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Side-by-side financial comparison of Ocugen, Inc. (OCGN) and PROTHENA CORP PUBLIC LTD CO (PRTA). Click either name above to swap in a different company.

On growth, PROTHENA CORP PUBLIC LTD CO posted the faster year-over-year revenue change (-99.0% vs -125.3%). Over the past eight quarters, PROTHENA CORP PUBLIC LTD CO's revenue compounded faster (NaN% CAGR vs NaN%).

Ocugen, Inc. is a clinical-stage biopharmaceutical company focused on developing innovative therapies for ophthalmic diseases, including rare inherited retinal disorders and age-related eye conditions. It operates primarily in the North American market, with a pipeline covering gene therapies, biologics, and vaccine candidates targeting unmet medical needs.

Prothena Corporation plc is a late-stage clinical biotechnology firm focused on developing and commercializing innovative antibody therapies for neurodegenerative disorders, rare diseases and immune-related conditions. Its core pipeline targets unmet medical needs including amyloidosis, Parkinson's and Alzheimer's, serving key markets across North America, Europe and the Asia-Pacific.

OCGN vs PRTA — Head-to-Head

Bigger by revenue
PRTA
PRTA
-0.1× larger
PRTA
$21.0K
$-193.0K
OCGN
Growing faster (revenue YoY)
PRTA
PRTA
+26.3% gap
PRTA
-99.0%
-125.3%
OCGN
Faster 2-yr revenue CAGR
PRTA
PRTA
Annualised
PRTA
-35.2%
NaN%
OCGN

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
OCGN
OCGN
PRTA
PRTA
Revenue
$-193.0K
$21.0K
Net Profit
Gross Margin
Operating Margin
8805.7%
Net Margin
Revenue YoY
-125.3%
-99.0%
Net Profit YoY
62.7%
EPS (diluted)

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
OCGN
OCGN
PRTA
PRTA
Q4 25
$-193.0K
$21.0K
Q3 25
$1.8M
$2.4M
Q2 25
$1.4M
$4.4M
Q1 25
$1.5M
$2.8M
Q4 24
$764.0K
$2.1M
Q3 24
$1.1M
$970.0K
Q2 24
$1.1M
$132.0M
Q1 24
$1.0M
$50.0K
Net Profit
OCGN
OCGN
PRTA
PRTA
Q4 25
Q3 25
$-20.1M
$-36.5M
Q2 25
$-14.7M
$-125.8M
Q1 25
$-15.3M
$-60.2M
Q4 24
Q3 24
$-13.0M
$-59.0M
Q2 24
$-15.3M
$66.9M
Q1 24
$-11.9M
$-72.2M
Operating Margin
OCGN
OCGN
PRTA
PRTA
Q4 25
8805.7%
Q3 25
-1006.0%
-1666.3%
Q2 25
-1004.7%
-1914.4%
Q1 25
-979.1%
-2319.0%
Q4 24
-1811.5%
Q3 24
-1166.5%
-6857.0%
Q2 24
-1354.0%
44.2%
Q1 24
-1204.7%
-163056.0%
Net Margin
OCGN
OCGN
PRTA
PRTA
Q4 25
Q3 25
-1144.5%
-1513.1%
Q2 25
-1073.5%
-2845.4%
Q1 25
-1036.5%
-2128.5%
Q4 24
Q3 24
-1141.7%
-6082.6%
Q2 24
-1339.2%
50.7%
Q1 24
-1175.9%
-144478.0%
EPS (diluted)
OCGN
OCGN
PRTA
PRTA
Q4 25
Q3 25
$-0.68
Q2 25
$-2.34
Q1 25
$-1.12
Q4 24
Q3 24
$-1.10
Q2 24
$-0.04
$1.22
Q1 24
$-0.05
$-1.34

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
OCGN
OCGN
PRTA
PRTA
Cash + ST InvestmentsLiquidity on hand
$307.5M
Total DebtLower is stronger
Stockholders' EquityBook value
$-12.2M
$280.5M
Total Assets
$43.5M
$326.8M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
OCGN
OCGN
PRTA
PRTA
Q4 25
$307.5M
Q3 25
$330.8M
Q2 25
$371.4M
Q1 25
$37.8M
$417.9M
Q4 24
$471.4M
Q3 24
$519.3M
Q2 24
$15.7M
$564.1M
Q1 24
$26.4M
$546.5M
Stockholders' Equity
OCGN
OCGN
PRTA
PRTA
Q4 25
$-12.2M
$280.5M
Q3 25
$3.5M
$295.0M
Q2 25
$3.1M
$324.3M
Q1 25
$15.9M
$437.7M
Q4 24
$29.6M
$486.9M
Q3 24
$40.6M
$534.4M
Q2 24
$16.9M
$581.9M
Q1 24
$30.3M
$502.4M
Total Assets
OCGN
OCGN
PRTA
PRTA
Q4 25
$43.5M
$326.8M
Q3 25
$57.6M
$352.6M
Q2 25
$53.6M
$399.1M
Q1 25
$64.5M
$495.3M
Q4 24
$82.4M
$547.1M
Q3 24
$61.9M
$595.3M
Q2 24
$40.5M
$645.6M
Q1 24
$51.8M
$623.2M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
OCGN
OCGN
PRTA
PRTA
Operating Cash FlowLast quarter
$-14.0M
$-163.6M
Free Cash FlowOCF − Capex
$-14.0M
FCF MarginFCF / Revenue
7251.8%
Capex IntensityCapex / Revenue
-18.1%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-57.1M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
OCGN
OCGN
PRTA
PRTA
Q4 25
$-14.0M
$-163.6M
Q3 25
$-12.9M
$-40.6M
Q2 25
$-10.7M
$-46.3M
Q1 25
$-19.4M
$-53.4M
Q4 24
$-10.4M
$-150.1M
Q3 24
$-11.3M
$-45.2M
Q2 24
$-9.9M
$16.0M
Q1 24
$-10.6M
$-73.1M
Free Cash Flow
OCGN
OCGN
PRTA
PRTA
Q4 25
$-14.0M
Q3 25
$-13.0M
Q2 25
$-10.8M
Q1 25
$-19.4M
Q4 24
$-10.4M
Q3 24
$-11.8M
Q2 24
$-10.4M
Q1 24
$-12.9M
FCF Margin
OCGN
OCGN
PRTA
PRTA
Q4 25
7251.8%
Q3 25
-742.4%
Q2 25
-784.6%
Q1 25
-1308.1%
Q4 24
-1358.2%
Q3 24
-1036.9%
Q2 24
-913.6%
Q1 24
-1276.8%
Capex Intensity
OCGN
OCGN
PRTA
PRTA
Q4 25
-18.1%
Q3 25
5.2%
Q2 25
3.1%
Q1 25
1.1%
Q4 24
1.7%
Q3 24
44.6%
Q2 24
45.0%
Q1 24
232.0%
Cash Conversion
OCGN
OCGN
PRTA
PRTA
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
0.24×
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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