0.0%
0.0%
Q1 25
0.0%
0.1%
Q4 24
0.2%
1.5%
Q3 24
1.3%
0.2%
Q2 24
0.2%
Q1 24
1.1%
Cash Conversion
MDGL
MDGL
SAFT
SAFT
Q4 25
9.67×
Q3 25
3.02×
Q2 25
1.12×
Q1 25
0.14×
Q4 24
15.83×
Q3 24
2.85×
Q2 24
1.54×
Q1 24
-1.05×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

MDGL
MDGL

Rebates Customer Fees Credits Co Pay Assistance And Other$208.5M65%
Other$76.0M24%
Chargebacks Discounts For Prompt Pay And Other Allowances$36.6M11%

SAFT
SAFT

Segment breakdown not available.

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