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Side-by-side financial comparison of OPKO HEALTH, INC. (OPK) and PROGRESS SOFTWARE CORP (PRGS). Click either name above to swap in a different company.

PROGRESS SOFTWARE CORP is the larger business by last-quarter revenue ($252.7M vs $148.5M, roughly 1.7× OPKO HEALTH, INC.). PROGRESS SOFTWARE CORP runs the higher net margin — 10.2% vs -21.1%, a 31.2% gap on every dollar of revenue. On growth, PROGRESS SOFTWARE CORP posted the faster year-over-year revenue change (17.5% vs -19.2%). PROGRESS SOFTWARE CORP produced more free cash flow last quarter ($59.9M vs $-28.6M). Over the past eight quarters, PROGRESS SOFTWARE CORP's revenue compounded faster (17.0% CAGR vs -7.5%).

OPKO Health, Inc. is a medical test and medication company focused on diagnostics and pharmaceuticals. The company is a publicly traded company on NASDAQ and TASE under the symbol "OPK".

Progress Software Corporation develops and sells enterprise software products including application development platforms, data connectivity tools, and digital experience solutions. It serves global enterprise clients across finance, healthcare, manufacturing, retail and other sectors, helping organizations build scalable, high-performance business applications and streamline operational workflows.

OPK vs PRGS — Head-to-Head

Bigger by revenue
PRGS
PRGS
1.7× larger
PRGS
$252.7M
$148.5M
OPK
Growing faster (revenue YoY)
PRGS
PRGS
+36.7% gap
PRGS
17.5%
-19.2%
OPK
Higher net margin
PRGS
PRGS
31.2% more per $
PRGS
10.2%
-21.1%
OPK
More free cash flow
PRGS
PRGS
$88.5M more FCF
PRGS
$59.9M
$-28.6M
OPK
Faster 2-yr revenue CAGR
PRGS
PRGS
Annualised
PRGS
17.0%
-7.5%
OPK

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
OPK
OPK
PRGS
PRGS
Revenue
$148.5M
$252.7M
Net Profit
$-31.3M
$25.7M
Gross Margin
43.1%
81.6%
Operating Margin
-25.8%
15.2%
Net Margin
-21.1%
10.2%
Revenue YoY
-19.2%
17.5%
Net Profit YoY
-322.8%
2144.6%
EPS (diluted)
$-0.04
$0.59

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
OPK
OPK
PRGS
PRGS
Q4 25
$148.5M
$252.7M
Q3 25
$151.7M
$249.8M
Q2 25
$156.8M
$237.4M
Q1 25
$150.0M
$238.0M
Q4 24
$183.6M
$215.0M
Q3 24
$173.6M
$178.7M
Q2 24
$182.2M
$175.1M
Q1 24
$173.7M
$184.7M
Net Profit
OPK
OPK
PRGS
PRGS
Q4 25
$-31.3M
$25.7M
Q3 25
$21.6M
$19.4M
Q2 25
$-148.4M
$17.0M
Q1 25
$-67.6M
$10.9M
Q4 24
$14.0M
$1.1M
Q3 24
$24.9M
$28.5M
Q2 24
$-10.3M
$16.2M
Q1 24
$-81.8M
$22.6M
Gross Margin
OPK
OPK
PRGS
PRGS
Q4 25
43.1%
81.6%
Q3 25
32.9%
81.0%
Q2 25
31.5%
80.1%
Q1 25
28.4%
80.6%
Q4 24
46.1%
83.0%
Q3 24
23.1%
83.7%
Q2 24
28.4%
81.7%
Q1 24
24.2%
82.2%
Operating Margin
OPK
OPK
PRGS
PRGS
Q4 25
-25.8%
15.2%
Q3 25
31.7%
17.6%
Q2 25
-38.3%
16.3%
Q1 25
-44.8%
13.6%
Q4 24
-18.0%
10.0%
Q3 24
8.2%
22.6%
Q2 24
-33.9%
15.5%
Q1 24
-41.2%
19.0%
Net Margin
OPK
OPK
PRGS
PRGS
Q4 25
-21.1%
10.2%
Q3 25
14.3%
7.8%
Q2 25
-94.7%
7.2%
Q1 25
-45.1%
4.6%
Q4 24
7.6%
0.5%
Q3 24
14.3%
15.9%
Q2 24
-5.7%
9.2%
Q1 24
-47.1%
12.3%
EPS (diluted)
OPK
OPK
PRGS
PRGS
Q4 25
$-0.04
$0.59
Q3 25
$0.03
$0.44
Q2 25
$-0.19
$0.39
Q1 25
$-0.10
$0.24
Q4 24
$0.02
$0.01
Q3 24
$0.03
$0.65
Q2 24
$-0.01
$0.37
Q1 24
$-0.12
$0.51

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
OPK
OPK
PRGS
PRGS
Cash + ST InvestmentsLiquidity on hand
$364.4M
$94.8M
Total DebtLower is stronger
$344.0M
$1.4B
Stockholders' EquityBook value
$1.3B
$478.3M
Total Assets
$1.9B
$2.5B
Debt / EquityLower = less leverage
0.27×
2.93×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
OPK
OPK
PRGS
PRGS
Q4 25
$364.4M
$94.8M
Q3 25
$412.0M
$99.0M
Q2 25
$267.3M
$102.0M
Q1 25
$428.8M
$124.2M
Q4 24
$426.6M
$118.1M
Q3 24
$400.1M
$232.7M
Q2 24
$40.6M
$190.4M
Q1 24
$75.6M
$133.2M
Total Debt
OPK
OPK
PRGS
PRGS
Q4 25
$344.0M
$1.4B
Q3 25
$344.2M
$1.4B
Q2 25
$343.3M
$1.5B
Q1 25
$439.2M
$1.5B
Q4 24
$437.2M
$1.5B
Q3 24
$441.0M
Q2 24
$201.9M
Q1 24
$350.1M
Stockholders' Equity
OPK
OPK
PRGS
PRGS
Q4 25
$1.3B
$478.3M
Q3 25
$1.3B
$477.7M
Q2 25
$1.3B
$452.7M
Q1 25
$1.3B
$431.8M
Q4 24
$1.4B
$438.8M
Q3 24
$1.4B
$425.6M
Q2 24
$1.4B
$401.7M
Q1 24
$1.3B
$461.7M
Total Assets
OPK
OPK
PRGS
PRGS
Q4 25
$1.9B
$2.5B
Q3 25
$2.0B
$2.4B
Q2 25
$2.0B
$2.4B
Q1 25
$2.1B
$2.5B
Q4 24
$2.2B
$2.5B
Q3 24
$2.3B
$1.6B
Q2 24
$2.0B
$1.6B
Q1 24
$2.0B
$1.5B
Debt / Equity
OPK
OPK
PRGS
PRGS
Q4 25
0.27×
2.93×
Q3 25
0.26×
2.97×
Q2 25
0.26×
3.22×
Q1 25
0.33×
3.50×
Q4 24
0.32×
3.48×
Q3 24
0.31×
Q2 24
0.14×
Q1 24
0.28×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
OPK
OPK
PRGS
PRGS
Operating Cash FlowLast quarter
$-25.9M
$62.8M
Free Cash FlowOCF − Capex
$-28.6M
$59.9M
FCF MarginFCF / Revenue
-19.3%
23.7%
Capex IntensityCapex / Revenue
1.8%
1.1%
Cash ConversionOCF / Net Profit
2.44×
TTM Free Cash FlowTrailing 4 quarters
$-190.8M
$229.5M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
OPK
OPK
PRGS
PRGS
Q4 25
$-25.9M
$62.8M
Q3 25
$-34.6M
$73.4M
Q2 25
$-83.4M
$30.0M
Q1 25
$-34.6M
$68.9M
Q4 24
$-44.4M
$19.7M
Q3 24
$-77.1M
$57.7M
Q2 24
$-26.4M
$63.7M
Q1 24
$-35.6M
$70.5M
Free Cash Flow
OPK
OPK
PRGS
PRGS
Q4 25
$-28.6M
$59.9M
Q3 25
$-37.8M
$72.4M
Q2 25
$-86.7M
$29.5M
Q1 25
$-37.7M
$67.7M
Q4 24
$-49.8M
$16.8M
Q3 24
$-85.0M
$56.6M
Q2 24
$-33.7M
$62.7M
Q1 24
$-40.0M
$70.2M
FCF Margin
OPK
OPK
PRGS
PRGS
Q4 25
-19.3%
23.7%
Q3 25
-24.9%
29.0%
Q2 25
-55.3%
12.4%
Q1 25
-25.2%
28.4%
Q4 24
-27.1%
7.8%
Q3 24
-49.0%
31.7%
Q2 24
-18.5%
35.8%
Q1 24
-23.0%
38.0%
Capex Intensity
OPK
OPK
PRGS
PRGS
Q4 25
1.8%
1.1%
Q3 25
2.1%
0.4%
Q2 25
2.1%
0.2%
Q1 25
2.1%
0.5%
Q4 24
2.9%
1.3%
Q3 24
4.6%
0.6%
Q2 24
4.0%
0.5%
Q1 24
2.6%
0.2%
Cash Conversion
OPK
OPK
PRGS
PRGS
Q4 25
2.44×
Q3 25
-1.60×
3.78×
Q2 25
1.76×
Q1 25
6.30×
Q4 24
-3.17×
17.13×
Q3 24
-3.10×
2.03×
Q2 24
3.93×
Q1 24
3.11×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

OPK
OPK

Services$71.1M48%
Transfer Of Intellectual Property And Other$33.7M23%
IE$22.1M15%
Rayaldee$8.8M6%
Barda Agreement$6.8M5%
MX$6.3M4%

PRGS
PRGS

Maintenanceand Services$187.5M74%
Share File Acquisition$67.5M27%

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