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Side-by-side financial comparison of PROTHENA CORP PUBLIC LTD CO (PRTA) and ROCKET PHARMACEUTICALS, INC. (RCKT). Click either name above to swap in a different company.

Prothena Corporation plc is a late-stage clinical biotechnology firm focused on developing and commercializing innovative antibody therapies for neurodegenerative disorders, rare diseases and immune-related conditions. Its core pipeline targets unmet medical needs including amyloidosis, Parkinson's and Alzheimer's, serving key markets across North America, Europe and the Asia-Pacific.

Rocket Pharmaceuticals, Inc. is a clinical-stage biotechnology company focused on developing first-in-class adeno-associated virus (AAV) and lentiviral-based gene therapies for rare, orphan genetic disorders with high unmet medical need. It primarily operates across the U.S. and European markets, with pipeline candidates targeting hematologic, neurological, and pediatric genetic conditions.

PRTA vs RCKT — Head-to-Head

Bigger by revenue
PRTA
PRTA
Infinity× larger
PRTA
$21.0K
$0
RCKT

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
PRTA
PRTA
RCKT
RCKT
Revenue
$21.0K
$0
Net Profit
Gross Margin
Operating Margin
Net Margin
Revenue YoY
-99.0%
Net Profit YoY
62.7%
EPS (diluted)
$-0.38

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
PRTA
PRTA
RCKT
RCKT
Q4 25
$21.0K
$0
Q3 25
$2.4M
$0
Q2 25
$4.4M
$0
Q1 25
$2.8M
$0
Q4 24
$2.1M
$0
Q3 24
$970.0K
$0
Q2 24
$132.0M
$0
Q1 24
$50.0K
$0
Net Profit
PRTA
PRTA
RCKT
RCKT
Q4 25
Q3 25
$-36.5M
$-50.3M
Q2 25
$-125.8M
$-68.9M
Q1 25
$-60.2M
$-61.3M
Q4 24
Q3 24
$-59.0M
$-66.7M
Q2 24
$66.9M
$-69.6M
Q1 24
$-72.2M
$-62.1M
Operating Margin
PRTA
PRTA
RCKT
RCKT
Q4 25
Q3 25
-1666.3%
Q2 25
-1914.4%
Q1 25
-2319.0%
Q4 24
Q3 24
-6857.0%
Q2 24
44.2%
Q1 24
-163056.0%
Net Margin
PRTA
PRTA
RCKT
RCKT
Q4 25
Q3 25
-1513.1%
Q2 25
-2845.4%
Q1 25
-2128.5%
Q4 24
Q3 24
-6082.6%
Q2 24
50.7%
Q1 24
-144478.0%
EPS (diluted)
PRTA
PRTA
RCKT
RCKT
Q4 25
$-0.38
Q3 25
$-0.68
$-0.45
Q2 25
$-2.34
$-0.62
Q1 25
$-1.12
$-0.56
Q4 24
$-0.62
Q3 24
$-1.10
$-0.71
Q2 24
$1.22
$-0.74
Q1 24
$-1.34
$-0.66

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
PRTA
PRTA
RCKT
RCKT
Cash + ST InvestmentsLiquidity on hand
$307.5M
$188.9M
Total DebtLower is stronger
Stockholders' EquityBook value
$280.5M
$277.2M
Total Assets
$326.8M
$330.4M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
PRTA
PRTA
RCKT
RCKT
Q4 25
$307.5M
$188.9M
Q3 25
$330.8M
$222.8M
Q2 25
$371.4M
$271.5M
Q1 25
$417.9M
$318.2M
Q4 24
$471.4M
$372.3M
Q3 24
$519.3M
$235.7M
Q2 24
$564.1M
$278.8M
Q1 24
$546.5M
$330.3M
Stockholders' Equity
PRTA
PRTA
RCKT
RCKT
Q4 25
$280.5M
$277.2M
Q3 25
$295.0M
$313.7M
Q2 25
$324.3M
$354.2M
Q1 25
$437.7M
$412.1M
Q4 24
$486.9M
$463.2M
Q3 24
$534.4M
$329.8M
Q2 24
$581.9M
$384.6M
Q1 24
$502.4M
$441.5M
Total Assets
PRTA
PRTA
RCKT
RCKT
Q4 25
$326.8M
$330.4M
Q3 25
$352.6M
$368.0M
Q2 25
$399.1M
$421.0M
Q1 25
$495.3M
$471.1M
Q4 24
$547.1M
$527.7M
Q3 24
$595.3M
$393.7M
Q2 24
$645.6M
$446.4M
Q1 24
$623.2M
$499.4M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
PRTA
PRTA
RCKT
RCKT
Operating Cash FlowLast quarter
$-163.6M
$-34.8M
Free Cash FlowOCF − Capex
$-34.9M
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-190.6M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
PRTA
PRTA
RCKT
RCKT
Q4 25
$-163.6M
$-34.8M
Q3 25
$-40.6M
$-50.4M
Q2 25
$-46.3M
$-49.0M
Q1 25
$-53.4M
$-55.8M
Q4 24
$-150.1M
$-46.9M
Q3 24
$-45.2M
$-52.1M
Q2 24
$16.0M
$-53.8M
Q1 24
$-73.1M
$-56.9M
Free Cash Flow
PRTA
PRTA
RCKT
RCKT
Q4 25
$-34.9M
Q3 25
$-50.5M
Q2 25
$-49.0M
Q1 25
$-56.2M
Q4 24
$-47.3M
Q3 24
$-53.7M
Q2 24
$-55.8M
Q1 24
$-58.9M
Cash Conversion
PRTA
PRTA
RCKT
RCKT
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
0.24×
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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