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Side-by-side financial comparison of PTC THERAPEUTICS, INC. (PTCT) and QUALYS, INC. (QLYS). Click either name above to swap in a different company.
QUALYS, INC. is the larger business by last-quarter revenue ($175.3M vs $164.7M, roughly 1.1× PTC THERAPEUTICS, INC.). QUALYS, INC. runs the higher net margin — 30.3% vs -82.0%, a 112.3% gap on every dollar of revenue. On growth, QUALYS, INC. posted the faster year-over-year revenue change (10.1% vs -22.7%). QUALYS, INC. produced more free cash flow last quarter ($74.9M vs $-36.6M). Over the past eight quarters, QUALYS, INC.'s revenue compounded faster (9.6% CAGR vs -11.5%).
PTC Therapeutics, Inc. is a US pharmaceutical company focused on the development of orally administered small molecule drugs and gene therapy which regulate gene expression by targeting post-transcriptional control (PTC) mechanisms in orphan diseases.
Qualys, Inc. is an American technology firm based in Foster City, California, specializing in cloud security, compliance and related services.
PTCT vs QLYS — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $164.7M | $175.3M |
| Net Profit | $-135.0M | $53.1M |
| Gross Margin | — | 83.4% |
| Operating Margin | -43.3% | 33.6% |
| Net Margin | -82.0% | 30.3% |
| Revenue YoY | -22.7% | 10.1% |
| Net Profit YoY | -104.8% | 20.9% |
| EPS (diluted) | $-1.63 | $1.47 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $164.7M | $175.3M | ||
| Q3 25 | $211.0M | $169.9M | ||
| Q2 25 | $178.9M | $164.1M | ||
| Q1 25 | $1.2B | $159.9M | ||
| Q4 24 | $213.2M | $159.2M | ||
| Q3 24 | $196.8M | $153.9M | ||
| Q2 24 | $186.7M | $148.7M | ||
| Q1 24 | $210.1M | $145.8M |
| Q4 25 | $-135.0M | $53.1M | ||
| Q3 25 | $15.9M | $50.3M | ||
| Q2 25 | $-64.8M | $47.3M | ||
| Q1 25 | $866.6M | $47.5M | ||
| Q4 24 | $-65.9M | $44.0M | ||
| Q3 24 | $-106.7M | $46.2M | ||
| Q2 24 | $-99.2M | $43.8M | ||
| Q1 24 | $-91.6M | $39.7M |
| Q4 25 | — | 83.4% | ||
| Q3 25 | — | 83.6% | ||
| Q2 25 | — | 82.4% | ||
| Q1 25 | — | 81.9% | ||
| Q4 24 | — | 81.8% | ||
| Q3 24 | — | 81.3% | ||
| Q2 24 | — | 82.2% | ||
| Q1 24 | — | 81.3% |
| Q4 25 | -43.3% | 33.6% | ||
| Q3 25 | 1.4% | 35.3% | ||
| Q2 25 | -19.5% | 31.3% | ||
| Q1 25 | 82.5% | 32.4% | ||
| Q4 24 | -76.2% | 31.0% | ||
| Q3 24 | -27.7% | 29.2% | ||
| Q2 24 | -21.5% | 32.3% | ||
| Q1 24 | -21.6% | 30.7% |
| Q4 25 | -82.0% | 30.3% | ||
| Q3 25 | 7.5% | 29.6% | ||
| Q2 25 | -36.3% | 28.8% | ||
| Q1 25 | 73.7% | 29.7% | ||
| Q4 24 | -30.9% | 27.6% | ||
| Q3 24 | -54.2% | 30.0% | ||
| Q2 24 | -53.1% | 29.4% | ||
| Q1 24 | -43.6% | 27.2% |
| Q4 25 | $-1.63 | $1.47 | ||
| Q3 25 | $0.20 | $1.39 | ||
| Q2 25 | $-0.83 | $1.29 | ||
| Q1 25 | $10.04 | $1.29 | ||
| Q4 24 | $-0.85 | $1.19 | ||
| Q3 24 | $-1.39 | $1.24 | ||
| Q2 24 | $-1.29 | $1.17 | ||
| Q1 24 | $-1.20 | $1.05 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $1.9B | $250.3M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $-205.3M | $561.2M |
| Total Assets | $2.9B | $1.1B |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $1.9B | $250.3M | ||
| Q3 25 | $1.7B | $225.3M | ||
| Q2 25 | $2.0B | $194.0M | ||
| Q1 25 | $2.0B | $290.7M | ||
| Q4 24 | $1.1B | $232.2M | ||
| Q3 24 | $1.0B | $235.4M | ||
| Q2 24 | $1.1B | $281.2M | ||
| Q1 24 | $884.8M | $273.8M |
| Q4 25 | $-205.3M | $561.2M | ||
| Q3 25 | $-155.8M | $529.4M | ||
| Q2 25 | $-206.5M | $508.2M | ||
| Q1 25 | $-185.8M | $498.0M | ||
| Q4 24 | $-1.1B | $477.1M | ||
| Q3 24 | $-1.1B | $449.6M | ||
| Q2 24 | $-980.2M | $427.8M | ||
| Q1 24 | $-893.9M | $404.2M |
| Q4 25 | $2.9B | $1.1B | ||
| Q3 25 | $2.6B | $1.0B | ||
| Q2 25 | $2.6B | $999.5M | ||
| Q1 25 | $2.7B | $996.5M | ||
| Q4 24 | $1.7B | $973.5M | ||
| Q3 24 | $1.8B | $908.3M | ||
| Q2 24 | $1.9B | $876.6M | ||
| Q1 24 | $1.8B | $861.8M |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-34.3M | $75.7M |
| Free Cash FlowOCF − Capex | $-36.6M | $74.9M |
| FCF MarginFCF / Revenue | -22.3% | 42.8% |
| Capex IntensityCapex / Revenue | 1.4% | 0.4% |
| Cash ConversionOCF / Net Profit | — | 1.42× |
| TTM Free Cash FlowTrailing 4 quarters | $702.3M | $304.4M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-34.3M | $75.7M | ||
| Q3 25 | $-66.3M | $90.4M | ||
| Q2 25 | $-58.3M | $33.8M | ||
| Q1 25 | $870.1M | $109.6M | ||
| Q4 24 | $-30.0M | $47.7M | ||
| Q3 24 | $-77.0M | $61.0M | ||
| Q2 24 | $-71.5M | $49.8M | ||
| Q1 24 | $70.8M | $85.5M |
| Q4 25 | $-36.6M | $74.9M | ||
| Q3 25 | $-69.7M | $89.5M | ||
| Q2 25 | $-59.6M | $32.4M | ||
| Q1 25 | $868.4M | $107.5M | ||
| Q4 24 | $-33.8M | $41.9M | ||
| Q3 24 | $-77.5M | $57.6M | ||
| Q2 24 | $-78.8M | $48.8M | ||
| Q1 24 | $61.2M | $83.5M |
| Q4 25 | -22.3% | 42.8% | ||
| Q3 25 | -33.1% | 52.7% | ||
| Q2 25 | -33.3% | 19.8% | ||
| Q1 25 | 73.8% | 67.3% | ||
| Q4 24 | -15.8% | 26.3% | ||
| Q3 24 | -39.4% | 37.4% | ||
| Q2 24 | -42.2% | 32.8% | ||
| Q1 24 | 29.1% | 57.2% |
| Q4 25 | 1.4% | 0.4% | ||
| Q3 25 | 1.6% | 0.5% | ||
| Q2 25 | 0.7% | 0.8% | ||
| Q1 25 | 0.1% | 1.3% | ||
| Q4 24 | 1.8% | 3.7% | ||
| Q3 24 | 0.3% | 2.2% | ||
| Q2 24 | 4.0% | 0.7% | ||
| Q1 24 | 4.6% | 1.4% |
| Q4 25 | — | 1.42× | ||
| Q3 25 | -4.17× | 1.80× | ||
| Q2 25 | — | 0.71× | ||
| Q1 25 | 1.00× | 2.31× | ||
| Q4 24 | — | 1.09× | ||
| Q3 24 | — | 1.32× | ||
| Q2 24 | — | 1.14× | ||
| Q1 24 | — | 2.15× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
PTCT
Segment breakdown not available.
QLYS
| Sales Channel Through Intermediary | $88.6M | 51% |
| Sales Channel Directly To Consumer | $86.7M | 49% |
