vs

Side-by-side financial comparison of OPKO HEALTH, INC. (OPK) and SL GREEN REALTY CORP (SLG). Click either name above to swap in a different company.

SL GREEN REALTY CORP is the larger business by last-quarter revenue ($276.5M vs $148.5M, roughly 1.9× OPKO HEALTH, INC.). OPKO HEALTH, INC. runs the higher net margin — -21.1% vs -36.5%, a 15.4% gap on every dollar of revenue. On growth, SL GREEN REALTY CORP posted the faster year-over-year revenue change (12.4% vs -19.2%). Over the past eight quarters, SL GREEN REALTY CORP's revenue compounded faster (21.3% CAGR vs -7.5%).

OPKO Health, Inc. is a medical test and medication company focused on diagnostics and pharmaceuticals. The company is a publicly traded company on NASDAQ and TASE under the symbol "OPK".

SL Green Realty Corp. is a real estate investment trust that primarily invests in office buildings and shopping centers in New York City. As of December 31, 2024, the company owned interests in 39 properties comprising 25,297,353 square feet, primarily in Manhattan. It has been referred to as "New York City’s largest office landlord".

OPK vs SLG — Head-to-Head

Bigger by revenue
SLG
SLG
1.9× larger
SLG
$276.5M
$148.5M
OPK
Growing faster (revenue YoY)
SLG
SLG
+31.6% gap
SLG
12.4%
-19.2%
OPK
Higher net margin
OPK
OPK
15.4% more per $
OPK
-21.1%
-36.5%
SLG
Faster 2-yr revenue CAGR
SLG
SLG
Annualised
SLG
21.3%
-7.5%
OPK

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
OPK
OPK
SLG
SLG
Revenue
$148.5M
$276.5M
Net Profit
$-31.3M
$-100.8M
Gross Margin
43.1%
Operating Margin
-25.8%
64.2%
Net Margin
-21.1%
-36.5%
Revenue YoY
-19.2%
12.4%
Net Profit YoY
-322.8%
-870.0%
EPS (diluted)
$-0.04
$-1.49

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
OPK
OPK
SLG
SLG
Q4 25
$148.5M
$276.5M
Q3 25
$151.7M
$244.8M
Q2 25
$156.8M
$241.9M
Q1 25
$150.0M
$239.8M
Q4 24
$183.6M
$245.9M
Q3 24
$173.6M
$229.7M
Q2 24
$182.2M
$222.8M
Q1 24
$173.7M
$187.9M
Net Profit
OPK
OPK
SLG
SLG
Q4 25
$-31.3M
$-100.8M
Q3 25
$21.6M
$28.6M
Q2 25
$-148.4M
$-7.4M
Q1 25
$-67.6M
$-17.3M
Q4 24
$14.0M
$19.1M
Q3 24
$24.9M
$-9.5M
Q2 24
$-10.3M
$1.6M
Q1 24
$-81.8M
$16.9M
Gross Margin
OPK
OPK
SLG
SLG
Q4 25
43.1%
Q3 25
32.9%
Q2 25
31.5%
Q1 25
28.4%
Q4 24
46.1%
Q3 24
23.1%
Q2 24
28.4%
Q1 24
24.2%
Operating Margin
OPK
OPK
SLG
SLG
Q4 25
-25.8%
64.2%
Q3 25
31.7%
85.5%
Q2 25
-38.3%
53.4%
Q1 25
-44.8%
56.7%
Q4 24
-18.0%
59.8%
Q3 24
8.2%
65.1%
Q2 24
-33.9%
79.2%
Q1 24
-41.2%
Net Margin
OPK
OPK
SLG
SLG
Q4 25
-21.1%
-36.5%
Q3 25
14.3%
11.7%
Q2 25
-94.7%
-3.0%
Q1 25
-45.1%
-7.2%
Q4 24
7.6%
7.8%
Q3 24
14.3%
-4.2%
Q2 24
-5.7%
0.7%
Q1 24
-47.1%
9.0%
EPS (diluted)
OPK
OPK
SLG
SLG
Q4 25
$-0.04
$-1.49
Q3 25
$0.03
$0.34
Q2 25
$-0.19
$-0.16
Q1 25
$-0.10
$-0.30
Q4 24
$0.02
$0.13
Q3 24
$0.03
$-0.21
Q2 24
$-0.01
$-0.04
Q1 24
$-0.12
$0.20

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
OPK
OPK
SLG
SLG
Cash + ST InvestmentsLiquidity on hand
$364.4M
$155.7M
Total DebtLower is stronger
$344.0M
Stockholders' EquityBook value
$1.3B
$3.7B
Total Assets
$1.9B
$11.1B
Debt / EquityLower = less leverage
0.27×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
OPK
OPK
SLG
SLG
Q4 25
$364.4M
$155.7M
Q3 25
$412.0M
$187.0M
Q2 25
$267.3M
$182.9M
Q1 25
$428.8M
$180.1M
Q4 24
$426.6M
$184.3M
Q3 24
$400.1M
$188.2M
Q2 24
$40.6M
$199.5M
Q1 24
$75.6M
$196.0M
Total Debt
OPK
OPK
SLG
SLG
Q4 25
$344.0M
Q3 25
$344.2M
Q2 25
$343.3M
Q1 25
$439.2M
Q4 24
$437.2M
Q3 24
$441.0M
Q2 24
$201.9M
Q1 24
$350.1M
Stockholders' Equity
OPK
OPK
SLG
SLG
Q4 25
$1.3B
$3.7B
Q3 25
$1.3B
$3.8B
Q2 25
$1.3B
$3.8B
Q1 25
$1.3B
$3.8B
Q4 24
$1.4B
$4.0B
Q3 24
$1.4B
$3.6B
Q2 24
$1.4B
$3.7B
Q1 24
$1.3B
$3.7B
Total Assets
OPK
OPK
SLG
SLG
Q4 25
$1.9B
$11.1B
Q3 25
$2.0B
$11.1B
Q2 25
$2.0B
$11.3B
Q1 25
$2.1B
$11.4B
Q4 24
$2.2B
$10.5B
Q3 24
$2.3B
$10.2B
Q2 24
$2.0B
$9.5B
Q1 24
$2.0B
$9.8B
Debt / Equity
OPK
OPK
SLG
SLG
Q4 25
0.27×
Q3 25
0.26×
Q2 25
0.26×
Q1 25
0.33×
Q4 24
0.32×
Q3 24
0.31×
Q2 24
0.14×
Q1 24
0.28×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
OPK
OPK
SLG
SLG
Operating Cash FlowLast quarter
$-25.9M
$82.9M
Free Cash FlowOCF − Capex
$-28.6M
FCF MarginFCF / Revenue
-19.3%
Capex IntensityCapex / Revenue
1.8%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-190.8M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
OPK
OPK
SLG
SLG
Q4 25
$-25.9M
$82.9M
Q3 25
$-34.6M
$-6.8M
Q2 25
$-83.4M
$54.5M
Q1 25
$-34.6M
$6.7M
Q4 24
$-44.4M
$129.6M
Q3 24
$-77.1M
$16.7M
Q2 24
$-26.4M
$79.4M
Q1 24
$-35.6M
$-24.7M
Free Cash Flow
OPK
OPK
SLG
SLG
Q4 25
$-28.6M
Q3 25
$-37.8M
Q2 25
$-86.7M
Q1 25
$-37.7M
Q4 24
$-49.8M
Q3 24
$-85.0M
Q2 24
$-33.7M
Q1 24
$-40.0M
FCF Margin
OPK
OPK
SLG
SLG
Q4 25
-19.3%
Q3 25
-24.9%
Q2 25
-55.3%
Q1 25
-25.2%
Q4 24
-27.1%
Q3 24
-49.0%
Q2 24
-18.5%
Q1 24
-23.0%
Capex Intensity
OPK
OPK
SLG
SLG
Q4 25
1.8%
Q3 25
2.1%
Q2 25
2.1%
Q1 25
2.1%
Q4 24
2.9%
Q3 24
4.6%
Q2 24
4.0%
Q1 24
2.6%
Cash Conversion
OPK
OPK
SLG
SLG
Q4 25
Q3 25
-1.60×
-0.24×
Q2 25
Q1 25
Q4 24
-3.17×
6.77×
Q3 24
-3.10×
Q2 24
50.33×
Q1 24
-1.46×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

OPK
OPK

Services$71.1M48%
Transfer Of Intellectual Property And Other$33.7M23%
IE$22.1M15%
Rayaldee$8.8M6%
Barda Agreement$6.8M5%
MX$6.3M4%

SLG
SLG

Real Estate Segment$223.1M81%
Other$35.9M13%
Debt And Preferred Equity Segment$17.4M6%

Related Comparisons