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Side-by-side financial comparison of Intellia Therapeutics, Inc. (NTLA) and Orchid Island Capital, Inc. (ORC). Click either name above to swap in a different company.

Orchid Island Capital, Inc. is the larger business by last-quarter revenue ($38.5M vs $23.0M, roughly 1.7× Intellia Therapeutics, Inc.). Orchid Island Capital, Inc. runs the higher net margin — 268.7% vs -416.2%, a 684.9% gap on every dollar of revenue. On growth, Orchid Island Capital, Inc. posted the faster year-over-year revenue change (372.6% vs 78.8%). Over the past eight quarters, Orchid Island Capital, Inc.'s revenue compounded faster (301.6% CAGR vs -10.8%).

Intellia Therapeutics, Inc. is an American clinical-stage biotechnology company focused on developing novel, potentially curative therapeutics leveraging CRISPR-based technologies. The company's in vivo programs use intravenously administered CRISPR as the therapy, in which the company's proprietary delivery technology enables highly precise editing of disease-causing genes directly within specific target tissues. Intellia's ex vivo programs use CRISPR to create the therapy by using engineere...

Orchid Island Capital, Inc. is a U.S.-based specialty finance company operating as a real estate investment trust. It primarily invests in residential mortgage-backed securities, including agency and non-agency products, targeting consistent risk-adjusted returns for its investors across U.S. fixed income markets.

NTLA vs ORC — Head-to-Head

Bigger by revenue
ORC
ORC
1.7× larger
ORC
$38.5M
$23.0M
NTLA
Growing faster (revenue YoY)
ORC
ORC
+293.8% gap
ORC
372.6%
78.8%
NTLA
Higher net margin
ORC
ORC
684.9% more per $
ORC
268.7%
-416.2%
NTLA
Faster 2-yr revenue CAGR
ORC
ORC
Annualised
ORC
301.6%
-10.8%
NTLA

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
NTLA
NTLA
ORC
ORC
Revenue
$23.0M
$38.5M
Net Profit
$-95.8M
$103.4M
Gross Margin
Operating Margin
-428.9%
Net Margin
-416.2%
268.7%
Revenue YoY
78.8%
372.6%
Net Profit YoY
25.7%
1764.9%
EPS (diluted)
$-0.81

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
NTLA
NTLA
ORC
ORC
Q4 25
$23.0M
$38.5M
Q3 25
$13.8M
$26.9M
Q2 25
$14.2M
$23.2M
Q1 25
$16.6M
$19.7M
Q4 24
$12.9M
Q3 24
$9.1M
$340.0K
Q2 24
$7.0M
$-697.0K
Q1 24
$28.9M
$-2.5M
Net Profit
NTLA
NTLA
ORC
ORC
Q4 25
$-95.8M
$103.4M
Q3 25
$-101.3M
$72.1M
Q2 25
$-101.3M
$-33.6M
Q1 25
$-114.3M
$17.1M
Q4 24
$-128.9M
Q3 24
$-135.7M
$17.3M
Q2 24
$-147.0M
$-5.0M
Q1 24
$-107.4M
$19.8M
Operating Margin
NTLA
NTLA
ORC
ORC
Q4 25
-428.9%
Q3 25
-808.9%
Q2 25
-772.2%
Q1 25
-726.6%
Q4 24
-1059.9%
Q3 24
-1589.0%
Q2 24
-1998.6%
Q1 24
-394.0%
Net Margin
NTLA
NTLA
ORC
ORC
Q4 25
-416.2%
268.7%
Q3 25
-735.2%
267.8%
Q2 25
-710.8%
-145.0%
Q1 25
-687.6%
86.9%
Q4 24
-1001.2%
Q3 24
-1489.5%
5094.1%
Q2 24
-2112.6%
714.3%
Q1 24
-371.3%
-794.2%
EPS (diluted)
NTLA
NTLA
ORC
ORC
Q4 25
$-0.81
Q3 25
$-0.92
Q2 25
$-0.98
Q1 25
$-1.10
Q4 24
$-1.27
Q3 24
$-1.34
Q2 24
$-1.52
Q1 24
$-1.12

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
NTLA
NTLA
ORC
ORC
Cash + ST InvestmentsLiquidity on hand
$449.9M
$665.9M
Total DebtLower is stronger
Stockholders' EquityBook value
$671.4M
$1.4B
Total Assets
$842.1M
$11.7B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
NTLA
NTLA
ORC
ORC
Q4 25
$449.9M
$665.9M
Q3 25
$511.0M
$583.9M
Q2 25
$459.7M
$440.8M
Q1 25
$503.7M
$396.4M
Q4 24
$601.5M
Q3 24
$658.1M
$322.1M
Q2 24
$691.1M
$241.0M
Q1 24
$791.3M
$190.4M
Stockholders' Equity
NTLA
NTLA
ORC
ORC
Q4 25
$671.4M
$1.4B
Q3 25
$748.4M
$1.1B
Q2 25
$715.3M
$912.0M
Q1 25
$779.9M
$855.9M
Q4 24
$872.0M
Q3 24
$962.6M
$656.0M
Q2 24
$971.1M
$555.9M
Q1 24
$1.0B
$481.6M
Total Assets
NTLA
NTLA
ORC
ORC
Q4 25
$842.1M
$11.7B
Q3 25
$925.3M
$9.1B
Q2 25
$898.9M
$7.6B
Q1 25
$986.2M
$7.3B
Q4 24
$1.2B
Q3 24
$1.2B
$5.9B
Q2 24
$1.2B
$4.9B
Q1 24
$1.3B
$4.2B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
NTLA
NTLA
ORC
ORC
Operating Cash FlowLast quarter
$-69.3M
$120.4M
Free Cash FlowOCF − Capex
$-69.4M
FCF MarginFCF / Revenue
-301.6%
Capex IntensityCapex / Revenue
0.5%
Cash ConversionOCF / Net Profit
1.16×
TTM Free Cash FlowTrailing 4 quarters
$-395.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
NTLA
NTLA
ORC
ORC
Q4 25
$-69.3M
$120.4M
Q3 25
$-76.9M
$28.0M
Q2 25
$-99.6M
$18.4M
Q1 25
$-148.9M
$25.8M
Q4 24
$-85.2M
Q3 24
$-84.8M
$-14.8M
Q2 24
$-58.2M
$19.3M
Q1 24
$-120.7M
$45.0M
Free Cash Flow
NTLA
NTLA
ORC
ORC
Q4 25
$-69.4M
Q3 25
$-76.9M
Q2 25
$-99.9M
Q1 25
$-149.7M
Q4 24
$-86.2M
Q3 24
$-86.1M
Q2 24
$-59.2M
Q1 24
$-123.2M
FCF Margin
NTLA
NTLA
ORC
ORC
Q4 25
-301.6%
Q3 25
-558.2%
Q2 25
-701.0%
Q1 25
-900.1%
Q4 24
-669.4%
Q3 24
-945.2%
Q2 24
-850.9%
Q1 24
-425.7%
Capex Intensity
NTLA
NTLA
ORC
ORC
Q4 25
0.5%
Q3 25
0.2%
Q2 25
1.7%
Q1 25
4.4%
Q4 24
7.6%
Q3 24
14.0%
Q2 24
14.5%
Q1 24
8.7%
Cash Conversion
NTLA
NTLA
ORC
ORC
Q4 25
1.16×
Q3 25
0.39×
Q2 25
Q1 25
1.51×
Q4 24
Q3 24
-0.86×
Q2 24
Q1 24
2.28×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

NTLA
NTLA

Avencell Therapeutics Inc$21.0M91%
Other$1.0M4%
Avencell$1.0M4%

ORC
ORC

Segment breakdown not available.

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