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Side-by-side financial comparison of PENN Entertainment, Inc. (PENN) and Vertex Pharmaceuticals (VRTX). Click either name above to swap in a different company.

Vertex Pharmaceuticals is the larger business by last-quarter revenue ($3.2B vs $1.8B, roughly 1.8× PENN Entertainment, Inc.). Vertex Pharmaceuticals runs the higher net margin — 37.3% vs -0.2%, a 37.5% gap on every dollar of revenue. On growth, Vertex Pharmaceuticals posted the faster year-over-year revenue change (9.5% vs 6.4%). Over the past eight quarters, Vertex Pharmaceuticals's revenue compounded faster (8.9% CAGR vs 3.4%).

Penn Entertainment, Inc., formerly Penn National Gaming, is an American entertainment company and operator of integrated entertainment, sports content, and casino gambling. It operates 43 properties in 20 states, under brands including Hollywood Casino, Ameristar, and Boomtown. It also owns the Canadian digital media company Score Media and Gaming.

Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, Oxfordshire, England.

PENN vs VRTX — Head-to-Head

Bigger by revenue
VRTX
VRTX
1.8× larger
VRTX
$3.2B
$1.8B
PENN
Growing faster (revenue YoY)
VRTX
VRTX
+3.2% gap
VRTX
9.5%
6.4%
PENN
Higher net margin
VRTX
VRTX
37.5% more per $
VRTX
37.3%
-0.2%
PENN
Faster 2-yr revenue CAGR
VRTX
VRTX
Annualised
VRTX
8.9%
3.4%
PENN

Income Statement — Q1 FY2026 vs Q4 FY2025

Metric
PENN
PENN
VRTX
VRTX
Revenue
$1.8B
$3.2B
Net Profit
$-2.8M
$1.2B
Gross Margin
85.4%
Operating Margin
5.5%
37.8%
Net Margin
-0.2%
37.3%
Revenue YoY
6.4%
9.5%
Net Profit YoY
30.5%
EPS (diluted)
$-0.02
$4.64

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
PENN
PENN
VRTX
VRTX
Q1 26
$1.8B
Q4 25
$1.8B
$3.2B
Q3 25
$1.7B
$3.1B
Q2 25
$1.8B
$3.0B
Q1 25
$1.7B
$2.8B
Q4 24
$1.7B
$2.9B
Q3 24
$1.6B
$2.8B
Q2 24
$1.7B
$2.6B
Net Profit
PENN
PENN
VRTX
VRTX
Q1 26
$-2.8M
Q4 25
$-72.9M
$1.2B
Q3 25
$-864.6M
$1.1B
Q2 25
$-17.4M
$1.0B
Q1 25
$111.8M
$646.3M
Q4 24
$-133.3M
$913.0M
Q3 24
$-36.7M
$1.0B
Q2 24
$-26.8M
$-3.6B
Gross Margin
PENN
PENN
VRTX
VRTX
Q1 26
Q4 25
85.4%
Q3 25
86.5%
Q2 25
86.3%
Q1 25
86.9%
Q4 24
85.5%
Q3 24
85.8%
Q2 24
85.9%
Operating Margin
PENN
PENN
VRTX
VRTX
Q1 26
5.5%
Q4 25
-1.0%
37.8%
Q3 25
-45.2%
38.6%
Q2 25
4.4%
38.8%
Q1 25
2.6%
22.7%
Q4 24
-2.9%
35.2%
Q3 24
4.1%
40.3%
Q2 24
4.5%
-132.9%
Net Margin
PENN
PENN
VRTX
VRTX
Q1 26
-0.2%
Q4 25
-4.0%
37.3%
Q3 25
-50.3%
35.2%
Q2 25
-1.0%
34.8%
Q1 25
6.7%
23.3%
Q4 24
-8.0%
31.4%
Q3 24
-2.2%
37.7%
Q2 24
-1.6%
-135.8%
EPS (diluted)
PENN
PENN
VRTX
VRTX
Q1 26
$-0.02
Q4 25
$-0.36
$4.64
Q3 25
$-6.03
$4.20
Q2 25
$-0.12
$3.99
Q1 25
$0.68
$2.49
Q4 24
$-0.87
$3.62
Q3 24
$-0.24
$4.01
Q2 24
$-0.18
$-13.92

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
PENN
PENN
VRTX
VRTX
Cash + ST InvestmentsLiquidity on hand
$708.0M
$6.6B
Total DebtLower is stronger
Stockholders' EquityBook value
$18.7B
Total Assets
$25.6B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
PENN
PENN
VRTX
VRTX
Q1 26
$708.0M
Q4 25
$686.6M
$6.6B
Q3 25
$660.1M
$6.3B
Q2 25
$671.6M
$6.4B
Q1 25
$591.6M
$6.2B
Q4 24
$706.6M
$6.1B
Q3 24
$834.0M
$6.5B
Q2 24
$877.6M
$5.8B
Total Debt
PENN
PENN
VRTX
VRTX
Q1 26
Q4 25
$2.9B
Q3 25
$2.9B
Q2 25
$2.8B
Q1 25
$2.6B
Q4 24
$2.8B
Q3 24
$2.8B
Q2 24
$2.8B
Stockholders' Equity
PENN
PENN
VRTX
VRTX
Q1 26
Q4 25
$1.8B
$18.7B
Q3 25
$2.0B
$17.3B
Q2 25
$3.0B
$17.2B
Q1 25
$3.0B
$16.5B
Q4 24
$2.9B
$16.4B
Q3 24
$3.1B
$15.6B
Q2 24
$3.1B
$14.8B
Total Assets
PENN
PENN
VRTX
VRTX
Q1 26
Q4 25
$14.3B
$25.6B
Q3 25
$14.3B
$24.9B
Q2 25
$15.2B
$24.0B
Q1 25
$15.1B
$22.9B
Q4 24
$15.3B
$22.5B
Q3 24
$15.5B
$22.2B
Q2 24
$15.5B
$20.1B
Debt / Equity
PENN
PENN
VRTX
VRTX
Q1 26
Q4 25
1.58×
Q3 25
1.46×
Q2 25
0.94×
Q1 25
0.89×
Q4 24
0.98×
Q3 24
0.91×
Q2 24
0.91×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
PENN
PENN
VRTX
VRTX
Operating Cash FlowLast quarter
$498.0M
Free Cash FlowOCF − Capex
$348.6M
FCF MarginFCF / Revenue
10.9%
Capex IntensityCapex / Revenue
5.3%
4.7%
Cash ConversionOCF / Net Profit
0.42×
TTM Free Cash FlowTrailing 4 quarters
$3.2B

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
PENN
PENN
VRTX
VRTX
Q1 26
Q4 25
$107.2M
$498.0M
Q3 25
$180.9M
$1.2B
Q2 25
$178.2M
$1.1B
Q1 25
$41.9M
$818.9M
Q4 24
$102.9M
$584.6M
Q3 24
$174.7M
$1.4B
Q2 24
$150.4M
$-3.8B
Free Cash Flow
PENN
PENN
VRTX
VRTX
Q1 26
Q4 25
$-83.2M
$348.6M
Q3 25
$8.2M
$1.1B
Q2 25
$18.8M
$927.4M
Q1 25
$-83.3M
$778.2M
Q4 24
$-118.1M
$492.0M
Q3 24
$42.6M
$1.3B
Q2 24
$62.2M
$-3.8B
FCF Margin
PENN
PENN
VRTX
VRTX
Q1 26
Q4 25
-4.6%
10.9%
Q3 25
0.5%
37.0%
Q2 25
1.1%
31.3%
Q1 25
-5.0%
28.1%
Q4 24
-7.1%
16.9%
Q3 24
2.6%
47.0%
Q2 24
3.7%
-144.5%
Capex Intensity
PENN
PENN
VRTX
VRTX
Q1 26
5.3%
Q4 25
10.5%
4.7%
Q3 25
10.1%
3.3%
Q2 25
9.0%
4.9%
Q1 25
7.5%
1.5%
Q4 24
13.2%
3.2%
Q3 24
8.1%
2.4%
Q2 24
5.3%
2.6%
Cash Conversion
PENN
PENN
VRTX
VRTX
Q1 26
Q4 25
0.42×
Q3 25
1.15×
Q2 25
1.04×
Q1 25
0.37×
1.27×
Q4 24
0.64×
Q3 24
1.31×
Q2 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

PENN
PENN

Northeast segment (1)$687.1M39%
Interactive (5)$358.3M20%
Midwest segment (4)$305.9M17%
South segment (2)$281.3M16%
West segment (3)$145.8M8%

VRTX
VRTX

TRIKAFTAKAFTRIO$2.6B81%
ALYFTREK$380.1M12%
Manufactured Product Other$237.4M7%

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