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Side-by-side financial comparison of OPKO HEALTH, INC. (OPK) and POWER INTEGRATIONS INC (POWI). Click either name above to swap in a different company.

OPKO HEALTH, INC. is the larger business by last-quarter revenue ($148.5M vs $103.2M, roughly 1.4× POWER INTEGRATIONS INC). POWER INTEGRATIONS INC runs the higher net margin — 12.9% vs -21.1%, a 33.9% gap on every dollar of revenue. On growth, POWER INTEGRATIONS INC posted the faster year-over-year revenue change (-1.9% vs -19.2%). POWER INTEGRATIONS INC produced more free cash flow last quarter ($19.2M vs $-28.6M). Over the past eight quarters, POWER INTEGRATIONS INC's revenue compounded faster (6.1% CAGR vs -7.5%).

OPKO Health, Inc. is a medical test and medication company focused on diagnostics and pharmaceuticals. The company is a publicly traded company on NASDAQ and TASE under the symbol "OPK".

American Electric Power Company, Inc. is an American domestic electric utility company in the United States. It is one of the largest electric utility companies in the country, with more than five million customers in 11 states.

OPK vs POWI — Head-to-Head

Bigger by revenue
OPK
OPK
1.4× larger
OPK
$148.5M
$103.2M
POWI
Growing faster (revenue YoY)
POWI
POWI
+17.2% gap
POWI
-1.9%
-19.2%
OPK
Higher net margin
POWI
POWI
33.9% more per $
POWI
12.9%
-21.1%
OPK
More free cash flow
POWI
POWI
$47.7M more FCF
POWI
$19.2M
$-28.6M
OPK
Faster 2-yr revenue CAGR
POWI
POWI
Annualised
POWI
6.1%
-7.5%
OPK

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
OPK
OPK
POWI
POWI
Revenue
$148.5M
$103.2M
Net Profit
$-31.3M
$13.3M
Gross Margin
43.1%
52.9%
Operating Margin
-25.8%
8.5%
Net Margin
-21.1%
12.9%
Revenue YoY
-19.2%
-1.9%
Net Profit YoY
-322.8%
45.4%
EPS (diluted)
$-0.04
$0.24

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
OPK
OPK
POWI
POWI
Q4 25
$148.5M
$103.2M
Q3 25
$151.7M
$118.9M
Q2 25
$156.8M
$115.9M
Q1 25
$150.0M
$105.5M
Q4 24
$183.6M
$105.3M
Q3 24
$173.6M
$115.8M
Q2 24
$182.2M
$106.2M
Q1 24
$173.7M
$91.7M
Net Profit
OPK
OPK
POWI
POWI
Q4 25
$-31.3M
$13.3M
Q3 25
$21.6M
$-1.4M
Q2 25
$-148.4M
$1.4M
Q1 25
$-67.6M
$8.8M
Q4 24
$14.0M
$9.1M
Q3 24
$24.9M
$14.3M
Q2 24
$-10.3M
$4.8M
Q1 24
$-81.8M
$4.0M
Gross Margin
OPK
OPK
POWI
POWI
Q4 25
43.1%
52.9%
Q3 25
32.9%
54.5%
Q2 25
31.5%
55.2%
Q1 25
28.4%
55.2%
Q4 24
46.1%
54.4%
Q3 24
23.1%
54.5%
Q2 24
28.4%
53.2%
Q1 24
24.2%
52.1%
Operating Margin
OPK
OPK
POWI
POWI
Q4 25
-25.8%
8.5%
Q3 25
31.7%
-3.3%
Q2 25
-38.3%
-1.2%
Q1 25
-44.8%
6.4%
Q4 24
-18.0%
3.7%
Q3 24
8.2%
10.0%
Q2 24
-33.9%
1.8%
Q1 24
-41.2%
0.5%
Net Margin
OPK
OPK
POWI
POWI
Q4 25
-21.1%
12.9%
Q3 25
14.3%
-1.1%
Q2 25
-94.7%
1.2%
Q1 25
-45.1%
8.3%
Q4 24
7.6%
8.7%
Q3 24
14.3%
12.3%
Q2 24
-5.7%
4.6%
Q1 24
-47.1%
4.3%
EPS (diluted)
OPK
OPK
POWI
POWI
Q4 25
$-0.04
$0.24
Q3 25
$0.03
$-0.02
Q2 25
$-0.19
$0.02
Q1 25
$-0.10
$0.15
Q4 24
$0.02
$0.15
Q3 24
$0.03
$0.25
Q2 24
$-0.01
$0.09
Q1 24
$-0.12
$0.07

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
OPK
OPK
POWI
POWI
Cash + ST InvestmentsLiquidity on hand
$364.4M
$249.5M
Total DebtLower is stronger
$344.0M
Stockholders' EquityBook value
$1.3B
$672.8M
Total Assets
$1.9B
$772.2M
Debt / EquityLower = less leverage
0.27×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
OPK
OPK
POWI
POWI
Q4 25
$364.4M
$249.5M
Q3 25
$412.0M
$241.9M
Q2 25
$267.3M
$268.7M
Q1 25
$428.8M
$289.3M
Q4 24
$426.6M
$300.0M
Q3 24
$400.1M
$303.8M
Q2 24
$40.6M
$290.5M
Q1 24
$75.6M
$299.6M
Total Debt
OPK
OPK
POWI
POWI
Q4 25
$344.0M
Q3 25
$344.2M
Q2 25
$343.3M
Q1 25
$439.2M
Q4 24
$437.2M
Q3 24
$441.0M
Q2 24
$201.9M
Q1 24
$350.1M
Stockholders' Equity
OPK
OPK
POWI
POWI
Q4 25
$1.3B
$672.8M
Q3 25
$1.3B
$672.0M
Q2 25
$1.3B
$703.8M
Q1 25
$1.3B
$735.8M
Q4 24
$1.4B
$749.8M
Q3 24
$1.4B
$749.2M
Q2 24
$1.4B
$730.7M
Q1 24
$1.3B
$738.2M
Total Assets
OPK
OPK
POWI
POWI
Q4 25
$1.9B
$772.2M
Q3 25
$2.0B
$772.5M
Q2 25
$2.0B
$797.5M
Q1 25
$2.1B
$814.4M
Q4 24
$2.2B
$828.8M
Q3 24
$2.3B
$825.0M
Q2 24
$2.0B
$804.8M
Q1 24
$2.0B
$805.8M
Debt / Equity
OPK
OPK
POWI
POWI
Q4 25
0.27×
Q3 25
0.26×
Q2 25
0.26×
Q1 25
0.33×
Q4 24
0.32×
Q3 24
0.31×
Q2 24
0.14×
Q1 24
0.28×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
OPK
OPK
POWI
POWI
Operating Cash FlowLast quarter
$-25.9M
$26.2M
Free Cash FlowOCF − Capex
$-28.6M
$19.2M
FCF MarginFCF / Revenue
-19.3%
18.6%
Capex IntensityCapex / Revenue
1.8%
6.8%
Cash ConversionOCF / Net Profit
1.97×
TTM Free Cash FlowTrailing 4 quarters
$-190.8M
$87.1M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
OPK
OPK
POWI
POWI
Q4 25
$-25.9M
$26.2M
Q3 25
$-34.6M
$29.9M
Q2 25
$-83.4M
$29.1M
Q1 25
$-34.6M
$26.4M
Q4 24
$-44.4M
$14.7M
Q3 24
$-77.1M
$32.9M
Q2 24
$-26.4M
$17.6M
Q1 24
$-35.6M
$15.9M
Free Cash Flow
OPK
OPK
POWI
POWI
Q4 25
$-28.6M
$19.2M
Q3 25
$-37.8M
$24.2M
Q2 25
$-86.7M
$23.1M
Q1 25
$-37.7M
$20.7M
Q4 24
$-49.8M
$11.7M
Q3 24
$-85.0M
$27.2M
Q2 24
$-33.7M
$13.5M
Q1 24
$-40.0M
$11.6M
FCF Margin
OPK
OPK
POWI
POWI
Q4 25
-19.3%
18.6%
Q3 25
-24.9%
20.3%
Q2 25
-55.3%
20.0%
Q1 25
-25.2%
19.6%
Q4 24
-27.1%
11.1%
Q3 24
-49.0%
23.5%
Q2 24
-18.5%
12.7%
Q1 24
-23.0%
12.6%
Capex Intensity
OPK
OPK
POWI
POWI
Q4 25
1.8%
6.8%
Q3 25
2.1%
4.8%
Q2 25
2.1%
5.1%
Q1 25
2.1%
5.4%
Q4 24
2.9%
2.9%
Q3 24
4.6%
4.9%
Q2 24
4.0%
3.9%
Q1 24
2.6%
4.7%
Cash Conversion
OPK
OPK
POWI
POWI
Q4 25
1.97×
Q3 25
-1.60×
Q2 25
21.24×
Q1 25
3.00×
Q4 24
-3.17×
1.61×
Q3 24
-3.10×
2.30×
Q2 24
3.64×
Q1 24
4.02×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

OPK
OPK

Services$71.1M48%
Transfer Of Intellectual Property And Other$33.7M23%
IE$22.1M15%
Rayaldee$8.8M6%
Barda Agreement$6.8M5%
MX$6.3M4%

POWI
POWI

Distributors$65.8M64%
Other$10.3M10%
KR$9.3M9%
DE$7.1M7%
TW$5.5M5%
Emea Other Than Germany$5.3M5%

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