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Side-by-side financial comparison of PPL Corporation (PPL) and Vertex Pharmaceuticals (VRTX). Click either name above to swap in a different company.

Vertex Pharmaceuticals is the larger business by last-quarter revenue ($3.2B vs $2.3B, roughly 1.4× PPL Corporation). Vertex Pharmaceuticals runs the higher net margin — 37.3% vs 11.3%, a 26.0% gap on every dollar of revenue. On growth, Vertex Pharmaceuticals posted the faster year-over-year revenue change (9.5% vs 7.2%). Vertex Pharmaceuticals produced more free cash flow last quarter ($348.6M vs $-614.0M). Over the past eight quarters, Vertex Pharmaceuticals's revenue compounded faster (8.9% CAGR vs 1.0%).

PPL Corporation is a leading US-based energy utility holding company headquartered in Allentown, Pennsylvania. It delivers electricity and natural gas to approximately 3.5 million residential, commercial and industrial customers across Pennsylvania, Kentucky and Rhode Island, with core focuses on grid modernization, affordable clean energy transition, and reliable sustainable energy services for local communities.

Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, Oxfordshire, England.

PPL vs VRTX — Head-to-Head

Bigger by revenue
VRTX
VRTX
1.4× larger
VRTX
$3.2B
$2.3B
PPL
Growing faster (revenue YoY)
VRTX
VRTX
+2.3% gap
VRTX
9.5%
7.2%
PPL
Higher net margin
VRTX
VRTX
26.0% more per $
VRTX
37.3%
11.3%
PPL
More free cash flow
VRTX
VRTX
$962.6M more FCF
VRTX
$348.6M
$-614.0M
PPL
Faster 2-yr revenue CAGR
VRTX
VRTX
Annualised
VRTX
8.9%
1.0%
PPL

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
PPL
PPL
VRTX
VRTX
Revenue
$2.3B
$3.2B
Net Profit
$266.0M
$1.2B
Gross Margin
85.4%
Operating Margin
20.3%
37.8%
Net Margin
11.3%
37.3%
Revenue YoY
7.2%
9.5%
Net Profit YoY
50.3%
30.5%
EPS (diluted)
$0.35
$4.64

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
PPL
PPL
VRTX
VRTX
Q4 25
$2.3B
$3.2B
Q3 25
$2.2B
$3.1B
Q2 25
$2.0B
$3.0B
Q1 25
$2.5B
$2.8B
Q4 24
$2.2B
$2.9B
Q3 24
$2.1B
$2.8B
Q2 24
$1.9B
$2.6B
Q1 24
$2.3B
$2.7B
Net Profit
PPL
PPL
VRTX
VRTX
Q4 25
$266.0M
$1.2B
Q3 25
$318.0M
$1.1B
Q2 25
$183.0M
$1.0B
Q1 25
$414.0M
$646.3M
Q4 24
$177.0M
$913.0M
Q3 24
$214.0M
$1.0B
Q2 24
$190.0M
$-3.6B
Q1 24
$307.0M
$1.1B
Gross Margin
PPL
PPL
VRTX
VRTX
Q4 25
85.4%
Q3 25
86.5%
Q2 25
86.3%
Q1 25
86.9%
Q4 24
85.5%
Q3 24
85.8%
Q2 24
85.9%
Q1 24
87.3%
Operating Margin
PPL
PPL
VRTX
VRTX
Q4 25
20.3%
37.8%
Q3 25
25.4%
38.6%
Q2 25
19.9%
38.8%
Q1 25
26.6%
22.7%
Q4 24
17.2%
35.2%
Q3 24
20.6%
40.3%
Q2 24
20.8%
-132.9%
Q1 24
23.7%
42.4%
Net Margin
PPL
PPL
VRTX
VRTX
Q4 25
11.3%
37.3%
Q3 25
14.2%
35.2%
Q2 25
9.0%
34.8%
Q1 25
16.3%
23.3%
Q4 24
8.1%
31.4%
Q3 24
10.3%
37.7%
Q2 24
10.1%
-135.8%
Q1 24
13.3%
40.9%
EPS (diluted)
PPL
PPL
VRTX
VRTX
Q4 25
$0.35
$4.64
Q3 25
$0.43
$4.20
Q2 25
$0.25
$3.99
Q1 25
$0.56
$2.49
Q4 24
$0.23
$3.62
Q3 24
$0.29
$4.01
Q2 24
$0.26
$-13.92
Q1 24
$0.42
$4.21

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
PPL
PPL
VRTX
VRTX
Cash + ST InvestmentsLiquidity on hand
$1.1B
$6.6B
Total DebtLower is stronger
$18.9B
Stockholders' EquityBook value
$14.9B
$18.7B
Total Assets
$45.2B
$25.6B
Debt / EquityLower = less leverage
1.27×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
PPL
PPL
VRTX
VRTX
Q4 25
$1.1B
$6.6B
Q3 25
$1.1B
$6.3B
Q2 25
$294.0M
$6.4B
Q1 25
$312.0M
$6.2B
Q4 24
$306.0M
$6.1B
Q3 24
$542.0M
$6.5B
Q2 24
$282.0M
$5.8B
Q1 24
$276.0M
$10.2B
Total Debt
PPL
PPL
VRTX
VRTX
Q4 25
$18.9B
Q3 25
Q2 25
Q1 25
Q4 24
$16.5B
Q3 24
Q2 24
Q1 24
Stockholders' Equity
PPL
PPL
VRTX
VRTX
Q4 25
$14.9B
$18.7B
Q3 25
$14.4B
$17.3B
Q2 25
$14.3B
$17.2B
Q1 25
$14.3B
$16.5B
Q4 24
$14.1B
$16.4B
Q3 24
$14.1B
$15.6B
Q2 24
$14.1B
$14.8B
Q1 24
$14.1B
$18.5B
Total Assets
PPL
PPL
VRTX
VRTX
Q4 25
$45.2B
$25.6B
Q3 25
$43.9B
$24.9B
Q2 25
$42.4B
$24.0B
Q1 25
$41.8B
$22.9B
Q4 24
$41.1B
$22.5B
Q3 24
$40.5B
$22.2B
Q2 24
$39.8B
$20.1B
Q1 24
$39.6B
$23.9B
Debt / Equity
PPL
PPL
VRTX
VRTX
Q4 25
1.27×
Q3 25
Q2 25
Q1 25
Q4 24
1.17×
Q3 24
Q2 24
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
PPL
PPL
VRTX
VRTX
Operating Cash FlowLast quarter
$548.0M
$498.0M
Free Cash FlowOCF − Capex
$-614.0M
$348.6M
FCF MarginFCF / Revenue
-26.1%
10.9%
Capex IntensityCapex / Revenue
49.5%
4.7%
Cash ConversionOCF / Net Profit
2.06×
0.42×
TTM Free Cash FlowTrailing 4 quarters
$-1.4B
$3.2B

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
PPL
PPL
VRTX
VRTX
Q4 25
$548.0M
$498.0M
Q3 25
$966.0M
$1.2B
Q2 25
$602.0M
$1.1B
Q1 25
$513.0M
$818.9M
Q4 24
$511.0M
$584.6M
Q3 24
$781.0M
$1.4B
Q2 24
$766.0M
$-3.8B
Q1 24
$282.0M
$1.3B
Free Cash Flow
PPL
PPL
VRTX
VRTX
Q4 25
$-614.0M
$348.6M
Q3 25
$-179.0M
$1.1B
Q2 25
$-328.0M
$927.4M
Q1 25
$-280.0M
$778.2M
Q4 24
$-349.0M
$492.0M
Q3 24
$102.0M
$1.3B
Q2 24
$96.0M
$-3.8B
Q1 24
$-314.0M
$1.2B
FCF Margin
PPL
PPL
VRTX
VRTX
Q4 25
-26.1%
10.9%
Q3 25
-8.0%
37.0%
Q2 25
-16.1%
31.3%
Q1 25
-11.0%
28.1%
Q4 24
-15.9%
16.9%
Q3 24
4.9%
47.0%
Q2 24
5.1%
-144.5%
Q1 24
-13.6%
46.0%
Capex Intensity
PPL
PPL
VRTX
VRTX
Q4 25
49.5%
4.7%
Q3 25
51.2%
3.3%
Q2 25
45.6%
4.9%
Q1 25
31.2%
1.5%
Q4 24
39.3%
3.2%
Q3 24
32.7%
2.4%
Q2 24
35.8%
2.6%
Q1 24
25.9%
2.5%
Cash Conversion
PPL
PPL
VRTX
VRTX
Q4 25
2.06×
0.42×
Q3 25
3.04×
1.15×
Q2 25
3.29×
1.04×
Q1 25
1.24×
1.27×
Q4 24
2.89×
0.64×
Q3 24
3.65×
1.31×
Q2 24
4.03×
Q1 24
0.92×
1.19×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

PPL
PPL

Rhode Island Regulated$539.0M23%
Other$532.0M23%
Residential$451.0M19%
Nonrelated Party$425.0M18%
Transmission$228.0M10%
Commercial$117.0M5%
Wholesale Other$23.0M1%
Industrial$14.0M1%
Related Party$13.0M1%
Wholesale Municipal$6.0M0%

VRTX
VRTX

TRIKAFTAKAFTRIO$2.6B81%
ALYFTREK$380.1M12%
Manufactured Product Other$237.4M7%

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