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Side-by-side financial comparison of MeiraGTx Holdings plc (MGTX) and Pelthos Therapeutics Inc. (PTHS). Click either name above to swap in a different company.

MeiraGTx Holdings plc is the larger business by last-quarter revenue ($410.0K vs $294.0K, roughly 1.4× Pelthos Therapeutics Inc.). Pelthos Therapeutics Inc. runs the higher net margin — -5523.1% vs -12320.2%, a 6797.1% gap on every dollar of revenue.

MeiraGTx Holdings plc is a clinical-stage biotechnology firm specializing in the research, development and commercialization of transformative gene therapies. Its core pipeline targets rare ophthalmic conditions, neurodegenerative disorders, and salivary gland diseases, serving patients across global markets with operations in the U.S. and European Union.

Pelthos Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on discovering, developing, and commercializing targeted therapies for rare metabolic and endocrine diseases with significant unmet medical needs. It operates primarily across North America and Europe, with a pipeline of novel drug candidates addressing underserved patient populations.

MGTX vs PTHS — Head-to-Head

Bigger by revenue
MGTX
MGTX
1.4× larger
MGTX
$410.0K
$294.0K
PTHS
Higher net margin
PTHS
PTHS
6797.1% more per $
PTHS
-5523.1%
-12320.2%
MGTX

Income Statement — Q3 FY2025 vs Q3 FY2025

Metric
MGTX
MGTX
PTHS
PTHS
Revenue
$410.0K
$294.0K
Net Profit
$-50.5M
$-16.2M
Gross Margin
-687.8%
Operating Margin
-11232.0%
-5225.2%
Net Margin
-12320.2%
-5523.1%
Revenue YoY
-96.2%
Net Profit YoY
-28.4%
-858.0%
EPS (diluted)
$-0.62
$-5.30

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
MGTX
MGTX
PTHS
PTHS
Q3 25
$410.0K
$294.0K
Q2 25
$3.7M
Q4 24
$21.4M
Q3 24
$10.9M
Q2 24
$282.0K
Q1 24
$697.0K
Q4 23
$2.0M
Q3 23
$5.1M
Net Profit
MGTX
MGTX
PTHS
PTHS
Q3 25
$-50.5M
$-16.2M
Q2 25
$-38.8M
Q4 24
$-39.4M
Q3 24
$-39.3M
Q2 24
$-48.6M
Q1 24
$-20.4M
Q4 23
Q3 23
$-44.3M
Gross Margin
MGTX
MGTX
PTHS
PTHS
Q3 25
-687.8%
Q2 25
Q4 24
Q3 24
Q2 24
Q1 24
Q4 23
Q3 23
Operating Margin
MGTX
MGTX
PTHS
PTHS
Q3 25
-11232.0%
-5225.2%
Q2 25
-1213.6%
Q4 24
-147.2%
Q3 24
-367.0%
Q2 24
-16279.8%
Q1 24
-6710.5%
Q4 23
Q3 23
-642.0%
Net Margin
MGTX
MGTX
PTHS
PTHS
Q3 25
-12320.2%
-5523.1%
Q2 25
-1051.1%
Q4 24
-184.2%
Q3 24
-360.5%
Q2 24
-17241.1%
Q1 24
-2932.9%
Q4 23
Q3 23
-868.1%
EPS (diluted)
MGTX
MGTX
PTHS
PTHS
Q3 25
$-0.62
$-5.30
Q2 25
$-0.48
Q4 24
$-0.49
Q3 24
$-0.55
Q2 24
$-0.76
Q1 24
$-0.32
Q4 23
Q3 23
$-0.74

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
MGTX
MGTX
PTHS
PTHS
Cash + ST InvestmentsLiquidity on hand
$14.8M
$14.2M
Total DebtLower is stronger
Stockholders' EquityBook value
$-40.6M
$58.3M
Total Assets
$189.5M
$126.4M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
MGTX
MGTX
PTHS
PTHS
Q3 25
$14.8M
$14.2M
Q2 25
$32.2M
Q4 24
$103.7M
Q3 24
$122.9M
Q2 24
$100.0M
Q1 24
$119.2M
Q4 23
$129.6M
Q3 23
$63.4M
Stockholders' Equity
MGTX
MGTX
PTHS
PTHS
Q3 25
$-40.6M
$58.3M
Q2 25
$3.0M
Q4 24
$67.8M
Q3 24
$95.7M
Q2 24
$80.0M
Q1 24
$121.7M
Q4 23
$138.2M
Q3 23
$91.9M
Total Assets
MGTX
MGTX
PTHS
PTHS
Q3 25
$189.5M
$126.4M
Q2 25
$198.7M
Q4 24
$269.8M
Q3 24
$299.5M
Q2 24
$266.7M
Q1 24
$309.2M
Q4 23
$326.7M
Q3 23
$267.2M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
MGTX
MGTX
PTHS
PTHS
Operating Cash FlowLast quarter
$-12.2M
$-15.3M
Free Cash FlowOCF − Capex
$-12.8M
FCF MarginFCF / Revenue
-3128.0%
Capex IntensityCapex / Revenue
148.8%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-108.3M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
MGTX
MGTX
PTHS
PTHS
Q3 25
$-12.2M
$-15.3M
Q2 25
$-43.9M
Q4 24
$-23.3M
Q3 24
$-25.0M
Q2 24
$-19.5M
Q1 24
$-36.7M
Q4 23
$-105.4M
Q3 23
$-24.4M
Free Cash Flow
MGTX
MGTX
PTHS
PTHS
Q3 25
$-12.8M
Q2 25
$-45.2M
Q4 24
$-24.5M
Q3 24
$-25.8M
Q2 24
$-20.8M
Q1 24
$-38.4M
Q4 23
$-125.5M
Q3 23
$-28.0M
FCF Margin
MGTX
MGTX
PTHS
PTHS
Q3 25
-3128.0%
Q2 25
-1224.1%
Q4 24
-114.5%
Q3 24
-236.0%
Q2 24
-7370.6%
Q1 24
-5512.1%
Q4 23
-6153.9%
Q3 23
-548.3%
Capex Intensity
MGTX
MGTX
PTHS
PTHS
Q3 25
148.8%
Q2 25
33.4%
Q4 24
5.7%
Q3 24
6.7%
Q2 24
471.3%
Q1 24
240.7%
Q4 23
988.9%
Q3 23
69.8%

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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