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Side-by-side financial comparison of OCTAVE SPECIALTY GROUP INC (OSG) and Twist Bioscience Corp (TWST). Click either name above to swap in a different company.

OCTAVE SPECIALTY GROUP INC is the larger business by last-quarter revenue ($104.2M vs $103.7M, roughly 1.0× Twist Bioscience Corp). OCTAVE SPECIALTY GROUP INC runs the higher net margin — -6.6% vs -29.4%, a 22.8% gap on every dollar of revenue. On growth, OCTAVE SPECIALTY GROUP INC posted the faster year-over-year revenue change (66.0% vs 16.9%).

Octave Specialty Group Inc. is a specialty insurance holding company that provides tailored property and casualty insurance products. Its core business focuses on excess and surplus lines, catering to commercial and individual clients across primary North American markets with customized risk coverage solutions.

Twist Bioscience is a public biotechnology company based in South San Francisco that manufactures synthetic DNA and DNA products for customers in a wide range of industries. Twist was founded in 2013 by Emily Leproust, Bill Banyai, and Bill Peck.

OSG vs TWST — Head-to-Head

Bigger by revenue
OSG
OSG
1.0× larger
OSG
$104.2M
$103.7M
TWST
Growing faster (revenue YoY)
OSG
OSG
+49.1% gap
OSG
66.0%
16.9%
TWST
Higher net margin
OSG
OSG
22.8% more per $
OSG
-6.6%
-29.4%
TWST

Income Statement — Q1 FY2026 vs Q1 FY2026

Metric
OSG
OSG
TWST
TWST
Revenue
$104.2M
$103.7M
Net Profit
$-6.9M
$-30.5M
Gross Margin
52.0%
Operating Margin
-31.7%
Net Margin
-6.6%
-29.4%
Revenue YoY
66.0%
16.9%
Net Profit YoY
3.4%
EPS (diluted)
$-0.13
$-0.50

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
OSG
OSG
TWST
TWST
Q1 26
$104.2M
Q4 25
$66.9M
$103.7M
Q3 25
$66.6M
Q2 25
$55.0M
Q1 25
$62.8M
Q4 24
$65.2M
Q3 24
$70.0M
Q2 24
$51.0M
Net Profit
OSG
OSG
TWST
TWST
Q1 26
$-6.9M
Q4 25
$-29.7M
$-30.5M
Q3 25
$-112.6M
Q2 25
$-72.7M
Q1 25
$-44.7M
Q4 24
$-20.9M
Q3 24
$-27.5M
Q2 24
$-750.0K
Gross Margin
OSG
OSG
TWST
TWST
Q1 26
Q4 25
52.0%
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Operating Margin
OSG
OSG
TWST
TWST
Q1 26
Q4 25
-76.7%
-31.7%
Q3 25
-48.2%
Q2 25
-41.8%
Q1 25
-24.1%
Q4 24
-55.5%
Q3 24
-29.7%
Q2 24
-28.9%
Net Margin
OSG
OSG
TWST
TWST
Q1 26
-6.6%
Q4 25
-73.8%
-29.4%
Q3 25
-169.1%
Q2 25
-132.3%
Q1 25
-71.3%
Q4 24
-55.1%
Q3 24
-39.3%
Q2 24
-1.5%
EPS (diluted)
OSG
OSG
TWST
TWST
Q1 26
$-0.13
Q4 25
$-0.82
$-0.50
Q3 25
$-2.35
Q2 25
$-1.54
Q1 25
$-1.22
Q4 24
$-11.75
Q3 24
$-0.63
Q2 24
$-0.02

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
OSG
OSG
TWST
TWST
Cash + ST InvestmentsLiquidity on hand
$197.9M
Total DebtLower is stronger
$117.1M
Stockholders' EquityBook value
$833.6M
$456.1M
Total Assets
$2.3B
$638.1M
Debt / EquityLower = less leverage
0.14×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
OSG
OSG
TWST
TWST
Q1 26
Q4 25
$146.4M
$197.9M
Q3 25
$27.5M
Q2 25
$22.5M
Q1 25
$34.1M
Q4 24
$157.2M
Q3 24
$40.8M
Q2 24
$14.6M
Total Debt
OSG
OSG
TWST
TWST
Q1 26
$117.1M
Q4 25
$117.6M
Q3 25
Q2 25
Q1 25
Q4 24
$0
Q3 24
$518.0M
Q2 24
$515.0M
Stockholders' Equity
OSG
OSG
TWST
TWST
Q1 26
$833.6M
Q4 25
$715.8M
$456.1M
Q3 25
$843.4M
Q2 25
$859.8M
Q1 25
$852.2M
Q4 24
$798.4M
Q3 24
$1.5B
Q2 24
$1.4B
Total Assets
OSG
OSG
TWST
TWST
Q1 26
$2.3B
Q4 25
$2.2B
$638.1M
Q3 25
$2.1B
Q2 25
$8.5B
Q1 25
$8.3B
Q4 24
$8.1B
Q3 24
$9.3B
Q2 24
$8.2B
Debt / Equity
OSG
OSG
TWST
TWST
Q1 26
0.14×
Q4 25
0.16×
Q3 25
Q2 25
Q1 25
Q4 24
0.00×
Q3 24
0.35×
Q2 24
0.38×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
OSG
OSG
TWST
TWST
Operating Cash FlowLast quarter
$-24.8M
Free Cash FlowOCF − Capex
$-34.8M
FCF MarginFCF / Revenue
-33.5%
Capex IntensityCapex / Revenue
9.6%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
OSG
OSG
TWST
TWST
Q1 26
Q4 25
$-52.3M
$-24.8M
Q3 25
$-41.2M
Q2 25
$2.1M
Q1 25
$-12.6M
Q4 24
$762.0K
Q3 24
$48.9M
Q2 24
$20.4M
Free Cash Flow
OSG
OSG
TWST
TWST
Q1 26
Q4 25
$-34.8M
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
FCF Margin
OSG
OSG
TWST
TWST
Q1 26
Q4 25
-33.5%
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Capex Intensity
OSG
OSG
TWST
TWST
Q1 26
Q4 25
9.6%
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

OSG
OSG

Commissions$68.2M65%
Other$20.6M20%
Servicing and other fees$9.4M9%
Program fees$3.6M3%
Investment income$2.4M2%

TWST
TWST

Industrial Chemicals$37.2M36%
Diagnostics$35.3M34%
Food Or Agriculture$12.8M12%
Academic Research$12.2M12%
Health Care$6.1M6%

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