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Side-by-side financial comparison of OPKO HEALTH, INC. (OPK) and Ranpak Holdings Corp. (PACK). Click either name above to swap in a different company.

OPKO HEALTH, INC. is the larger business by last-quarter revenue ($148.5M vs $93.7M, roughly 1.6× Ranpak Holdings Corp.). On growth, Ranpak Holdings Corp. posted the faster year-over-year revenue change (2.3% vs -19.2%). Over the past eight quarters, Ranpak Holdings Corp.'s revenue compounded faster (13.7% CAGR vs -7.5%).

OPKO Health, Inc. is a medical test and medication company focused on diagnostics and pharmaceuticals. The company is a publicly traded company on NASDAQ and TASE under the symbol "OPK".

Ranpak Holdings Corp. manufactures machines and paper products used in protective paper-based packing for shipping goods and merchandise for e-commerce and industry, along with automation solutions. The company is based in Concord, Ohio, and has production facilities and offices in Reno, Nevada; Kansas City, Missouri; the Netherlands; Czech Republic; Shanghai and Singapore. The paper packaging material can be used for multiple applications like wrapping, cushioning, void fill and cold chain p...

OPK vs PACK — Head-to-Head

Bigger by revenue
OPK
OPK
1.6× larger
OPK
$148.5M
$93.7M
PACK
Growing faster (revenue YoY)
PACK
PACK
+21.5% gap
PACK
2.3%
-19.2%
OPK
Faster 2-yr revenue CAGR
PACK
PACK
Annualised
PACK
13.7%
-7.5%
OPK

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
OPK
OPK
PACK
PACK
Revenue
$148.5M
$93.7M
Net Profit
$-31.3M
Gross Margin
43.1%
39.0%
Operating Margin
-25.8%
-1.0%
Net Margin
-21.1%
Revenue YoY
-19.2%
2.3%
Net Profit YoY
-322.8%
EPS (diluted)
$-0.04
$-0.11

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
OPK
OPK
PACK
PACK
Q4 25
$148.5M
$93.7M
Q3 25
$151.7M
$83.6M
Q2 25
$156.8M
$77.8M
Q1 25
$150.0M
$77.6M
Q4 24
$183.6M
$91.6M
Q3 24
$173.6M
$78.6M
Q2 24
$182.2M
$72.8M
Q1 24
$173.7M
$72.5M
Net Profit
OPK
OPK
PACK
PACK
Q4 25
$-31.3M
Q3 25
$21.6M
$-10.4M
Q2 25
$-148.4M
$-7.5M
Q1 25
$-67.6M
$-10.9M
Q4 24
$14.0M
Q3 24
$24.9M
$-8.1M
Q2 24
$-10.3M
$5.5M
Q1 24
$-81.8M
$-8.1M
Gross Margin
OPK
OPK
PACK
PACK
Q4 25
43.1%
39.0%
Q3 25
32.9%
41.1%
Q2 25
31.5%
37.1%
Q1 25
28.4%
39.8%
Q4 24
46.1%
45.2%
Q3 24
23.1%
43.8%
Q2 24
28.4%
43.5%
Q1 24
24.2%
44.6%
Operating Margin
OPK
OPK
PACK
PACK
Q4 25
-25.8%
-1.0%
Q3 25
31.7%
-6.8%
Q2 25
-38.3%
-12.5%
Q1 25
-44.8%
-10.3%
Q4 24
-18.0%
1.5%
Q3 24
8.2%
-5.3%
Q2 24
-33.9%
-7.1%
Q1 24
-41.2%
-6.6%
Net Margin
OPK
OPK
PACK
PACK
Q4 25
-21.1%
Q3 25
14.3%
-12.4%
Q2 25
-94.7%
-9.6%
Q1 25
-45.1%
-14.0%
Q4 24
7.6%
Q3 24
14.3%
-10.3%
Q2 24
-5.7%
7.6%
Q1 24
-47.1%
-11.2%
EPS (diluted)
OPK
OPK
PACK
PACK
Q4 25
$-0.04
$-0.11
Q3 25
$0.03
$-0.12
Q2 25
$-0.19
$-0.09
Q1 25
$-0.10
$-0.13
Q4 24
$0.02
$-0.13
Q3 24
$0.03
$-0.10
Q2 24
$-0.01
$0.07
Q1 24
$-0.12
$-0.10

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
OPK
OPK
PACK
PACK
Cash + ST InvestmentsLiquidity on hand
$364.4M
$63.0M
Total DebtLower is stronger
$344.0M
$401.9M
Stockholders' EquityBook value
$1.3B
$534.9M
Total Assets
$1.9B
$1.1B
Debt / EquityLower = less leverage
0.27×
0.75×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
OPK
OPK
PACK
PACK
Q4 25
$364.4M
$63.0M
Q3 25
$412.0M
$49.9M
Q2 25
$267.3M
$49.2M
Q1 25
$428.8M
$65.5M
Q4 24
$426.6M
$76.1M
Q3 24
$400.1M
$69.5M
Q2 24
$40.6M
$65.1M
Q1 24
$75.6M
$55.1M
Total Debt
OPK
OPK
PACK
PACK
Q4 25
$344.0M
$401.9M
Q3 25
$344.2M
$403.1M
Q2 25
$343.3M
$403.1M
Q1 25
$439.2M
$405.2M
Q4 24
$437.2M
$406.4M
Q3 24
$441.0M
$403.2M
Q2 24
$201.9M
$396.1M
Q1 24
$350.1M
$396.7M
Stockholders' Equity
OPK
OPK
PACK
PACK
Q4 25
$1.3B
$534.9M
Q3 25
$1.3B
$537.8M
Q2 25
$1.3B
$539.0M
Q1 25
$1.3B
$544.1M
Q4 24
$1.4B
$548.1M
Q3 24
$1.4B
$564.3M
Q2 24
$1.4B
$566.2M
Q1 24
$1.3B
$560.0M
Total Assets
OPK
OPK
PACK
PACK
Q4 25
$1.9B
$1.1B
Q3 25
$2.0B
$1.1B
Q2 25
$2.0B
$1.1B
Q1 25
$2.1B
$1.1B
Q4 24
$2.2B
$1.1B
Q3 24
$2.3B
$1.1B
Q2 24
$2.0B
$1.1B
Q1 24
$2.0B
$1.1B
Debt / Equity
OPK
OPK
PACK
PACK
Q4 25
0.27×
0.75×
Q3 25
0.26×
0.75×
Q2 25
0.26×
0.75×
Q1 25
0.33×
0.74×
Q4 24
0.32×
0.74×
Q3 24
0.31×
0.71×
Q2 24
0.14×
0.70×
Q1 24
0.28×
0.71×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
OPK
OPK
PACK
PACK
Operating Cash FlowLast quarter
$-25.9M
$19.5M
Free Cash FlowOCF − Capex
$-28.6M
FCF MarginFCF / Revenue
-19.3%
Capex IntensityCapex / Revenue
1.8%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-190.8M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
OPK
OPK
PACK
PACK
Q4 25
$-25.9M
$19.5M
Q3 25
$-34.6M
$8.5M
Q2 25
$-83.4M
$-3.6M
Q1 25
$-34.6M
$-1.3M
Q4 24
$-44.4M
$6.5M
Q3 24
$-77.1M
$10.1M
Q2 24
$-26.4M
$19.6M
Q1 24
$-35.6M
$5.2M
Free Cash Flow
OPK
OPK
PACK
PACK
Q4 25
$-28.6M
Q3 25
$-37.8M
Q2 25
$-86.7M
Q1 25
$-37.7M
Q4 24
$-49.8M
Q3 24
$-85.0M
Q2 24
$-33.7M
Q1 24
$-40.0M
FCF Margin
OPK
OPK
PACK
PACK
Q4 25
-19.3%
Q3 25
-24.9%
Q2 25
-55.3%
Q1 25
-25.2%
Q4 24
-27.1%
Q3 24
-49.0%
Q2 24
-18.5%
Q1 24
-23.0%
Capex Intensity
OPK
OPK
PACK
PACK
Q4 25
1.8%
Q3 25
2.1%
Q2 25
2.1%
Q1 25
2.1%
Q4 24
2.9%
Q3 24
4.6%
Q2 24
4.0%
Q1 24
2.6%
Cash Conversion
OPK
OPK
PACK
PACK
Q4 25
Q3 25
-1.60×
Q2 25
Q1 25
Q4 24
-3.17×
Q3 24
-3.10×
Q2 24
3.56×
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

OPK
OPK

Services$71.1M48%
Transfer Of Intellectual Property And Other$33.7M23%
IE$22.1M15%
Rayaldee$8.8M6%
Barda Agreement$6.8M5%
MX$6.3M4%

PACK
PACK

Other$47.9M51%
Europe And Asia Segment$45.8M49%

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