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Side-by-side financial comparison of MEDICAL PROPERTIES TRUST INC (MPW) and REPLIGEN CORP (RGEN). Click either name above to swap in a different company.

MEDICAL PROPERTIES TRUST INC is the larger business by last-quarter revenue ($270.3M vs $197.9M, roughly 1.4× REPLIGEN CORP). REPLIGEN CORP runs the higher net margin — 6.7% vs 6.5%, a 0.2% gap on every dollar of revenue. On growth, MEDICAL PROPERTIES TRUST INC posted the faster year-over-year revenue change (16.6% vs 13.6%). Over the past eight quarters, REPLIGEN CORP's revenue compounded faster (14.4% CAGR vs -0.2%).

Medical Properties Trust, Inc. (MPT) is an international real estate investment trust (REIT) based in Birmingham, Alabama that purchases and invests in healthcare facilities and for-profit healthcare holding companies, primarily in the United States and Europe. Their property acquisitions often come in the form of sale-leaseback agreements, in which the original property owner sells the property to MPT and becomes their tenant. MPT's tenants are generally subject to long-term triple net lease...

Repligen Corporation is a global life sciences company devoted to the development and commercialization of innovative bioprocessing technologies and systems that enable efficiencies in the process of manufacturing biological drugs.2025 The company is based in Waltham, Massachusetts,2014 and was incorporated in Delaware in 1981. A public company, Repligen is listed on the NASDAQ exchange under the symbol RGEN. As of 2025, Repligen employs over 1,900 employees globally and serves primarily biop...

MPW vs RGEN — Head-to-Head

Bigger by revenue
MPW
MPW
1.4× larger
MPW
$270.3M
$197.9M
RGEN
Growing faster (revenue YoY)
MPW
MPW
+3.0% gap
MPW
16.6%
13.6%
RGEN
Higher net margin
RGEN
RGEN
0.2% more per $
RGEN
6.7%
6.5%
MPW
Faster 2-yr revenue CAGR
RGEN
RGEN
Annualised
RGEN
14.4%
-0.2%
MPW

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
MPW
MPW
RGEN
RGEN
Revenue
$270.3M
$197.9M
Net Profit
$17.6M
$13.3M
Gross Margin
95.8%
52.5%
Operating Margin
9.7%
9.0%
Net Margin
6.5%
6.7%
Revenue YoY
16.6%
13.6%
Net Profit YoY
104.3%
143.9%
EPS (diluted)
$0.03
$0.24

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
MPW
MPW
RGEN
RGEN
Q4 25
$270.3M
$197.9M
Q3 25
$237.5M
$188.8M
Q2 25
$240.4M
$182.4M
Q1 25
$223.8M
$169.2M
Q4 24
$231.8M
$174.1M
Q3 24
$225.8M
$154.9M
Q2 24
$266.6M
$154.1M
Q1 24
$271.3M
$151.3M
Net Profit
MPW
MPW
RGEN
RGEN
Q4 25
$17.6M
$13.3M
Q3 25
$-77.7M
$14.9M
Q2 25
$-98.4M
$14.9M
Q1 25
$-118.3M
$5.8M
Q4 24
$-412.3M
$-30.3M
Q3 24
$-801.2M
$-654.0K
Q2 24
$-320.6M
$3.3M
Q1 24
$-875.6M
$2.1M
Gross Margin
MPW
MPW
RGEN
RGEN
Q4 25
95.8%
52.5%
Q3 25
53.2%
Q2 25
91.8%
50.0%
Q1 25
63.6%
53.6%
Q4 24
90.9%
26.1%
Q3 24
96.5%
50.0%
Q2 24
98.4%
49.8%
Q1 24
84.9%
49.5%
Operating Margin
MPW
MPW
RGEN
RGEN
Q4 25
9.7%
9.0%
Q3 25
-28.0%
8.9%
Q2 25
-36.7%
7.6%
Q1 25
-48.5%
3.9%
Q4 24
-173.7%
-17.7%
Q3 24
-350.7%
-5.1%
Q2 24
-114.5%
1.0%
Q1 24
-318.6%
1.3%
Net Margin
MPW
MPW
RGEN
RGEN
Q4 25
6.5%
6.7%
Q3 25
-32.7%
7.9%
Q2 25
-40.9%
8.2%
Q1 25
-52.8%
3.4%
Q4 24
-177.8%
-17.4%
Q3 24
-354.8%
-0.4%
Q2 24
-120.3%
2.2%
Q1 24
-322.7%
1.4%
EPS (diluted)
MPW
MPW
RGEN
RGEN
Q4 25
$0.03
$0.24
Q3 25
$-0.13
$0.26
Q2 25
$-0.16
$0.26
Q1 25
$-0.20
$0.10
Q4 24
$-0.68
$-0.55
Q3 24
$-1.34
$-0.01
Q2 24
$-0.54
$0.06
Q1 24
$-1.46
$0.04

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
MPW
MPW
RGEN
RGEN
Cash + ST InvestmentsLiquidity on hand
$540.9M
$767.6M
Total DebtLower is stronger
$9.7B
$542.2M
Stockholders' EquityBook value
$4.6B
$2.1B
Total Assets
$15.0B
$2.9B
Debt / EquityLower = less leverage
2.11×
0.26×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
MPW
MPW
RGEN
RGEN
Q4 25
$540.9M
$767.6M
Q3 25
$396.6M
$748.7M
Q2 25
$509.8M
$708.9M
Q1 25
$673.5M
$697.2M
Q4 24
$332.3M
$757.4M
Q3 24
$275.6M
$784.0M
Q2 24
$606.5M
$809.1M
Q1 24
$224.3M
$780.6M
Total Debt
MPW
MPW
RGEN
RGEN
Q4 25
$9.7B
$542.2M
Q3 25
$9.6B
$537.9M
Q2 25
$9.6B
Q1 25
$9.5B
Q4 24
$8.8B
$525.6M
Q3 24
$9.2B
Q2 24
$9.4B
Q1 24
$10.1B
Stockholders' Equity
MPW
MPW
RGEN
RGEN
Q4 25
$4.6B
$2.1B
Q3 25
$4.7B
$2.1B
Q2 25
$4.8B
$2.1B
Q1 25
$4.8B
$2.0B
Q4 24
$4.8B
$2.0B
Q3 24
$5.4B
$2.0B
Q2 24
$6.2B
$2.0B
Q1 24
$6.7B
$2.0B
Total Assets
MPW
MPW
RGEN
RGEN
Q4 25
$15.0B
$2.9B
Q3 25
$14.9B
$2.9B
Q2 25
$15.2B
$2.9B
Q1 25
$14.9B
$2.9B
Q4 24
$14.3B
$2.8B
Q3 24
$15.2B
$2.8B
Q2 24
$16.2B
$2.9B
Q1 24
$17.3B
$2.8B
Debt / Equity
MPW
MPW
RGEN
RGEN
Q4 25
2.11×
0.26×
Q3 25
2.06×
0.26×
Q2 25
2.00×
Q1 25
1.99×
Q4 24
1.83×
0.27×
Q3 24
1.69×
Q2 24
1.51×
Q1 24
1.51×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
MPW
MPW
RGEN
RGEN
Operating Cash FlowLast quarter
$230.8M
$25.7M
Free Cash FlowOCF − Capex
$17.6M
FCF MarginFCF / Revenue
8.9%
Capex IntensityCapex / Revenue
4.1%
Cash ConversionOCF / Net Profit
13.11×
1.93×
TTM Free Cash FlowTrailing 4 quarters
$93.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
MPW
MPW
RGEN
RGEN
Q4 25
$230.8M
$25.7M
Q3 25
$18.6M
$48.1M
Q2 25
$51.7M
$28.6M
Q1 25
$384.0K
$15.0M
Q4 24
$245.5M
$39.2M
Q3 24
$59.2M
$49.3M
Q2 24
$35.3M
$42.2M
Q1 24
$74.3M
$44.7M
Free Cash Flow
MPW
MPW
RGEN
RGEN
Q4 25
$17.6M
Q3 25
$43.4M
Q2 25
$21.5M
Q1 25
$11.4M
Q4 24
$33.6M
Q3 24
$42.3M
Q2 24
$37.4M
Q1 24
$36.4M
FCF Margin
MPW
MPW
RGEN
RGEN
Q4 25
8.9%
Q3 25
23.0%
Q2 25
11.8%
Q1 25
6.8%
Q4 24
19.3%
Q3 24
27.3%
Q2 24
24.3%
Q1 24
24.0%
Capex Intensity
MPW
MPW
RGEN
RGEN
Q4 25
4.1%
Q3 25
2.5%
Q2 25
3.9%
Q1 25
2.1%
Q4 24
3.2%
Q3 24
4.5%
Q2 24
3.1%
Q1 24
5.5%
Cash Conversion
MPW
MPW
RGEN
RGEN
Q4 25
13.11×
1.93×
Q3 25
3.23×
Q2 25
1.92×
Q1 25
2.57×
Q4 24
Q3 24
Q2 24
12.70×
Q1 24
21.35×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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