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Side-by-side financial comparison of Enpro Inc. (NPO) and PTC THERAPEUTICS, INC. (PTCT). Click either name above to swap in a different company.

Enpro Inc. is the larger business by last-quarter revenue ($295.4M vs $164.7M, roughly 1.8× PTC THERAPEUTICS, INC.). Enpro Inc. runs the higher net margin — -10.8% vs -82.0%, a 71.1% gap on every dollar of revenue. On growth, Enpro Inc. posted the faster year-over-year revenue change (14.3% vs -22.7%). Over the past eight quarters, Enpro Inc.'s revenue compounded faster (7.1% CAGR vs -11.5%).

Enpro is a US-based industrial technology company that designs and manufactures products and materials for technology-intensive sectors. The company serves industries such as semiconductors, aerospace, power generation, heavy-duty trucking, agricultural machinery, chemical processing, pulp and paper, and life sciences from 61 primary manufacturing facilities located in 12 countries, worldwide. It is organized under three segments: Sealing Technologies, Advanced Surface Technologies, and Engin...

PTC Therapeutics, Inc. is a US pharmaceutical company focused on the development of orally administered small molecule drugs and gene therapy which regulate gene expression by targeting post-transcriptional control (PTC) mechanisms in orphan diseases.

NPO vs PTCT — Head-to-Head

Bigger by revenue
NPO
NPO
1.8× larger
NPO
$295.4M
$164.7M
PTCT
Growing faster (revenue YoY)
NPO
NPO
+37.1% gap
NPO
14.3%
-22.7%
PTCT
Higher net margin
NPO
NPO
71.1% more per $
NPO
-10.8%
-82.0%
PTCT
Faster 2-yr revenue CAGR
NPO
NPO
Annualised
NPO
7.1%
-11.5%
PTCT

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
NPO
NPO
PTCT
PTCT
Revenue
$295.4M
$164.7M
Net Profit
$-32.0M
$-135.0M
Gross Margin
42.1%
Operating Margin
11.2%
-43.3%
Net Margin
-10.8%
-82.0%
Revenue YoY
14.3%
-22.7%
Net Profit YoY
-330.2%
-104.8%
EPS (diluted)
$-1.50
$-1.63

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
NPO
NPO
PTCT
PTCT
Q4 25
$295.4M
$164.7M
Q3 25
$286.6M
$211.0M
Q2 25
$288.1M
$178.9M
Q1 25
$273.2M
$1.2B
Q4 24
$258.4M
$213.2M
Q3 24
$260.9M
$196.8M
Q2 24
$271.9M
$186.7M
Q1 24
$257.5M
$210.1M
Net Profit
NPO
NPO
PTCT
PTCT
Q4 25
$-32.0M
$-135.0M
Q3 25
$21.6M
$15.9M
Q2 25
$26.4M
$-64.8M
Q1 25
$24.5M
$866.6M
Q4 24
$13.9M
$-65.9M
Q3 24
$19.8M
$-106.7M
Q2 24
$26.7M
$-99.2M
Q1 24
$12.5M
$-91.6M
Gross Margin
NPO
NPO
PTCT
PTCT
Q4 25
42.1%
Q3 25
41.9%
Q2 25
43.3%
Q1 25
43.3%
Q4 24
42.3%
Q3 24
42.3%
Q2 24
43.8%
Q1 24
41.2%
Operating Margin
NPO
NPO
PTCT
PTCT
Q4 25
11.2%
-43.3%
Q3 25
14.3%
1.4%
Q2 25
15.9%
-19.5%
Q1 25
15.3%
82.5%
Q4 24
12.5%
-76.2%
Q3 24
13.1%
-27.7%
Q2 24
17.7%
-21.5%
Q1 24
10.9%
-21.6%
Net Margin
NPO
NPO
PTCT
PTCT
Q4 25
-10.8%
-82.0%
Q3 25
7.5%
7.5%
Q2 25
9.2%
-36.3%
Q1 25
9.0%
73.7%
Q4 24
5.4%
-30.9%
Q3 24
7.6%
-54.2%
Q2 24
9.8%
-53.1%
Q1 24
4.9%
-43.6%
EPS (diluted)
NPO
NPO
PTCT
PTCT
Q4 25
$-1.50
$-1.63
Q3 25
$1.01
$0.20
Q2 25
$1.25
$-0.83
Q1 25
$1.15
$10.04
Q4 24
$0.65
$-0.85
Q3 24
$0.94
$-1.39
Q2 24
$1.27
$-1.29
Q1 24
$0.59
$-1.20

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
NPO
NPO
PTCT
PTCT
Cash + ST InvestmentsLiquidity on hand
$114.7M
$1.9B
Total DebtLower is stronger
$655.3M
Stockholders' EquityBook value
$1.5B
$-205.3M
Total Assets
$2.7B
$2.9B
Debt / EquityLower = less leverage
0.42×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
NPO
NPO
PTCT
PTCT
Q4 25
$114.7M
$1.9B
Q3 25
$132.9M
$1.7B
Q2 25
$107.1M
$2.0B
Q1 25
$240.3M
$2.0B
Q4 24
$236.3M
$1.1B
Q3 24
$206.9M
$1.0B
Q2 24
$175.9M
$1.1B
Q1 24
$163.9M
$884.8M
Total Debt
NPO
NPO
PTCT
PTCT
Q4 25
$655.3M
Q3 25
Q2 25
Q1 25
Q4 24
$640.1M
Q3 24
Q2 24
Q1 24
$644.9M
Stockholders' Equity
NPO
NPO
PTCT
PTCT
Q4 25
$1.5B
$-205.3M
Q3 25
$1.5B
$-155.8M
Q2 25
$1.5B
$-206.5M
Q1 25
$1.5B
$-185.8M
Q4 24
$1.4B
$-1.1B
Q3 24
$1.5B
$-1.1B
Q2 24
$1.4B
$-980.2M
Q1 24
$1.4B
$-893.9M
Total Assets
NPO
NPO
PTCT
PTCT
Q4 25
$2.7B
$2.9B
Q3 25
$2.4B
$2.6B
Q2 25
$2.4B
$2.6B
Q1 25
$2.5B
$2.7B
Q4 24
$2.5B
$1.7B
Q3 24
$2.5B
$1.8B
Q2 24
$2.5B
$1.9B
Q1 24
$2.5B
$1.8B
Debt / Equity
NPO
NPO
PTCT
PTCT
Q4 25
0.42×
Q3 25
Q2 25
Q1 25
Q4 24
0.45×
Q3 24
Q2 24
Q1 24
0.46×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
NPO
NPO
PTCT
PTCT
Operating Cash FlowLast quarter
$-34.3M
Free Cash FlowOCF − Capex
$-36.6M
FCF MarginFCF / Revenue
-22.3%
Capex IntensityCapex / Revenue
4.1%
1.4%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$702.3M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
NPO
NPO
PTCT
PTCT
Q4 25
$-34.3M
Q3 25
$65.3M
$-66.3M
Q2 25
$52.2M
$-58.3M
Q1 25
$21.0M
$870.1M
Q4 24
$59.4M
$-30.0M
Q3 24
$54.0M
$-77.0M
Q2 24
$43.2M
$-71.5M
Q1 24
$6.3M
$70.8M
Free Cash Flow
NPO
NPO
PTCT
PTCT
Q4 25
$-36.6M
Q3 25
$53.4M
$-69.7M
Q2 25
$42.3M
$-59.6M
Q1 25
$13.0M
$868.4M
Q4 24
$49.1M
$-33.8M
Q3 24
$48.3M
$-77.5M
Q2 24
$38.3M
$-78.8M
Q1 24
$-1.9M
$61.2M
FCF Margin
NPO
NPO
PTCT
PTCT
Q4 25
-22.3%
Q3 25
18.6%
-33.1%
Q2 25
14.7%
-33.3%
Q1 25
4.8%
73.8%
Q4 24
19.0%
-15.8%
Q3 24
18.5%
-39.4%
Q2 24
14.1%
-42.2%
Q1 24
-0.7%
29.1%
Capex Intensity
NPO
NPO
PTCT
PTCT
Q4 25
4.1%
1.4%
Q3 25
4.2%
1.6%
Q2 25
3.4%
0.7%
Q1 25
2.9%
0.1%
Q4 24
4.0%
1.8%
Q3 24
2.2%
0.3%
Q2 24
1.8%
4.0%
Q1 24
3.2%
4.6%
Cash Conversion
NPO
NPO
PTCT
PTCT
Q4 25
Q3 25
3.02×
-4.17×
Q2 25
1.98×
Q1 25
0.86×
1.00×
Q4 24
4.27×
Q3 24
2.73×
Q2 24
1.62×
Q1 24
0.50×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

NPO
NPO

Sealing Technologies Segment$187.0M63%
General Industrial$71.3M24%
Power Generation$19.9M7%
Oiland Gas Market$15.0M5%
Semiconductors$2.2M1%

PTCT
PTCT

Segment breakdown not available.

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