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Side-by-side financial comparison of OPKO HEALTH, INC. (OPK) and PennyMac Mortgage Investment Trust (PMT). Click either name above to swap in a different company.

OPKO HEALTH, INC. is the larger business by last-quarter revenue ($148.5M vs $93.6M, roughly 1.6× PennyMac Mortgage Investment Trust). PennyMac Mortgage Investment Trust runs the higher net margin — 56.0% vs -21.1%, a 77.0% gap on every dollar of revenue. On growth, PennyMac Mortgage Investment Trust posted the faster year-over-year revenue change (-13.3% vs -19.2%). Over the past eight quarters, PennyMac Mortgage Investment Trust's revenue compounded faster (12.3% CAGR vs -7.5%).

OPKO Health, Inc. is a medical test and medication company focused on diagnostics and pharmaceuticals. The company is a publicly traded company on NASDAQ and TASE under the symbol "OPK".

PennyMac Mortgage Investment Trust is a U.S.-headquartered real estate investment trust specializing in residential mortgage assets. It invests in performing and non-performing mortgage loans, mortgage-backed securities, and credit risk transfer instruments, operating across investment management and mortgage servicing segments in the U.S. housing market.

OPK vs PMT — Head-to-Head

Bigger by revenue
OPK
OPK
1.6× larger
OPK
$148.5M
$93.6M
PMT
Growing faster (revenue YoY)
PMT
PMT
+5.9% gap
PMT
-13.3%
-19.2%
OPK
Higher net margin
PMT
PMT
77.0% more per $
PMT
56.0%
-21.1%
OPK
Faster 2-yr revenue CAGR
PMT
PMT
Annualised
PMT
12.3%
-7.5%
OPK

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
OPK
OPK
PMT
PMT
Revenue
$148.5M
$93.6M
Net Profit
$-31.3M
$52.4M
Gross Margin
43.1%
Operating Margin
-25.8%
38.6%
Net Margin
-21.1%
56.0%
Revenue YoY
-19.2%
-13.3%
Net Profit YoY
-322.8%
12.5%
EPS (diluted)
$-0.04
$0.49

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
OPK
OPK
PMT
PMT
Q4 25
$148.5M
$93.6M
Q3 25
$151.7M
$99.2M
Q2 25
$156.8M
$70.2M
Q1 25
$150.0M
$44.5M
Q4 24
$183.6M
$107.9M
Q3 24
$173.6M
$80.9M
Q2 24
$182.2M
$71.2M
Q1 24
$173.7M
$74.2M
Net Profit
OPK
OPK
PMT
PMT
Q4 25
$-31.3M
$52.4M
Q3 25
$21.6M
$58.3M
Q2 25
$-148.4M
$7.5M
Q1 25
$-67.6M
$9.7M
Q4 24
$14.0M
$46.5M
Q3 24
$24.9M
$41.4M
Q2 24
$-10.3M
$25.4M
Q1 24
$-81.8M
$47.6M
Gross Margin
OPK
OPK
PMT
PMT
Q4 25
43.1%
Q3 25
32.9%
Q2 25
31.5%
Q1 25
28.4%
Q4 24
46.1%
Q3 24
23.1%
Q2 24
28.4%
Q1 24
24.2%
Operating Margin
OPK
OPK
PMT
PMT
Q4 25
-25.8%
38.6%
Q3 25
31.7%
47.4%
Q2 25
-38.3%
24.2%
Q1 25
-44.8%
-14.2%
Q4 24
-18.0%
51.1%
Q3 24
8.2%
32.8%
Q2 24
-33.9%
40.2%
Q1 24
-41.2%
43.6%
Net Margin
OPK
OPK
PMT
PMT
Q4 25
-21.1%
56.0%
Q3 25
14.3%
58.7%
Q2 25
-94.7%
10.7%
Q1 25
-45.1%
21.8%
Q4 24
7.6%
43.1%
Q3 24
14.3%
51.2%
Q2 24
-5.7%
35.7%
Q1 24
-47.1%
64.2%
EPS (diluted)
OPK
OPK
PMT
PMT
Q4 25
$-0.04
$0.49
Q3 25
$0.03
$0.55
Q2 25
$-0.19
$-0.04
Q1 25
$-0.10
$-0.01
Q4 24
$0.02
$0.45
Q3 24
$0.03
$0.36
Q2 24
$-0.01
$0.17
Q1 24
$-0.12
$0.39

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
OPK
OPK
PMT
PMT
Cash + ST InvestmentsLiquidity on hand
$364.4M
$190.5M
Total DebtLower is stronger
$344.0M
$1.1B
Stockholders' EquityBook value
$1.3B
$1.9B
Total Assets
$1.9B
$21.3B
Debt / EquityLower = less leverage
0.27×
0.58×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
OPK
OPK
PMT
PMT
Q4 25
$364.4M
$190.5M
Q3 25
$412.0M
$181.0M
Q2 25
$267.3M
$108.6M
Q1 25
$428.8M
$204.2M
Q4 24
$426.6M
$103.2M
Q3 24
$400.1M
$102.8M
Q2 24
$40.6M
$336.3M
Q1 24
$75.6M
$343.3M
Total Debt
OPK
OPK
PMT
PMT
Q4 25
$344.0M
$1.1B
Q3 25
$344.2M
$299.0M
Q2 25
$343.3M
$1.2B
Q1 25
$439.2M
$968.4M
Q4 24
$437.2M
$1.0B
Q3 24
$441.0M
$5.2B
Q2 24
$201.9M
$5.4B
Q1 24
$350.1M
$5.1B
Stockholders' Equity
OPK
OPK
PMT
PMT
Q4 25
$1.3B
$1.9B
Q3 25
$1.3B
$1.9B
Q2 25
$1.3B
$1.9B
Q1 25
$1.3B
$1.9B
Q4 24
$1.4B
$1.9B
Q3 24
$1.4B
$1.9B
Q2 24
$1.4B
$1.9B
Q1 24
$1.3B
$2.0B
Total Assets
OPK
OPK
PMT
PMT
Q4 25
$1.9B
$21.3B
Q3 25
$2.0B
$18.5B
Q2 25
$2.0B
$16.8B
Q1 25
$2.1B
$14.9B
Q4 24
$2.2B
$14.4B
Q3 24
$2.3B
$13.1B
Q2 24
$2.0B
$12.1B
Q1 24
$2.0B
$12.3B
Debt / Equity
OPK
OPK
PMT
PMT
Q4 25
0.27×
0.58×
Q3 25
0.26×
0.16×
Q2 25
0.26×
0.65×
Q1 25
0.33×
0.51×
Q4 24
0.32×
0.52×
Q3 24
0.31×
2.70×
Q2 24
0.14×
2.76×
Q1 24
0.28×
2.60×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
OPK
OPK
PMT
PMT
Operating Cash FlowLast quarter
$-25.9M
$-7.2B
Free Cash FlowOCF − Capex
$-28.6M
FCF MarginFCF / Revenue
-19.3%
Capex IntensityCapex / Revenue
1.8%
Cash ConversionOCF / Net Profit
-137.76×
TTM Free Cash FlowTrailing 4 quarters
$-190.8M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
OPK
OPK
PMT
PMT
Q4 25
$-25.9M
$-7.2B
Q3 25
$-34.6M
$-1.3B
Q2 25
$-83.4M
$-2.0B
Q1 25
$-34.6M
$-594.3M
Q4 24
$-44.4M
$-2.7B
Q3 24
$-77.1M
$-983.8M
Q2 24
$-26.4M
$243.8M
Q1 24
$-35.6M
$-342.4M
Free Cash Flow
OPK
OPK
PMT
PMT
Q4 25
$-28.6M
Q3 25
$-37.8M
Q2 25
$-86.7M
Q1 25
$-37.7M
Q4 24
$-49.8M
Q3 24
$-85.0M
Q2 24
$-33.7M
Q1 24
$-40.0M
FCF Margin
OPK
OPK
PMT
PMT
Q4 25
-19.3%
Q3 25
-24.9%
Q2 25
-55.3%
Q1 25
-25.2%
Q4 24
-27.1%
Q3 24
-49.0%
Q2 24
-18.5%
Q1 24
-23.0%
Capex Intensity
OPK
OPK
PMT
PMT
Q4 25
1.8%
Q3 25
2.1%
Q2 25
2.1%
Q1 25
2.1%
Q4 24
2.9%
Q3 24
4.6%
Q2 24
4.0%
Q1 24
2.6%
Cash Conversion
OPK
OPK
PMT
PMT
Q4 25
-137.76×
Q3 25
-1.60×
-22.26×
Q2 25
-267.53×
Q1 25
-61.39×
Q4 24
-3.17×
-58.08×
Q3 24
-3.10×
-23.76×
Q2 24
9.59×
Q1 24
-7.19×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

OPK
OPK

Services$71.1M48%
Transfer Of Intellectual Property And Other$33.7M23%
IE$22.1M15%
Rayaldee$8.8M6%
Barda Agreement$6.8M5%
MX$6.3M4%

PMT
PMT

Other$55.0M59%
Interest Rate Sensitive Strategies$31.4M34%
Correspondent Production$7.2M8%

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