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Side-by-side financial comparison of OPKO HEALTH, INC. (OPK) and Riot Platforms, Inc. (RIOT). Click either name above to swap in a different company.

Riot Platforms, Inc. is the larger business by last-quarter revenue ($152.8M vs $148.5M, roughly 1.0× OPKO HEALTH, INC.). OPKO HEALTH, INC. runs the higher net margin — -21.1% vs -452.0%, a 430.9% gap on every dollar of revenue. On growth, Riot Platforms, Inc. posted the faster year-over-year revenue change (7.2% vs -19.2%). OPKO HEALTH, INC. produced more free cash flow last quarter ($-28.6M vs $-774.3M). Over the past eight quarters, Riot Platforms, Inc.'s revenue compounded faster (38.8% CAGR vs -7.5%).

OPKO Health, Inc. is a medical test and medication company focused on diagnostics and pharmaceuticals. The company is a publicly traded company on NASDAQ and TASE under the symbol "OPK".

Riot Platforms, Inc. is a leading U.S.-based enterprise focused on Bitcoin mining, operating multiple large-scale, energy-efficient data centers across North America. It also invests in blockchain infrastructure development and holds Bitcoin as a core long-term reserve asset, centering its business strategy around the digital asset ecosystem.

OPK vs RIOT — Head-to-Head

Bigger by revenue
RIOT
RIOT
1.0× larger
RIOT
$152.8M
$148.5M
OPK
Growing faster (revenue YoY)
RIOT
RIOT
+26.4% gap
RIOT
7.2%
-19.2%
OPK
Higher net margin
OPK
OPK
430.9% more per $
OPK
-21.1%
-452.0%
RIOT
More free cash flow
OPK
OPK
$745.7M more FCF
OPK
$-28.6M
$-774.3M
RIOT
Faster 2-yr revenue CAGR
RIOT
RIOT
Annualised
RIOT
38.8%
-7.5%
OPK

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
OPK
OPK
RIOT
RIOT
Revenue
$148.5M
$152.8M
Net Profit
$-31.3M
$-690.7M
Gross Margin
43.1%
Operating Margin
-25.8%
-447.9%
Net Margin
-21.1%
-452.0%
Revenue YoY
-19.2%
7.2%
Net Profit YoY
-322.8%
-606.3%
EPS (diluted)
$-0.04
$-1.89

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
OPK
OPK
RIOT
RIOT
Q4 25
$148.5M
$152.8M
Q3 25
$151.7M
$180.2M
Q2 25
$156.8M
$153.0M
Q1 25
$150.0M
$161.4M
Q4 24
$183.6M
$142.6M
Q3 24
$173.6M
$84.8M
Q2 24
$182.2M
$70.0M
Q1 24
$173.7M
$79.3M
Net Profit
OPK
OPK
RIOT
RIOT
Q4 25
$-31.3M
$-690.7M
Q3 25
$21.6M
$104.5M
Q2 25
$-148.4M
$219.5M
Q1 25
$-67.6M
$-296.4M
Q4 24
$14.0M
$136.4M
Q3 24
$24.9M
$-154.4M
Q2 24
$-10.3M
$-84.4M
Q1 24
$-81.8M
$211.8M
Gross Margin
OPK
OPK
RIOT
RIOT
Q4 25
43.1%
Q3 25
32.9%
Q2 25
31.5%
Q1 25
28.4%
Q4 24
46.1%
Q3 24
23.1%
Q2 24
28.4%
Q1 24
24.2%
Operating Margin
OPK
OPK
RIOT
RIOT
Q4 25
-25.8%
-447.9%
Q3 25
31.7%
44.4%
Q2 25
-38.3%
Q1 25
-44.8%
-144.9%
Q4 24
-18.0%
Q3 24
8.2%
-143.3%
Q2 24
-33.9%
-167.2%
Q1 24
-41.2%
Net Margin
OPK
OPK
RIOT
RIOT
Q4 25
-21.1%
-452.0%
Q3 25
14.3%
58.0%
Q2 25
-94.7%
143.4%
Q1 25
-45.1%
-183.6%
Q4 24
7.6%
95.7%
Q3 24
14.3%
-182.1%
Q2 24
-5.7%
-120.6%
Q1 24
-47.1%
267.1%
EPS (diluted)
OPK
OPK
RIOT
RIOT
Q4 25
$-0.04
$-1.89
Q3 25
$0.03
$0.26
Q2 25
$-0.19
$0.58
Q1 25
$-0.10
$-0.90
Q4 24
$0.02
$0.39
Q3 24
$0.03
$-0.54
Q2 24
$-0.01
$-0.32
Q1 24
$-0.12
$0.51

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
OPK
OPK
RIOT
RIOT
Cash + ST InvestmentsLiquidity on hand
$364.4M
$233.5M
Total DebtLower is stronger
$344.0M
$840.8M
Stockholders' EquityBook value
$1.3B
$2.9B
Total Assets
$1.9B
$3.9B
Debt / EquityLower = less leverage
0.27×
0.29×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
OPK
OPK
RIOT
RIOT
Q4 25
$364.4M
$233.5M
Q3 25
$412.0M
$330.7M
Q2 25
$267.3M
$255.4M
Q1 25
$428.8M
$163.7M
Q4 24
$426.6M
$277.9M
Q3 24
$400.1M
$355.7M
Q2 24
$40.6M
$481.2M
Q1 24
$75.6M
$688.5M
Total Debt
OPK
OPK
RIOT
RIOT
Q4 25
$344.0M
$840.8M
Q3 25
$344.2M
$5.3M
Q2 25
$343.3M
$5.3M
Q1 25
$439.2M
$5.3M
Q4 24
$437.2M
$584.6M
Q3 24
$441.0M
$5.7M
Q2 24
$201.9M
Q1 24
$350.1M
Stockholders' Equity
OPK
OPK
RIOT
RIOT
Q4 25
$1.3B
$2.9B
Q3 25
$1.3B
$3.5B
Q2 25
$1.3B
$3.3B
Q1 25
$1.3B
$2.9B
Q4 24
$1.4B
$3.1B
Q3 24
$1.4B
$2.7B
Q2 24
$1.4B
$2.6B
Q1 24
$1.3B
$2.5B
Total Assets
OPK
OPK
RIOT
RIOT
Q4 25
$1.9B
$3.9B
Q3 25
$2.0B
$4.5B
Q2 25
$2.0B
$4.3B
Q1 25
$2.1B
$3.7B
Q4 24
$2.2B
$3.9B
Q3 24
$2.3B
$2.9B
Q2 24
$2.0B
$2.7B
Q1 24
$2.0B
$2.6B
Debt / Equity
OPK
OPK
RIOT
RIOT
Q4 25
0.27×
0.29×
Q3 25
0.26×
0.00×
Q2 25
0.26×
0.00×
Q1 25
0.33×
0.00×
Q4 24
0.32×
0.19×
Q3 24
0.31×
0.00×
Q2 24
0.14×
Q1 24
0.28×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
OPK
OPK
RIOT
RIOT
Operating Cash FlowLast quarter
$-25.9M
$-572.9M
Free Cash FlowOCF − Capex
$-28.6M
$-774.3M
FCF MarginFCF / Revenue
-19.3%
-506.6%
Capex IntensityCapex / Revenue
1.8%
131.8%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-190.8M
$-1.4B

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
OPK
OPK
RIOT
RIOT
Q4 25
$-25.9M
$-572.9M
Q3 25
$-34.6M
$-114.0M
Q2 25
$-83.4M
$-231.3M
Q1 25
$-34.6M
$-122.1M
Q4 24
$-44.4M
$-255.1M
Q3 24
$-77.1M
$-56.3M
Q2 24
$-26.4M
$-42.5M
Q1 24
$-35.6M
$-57.9M
Free Cash Flow
OPK
OPK
RIOT
RIOT
Q4 25
$-28.6M
$-774.3M
Q3 25
$-37.8M
$-139.7M
Q2 25
$-86.7M
$-291.7M
Q1 25
$-37.7M
$-154.9M
Q4 24
$-49.8M
$-495.4M
Q3 24
$-85.0M
$-127.6M
Q2 24
$-33.7M
$-96.1M
Q1 24
$-40.0M
$-115.2M
FCF Margin
OPK
OPK
RIOT
RIOT
Q4 25
-19.3%
-506.6%
Q3 25
-24.9%
-77.5%
Q2 25
-55.3%
-190.7%
Q1 25
-25.2%
-96.0%
Q4 24
-27.1%
-347.5%
Q3 24
-49.0%
-150.5%
Q2 24
-18.5%
-137.2%
Q1 24
-23.0%
-145.2%
Capex Intensity
OPK
OPK
RIOT
RIOT
Q4 25
1.8%
131.8%
Q3 25
2.1%
14.3%
Q2 25
2.1%
39.5%
Q1 25
2.1%
20.4%
Q4 24
2.9%
168.6%
Q3 24
4.6%
84.1%
Q2 24
4.0%
76.5%
Q1 24
2.6%
72.3%
Cash Conversion
OPK
OPK
RIOT
RIOT
Q4 25
Q3 25
-1.60×
-1.09×
Q2 25
-1.05×
Q1 25
Q4 24
-3.17×
-1.87×
Q3 24
-3.10×
Q2 24
Q1 24
-0.27×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

OPK
OPK

Services$71.1M48%
Transfer Of Intellectual Property And Other$33.7M23%
IE$22.1M15%
Rayaldee$8.8M6%
Barda Agreement$6.8M5%
MX$6.3M4%

RIOT
RIOT

Bitcoin Mining Segment$131.7M86%
Engineering Segment$21.1M14%

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