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Side-by-side financial comparison of Nurix Therapeutics, Inc. (NRIX) and USCB FINANCIAL HOLDINGS, INC. (USCB). Click either name above to swap in a different company.

USCB FINANCIAL HOLDINGS, INC. is the larger business by last-quarter revenue ($22.2M vs $13.6M, roughly 1.6× Nurix Therapeutics, Inc.). USCB FINANCIAL HOLDINGS, INC. runs the higher net margin — 6.1% vs -576.1%, a 582.3% gap on every dollar of revenue. On growth, USCB FINANCIAL HOLDINGS, INC. posted the faster year-over-year revenue change (14.7% vs 2.2%). USCB FINANCIAL HOLDINGS, INC. produced more free cash flow last quarter ($42.5M vs $-73.0M). Over the past eight quarters, USCB FINANCIAL HOLDINGS, INC.'s revenue compounded faster (12.3% CAGR vs -9.5%).

Nurix Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on discovering, developing and commercializing novel targeted protein degradation therapies for cancer, immune disorders and other serious unmet medical needs. Its core pipeline leverages proprietary E3 ubiquitin ligase modulation technology, with operations primarily based in the United States and collaborative partnerships with global pharmaceutical firms.

USCB Financial Holdings, Inc. is a U.S.-headquartered bank holding company that offers comprehensive retail and commercial banking services, including deposit products, personal and business loans, wealth management, and digital banking tools. It primarily serves individual consumers, small and medium-sized enterprises, and local corporate clients across its operating regions in the United States, prioritizing personalized customer experiences and community-oriented financial services.

NRIX vs USCB — Head-to-Head

Bigger by revenue
USCB
USCB
1.6× larger
USCB
$22.2M
$13.6M
NRIX
Growing faster (revenue YoY)
USCB
USCB
+12.5% gap
USCB
14.7%
2.2%
NRIX
Higher net margin
USCB
USCB
582.3% more per $
USCB
6.1%
-576.1%
NRIX
More free cash flow
USCB
USCB
$115.5M more FCF
USCB
$42.5M
$-73.0M
NRIX
Faster 2-yr revenue CAGR
USCB
USCB
Annualised
USCB
12.3%
-9.5%
NRIX

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
NRIX
NRIX
USCB
USCB
Revenue
$13.6M
$22.2M
Net Profit
$-78.2M
$1.4M
Gross Margin
Operating Margin
-612.0%
14.7%
Net Margin
-576.1%
6.1%
Revenue YoY
2.2%
14.7%
Net Profit YoY
-33.6%
-80.3%
EPS (diluted)
$-0.83

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
NRIX
NRIX
USCB
USCB
Q4 25
$13.6M
$22.2M
Q3 25
$7.9M
$25.0M
Q2 25
$44.1M
$24.4M
Q1 25
$18.5M
$22.8M
Q4 24
$13.3M
$23.0M
Q3 24
$12.6M
$21.5M
Q2 24
$12.1M
$20.5M
Q1 24
$16.6M
$17.6M
Net Profit
NRIX
NRIX
USCB
USCB
Q4 25
$-78.2M
$1.4M
Q3 25
$-86.4M
$8.9M
Q2 25
$-43.5M
$8.1M
Q1 25
$-56.4M
$7.7M
Q4 24
$-58.5M
$6.9M
Q3 24
$-49.0M
$6.9M
Q2 24
$-44.5M
$6.2M
Q1 24
$-41.5M
$4.6M
Operating Margin
NRIX
NRIX
USCB
USCB
Q4 25
-612.0%
14.7%
Q3 25
-1157.7%
47.3%
Q2 25
-109.7%
44.0%
Q1 25
-340.7%
44.2%
Q4 24
-486.7%
39.6%
Q3 24
-433.8%
42.5%
Q2 24
-401.4%
39.8%
Q1 24
-272.6%
34.3%
Net Margin
NRIX
NRIX
USCB
USCB
Q4 25
-576.1%
6.1%
Q3 25
-1094.8%
35.8%
Q2 25
-98.7%
33.4%
Q1 25
-305.4%
33.5%
Q4 24
-440.7%
30.0%
Q3 24
-388.9%
32.3%
Q2 24
-368.4%
30.3%
Q1 24
-250.3%
26.2%
EPS (diluted)
NRIX
NRIX
USCB
USCB
Q4 25
$-0.83
Q3 25
$-1.03
$0.45
Q2 25
$-0.52
Q1 25
$-0.67
Q4 24
$-0.74
Q3 24
$-0.67
$0.35
Q2 24
$-0.71
Q1 24
$-0.76

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
NRIX
NRIX
USCB
USCB
Cash + ST InvestmentsLiquidity on hand
$247.0M
$38.5M
Total DebtLower is stronger
Stockholders' EquityBook value
$538.7M
$217.2M
Total Assets
$688.1M
$2.8B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
NRIX
NRIX
USCB
USCB
Q4 25
$247.0M
$38.5M
Q3 25
$78.4M
$56.8M
Q2 25
$84.3M
$54.8M
Q1 25
$75.9M
$98.0M
Q4 24
$110.0M
$77.0M
Q3 24
$99.0M
$38.5M
Q2 24
$116.8M
$77.3M
Q1 24
$49.8M
$126.5M
Stockholders' Equity
NRIX
NRIX
USCB
USCB
Q4 25
$538.7M
$217.2M
Q3 25
$372.3M
$209.1M
Q2 25
$447.6M
$231.6M
Q1 25
$480.9M
$225.1M
Q4 24
$527.0M
$215.4M
Q3 24
$376.9M
$213.9M
Q2 24
$370.7M
$201.0M
Q1 24
$168.7M
$195.0M
Total Assets
NRIX
NRIX
USCB
USCB
Q4 25
$688.1M
$2.8B
Q3 25
$522.5M
$2.8B
Q2 25
$591.6M
$2.7B
Q1 25
$615.0M
$2.7B
Q4 24
$669.3M
$2.6B
Q3 24
$513.6M
$2.5B
Q2 24
$511.0M
$2.5B
Q1 24
$312.7M
$2.5B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
NRIX
NRIX
USCB
USCB
Operating Cash FlowLast quarter
$-67.8M
$42.8M
Free Cash FlowOCF − Capex
$-73.0M
$42.5M
FCF MarginFCF / Revenue
-537.4%
191.4%
Capex IntensityCapex / Revenue
37.8%
1.4%
Cash ConversionOCF / Net Profit
31.40×
TTM Free Cash FlowTrailing 4 quarters
$-263.5M
$95.1M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
NRIX
NRIX
USCB
USCB
Q4 25
$-67.8M
$42.8M
Q3 25
$-57.4M
$20.1M
Q2 25
$-63.2M
$18.0M
Q1 25
$-61.1M
$14.6M
Q4 24
$-48.8M
$34.8M
Q3 24
$-42.2M
$11.3M
Q2 24
$-39.7M
$18.3M
Q1 24
$-42.0M
$8.1M
Free Cash Flow
NRIX
NRIX
USCB
USCB
Q4 25
$-73.0M
$42.5M
Q3 25
$-60.1M
$20.0M
Q2 25
$-65.8M
$18.0M
Q1 25
$-64.6M
$14.6M
Q4 24
$-50.9M
$34.5M
Q3 24
$-44.5M
$11.2M
Q2 24
$-41.6M
$18.2M
Q1 24
$-44.8M
$8.0M
FCF Margin
NRIX
NRIX
USCB
USCB
Q4 25
-537.4%
191.4%
Q3 25
-761.3%
80.3%
Q2 25
-149.4%
73.7%
Q1 25
-349.9%
63.9%
Q4 24
-382.8%
150.2%
Q3 24
-353.7%
52.2%
Q2 24
-344.4%
88.8%
Q1 24
-270.3%
45.4%
Capex Intensity
NRIX
NRIX
USCB
USCB
Q4 25
37.8%
1.4%
Q3 25
34.3%
0.5%
Q2 25
6.1%
0.2%
Q1 25
18.9%
0.2%
Q4 24
15.8%
1.4%
Q3 24
18.6%
0.4%
Q2 24
16.0%
0.4%
Q1 24
17.4%
0.5%
Cash Conversion
NRIX
NRIX
USCB
USCB
Q4 25
31.40×
Q3 25
2.25×
Q2 25
2.22×
Q1 25
1.91×
Q4 24
5.05×
Q3 24
1.63×
Q2 24
2.95×
Q1 24
1.75×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

NRIX
NRIX

Pfizer$11.9M88%
Gilead Agreement$1.7M13%

USCB
USCB

Segment breakdown not available.

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