vs
Side-by-side financial comparison of OPKO HEALTH, INC. (OPK) and Vertex, Inc. (VERX). Click either name above to swap in a different company.
Vertex, Inc. is the larger business by last-quarter revenue ($196.6M vs $148.5M, roughly 1.3× OPKO HEALTH, INC.). Vertex, Inc. runs the higher net margin — -1.3% vs -21.1%, a 19.8% gap on every dollar of revenue. On growth, Vertex, Inc. posted the faster year-over-year revenue change (11.1% vs -19.2%). Vertex, Inc. produced more free cash flow last quarter ($7.7M vs $-28.6M). Over the past eight quarters, Vertex, Inc.'s revenue compounded faster (10.5% CAGR vs -7.5%).
OPKO Health, Inc. is a medical test and medication company focused on diagnostics and pharmaceuticals. The company is a publicly traded company on NASDAQ and TASE under the symbol "OPK".
Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, Oxfordshire, England.
OPK vs VERX — Head-to-Head
Income Statement — Q4 FY2025 vs Q1 FY2026
| Metric | | |
|---|---|---|
| Revenue | $148.5M | $196.6M |
| Net Profit | $-31.3M | $-2.5M |
| Gross Margin | 43.1% | 63.5% |
| Operating Margin | -25.8% | 31.1% |
| Net Margin | -21.1% | -1.3% |
| Revenue YoY | -19.2% | 11.1% |
| Net Profit YoY | -322.8% | -122.6% |
| EPS (diluted) | $-0.04 | $-0.02 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q1 26 | — | $196.6M | ||
| Q4 25 | $148.5M | $194.7M | ||
| Q3 25 | $151.7M | $192.1M | ||
| Q2 25 | $156.8M | $184.6M | ||
| Q1 25 | $150.0M | $177.1M | ||
| Q4 24 | $183.6M | $178.5M | ||
| Q3 24 | $173.6M | $170.4M | ||
| Q2 24 | $182.2M | $161.1M |
| Q1 26 | — | $-2.5M | ||
| Q4 25 | $-31.3M | $-7.0M | ||
| Q3 25 | $21.6M | $4.0M | ||
| Q2 25 | $-148.4M | $-961.0K | ||
| Q1 25 | $-67.6M | $11.1M | ||
| Q4 24 | $14.0M | $-67.8M | ||
| Q3 24 | $24.9M | $7.2M | ||
| Q2 24 | $-10.3M | $5.2M |
| Q1 26 | — | 63.5% | ||
| Q4 25 | 43.1% | 64.8% | ||
| Q3 25 | 32.9% | 63.1% | ||
| Q2 25 | 31.5% | 65.7% | ||
| Q1 25 | 28.4% | 63.8% | ||
| Q4 24 | 46.1% | 65.6% | ||
| Q3 24 | 23.1% | 64.8% | ||
| Q2 24 | 28.4% | 63.7% |
| Q1 26 | — | 31.1% | ||
| Q4 25 | -25.8% | -1.3% | ||
| Q3 25 | 31.7% | 2.2% | ||
| Q2 25 | -38.3% | -2.1% | ||
| Q1 25 | -44.8% | 2.5% | ||
| Q4 24 | -18.0% | -7.3% | ||
| Q3 24 | 8.2% | 2.9% | ||
| Q2 24 | -33.9% | 4.7% |
| Q1 26 | — | -1.3% | ||
| Q4 25 | -21.1% | -3.6% | ||
| Q3 25 | 14.3% | 2.1% | ||
| Q2 25 | -94.7% | -0.5% | ||
| Q1 25 | -45.1% | 6.3% | ||
| Q4 24 | 7.6% | -38.0% | ||
| Q3 24 | 14.3% | 4.2% | ||
| Q2 24 | -5.7% | 3.2% |
| Q1 26 | — | $-0.02 | ||
| Q4 25 | $-0.04 | — | ||
| Q3 25 | $0.03 | — | ||
| Q2 25 | $-0.19 | — | ||
| Q1 25 | $-0.10 | — | ||
| Q4 24 | $0.02 | — | ||
| Q3 24 | $0.03 | — | ||
| Q2 24 | $-0.01 | — |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $364.4M | $252.5M |
| Total DebtLower is stronger | $344.0M | — |
| Stockholders' EquityBook value | $1.3B | $246.5M |
| Total Assets | $1.9B | $1.2B |
| Debt / EquityLower = less leverage | 0.27× | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | — | $252.5M | ||
| Q4 25 | $364.4M | $314.0M | ||
| Q3 25 | $412.0M | $313.5M | ||
| Q2 25 | $267.3M | $284.4M | ||
| Q1 25 | $428.8M | $270.4M | ||
| Q4 24 | $426.6M | $296.1M | ||
| Q3 24 | $400.1M | $279.0M | ||
| Q2 24 | $40.6M | $325.5M |
| Q1 26 | — | — | ||
| Q4 25 | $344.0M | $337.5M | ||
| Q3 25 | $344.2M | $336.9M | ||
| Q2 25 | $343.3M | $336.3M | ||
| Q1 25 | $439.2M | $335.8M | ||
| Q4 24 | $437.2M | $335.2M | ||
| Q3 24 | $441.0M | $334.7M | ||
| Q2 24 | $201.9M | $334.1M |
| Q1 26 | — | $246.5M | ||
| Q4 25 | $1.3B | $258.9M | ||
| Q3 25 | $1.3B | $264.5M | ||
| Q2 25 | $1.3B | $248.0M | ||
| Q1 25 | $1.3B | $200.5M | ||
| Q4 24 | $1.4B | $179.4M | ||
| Q3 24 | $1.4B | $259.0M | ||
| Q2 24 | $1.4B | $233.1M |
| Q1 26 | — | $1.2B | ||
| Q4 25 | $1.9B | $1.3B | ||
| Q3 25 | $2.0B | $1.2B | ||
| Q2 25 | $2.0B | $1.2B | ||
| Q1 25 | $2.1B | $1.2B | ||
| Q4 24 | $2.2B | $1.2B | ||
| Q3 24 | $2.3B | $1.2B | ||
| Q2 24 | $2.0B | $1.0B |
| Q1 26 | — | — | ||
| Q4 25 | 0.27× | 1.30× | ||
| Q3 25 | 0.26× | 1.27× | ||
| Q2 25 | 0.26× | 1.36× | ||
| Q1 25 | 0.33× | 1.67× | ||
| Q4 24 | 0.32× | 1.87× | ||
| Q3 24 | 0.31× | 1.29× | ||
| Q2 24 | 0.14× | 1.43× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-25.9M | $38.0M |
| Free Cash FlowOCF − Capex | $-28.6M | $7.7M |
| FCF MarginFCF / Revenue | -19.3% | 3.9% |
| Capex IntensityCapex / Revenue | 1.8% | — |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $-190.8M | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | — | $38.0M | ||
| Q4 25 | $-25.9M | $42.3M | ||
| Q3 25 | $-34.6M | $62.5M | ||
| Q2 25 | $-83.4M | $46.0M | ||
| Q1 25 | $-34.6M | $14.8M | ||
| Q4 24 | $-44.4M | $41.1M | ||
| Q3 24 | $-77.1M | $41.4M | ||
| Q2 24 | $-26.4M | $57.7M |
| Q1 26 | — | $7.7M | ||
| Q4 25 | $-28.6M | — | ||
| Q3 25 | $-37.8M | — | ||
| Q2 25 | $-86.7M | — | ||
| Q1 25 | $-37.7M | — | ||
| Q4 24 | $-49.8M | — | ||
| Q3 24 | $-85.0M | $-24.3M | ||
| Q2 24 | $-33.7M | — |
| Q1 26 | — | 3.9% | ||
| Q4 25 | -19.3% | — | ||
| Q3 25 | -24.9% | — | ||
| Q2 25 | -55.3% | — | ||
| Q1 25 | -25.2% | — | ||
| Q4 24 | -27.1% | — | ||
| Q3 24 | -49.0% | -14.2% | ||
| Q2 24 | -18.5% | — |
| Q1 26 | — | — | ||
| Q4 25 | 1.8% | — | ||
| Q3 25 | 2.1% | — | ||
| Q2 25 | 2.1% | — | ||
| Q1 25 | 2.1% | — | ||
| Q4 24 | 2.9% | — | ||
| Q3 24 | 4.6% | 38.5% | ||
| Q2 24 | 4.0% | — |
| Q1 26 | — | — | ||
| Q4 25 | — | — | ||
| Q3 25 | -1.60× | 15.44× | ||
| Q2 25 | — | — | ||
| Q1 25 | — | 1.33× | ||
| Q4 24 | -3.17× | — | ||
| Q3 24 | -3.10× | 5.73× | ||
| Q2 24 | — | 11.18× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
OPK
| Services | $71.1M | 48% |
| Transfer Of Intellectual Property And Other | $33.7M | 23% |
| IE | $22.1M | 15% |
| Rayaldee | $8.8M | 6% |
| Barda Agreement | $6.8M | 5% |
| MX | $6.3M | 4% |
VERX
| Software subscriptions | $167.1M | 85% |
| Services | $29.5M | 15% |
