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Side-by-side financial comparison of OPKO HEALTH, INC. (OPK) and Riley Exploration Permian, Inc. (REPX). Click either name above to swap in a different company.

OPKO HEALTH, INC. is the larger business by last-quarter revenue ($148.5M vs $97.3M, roughly 1.5× Riley Exploration Permian, Inc.). On growth, Riley Exploration Permian, Inc. posted the faster year-over-year revenue change (-5.3% vs -19.2%). Over the past eight quarters, Riley Exploration Permian, Inc.'s revenue compounded faster (-1.2% CAGR vs -7.5%).

OPKO Health, Inc. is a medical test and medication company focused on diagnostics and pharmaceuticals. The company is a publicly traded company on NASDAQ and TASE under the symbol "OPK".

Riley Exploration Permian, Inc. is an independent energy company focused on exploration, development, and production of crude oil, natural gas, and natural gas liquids primarily in the US Permian Basin spanning Texas and New Mexico. It prioritizes cost-efficient onshore reserve development to supply reliable energy products to North American markets.

OPK vs REPX — Head-to-Head

Bigger by revenue
OPK
OPK
1.5× larger
OPK
$148.5M
$97.3M
REPX
Growing faster (revenue YoY)
REPX
REPX
+13.9% gap
REPX
-5.3%
-19.2%
OPK
Faster 2-yr revenue CAGR
REPX
REPX
Annualised
REPX
-1.2%
-7.5%
OPK

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
OPK
OPK
REPX
REPX
Revenue
$148.5M
$97.3M
Net Profit
$-31.3M
Gross Margin
43.1%
Operating Margin
-25.8%
26.9%
Net Margin
-21.1%
Revenue YoY
-19.2%
-5.3%
Net Profit YoY
-322.8%
EPS (diluted)
$-0.04
$4.02

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
OPK
OPK
REPX
REPX
Q4 25
$148.5M
$97.3M
Q3 25
$151.7M
$106.9M
Q2 25
$156.8M
$85.4M
Q1 25
$150.0M
$102.5M
Q4 24
$183.6M
$102.7M
Q3 24
$173.6M
$102.3M
Q2 24
$182.2M
$105.4M
Q1 24
$173.7M
$99.7M
Net Profit
OPK
OPK
REPX
REPX
Q4 25
$-31.3M
Q3 25
$21.6M
$16.3M
Q2 25
$-148.4M
$30.5M
Q1 25
$-67.6M
$28.6M
Q4 24
$14.0M
Q3 24
$24.9M
$25.7M
Q2 24
$-10.3M
$33.5M
Q1 24
$-81.8M
$18.8M
Gross Margin
OPK
OPK
REPX
REPX
Q4 25
43.1%
Q3 25
32.9%
Q2 25
31.5%
Q1 25
28.4%
Q4 24
46.1%
Q3 24
23.1%
Q2 24
28.4%
Q1 24
24.2%
Operating Margin
OPK
OPK
REPX
REPX
Q4 25
-25.8%
26.9%
Q3 25
31.7%
27.0%
Q2 25
-38.3%
33.7%
Q1 25
-44.8%
48.3%
Q4 24
-18.0%
31.2%
Q3 24
8.2%
17.1%
Q2 24
-33.9%
50.9%
Q1 24
-41.2%
50.7%
Net Margin
OPK
OPK
REPX
REPX
Q4 25
-21.1%
Q3 25
14.3%
15.3%
Q2 25
-94.7%
35.7%
Q1 25
-45.1%
27.9%
Q4 24
7.6%
Q3 24
14.3%
25.1%
Q2 24
-5.7%
31.8%
Q1 24
-47.1%
18.8%
EPS (diluted)
OPK
OPK
REPX
REPX
Q4 25
$-0.04
$4.02
Q3 25
$0.03
$0.77
Q2 25
$-0.19
$1.44
Q1 25
$-0.10
$1.36
Q4 24
$0.02
$0.52
Q3 24
$0.03
$1.21
Q2 24
$-0.01
$1.59
Q1 24
$-0.12
$0.94

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
OPK
OPK
REPX
REPX
Cash + ST InvestmentsLiquidity on hand
$364.4M
Total DebtLower is stronger
$344.0M
$247.9M
Stockholders' EquityBook value
$1.3B
$634.2M
Total Assets
$1.9B
$1.2B
Debt / EquityLower = less leverage
0.27×
0.39×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
OPK
OPK
REPX
REPX
Q4 25
$364.4M
Q3 25
$412.0M
Q2 25
$267.3M
Q1 25
$428.8M
Q4 24
$426.6M
Q3 24
$400.1M
Q2 24
$40.6M
Q1 24
$75.6M
Total Debt
OPK
OPK
REPX
REPX
Q4 25
$344.0M
$247.9M
Q3 25
$344.2M
$367.0M
Q2 25
$343.3M
$275.2M
Q1 25
$439.2M
$249.3M
Q4 24
$437.2M
$269.5M
Q3 24
$441.0M
$288.6M
Q2 24
$201.9M
$322.7M
Q1 24
$350.1M
$341.8M
Stockholders' Equity
OPK
OPK
REPX
REPX
Q4 25
$1.3B
$634.2M
Q3 25
$1.3B
$566.5M
Q2 25
$1.3B
$556.9M
Q1 25
$1.3B
$532.4M
Q4 24
$1.4B
$510.6M
Q3 24
$1.4B
$507.4M
Q2 24
$1.4B
$489.0M
Q1 24
$1.3B
$434.6M
Total Assets
OPK
OPK
REPX
REPX
Q4 25
$1.9B
$1.2B
Q3 25
$2.0B
$1.2B
Q2 25
$2.0B
$1.0B
Q1 25
$2.1B
$994.9M
Q4 24
$2.2B
$993.5M
Q3 24
$2.3B
$997.9M
Q2 24
$2.0B
$1.0B
Q1 24
$2.0B
$956.4M
Debt / Equity
OPK
OPK
REPX
REPX
Q4 25
0.27×
0.39×
Q3 25
0.26×
0.65×
Q2 25
0.26×
0.49×
Q1 25
0.33×
0.47×
Q4 24
0.32×
0.53×
Q3 24
0.31×
0.57×
Q2 24
0.14×
0.66×
Q1 24
0.28×
0.79×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
OPK
OPK
REPX
REPX
Operating Cash FlowLast quarter
$-25.9M
$64.9M
Free Cash FlowOCF − Capex
$-28.6M
FCF MarginFCF / Revenue
-19.3%
Capex IntensityCapex / Revenue
1.8%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-190.8M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
OPK
OPK
REPX
REPX
Q4 25
$-25.9M
$64.9M
Q3 25
$-34.6M
$63.6M
Q2 25
$-83.4M
$33.6M
Q1 25
$-34.6M
$50.4M
Q4 24
$-44.4M
$66.4M
Q3 24
$-77.1M
$72.1M
Q2 24
$-26.4M
$51.6M
Q1 24
$-35.6M
$56.1M
Free Cash Flow
OPK
OPK
REPX
REPX
Q4 25
$-28.6M
Q3 25
$-37.8M
Q2 25
$-86.7M
Q1 25
$-37.7M
Q4 24
$-49.8M
Q3 24
$-85.0M
Q2 24
$-33.7M
Q1 24
$-40.0M
FCF Margin
OPK
OPK
REPX
REPX
Q4 25
-19.3%
Q3 25
-24.9%
Q2 25
-55.3%
Q1 25
-25.2%
Q4 24
-27.1%
Q3 24
-49.0%
Q2 24
-18.5%
Q1 24
-23.0%
Capex Intensity
OPK
OPK
REPX
REPX
Q4 25
1.8%
Q3 25
2.1%
Q2 25
2.1%
Q1 25
2.1%
Q4 24
2.9%
Q3 24
4.6%
Q2 24
4.0%
Q1 24
2.6%
Cash Conversion
OPK
OPK
REPX
REPX
Q4 25
Q3 25
-1.60×
3.90×
Q2 25
1.10×
Q1 25
1.76×
Q4 24
-3.17×
Q3 24
-3.10×
2.81×
Q2 24
1.54×
Q1 24
2.99×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

OPK
OPK

Services$71.1M48%
Transfer Of Intellectual Property And Other$33.7M23%
IE$22.1M15%
Rayaldee$8.8M6%
Barda Agreement$6.8M5%
MX$6.3M4%

REPX
REPX

Segment breakdown not available.

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